Dental Implant FailedNCT05676268
Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension
An observational study of Dental Implant Failed and Prosthesis Failure, run by University of Bern at 1 site in Switzerland.
Trial summary
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months. Read more about this study
- Who is it for?
- Ages 18 to 99 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
- What is being tested?
- Implant-supported fixed dental prostheses with cantilever extension
- Type of treatment
- Surgery or procedure
- How many people
- 35 participants
- Where
- 1 siteSwitzerland
- Study dates
- 2 Jan 2023to 31 Dec 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 99 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Patients with missing teeth rehabilitated with dental implants supporting partial fixed dental prostheses with cantilever extensions
Who may be able to join
- Patients aged ≥18 years
- Written informed consent
- Patients with systemic health or controlled medical conditions
- Patients with healthy or treated periodontal conditions
- Patients enrolled in regular supportive periodontal therapy (SPT)
- Patients without clinical signs of bruxism and/or oral parafunctions
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- 2 osseointegrated dental implants in the canine or posterior areas of maxilla and mandible following transmucosal placement and healing of 3-6 months
- Tissue level solid-screw implants with a sand-blasted and acid- etched (SLA) surface with an endosseous diameter of 3.3, 4.1 or 4.8 mm, a length of 8, 10 or 12 mm, a shoulder diameter of 4.8 mm and a supracrestal machined neck with a height of 1.8 or 2.8 mm (Straumann® Dental Implant System, Institut Straumann AG, Basel, Switzerland)
- Full-ceramic
- Utilization of prefabricated titanium abutments
- Cemented (3M™ ESPE Ketac™ Cem, Seefeld, Germany) or screw-retained fixed dental prostheses with a mesial or distal cantilever extension (FDPCs)
- Cantilever extension corresponding to 1 premolar unit (i.e., 6-7 mm)
- Absence of occlusal contacts or guidance on the cantilever extension at baseline
- Opposing dentition consisting of natural teeth or fixed or removable prosthetic restorations
- Availability of a periapical radiograph at baseline (i.e. FDPC delivery)
- Availability of PPD measurements (mm) taken at baseline at 4 sites/implant with a graduated Michigan periodontal probe (Deppeler SA, Rolle, Switzerland)
- Availability of BoP measurements (%) (Lang et al., 1986) taken at baseline at 4 sites/implant with a graduated Michigan periodontal probe (Deppeler SA, Rolle, Switzerland).
Who cannot join
- Untreated or active periodontal diseases
- Immediate implant placement (i.e., Type I implant placement according to Hämmerle et al., 2004)
- FDPCs in the aesthetic zone (i.e., replacement of maxillary or mandibular incisors)
- FDPCs supported by hollow-screw and hollow-cylinder implants
Trial locations and contacts
1 site in 1 country.
Switzerland1 site
Department of Periodontology, University of Bern
Bern, 3010
About this study
Official title: Clinical and Radiographic Outcomes of Implant-supported Full-ceramic Partial Fixed Dental Prostheses With Cantilever Extension: A Proof of Principle Study With a Follow-up of at Least 1 Year
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.
Read the detailed description
Patients with full ceramic FDPCs in anterior and posterior areas will be clinically and radiographically re-evaluated. Mesial and distal radiographic marginal bone levels (mBLs) from baseline (i.e. delivery of FDPC) to the follow-up examination were calculated and compared between implant surfaces adjacent to and distant from the cantilever extension. Implant survival rate (%), pocket probing depth (PPD), presence/ absence of bleeding on probing (BoP) and presence/absence of mechanical/technical and biological complications were recorded.
- Conditions
- Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
- Being tested
- Implant-supported fixed dental prostheses with cantilever extension
- Medical subject headings
- Prosthesis Failure, Peri-Implantitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Implant-supported fixed dental prostheses with cantilever extensionProcedure or surgery
Healthy patients in need of replacement of missing teeth with dental implants supporting partial fixed dental prostheses with cantilever extensions
| Study group | Role | What they receive |
|---|---|---|
| Patients with oral implants supporting full ceramic fixed dental prostheses | Not described Receives: Procedure: Implant-supported fixed dental prostheses with cantilever extension |
What is being measured
The primary outcome is the main question the study is designed to answer.
