Clinical trials: Acute Heart Failure
Heart Failure, Heart Failure With Preserved Ejection Fraction
Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program
This is a pilot randomized trial of the BAMS-HF (Balance, Aerobic capacity, Mobility and Strength in patients hospitalized for Heart Failure) Program versus usual care.
- Conditions
- Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure, Systolic, Heart Failure, Diastolic
- Trial name
- BAMS-HF (NCT04281849)
- Testing
- BAMS-HF Program
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Eastern Colorado Health Care System
Acute Coronary Syndrome, Congestive Heart Failure
Mind-body Interventions in Cardiac Patients
This study is investigating whether a series of psychological exercises, called positive psychology, provides benefit to patients who have been hospitalized for heart disease (an 'acute coronary syndrome' or heart failure).
- Trial name
- NCT01270568
- Testing
- Positive Psychology, Relaxation Response, Recollection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Acute Heart Failure
Consultation at 8 Days to Reduce Hospitalisations in Heart Failure Patient
Evaluate the benefit of systematic appointment with a cardiologist a week after hospitalisation for acute heart failure. Randomised, endpoint: number of day alive out of hospital during 6 months
- Trial name
- CHIC (NCT01834833)
- Testing
- Follow-up
- Where
- France
- Volunteers
- 326 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pulmonary Embolism
Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism
Currently there is no clear guidance for the treatment of moderate risk of pulmonary embolism. The aim of the study is to compare two different therapeutic modalities - standard anticoagulation versus thrombolytic treatment…
- Trial name
- CONTACT-SPE (NCT02132689)
- Testing
- Actilyse (Thrombolytic therapy), Heparine (Standard anticoagulation therapy)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Kidney Diseases, Diabetes Mellitus
Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy
The aim of this prospective, randomized, controlled study is to investigate the effect of pretreatment with intravenous Alprostadil on the incidence of CIN in a high-risk population of patients with both type 2 diabetes mellitus…
- Conditions
- Kidney Diseases, Diabetes Mellitus, Acute Kidney Injury, Kidney Failure, Chronic
- Trial name
- NCT01722513
- Testing
- Alprostadil ﹠control
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Acute Kidney Injury, Renal Insufficiency
Novel Biomarkers for Risk Prediction of Contrast-Induced Acute Kidney Injury Post Coronary Angiography
Contrast-induced acute kidney injury (CI-AKI) has been recognized as the third most common cause of hospital acquired AKI, after hypotension-associated hypo-perfusion and post-operative AKI.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Kidney Diseases
- Trial name
- NORDICA (NCT02263820)
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Sapere Bio
Kidney Failure, Acute, Contrast Media
Bicarbonate v Saline to Prevent Contrast Nephropathy
Slowing of kidney function occurs in a minority of people given dye during angiography. The purpose of this study is to compare two different types of fluid given into a vein to reduce the risk of kidney injury: salt in water or…
- Trial name
- NCT00384995
- Testing
- 0.9% (154 mEq/L) IV Sodium Chloride, 1/6 M (166 mEq/L) IV Sodium Bicarbonate
- Where
- 5 sites in Italy
- Volunteers
- 61 people
- Sponsor
- Italian Society of Nephrology
Heart Failure
Safety and Efficacy Study of Istaroxime in Acute Decompensated Heart Failure Patients
The purpose of this study is to assess the safety and efficacy of istaroxime in patients hospitalized for Acute Decompensated Heart Failure (ADHF) not requiring inotropic therapy.This will be done by comparing the hemodynamic…
- Trial name
- NCT00838253
- Testing
- Istaroxime
- Sponsor
- Debiopharm International SA
Acute Kidney Injury, Critical Illness
Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers
The aim of this study was to identify and validate novel biomarkers for predict acute kidney injury (AKI) subphenotype, major adverse kidney events and other poor outcomes.
- Conditions
- Acute Kidney Injury, Critical Illness, Kidney Failure
- Trial name
- NCT06351813
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Myocardial Infarction, Heart Failure
The Benefits of Wearable AI in Post-Discharge Management of AMI Patients
Myocardial infarction (MI) remains a major threat to human health. Although interventional treatment techniques have advanced rapidly, many patients still experience major adverse cardiovascular events (MACE) and require hospital…
- Trial name
- NCT07288229
- Testing
- Optimized Integrated Management Based on AI-Guided Wearable Data
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Acute Respiratory Failure, Heart Failure
Tracheostomy in ICU With a Double Lumen Endotracheal Tube
Percutaneous tracheostomy in Intensive care unit (ICU) is performed with the use of flexible fiberoptic bronchoscope inside the conventional single lumen endotracheal tube owned by the patients.
