Nutritional DeficiencyNM-in-RCIPNCT04958447
Nutritional Management in Respiratory Critically Ill Patients -an Observational Study in Mainland China
An observational study of Nutritional Deficiency, run by China-Japan Friendship Hospital at 1 site in China.
Trial summary
The important role of nutritional management in the treatment of ICU patients has been paid more and more attention. Reasonable nutritional management can improve the nutritional status of patients, reduce the risk of malnutrition, shorten the length of ICU stay, improve the quality of life of patients, and reduce the… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nutritional Deficiency
- How many people
- 1,000 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2021to 12 Aug 2021
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The patients admitted to RICU
Who may be able to join
- patients aged >18 years
- the length of RICU stays >48 hours
Who cannot join
- patients aged ≤18 years
- the length of RICU stays ≤48 hours
- patients who were admitted to RICU due to or combined with severe trauma or surgery
Trial locations and contacts
1 site in 1 country.
China1 site, 1 recruiting
- Recruiting
China-Japan Friendship hospital
Beijing, Beijing Municipality, 100028
Chen Wang, MD
About this study
The important role of nutritional management in the treatment of ICU patients has been paid more and more attention. Reasonable nutritional management can improve the nutritional status of patients, reduce the risk of malnutrition, shorten the length of ICU stay, improve the quality of life of patients, and reduce the mortality of patients, thereby improving the prognosis. Many studies have investigated the nutritional status and implementation of ICU patients. It is generally believed that the nutritional status of ICU patients is not good, and the implementation of standardization needs to be improved.The data on the nutritional status and implementation of RICU patients in mainland China is rare. Therefore, the main purpose of this study is to investigate the implementation and compliance of nutritional support treatment for RICU patients in mainland China.
Read the detailed description
Respiratory critically ill patients have their own disease metabolism and treatment methods. However, RICU medical staff generally do not pay enough attention to nutrition support treatment. The data on the nutritional status and implementation of RICU patients in China is rare. But the data plays an important role in carrying out nutrition-related research, formulating the goals of continuing education programs for nutrition support treatment, guiding the introduction of medical insurance policies and the revision of consensus. Therefore, the main purpose of this study is to investigate the implementation and compliance of nutritional support treatment for RICU patients in tertiary hospitals in mainland China, so as to lay the foundation for further relevant work.
- Conditions
- Nutritional Deficiency
- Keywords
- Nutritional Management, Respiratory Critically Ill Patients, Enteral Nutrition
- Medical subject headings
- Malnutrition
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of enteral nutrition starting within 48 hours after ICU entry
Proportion of enteral nutrition starting within 48 hours after ICU entry
Measured: 48 hours
Secondary outcomes (3)
Nutritional status and risk of malnutrition on ICU admission
To assess nutritional status and risk of malnutrition on ICU admission by NRS-2002 risk score and NUTRIC score
Measured: 48 hours
The proportion of subjects receiving>80% estimated energy target within 7 days after ICU entry
The proportion of subjects receiving>80% estimated energy target within 7 days after ICU entry
Measured: 7 days
The proportion of enteral nutrition intolerance
The proportion of enteral nutrition intolerance
Measured: 48 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Jul 2021
- Study start1 Jul 2021 (estimated)
- Primary completion1 Jul 2021 (estimated)
- Study completion12 Aug 2021 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Nutritional DeficiencyStudies of the same condition, open and under way.
