Tooth ExtractionNCT04705181
The Indications of First Molar Extraction at Tufts University, School of Dental Medicine
An observational study of Tooth Extraction, run by Tufts University at 1 site in United States.
Trial summary
The aim of the present study is to investigate whether there has been a change of criteria for tooth extraction at Tufts University School of Dental Medicine (TUSDM) from 2005 to 2018. The primary outcome is the change of mean of radiographic interproximal bone loss of extracted teeth. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Tooth Extraction
- How many people
- 240 participants
- Where
- 1 siteUnited States
- Study dates
- 19 Mar 2020to 30 Jun 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patients who had fully-erupted first molar extraction (tooth number #3 or #14 or #19 or #30) under CDT code of D7140 (Extraction, erupted tooth or exposed root) and D7210 (Extraction, erupted tooth requiring removal of bone and/or sectioning of tooth, and including elevation of mucoperiosteal flap if indicated) at TUSDM
Who may be able to join
- Patients who had fully-erupted first molar extraction (tooth number #3 or #14 or #19 or #30) under Code on Dental Procedures and Nomenclature (CDT) code of D7140 (Extraction, erupted tooth or exposed root) and D7210 (Extraction, erupted tooth requiring removal of bone and/or sectioning of tooth, and including elevation of mucoperiosteal flap if indicated) at TUSDM.
- The electronic records must include the following data:
- Gender
- Age
- Comprehensive periodontal chart, including probing depth (PD), clinical attachment level (CAL), furcation involvement and mobility. The periodontal chart has to be recorded within 12 months before tooth extraction
- Periapical radiograph and bite-wing radiographs of extracted tooth. The radiographs have to be taken within 12 months before tooth extraction
Show all 16Show fewer
- Reasons for tooth extraction
- Part 2:
- Patients who had:
- Fully-erupted first and second molars (tooth number #2, #3, #14, #15, #18, #19, #30, #31) that were extracted under CDT codes D7140 (Extraction, erupted tooth or exposed root) or D7210 (Extraction, erupted tooth requiring removal of bone and/or sectioning of tooth, and including elevation of mucoperiosteal flap if indicated).
- The same extracted tooth were replace with dental implant placement under CDT code D6010 (Surgical placement, endosteal implant) within 24 months after extraction.
- The electronic records must include the following data
- Sex
- Age
- Dental records including:
- Periapical radiograph of the tooth before extraction: the radiographs have to be taken within 12 months before tooth extraction, including one or more of probing depth (PD), clinical attachment level (CAL), furcation involvement and tooth mobility.
Who cannot join
- Absence of tooth distal to extracted tooth.
- Clinical decision for tooth extraction may be affected by tooth location. When the tooth is the distal abutment in the dentition, clinicians tend to keep the tooth even if the prognosis is compromised.
- Presence of dental implant adjacent to extracted tooth a. Clinical decision for tooth extraction may be affected by adjacent dental implants.
Trial locations and contacts
1 site in 1 country.
United States1 site
Tufts University School of Dental Medicine
Boston, Massachusetts, 02111
About this study
Official title: The Indications of First Molar Extraction at Tufts University, School of Dental Medicine--A 14-year Retrospective Study
The aim of the present study is to investigate whether there has been a change of criteria for tooth extraction at Tufts University School of Dental Medicine (TUSDM) from 2005 to 2018. The primary outcome is the change of mean of radiographic interproximal bone loss of extracted teeth. The secondary outcomes are changes of other parameters (periodontal, endodontic and restorative) of extracted teeth and reasons for extraction.
Read the detailed description
The purpose of the present study is to quantitatively evaluate the change in tooth extraction at school setting over the past 14 years.
Aims The aim of the present study is to investigate whether there has been a change of criteria for tooth extraction at Tufts University School of Dental Medicine (TUSDM) from 2005 to 2018. The primary outcome is the change of mean of radiographic interproximal bone loss of extracted teeth. The secondary outcomes are changes of other parameters (periodontal, endodontic and restorative) of extracted teeth and reasons for extraction.
Hypothesis Criteria for extraction of first molar teeth has changed between 2005 and 2018 toward early extraction of teeth with less severe periodontal and other conditions.
Significance Currently, there is not study presenting the quantified data for criteria change for tooth extraction. Also, determining whether to extract a tooth or not actually requires taking several clinical parameters into consideration. The present study will give clinicians a broad review of the change in clinical decision making for tooth extraction.
Materials and Methods Retrospective chart review among patients in TUSDM Pre-doctoral and Post-doctoral Group Practices The study setting is among patients who received dental treatments at TUSDM. The database will be retrospectively reviewed by patients' electronic records in TUSDM Postgraduate (PG) and Undergraduate (UG) clinics from 01/01/2005 till 12/31/2018.
- Conditions
- Tooth Extraction
What is being measured
The primary outcome is the main question the study is designed to answer.
Part 1: Change in mean of radiographic interproximal bone loss of extracted teeth
- All the measurements are based on the following reference points projected onto the theoretical tooth long axis
- Cemento-enamel junction (CEJ); if there is dental restoration or prosthesis on tooth making CEJ undetectable on the radiographs, the apical margin of dental restoration or prosthesis will be used as CEJ
- The most apical points of mesial and distal interproximal bone height
- The apex of root
- The radiographic mesial and distal bone loss will be determined by the proportion of the distance between bone height to apex and the distance between CEJ to apex, projected on the tooth axis
- The greater bone loss of the mesial and distal sides on radiographs will be used for further analysis
Measured: 2005-2018
Part 2: Change of criteria for tooth extraction
The aim for sub-project 2 represent an extension of the Aim for Subproject 1 outlined above. This sub-project will investigate whether there has been a change of criteria for tooth extraction at TUSDM from 2007 to 2018 specifically for and limited to molar teeth that were extracted and subsequently replaced with dental implants.
