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FrailtyFiATNCT00783159

Fit in the Aged by Professional Training

A study testing Power Training and Strength Training in people with Frailty and Sarcopenia, run by University of Erlangen-Nürnberg Medical School at 1 site in Germany.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons. Read more about this study

Who is it for?
Ages 65 years and older
Conditions the study is for
Frailty, Sarcopenia
What is being tested?
Power Training and Strength Training
Type of treatment
Surgery or procedure
Could I receive a placebo?
No, everyone receives an active treatment
How many people
69 participants
Where
1 siteGermany
Study dates
Jun 2008to May 2010
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 65 years and older
  • All sexes
  • No healthy volunteers
  • Older adult

Who may be able to join

  • Prefrailty according to the frailty score of Fried

Who cannot join

  • Sarcoidosis
  • Nephrolithiasis
  • Plasmacytoma
  • COPD
  • Inflammatory bowel disease
  • Rheumatoid arthritis
Show all 13Show fewer
  • History of cancer
  • Instable heart disease
  • Depression (GDS>=6)
  • Dementia (MMSE<=24)
  • BMI>35kg/m²
  • Current attendance of muscle training
  • Medication: immunosuppressive drugs

Trial locations and contacts

1 site in 1 country.

Germany1 site

  • Institute of Biomedicine of Aging

    Nuremberg, 90419

Other trials in Germany

About this study

Official title: The Effect of Different Training Modalities and Vitamin D Supplementation on Functionality in Prefrail Elderly Persons

This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.

Read the detailed description

This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested.

After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.

Conditions
Frailty, Sarcopenia
Being tested
Power Training, Strength Training, Control
Keywords
Muscle power, Frailty, Exercise, Vitamin D
Medical subject headings
Frailty, Sarcopenia, Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Power TrainingProcedure or surgery

    Power training, Vitamin D substitution

  • Strength TrainingProcedure or surgery

    Strength training, Vitamin D substitution

  • ControlOther

    Vitamin D substitution, Lifestyle consultation

Study groups in NCT00783159
Study groupRoleWhat they receive
AExperimentalTraining I
Receives: Procedure: Power Training
BExperimentalTraining II
Receives: Procedure: Strength Training
CActive comparatorControl
Receives: Other: Control

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Short physical performance battery

    Measured: 3 months after intervention

Secondary outcomes (1)

  1. Muscle strength and muscle power

    Measured: 3 months after intervention

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted31 Oct 2008 (estimated)
  2. Study startJun 2008
  3. Primary completionDec 2009
  4. Study completionMay 2010

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
69 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT00783159
Sponsor's protocol ID
32.5.8051.0113.0
Acronym
FiAT
Status last verified
Dec 2020
First submitted
30 Oct 2008
Last updated
14 Dec 2020
Results posted
No
Data monitoring committee
No

Publications

  • Rippl M, Bidlingmaier M, Deissler L, Martini S, Mueller K, Schluessel S, Schmidmaier R, Schweizer JROL, Tausendfreund O, Welscher L, Drey M. Strength but not power training increases soluble alpha klotho levels in pre-frail older adults. Exp Gerontol. 2026 Jan;213:113002. doi: 10.1016/j.exger.2025.113002. Epub 2025 Dec 13.

    PubMed 41397660

  • Schaupp A, Bidlingmaier M, Martini S, Reincke M, Schluessel S, Schmidmaier R, Drey M. Resistance training-induced improvement in physical function is not associated to changes in endocrine somatotropic activity in prefrail older adults. Arch Gerontol Geriatr. 2022 Nov-Dec;103:104792. doi: 10.1016/j.archger.2022.104792. Epub 2022 Aug 14.

    PubMed 36037722

  • Zech A, Drey M, Freiberger E, Hentschke C, Bauer JM, Sieber CC, Pfeifer K. Residual effects of muscle strength and muscle power training and detraining on physical function in community-dwelling prefrail older adults: a randomized controlled trial. BMC Geriatr. 2012 Nov 7;12:68. doi: 10.1186/1471-2318-12-68.

    PubMed 23134737

  • Drey M, Zech A, Freiberger E, Bertsch T, Uter W, Sieber CC, Pfeifer K, Bauer JM. Effects of strength training versus power training on physical performance in prefrail community-dwelling older adults. Gerontology. 2012;58(3):197-204. doi: 10.1159/000332207. Epub 2011 Nov 3.

    PubMed 22056537

Questions about this trial

What is this clinical trial studying?

A study testing Power Training and Strength Training in people with Frailty and Sarcopenia, run by University of Erlangen-Nürnberg Medical School at 1 site in Germany.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 14 Dec 2020. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Short physical performance battery (time frame: 3 months after intervention). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT00783159, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Dec 2020.

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