- More trials run by China-Japan Friendship HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- China-Japan Friendship Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Longyan City First Hospital, First Affiliated Hospital of Wenzhou Medical University, Peking University International Hospital, Peking University People's Hospital, Peking University Shougang Hospital, General Hospital of Beijing Jingmei Group, Beijing Fangshan District Liangxiang Hospital, Beijing Hospital, Beijing Coal Group General Hospital, Beijing Rehabilitation Hospital of Capital Medical University, Beijing 302 Hospital, Cangzhou People's Hospital, Cangzhou Central Hospital, Affiliated Hospital of Chengde Medical University, Huan'an First People's Hospital, The First Affiliated Hospital of Hebei North University, Hebei Sheng Xiong Ke Yi Yuan, The Second Hospital of Hebei Medical University, North China University of Science and Technology, First Hospital of Shijiazhuang City, Tangshan Central Hospital, Zhuozhou Hospital, Second Hospital of Jilin University, The First Hospital of Jilin University, The General Hospital of Northern Theater Command, Affiliated Zhongshan Hospital of Dalian University, Dalian Municipal Central Hospital, The First Affiliated Hospital of Dalian Medical University, Central Hospital Affiliated to Shenyang Medical Collage, The Fourth Affiliated Hospital of China Medical University, First Hospital of China Medical University, Tianjin Medical University General Hospital, Tianjin Chest Hospital, Tianjin Medical University Second Hospital, Special Medical Center of the Armed Police Force, Wuhu City Second People's Hospital, The First Affiliated Hospital of Anhui Medical University, Meizhou People's Hospital, The General Hospital of Southern Theater Command, First Affiliated Hospital, Sun Yat-Sen University, Hainan People's Hospital, The First Affiliated Hospital of Zhengzhou University, The General Hospital of Eastern Theater Command, Huai an First People Hospital, Subei People's Hospital of Jiangsu Province, The First People's Hospital of Lianyungang, Nanjing No.1 Hospital, The Affiliated Jiangning Hospital of Nanjing Medical University, Second Affiliated Hospital of Soochow University, The First Affiliated Hospital of Soochow University, Suzhou Municipal Hospital, Suzhou Hospital of Traditional Chinese Medicine, Jiangxi Provincial People's Hopital, Second Affiliated Hospital of Nanchang University, The First Affiliated Hospital of Nanchang University, Shaanxi Provincial People's Hospital, First Affiliated Hospital Xi'an Jiaotong University, Xijing Hospital, Sichuan Provincial People's Hospital, No.2 People Hospital of Fuyang City, The Second Hospital of Anhui Medical University, The First Affiliated Hospital of Bengbu Medical University, Tongji Hospital, Jingzhou Central Hospital, Wuhan University, Wuhan Central Hospital, Central Command General Hospital, Second Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, Heze Municipal Hospital, Qingdao Central Hospital, Taian City Central Hospital, Yantai Yuhuangding Hospital, Zibo First Hospital, Huashan Hospital, Fudan University, Ruijin Hospital, Dongfang Hospital Affiliated to Tongji University, Changhai Hospital, Henan Provincial People's Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Taikang Xianlin Drum Tower Hospital, Xinqiao Hospital of Chongqing, The First People Hospital of Nantong City, Wuxi People's Hospital, The First People's Hospital of Changzhou, The First People's Hospital of Yunnan, People Hospital of Dali Bai Autonomous Prefecture, First Affiliated Hospital of Kunming Medical University, The Second Affiliated Hospital of Air Force Military Medical University, The 306 Hospital of People's Liberation Army, The Sixth Central Hospital of PLA, Peking University Third Hospital, People's Hospital of Xinjiang Uygur Autonomous Region, China Rehabilitation Research Center, The Third People Hospital of Datong, Dezhou People's Hospital
- Responsible party
- Principal investigator, Qingyuan Zhan, China-Japan Friendship Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04958447
- Sponsor's protocol ID
- CJFH
- Acronym
- NM-in-RCIP
- Status last verified
- Jul 2021
- First submitted
- 28 Mar 2021
- Last updated
- 12 Jul 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Huang X, Wang Y, Geng S, Liang Y, Gao F, Wang T, Zhang H, Fang J, Wang C, Gu X, Yang J, Cheng Z, Liu C, Lei W, Hu X, Luo H, Fan H, Zhang Y, Li G, Di Q, Xing L, Li Y, Tong J, Chen L, Sun W, Chen L, Wang S, Li S, Liu J, Qin H, Qiu X, Ma Z, Li Y, Zhao H, Liang R, Wang L, Gao P, Sang L, Li D, Hou P, Zhang X, Wang D, Zheng L, Hua F, Jiang J, Li X, Nie Q, Zhao H, Huang C, Ji Y, Yu H, Song L, Jin J, Li N, Qian W, Zeng J, Chen L, Sun J, He W, Guan S, Chai S, Hu S, Li G, Li J, Jiang H, Zhong X, Li J, Zhao J, Du W, Zhang J, Liu Z, van Zanten A, Tian Y, Cai Y, Zhan Q. Nutritional practices and impact of feeding adequacy on clinical outcomes in Chinese respiratory intensive care units patients: a prospective observational study (ORIENT study). Front Nutr. 2026 Jan 20;12:1719386. doi: 10.3389/fnut.2025.1719386. eCollection 2025.