Criteria for extraction of first molar teeth has changed between 2007 and 2018 toward early extraction of teeth with less severe periodontal and other conditions.
Measured: 2007-2018
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Jan 2021
- Study start19 Mar 2020
- Primary completion30 Jun 2027 (estimated)
- Study completion30 Jun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth ExtractionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Retrospective
- Enrolment
- 240 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tufts University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Bjorn Steffensen, Tufts University
- Investigators
- Bjorn Steffensen, DDS, MS, PhD, Principal investigator, Tufts University School of Dental Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04705181
- Sponsor's protocol ID
- STUDY00000314
- Status last verified
- Oct 2026
- First submitted
- 8 Jan 2021
- Last updated
- 19 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Indications of First Molar Extraction at Tufts University, School of Dental Medicine--A 14-year Retrospective Study
- ClinicalTrials.gov ID
- NCT04705181
- Acronym / sponsor ID
- STUDY00000314
- Conditions
- Tooth Extraction
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 240 participants (estimated)
- Lead sponsor
- Tufts UniversityUniversity, hospital or other
- Study start
- 19 Mar 2020 (actual)
- Primary completion
- 30 Jun 2027 (estimated)
- Study completion
- 30 Jun 2028 (estimated)
- First posted
- 12 Jan 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the present study is to investigate whether there has been a change of criteria for tooth extraction at Tufts University School of Dental Medicine (TUSDM) from 2005 to 2018. The primary outcome is the change of mean of radiographic interproximal bone loss of extracted teeth. The secondary outcomes are changes of other parameters (periodontal, endodontic and restorative) of extracted teeth and reasons for extraction.
Detailed description
The purpose of the present study is to quantitatively evaluate the change in tooth extraction at school setting over the past 14 years.
Aims The aim of the present study is to investigate whether there has been a change of criteria for tooth extraction at Tufts University School of Dental Medicine (TUSDM) from 2005 to 2018. The primary outcome is the change of mean of radiographic interproximal bone loss of extracted teeth. The secondary outcomes are changes of other parameters (periodontal, endodontic and restorative) of extracted teeth and reasons for extraction.
Hypothesis Criteria for extraction of first molar teeth has changed between 2005 and 2018 toward early extraction of teeth with less severe periodontal and other conditions.
Significance Currently, there is not study presenting the quantified data for criteria change for tooth extraction. Also, determining whether to extract a tooth or not actually requires taking several clinical parameters into consideration. The present study will give clinicians a broad review of the change in clinical decision making for tooth extraction.
Materials and Methods Retrospective chart review among patients in TUSDM Pre-doctoral and Post-doctoral Group Practices The study setting is among patients who received dental treatments at TUSDM. The database will be retrospectively reviewed by patients' electronic records in TUSDM Postgraduate (PG) and Undergraduate (UG) clinics from 01/01/2005 till 12/31/2018.
Study design
- Observational model
- Other
- Time perspective
- Retrospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients who had fully-erupted first molar extraction (tooth number #3 or #14 or #19 or #30) under CDT code of D7140 (Extraction, erupted tooth or exposed root) and D7210 (Extraction, erupted tooth requiring removal of bone and/or sectioning of tooth, and including elevation of mucoperiosteal flap if indicated) at TUSDM
Key inclusion criteria (16 listed)
- Patients who had fully-erupted first molar extraction (tooth number #3 or #14 or #19 or #30) under Code on Dental Procedures and Nomenclature (CDT) code of D7140 (Extraction, erupted tooth or exposed root) and D7210 (Extraction, erupted tooth requiring removal of bone and/or sectioning of tooth, and including elevation of mucoperiosteal flap if indicated) at TUSDM.
- The electronic records must include the following data:
- Patients who had:
- The electronic records must include the following data
Key exclusion criteria (3 listed)
- Absence of tooth distal to extracted tooth.
- Presence of dental implant adjacent to extracted tooth a. Clinical decision for tooth extraction may be affected by adjacent dental implants.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Part 1: Change in mean of radiographic interproximal bone loss of extracted teeth
Time frame: 2005-2018
* All the measurements are based on the following reference points projected onto the theoretical tooth long axis * Cemento-enamel junction (CEJ); if there is dental restoration or prosthesis on tooth making CEJ undetectable on the radiographs, the apical margin of dental restoration or prosthesis will be used as CEJ * The most apical points of mesial and distal interproximal bone height * The apex of root * The radiographic mesial and distal bone loss will be determined by the proportion of the distance between bone height to apex and the distance between CEJ to apex, projected on the tooth axis * The greater bone loss of the mesial and distal sides on radiographs will be used for further analysis
Part 2: Change of criteria for tooth extraction
Time frame: 2007-2018
The aim for sub-project 2 represent an extension of the Aim for Subproject 1 outlined above. This sub-project will investigate whether there has been a change of criteria for tooth extraction at TUSDM from 2007 to 2018 specifically for and limited to molar teeth that were extracted and subsequently replaced with dental implants. Criteria for extraction of first molar teeth has changed between 2007 and 2018 toward early extraction of teeth with less severe periodontal and other conditions.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Bjorn Steffensen, DDS, MS, PhD principal investigator
Tufts University School of Dental Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Tooth Extraction, run by Tufts University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 16 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Part 1: Change in mean of radiographic interproximal bone loss of extracted teeth (time frame: 2005-2018). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026; AzTrials last refreshed its copy on 7 Nov 2026.