Metabolic DisorderNCT02573103
Air Pollution and Cardiovascular Disease
An observational study of Metabolic Disorder, run by WeiHuang.
Trial summary
To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease. Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Metabolic Disorder
- How many people
- 73 participants
- Where
- No sites listed yet
- Study dates
- Nov 2014to Jan 2016
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: We will maintain enrollment criteria of the in-progress study being healthy adults without CV disease or risk factors
Who may be able to join
- without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.
Who cannot join
- Screening visit BP>140/90 mm Hg, fasting glucose >126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.
About this study
To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.
- Conditions
- Metabolic Disorder
- Medical subject headings
- Metabolic Diseases
What is being measured
The primary outcome is the main question the study is designed to answer.
Dyslipidemia
Analyzed HDL by Beckman AU5800
Measured: One year
Secondary outcomes (1)
System oxidative stress
Analyzed oxidative stress biomarkers,such as MDA by HPLC
Measured: One year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Oct 2015 (estimated)
- Study startNov 2014
- Primary completionJan 2016
- Study completionJan 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Metabolic DisorderStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 73 participants (actual)
Sponsor and investigators
- Lead sponsor
- WeiHuang
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, WeiHuang, Peking University
- Investigators
- Wei Huang, PhD, Principal investigator, Peking University School of Public Health
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02573103
- Sponsor's protocol ID
- WHuang
- Status last verified
- Jul 2018
- First submitted
- 28 Sep 2015
- Last updated
- 12 Jul 2018
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 12 Jul 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Air Pollution and Cardiovascular Disease
- ClinicalTrials.gov ID
- NCT02573103
- Acronym / sponsor ID
- WHuang
- Conditions
- Metabolic Disorder
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 73 participants (actual)
- Lead sponsor
- WeiHuangUniversity, hospital or other
- Study start
- Nov 2014
- Primary completion
- Jan 2016 (actual)
- Study completion
- Jan 2016 (actual)
- First posted
- 9 Oct 2015 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- We will maintain enrollment criteria of the in-progress study being healthy adults without CV disease or risk factors
Key inclusion criteria (1 listed)
- without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.
Key exclusion criteria (1 listed)
- Screening visit BP>140/90 mm Hg, fasting glucose >126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Dyslipidemia
Time frame: One year
Analyzed HDL by Beckman AU5800
1 secondary outcome
System oxidative stress
Time frame: One year
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jul 2018.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Wei Huang, PhD principal investigator
Peking University School of Public Health
Questions about this trial
What is this clinical trial studying?
An observational study of Metabolic Disorder, run by WeiHuang.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Jul 2018. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dyslipidemia (time frame: One year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jul 2018; AzTrials last refreshed its copy on 30 Oct 2026.