Video Assisted Thoracoscopic SurgeryNCT03949790
ESPB Combined With Intercostal Nerve Block in VATs
A study testing ESPB and Intercostal nerve block and Intercostal nerve block in people with Video Assisted Thoracoscopic Surgery, run by Seoul National University Hospital at 1 site in South Korea.
Trial summary
A randomized prospective trial to test the effect of additional Erector Spinae Plane Block (ESPB) with intercostal nerve block during video assisted thoracoscopic surgery. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Video Assisted Thoracoscopic Surgery
- What is being tested?
- ESPB and Intercostal nerve block and Intercostal nerve block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteSouth Korea
- Study dates
- 18 Jun 2019to 1 Jul 2020
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Wedge Resection or Lobectomy under VATS approach.
Who cannot join
- Age < 20 years
- Patients who has anatomical abnormality in any spine
- Patients who has skin infection near to be the present procedure site
- Intercostal nerve block is not performed during surgery
- Previous lung surgery history of affected side
Trial locations and contacts
1 site in 1 country.
South Korea1 site, 1 recruiting
- Recruiting
SMG - SNU Boramae Medical Center
Seoul, 07061
Tae Kyong Kim, MD, 82-2-2072-2467, ktkktk@gmail.com
About this study
Official title: Erector Spinae Plane Block Combined With Intercostal Nerve Block in Video Assisted Thoracoscopic Surgery: a Randomized Study
A randomized prospective trial to test the effect of additional Erector Spinae Plane Block (ESPB) with intercostal nerve block during video assisted thoracoscopic surgery.
Read the detailed description
A prospective randomized trial which aims to evaluate effect of peripheral nerve block for pain management, the Erector Spinae Plane Block (ESPB) in patients undergoing video assisted thoracoscopic surgery with intercostal nerve block.
- Conditions
- Video Assisted Thoracoscopic Surgery
- Being tested
- ESPB and Intercostal nerve block, Intercostal nerve block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ESPB and Intercostal nerve blockProcedure or surgery
Erector spinae plane block + Intercostal nerve block
Intercostal nerve blockProcedure or surgery
Intercostal nerve block
| Study group | Role | What they receive |
|---|---|---|
| Intercostal block with ESPB | Active comparator | Performed ESPB in VATs with intercostal nerve block Receives: Procedure: ESPB and Intercostal nerve block |
| Intercostal block without ESPB | Active comparator | Not Performed ESPB in VATs with intercostal nerve block Receives: Procedure: Intercostal nerve block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain
VAS score (Visual Analog Scale for Pain, 0-10, higher value represent a worse outcome)
Measured: 1 hour after surgery
Secondary outcomes (5)
Postoperative Pain
VAS score (Visual Analog Scale for Pain, 0-10, higher value represent a worse outcome)
Measured: 6 hours after surgery
Postoperative Pain
VAS score (Visual Analog Scale for Pain, 0-10, higher value represent a worse outcome)
Measured: 12 hours after surgery
Postoperative Pain
VAS score (Visual Analog Scale for Pain, 0-10, higher value represent a worse outcome)
Measured: 24 hours after surgery
Postoperative Pain
VAS score (Visual Analog Scale for Pain, 0-10, higher value represent a worse outcome)
Measured: 48 hours after surgery
Opioid consumption
cumulative total opioid consumption
Measured: postoperative 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 May 2019
- Study start18 Jun 2019
- Primary completion1 Jun 2020 (estimated)
- Study completion1 Jul 2020 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for Video Assisted Thoracoscopic SurgeryStudies of the same condition, open and under way.
- More trials run by Seoul National University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Seoul National University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tae Kyong Kim, Seoul National University Hospital
- Investigators
- Tae Kyong Kim, MD, phD, Study chair, SMG-SNU Boramae
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03949790
- Sponsor's protocol ID
- 2019-107
- Status last verified
- Sep 2019
- First submitted
- 6 May 2019
- Last updated
- 24 Sep 2019
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Chin KJ, Adhikary S, Sarwani N, Forero M. The analgesic efficacy of pre-operative bilateral erector spinae plane (ESP) blocks in patients having ventral hernia repair. Anaesthesia. 2017 Apr;72(4):452-460. doi: 10.1111/anae.13814. Epub 2017 Feb 11.
PubMed 28188621Forero M, Rajarathinam M, Adhikary S, Chin KJ. Continuous Erector Spinae Plane Block for Rescue Analgesia in Thoracotomy After Epidural Failure: A Case Report. A A Case Rep. 2017 May 15;8(10):254-256. doi: 10.1213/XAA.0000000000000478.
PubMed 28252539Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.
PubMed 27501016Hamilton DL, Manickam B. Erector spinae plane block for pain relief in rib fractures. Br J Anaesth. 2017 Mar 1;118(3):474-475. doi: 10.1093/bja/aex013. No abstract available.
PubMed 28203765Forero M, Rajarathinam M, Adhikary S, Chin KJ. Erector spinae plane (ESP) block in the management of post thoracotomy pain syndrome: A case series. Scand J Pain. 2017 Oct;17:325-329. doi: 10.1016/j.sjpain.2017.08.013. Epub 2017 Sep 12.