PubMed 41640734
Study at a glance
From the registry record, last updated by the sponsor on 12 Jul 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Nutritional Management in Respiratory Critically Ill Patients -an Observational Study in Mainland China
- ClinicalTrials.gov ID
- NCT04958447
- Acronym / sponsor ID
- NM-in-RCIP / CJFH
- Conditions
- Nutritional Deficiency
- Keywords
- Nutritional Management, Respiratory Critically Ill Patients, Enteral Nutrition
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- China-Japan Friendship HospitalUniversity, hospital or other
- Collaborators
- Longyan City First Hospital, First Affiliated Hospital of Wenzhou Medical University, Peking University International Hospital, Peking University People's Hospital, Peking University Shougang Hospital, General Hospital of Beijing Jingmei Group, Beijing Fangshan District Liangxiang Hospital, Beijing Hospital, Beijing Coal Group General Hospital, Beijing Rehabilitation Hospital of Capital Medical University, Beijing 302 Hospital, Cangzhou People's Hospital, Cangzhou Central Hospital, Affiliated Hospital of Chengde Medical University, Huan'an First People's Hospital, The First Affiliated Hospital of Hebei North University, Hebei Sheng Xiong Ke Yi Yuan, The Second Hospital of Hebei Medical University, North China University of Science and Technology, First Hospital of Shijiazhuang City, Tangshan Central Hospital, Zhuozhou Hospital, Second Hospital of Jilin University, The First Hospital of Jilin University, The General Hospital of Northern Theater Command, Affiliated Zhongshan Hospital of Dalian University, Dalian Municipal Central Hospital, The First Affiliated Hospital of Dalian Medical University, Central Hospital Affiliated to Shenyang Medical Collage, The Fourth Affiliated Hospital of China Medical University, First Hospital of China Medical University, Tianjin Medical University General Hospital, Tianjin Chest Hospital, Tianjin Medical University Second Hospital, Special Medical Center of the Armed Police Force, Wuhu City Second People's Hospital, The First Affiliated Hospital of Anhui Medical University, Meizhou People's Hospital, The General Hospital of Southern Theater Command, First Affiliated Hospital, Sun Yat-Sen University, Hainan People's Hospital, The First Affiliated Hospital of Zhengzhou University, The General Hospital of Eastern Theater Command, Huai an First People Hospital, Subei People's Hospital of Jiangsu Province, The First People's Hospital of Lianyungang, Nanjing No.1 Hospital, The Affiliated Jiangning Hospital of Nanjing Medical University, Second Affiliated Hospital of Soochow University, The First Affiliated Hospital of Soochow University, Suzhou Municipal Hospital, Suzhou Hospital of Traditional Chinese Medicine, Jiangxi Provincial People's Hopital, Second Affiliated Hospital of Nanchang University, The First Affiliated Hospital of Nanchang University, Shaanxi Provincial People's Hospital, First Affiliated Hospital Xi'an Jiaotong University, Xijing Hospital, Sichuan Provincial People's Hospital, No.2 People Hospital of Fuyang City, The Second Hospital of Anhui Medical University, The First Affiliated Hospital of Bengbu Medical University, Tongji Hospital, Jingzhou Central Hospital, Wuhan University, Wuhan Central Hospital, Central Command General Hospital, Second Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, Heze Municipal Hospital, Qingdao Central Hospital, Taian City Central Hospital, Yantai Yuhuangding Hospital, Zibo First Hospital, Huashan Hospital, Fudan University, Ruijin Hospital, Dongfang Hospital Affiliated to Tongji University, Changhai Hospital, Henan Provincial People's Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Taikang Xianlin Drum Tower Hospital, Xinqiao Hospital of Chongqing, The First People Hospital of Nantong City, Wuxi People's Hospital, The First People's Hospital of Changzhou, The First People's Hospital of Yunnan, People Hospital of Dali Bai Autonomous Prefecture, First Affiliated Hospital of Kunming Medical University, The Second Affiliated Hospital of Air Force Military Medical University, The 306 Hospital of People's Liberation Army, The Sixth Central Hospital of PLA, Peking University Third Hospital, People's Hospital of Xinjiang Uygur Autonomous Region, China Rehabilitation Research Center, The Third People Hospital of Datong, Dezhou People's Hospital
- Study start
- 1 Jul 2021 (estimated)
- Primary completion
- 1 Jul 2021 (estimated)
- Study completion
- 12 Aug 2021 (estimated)
- First posted
- 12 Jul 2021 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The important role of nutritional management in the treatment of ICU patients has been paid more and more attention. Reasonable nutritional management can improve the nutritional status of patients, reduce the risk of malnutrition, shorten the length of ICU stay, improve the quality of life of patients, and reduce the mortality of patients, thereby improving the prognosis. Many studies have investigated the nutritional status and implementation of ICU patients. It is generally believed that the nutritional status of ICU patients is not good, and the implementation of standardization needs to be improved.The data on the nutritional status and implementation of RICU patients in mainland China is rare. Therefore, the main purpose of this study is to investigate the implementation and compliance of nutritional support treatment for RICU patients in mainland China.