Implant survival rate
Percentage of dental implants present at follow-up visit
Measured: 12 months
Secondary outcomes (4)
Peri-implant marginal bone level changes
Measured: 12 months
Number of technical complications
Measured: 12 months
Number of mechanical complications
Measured: 12 months
Number of Biological complications
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jan 2023
- Study start2 Jan 2023
- Primary completion30 Sep 2023
- Study completion31 Dec 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental Implant FailedStudies of the same condition, open and under way.
- More trials run by University of BernThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 35 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Bern
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Andrea Roccuzzo, Principal investigator, University of Bern
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05676268
- Sponsor's protocol ID
- FDPs with cantilever
- Status last verified
- Jan 2026
- First submitted
- 22 Dec 2022
- Last updated
- 22 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Radiographic Outcomes of Implant-supported Full-ceramic Partial Fixed Dental Prostheses With Cantilever Extension: A Proof of Principle Study With a Follow-up of at Least 1 Year
- ClinicalTrials.gov ID
- NCT05676268
- Acronym / sponsor ID
- FDPs with cantilever
- Conditions
- Dental Implant Failed, Prosthesis Failure, Peri-Implantitis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 35 participants (actual)
- Lead sponsor
- University of BernUniversity, hospital or other
- Study start
- 2 Jan 2023 (actual)
- Primary completion
- 30 Sep 2023 (actual)
- Study completion
- 31 Dec 2023 (actual)
- First posted
- 9 Jan 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To report the clinical and radiographic outcomes of implant-supported fixed dental prostheses with full-ceramic cantilever extensions (FDPCs) after a function time ≥ 12 months.
Detailed description
Patients with full ceramic FDPCs in anterior and posterior areas will be clinically and radiographically re-evaluated. Mesial and distal radiographic marginal bone levels (mBLs) from baseline (i.e. delivery of FDPC) to the follow-up examination were calculated and compared between implant surfaces adjacent to and distant from the cantilever extension. Implant survival rate (%), pocket probing depth (PPD), presence/ absence of bleeding on probing (BoP) and presence/absence of mechanical/technical and biological complications were recorded.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients with oral implants supporting full ceramic fixed dental prostheses | – | Procedure: Implant-supported fixed dental prostheses with cantilever extension |
Who may qualify
- Ages
- 18 to 99 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with missing teeth rehabilitated with dental implants supporting partial fixed dental prostheses with cantilever extensions
Key inclusion criteria (17 listed)
- Patients aged ≥18 years
- Written informed consent
- Patients with systemic health or controlled medical conditions
- Patients with healthy or treated periodontal conditions
- Patients enrolled in regular supportive periodontal therapy (SPT)
Key exclusion criteria (4 listed)
- Untreated or active periodontal diseases
- Immediate implant placement (i.e., Type I implant placement according to Hämmerle et al., 2004)
- FDPCs in the aesthetic zone (i.e., replacement of maxillary or mandibular incisors)
- FDPCs supported by hollow-screw and hollow-cylinder implants
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Implant-supported fixed dental prostheses with cantilever extensionHealthy patients in need of replacement of missing teeth with dental implants supporting partial fixed dental prostheses with cantilever extensions | Procedure or surgery | Patients with oral implants supporting full ceramic fixed dental prostheses |
Primary outcome
Implant survival rate
Time frame: 12 months
Percentage of dental implants present at follow-up visit
4 secondary outcomes
Peri-implant marginal bone level changes
Time frame: 12 months
Number of technical complications
Time frame: 12 months
Number of mechanical complications
Time frame: 12 months
Number of Biological complications
Time frame: 12 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Andrea Roccuzzo principal investigator
University of Bern
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Dental Implant Failed and Prosthesis Failure, run by University of Bern at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 17 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Implant survival rate (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jan 2026.