PubMed 28919152Kim H, Won D, Chang JE, Hwang JY, Lee JM, Kim TK. Erector spinae plane block added to intercostal nerve block versus intercostal nerve block alone for postoperative analgesia in video-assisted thoracoscopic surgery: A randomized controlled trial. PLoS One. 2026 Oct 27;21(10):e0361408. doi: 10.1371/journal.pone.0361408. eCollection 2026.
PubMed 42945162
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2019. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Erector Spinae Plane Block Combined With Intercostal Nerve Block in Video Assisted Thoracoscopic Surgery: a Randomized Study
- ClinicalTrials.gov ID
- NCT03949790
- Acronym / sponsor ID
- 2019-107
- Conditions
- Video Assisted Thoracoscopic Surgery
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Seoul National University HospitalUniversity, hospital or other
- Study start
- 18 Jun 2019 (actual)
- Primary completion
- 1 Jun 2020 (estimated)
- Study completion
- 1 Jul 2020 (estimated)
- First posted
- 14 May 2019 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A randomized prospective trial to test the effect of additional Erector Spinae Plane Block (ESPB) with intercostal nerve block during video assisted thoracoscopic surgery.
Detailed description
A prospective randomized trial which aims to evaluate effect of peripheral nerve block for pain management, the Erector Spinae Plane Block (ESPB) in patients undergoing video assisted thoracoscopic surgery with intercostal nerve block.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Intercostal block with ESPB | Active comparator | Procedure: ESPB and Intercostal nerve blockPerformed ESPB in VATs with intercostal nerve block |
| Intercostal block without ESPB | Active comparator | Procedure: Intercostal nerve blockNot Performed ESPB in VATs with intercostal nerve block |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Wedge Resection or Lobectomy under VATS approach.
Key exclusion criteria (5 listed)
- Age < 20 years
- Patients who has anatomical abnormality in any spine
- Patients who has skin infection near to be the present procedure site
- Intercostal nerve block is not performed during surgery
- Previous lung surgery history of affected side
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ESPB and Intercostal nerve blockErector spinae plane block + Intercostal nerve block | Procedure or surgery | Intercostal block with ESPB |
| Intercostal nerve blockIntercostal nerve block | Procedure or surgery | Intercostal block without ESPB |
Primary outcome
Postoperative Pain
Time frame: 1 hour after surgery
VAS score (Visual Analog Scale for Pain, 0-10, higher value represent a worse outcome)
5 secondary outcomes
Postoperative Pain
Time frame: 6 hours after surgery
Postoperative Pain
Time frame: 12 hours after surgery
Postoperative Pain
Time frame: 24 hours after surgery
Postoperative Pain
Time frame: 48 hours after surgery
Opioid consumption
Time frame: postoperative 24 hours
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2019.
- Background: PubMed 28188621Chin KJ, Adhikary S, Sarwani N, Forero M. The analgesic efficacy of pre-operative bilateral erector spinae plane (ESP) blocks in patients having ventral hernia repair. Anaesthesia. 2017 Apr;72(4):452-460. doi: 10.1111/anae.13814. Epub 2017 Feb 11.
- Background: PubMed 28252539Forero M, Rajarathinam M, Adhikary S, Chin KJ. Continuous Erector Spinae Plane Block for Rescue Analgesia in Thoracotomy After Epidural Failure: A Case Report. A A Case Rep. 2017 May 15;8(10):254-256. doi: 10.1213/XAA.0000000000000478.
- Background: PubMed 27501016Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.
- Background: PubMed 28203765Hamilton DL, Manickam B. Erector spinae plane block for pain relief in rib fractures. Br J Anaesth. 2017 Mar 1;118(3):474-475. doi: 10.1093/bja/aex013. No abstract available.
- Background: PubMed 28919152Forero M, Rajarathinam M, Adhikary S, Chin KJ. Erector spinae plane (ESP) block in the management of post thoracotomy pain syndrome: A case series. Scand J Pain. 2017 Oct;17:325-329. doi: 10.1016/j.sjpain.2017.08.013. Epub 2017 Sep 12.
- Derived from this study: PubMed 42945162Kim H, Won D, Chang JE, Hwang JY, Lee JM, Kim TK. Erector spinae plane block added to intercostal nerve block versus intercostal nerve block alone for postoperative analgesia in video-assisted thoracoscopic surgery: A randomized controlled trial. PLoS One. 2026 Oct 27;21(10):e0361408. doi: 10.1371/journal.pone.0361408. eCollection 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tae Kyong Kim, MD, phD study chair
SMG-SNU Boramae
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ESPB and Intercostal nerve block and Intercostal nerve block in people with Video Assisted Thoracoscopic Surgery, run by Seoul National University Hospital at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 24 Sep 2019. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Tae Kyong Kim, Md, phD (+82-2-870-2519, ktkktk@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain (time frame: 1 hour after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03949790, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2019.