Detailed description
Respiratory critically ill patients have their own disease metabolism and treatment methods. However, RICU medical staff generally do not pay enough attention to nutrition support treatment. The data on the nutritional status and implementation of RICU patients in China is rare. But the data plays an important role in carrying out nutrition-related research, formulating the goals of continuing education programs for nutrition support treatment, guiding the introduction of medical insurance policies and the revision of consensus. Therefore, the main purpose of this study is to investigate the implementation and compliance of nutritional support treatment for RICU patients in tertiary hospitals in mainland China, so as to lay the foundation for further relevant work.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The patients admitted to RICU
Key inclusion criteria (2 listed)
- patients aged >18 years
- the length of RICU stays >48 hours
Key exclusion criteria (3 listed)
- patients aged ≤18 years
- the length of RICU stays ≤48 hours
- patients who were admitted to RICU due to or combined with severe trauma or surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Proportion of enteral nutrition starting within 48 hours after ICU entry
Time frame: 48 hours
Proportion of enteral nutrition starting within 48 hours after ICU entry
3 secondary outcomes
Nutritional status and risk of malnutrition on ICU admission
Time frame: 48 hours
The proportion of subjects receiving>80% estimated energy target within 7 days after ICU entry
Time frame: 7 days
The proportion of enteral nutrition intolerance
Time frame: 48 hours
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jul 2021.
- Derived from this study: PubMed 41640734Huang X, Wang Y, Geng S, Liang Y, Gao F, Wang T, Zhang H, Fang J, Wang C, Gu X, Yang J, Cheng Z, Liu C, Lei W, Hu X, Luo H, Fan H, Zhang Y, Li G, Di Q, Xing L, Li Y, Tong J, Chen L, Sun W, Chen L, Wang S, Li S, Liu J, Qin H, Qiu X, Ma Z, Li Y, Zhao H, Liang R, Wang L, Gao P, Sang L, Li D, Hou P, Zhang X, Wang D, Zheng L, Hua F, Jiang J, Li X, Nie Q, Zhao H, Huang C, Ji Y, Yu H, Song L, Jin J, Li N, Qian W, Zeng J, Chen L, Sun J, He W, Guan S, Chai S, Hu S, Li G, Li J, Jiang H, Zhong X, Li J, Zhao J, Du W, Zhang J, Liu Z, van Zanten A, Tian Y, Cai Y, Zhan Q. Nutritional practices and impact of feeding adequacy on clinical outcomes in Chinese respiratory intensive care units patients: a prospective observational study (ORIENT study). Front Nutr. 2026 Jan 20;12:1719386. doi: 10.3389/fnut.2025.1719386. eCollection 2025.
- Individual participant dataSharing planned: No
Related trials for Nutritional Deficiency
RecruitingPhase 4
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF)
Heart Failure With Reduced Ejection Fraction, Iron Deficiency
RecruitingPhase 1/2
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
X-linked Hypophosphatemia
RecruitingObservational study
Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia
Fanconi Anemia, Inherited Bone Marrow Failure Syndrome
RecruitingPhase 4
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life
Heart Failure With Preserved Ejection Fraction, Iron Deficiencies
Not yet recruitingObservational study
Clinical Genetics Branch Eligibility Screening Survey
Melanoma, Li-Fraumeni Syndrome
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Nutritional Deficiency, run by China-Japan Friendship Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 12 Jul 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Xu Huang, M.D. (13641345816 ext. +86, huangxu1122@sina.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proportion of enteral nutrition starting within 48 hours after ICU entry (time frame: 48 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04958447, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jul 2021.