- Conditions
- Acute Respiratory Failure, Heart Failure, Neurological Disease
- Trial name
- NCT01691222
- Testing
- Double lumen endotracheal tube tracheostomy
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Genova
Heart Failure
Patient Journey in Hospital With Acute Heart Failure
A multicentre, prospective, observational, hospital-based registry of patients with acute heart failure (AHF) those whose care was guided by a cardiologist in Turkey.
- Trial name
- JourneyHF-TR (NCT02621203)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Mehdi Zoghi
Bradyarrhythmia, Dyspnea
The Safety and Efficacy of FFR Protocol in NTUH System
FFR-guided PCI has been performed in National Taiwan University Hospital(NTUH) for many years. Nevertheless, the method of FFR measurement in NTUH is different from that in literature.
- Conditions
- Bradyarrhythmia, Dyspnea, Acute Respiratory Failure
- Trial name
- NCT03693157
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Heart Failure
Monitor Patients With Acute Heart Failure
This is a prospective, multi-center, non-randomized study to evaluate performance of an external monitor for heart failure patients
- Trial name
- ACUTE (NCT00919828)
- Testing
- Avivo System
- Volunteers
- 60 people
- Sponsor
- Corventis, Inc.
Acute Decompensated Heart Failure (ADHF)
Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure
The goal of this clinical trial is to test the hypothesis that the continuation of empagliflozin during decongestive therapy in the setting of acute decompensated and hospitalized heart failure patients is not inferior compared…
- Trial name
- EMPA-CON (NCT07038356)
- Testing
- Empagliflozin 10 MG Oral Tablet [Jardiance]
- Where
- 12 sites in Germany
- Volunteers
- 536 people
- Sponsor
- Christian Schulze
Acute Heart Failure (AHF), Congestive Heart Failure Acute
POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart Failure
Acute decompensated heart failure (ADHF) is a frequent cause of hospitalization and is associated with high morbidity and mortality.
- Conditions
- Acute Heart Failure (AHF), Congestive Heart Failure Acute, Diuretic Effect, Lung Ultrasonography Score
- Trial name
- POINTER-HF (NCT07469722)
- Testing
- Furosemide 40 Milligrams., Hydrochlorothiazide (HCTZ) 25 milligrams., Acetazolamide 250 milligrams.
- Where
- Brazil
- Volunteers
- 128 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Failure
Acute Reno-Cardiac Action of Dapagliflozin In Advanced Heart Failure Patients on Heart Transplant Waiting List
Heart failure affects 1 to 2% of the adult population in developed countries, representing about 55 million people worldwide. Advanced heart failure is a condition where the heart can no longer provide sufficient cardiac output…
- Trial name
- ARCADIA-HF (NCT06868797)
- Testing
- Biological sample for the measurement of suPAR levels.
- Where
- 11 sites in France
- Volunteers
- 103 people
- Sponsor
- Central Hospital, Nancy, France
Hypervolemic Hyponatremia
International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
To demonstrate that after 12 weeks of open-label lixivaptan treatment, serum sodium is maintained in hyponatremic patients continuing to receive lixivaptan compared to placebo during the 4 week double blind treatment period.
- Trial name
- NCT00876876
- Testing
- Lixivaptan
- Volunteers
- 300 people
- Sponsor
- CardioKine Inc.
Myocardial Infarction
Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese Patients
Statins have been shown to prevent coronary artery disease and to preserve left ventricular function in dilated cardiomyopathy. The investigators hypothesized that the early use of statins would reduce cardiovascular events…
- Trial name
- NCT00128024
- Testing
- lipid-lowering treatment
- Where
- Japan
- Volunteers
- 460 people
- Sponsor
- Kumamoto University
Acute Heart Failure (AHF)
Restrictive Versus Liberal Fluid Intake in Acute Decompensated Heart Failure
The aim of this clinical trial is to learn whether a thirst-driven, liberal fluid-intake strategy is comparable to a fluid-restriction strategy in patients hospitalized for acute decompensated heart failure (ADHF).
- Trial name
- RELIEF-AHF (NCT07400991)
- Testing
- Fluid restriction strategy, Thirst-driven, liberal fluid intake
- Where
- Denmark
- Volunteers
- 420 people
- Sponsor
- Gødstrup Hospital
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