Clinical trials: Prosthesis Failure
Prosthesis Durability
Complete Digital Workflow for Construction of Full Arch Implant Supported Screw Retained Restoration
This study will compare the occlusal accuracy of different techniques for recording maxillomandibular relationships in a Complete digital workflow to construct full arch implant-supported screw-retained restoration.
- Trial name
- NCT06332482
- Testing
- Implant supported screw retained prosthesis
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Rheumatoid Arthritis, Arthritis of Ankle
Vantage Mobile Bearing Total Ankle System Post Market Clinical Follow-up (Outside US)
The objectives of this study are to evaluate the performance and safety of the Vantage Mobile-Bearing Total Angle System. This study will follow subjects for a period of up to 10 years post-surgery.
- Conditions
- Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
- Trial name
- NCT05691868
- Where
- 2 sites in Spain, Switzerland
- Volunteers
- 400 people
- Sponsor
- Exactech
Rotator Cuff Tears, Hemiarthroplasty
Hemiverse Shoulder Prosthesis
This clinical trial investigates the safety and the preliminary clinical benefit of the hemiverse shoulder prosthesis. Implantation of this newly developed hemi-prosthesis is intended for patients who do not qualify for a regular…
- Trial name
- NCT04701268
- Testing
- Device: Hemiverse
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- 41Hemiverse AG
Prosthesis Durability
Direct Versus Indirect Pick up of the Locator Retentive Caps:(Within-patient Study)
The purpose of this study will be to evaluate the effect of direct and indirect pick up of the locator retentive caps and compare the clinical results with those of the manufacturer retentive force.
- Trial name
- NCT05289752
- Testing
- dental implants in the mandible, locator attachment and overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prostheses, Endosseous Dental Implant Failure
Pink Esthetic Score Around Immediate Implants Using PDDM as Jumping Gap Filling Material.
Will there be a difference in Pink Esthetic score and soft tissue changes around immediate implants in maxillary esthetic zone following grafting the jumping gap with partially demineralized dentin matrix compared with xenograft?
- Trial name
- NCT05952765
- Testing
- Immediate implant
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis
The Press Fit Condylar (P.F.C.) Sigma Rotating Platform (RP) TC3 Revision Knee in Revision Knee Arthroplasty
The purpose of this study is to evaluate the long-term clinical and functional performance of the P.F.C. Sigma Rotating Platform TC3 knee system in revision knee surgery and to determine whether the implant design results in a…
- Trial name
- TC3 (NCT00733681)
- Testing
- PFC Sigma RP TC3 Revision knee system
- Where
- 9 sites in France, Germany and 2 more
- Volunteers
- 181 people
- Sponsor
- DePuy International
Infection and Inflammatory Reaction
Pending Failure in Hard-hard Total Hip Arthroplasty
During last 6 years approximately 10.000 ceramic balls and 5.000 ceramic liners have been implanted in the region Emilia-Romagna in Italy (4 million Every single year approximately 60.000 hip prostheses are implanted in Italy.
- Trial name
- PF (NCT02427984)
- Testing
- Metal ions dosage and evaluation of local/systemic reaction, Noise registration and metal ions determination, Metal ions dosage, evaluation of local/systemic reaction, noise registration
- Where
- Italy
- Volunteers
- 148 people
- Sponsor
- Istituto Ortopedico Rizzoli
Hip Arthropathy Associated With Other Conditions, Hip Dysplasia
Long-term Survival of THA After Pelvic and/or Femoral Osteotomy
Analyze the long-term clinical and radiological outcomes of total hip arthroplasty (THA) in patients with hip dysplasia treated by pelvic osteotomy, femoral osteotomy, shelf acetabuloplasty, or a combination of these…
- Conditions
- Hip Arthropathy Associated With Other Conditions, Hip Dysplasia, Survival, Prosthesis
- Trial name
- NCT06959498
- Testing
- Total hip arthroplasty
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Dental Implants, Dental Materials
Hybrid Polyetheretherketone (PEEK)-Acrylic Resin Prostheses and the All-on-4 Concept for Full Arch Rehabilitation
It is necessary to evaluate the outcome of implant supported fixed prosthetic rehabilitations using peek material. To test this, the study design to be used will be a prospective single cohort to evaluate the long term outcome of…
- Conditions
- Dental Implants, Dental Materials, Mandible, Prosthesis Survival
- Trial name
- AO4PEEKDev (NCT04446078)
- Testing
- PEEK- acrylic resin prosthesis supported by 4 dental implants
- Where
- Portugal
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Malo Clinic
Prosthesis Failure, Dental
Clinical Success of Anterior and Posterior Crowns in a Group of Children Treated Under General Anesthesia
This incidence study aims to evaluate the clinical success of anterior and posterior full-coverage restorations among a group of Egyptian children treated under general anesthesia.
- Trial name
- NCT06201481
- Testing
- anterior and posterior full coverage crowns
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prosthesis Durability
Accuracy of Conventional and Digital Impression Techniques Used for Maxillary Hybrid Prosthesis
evaluation and comparison of the accuracy of conventional and digital impression for full arch screw retained prosthesis for edentulous maxilla.
- Trial name
- NCT05321589
- Testing
- impression techniques for implant used for maxillary screw retained hybrid prosthesis
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prosthesis Survival, Arthropathy of Knee
Evaluation of 5-year Survival and Clinical Outcomes in Patients Undergoing Total Knee Arthroplasty With a Polyethylene Tibial Component
Total knee arthroplasty (TKA) is one of the most successful procedures in orthopedic surgery for treating advanced knee osteoarthritis, providing pain relief, functional recovery, and improved quality of life.
- Trial name
- ALLPOLY-TKA (NCT07544264)
- Testing
- Total knee arthroplasty
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Istituto Ortopedico Rizzoli
Dental Prosthesis Failure
Application of 3D Printed Removable Denture Prosthesis Framework for Partial Edentulous Patients
Tooth loss is a major dental problem worldwide. A recent study in Singapore found that approximately one third of adults aged over 65 are living without any natural teeth.
- Trial name
- NCT04304222
- Testing
- 3D Printed Denture Framework
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Heart Valve Diseases, Heart; Complications, Valve, Prosthesis
Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass.
Prolonged periods of cardiopulmonary bypass (CPB) cause high levels of plasma free haemoglobin(Hb) and are associated with increased morbidity.
- Conditions
- Heart Valve Diseases, Heart; Complications, Valve, Prosthesis, Cardiac Valve Replacement Complication
- Trial name
- NCT01802619
- Testing
- inhaled nitric oxide, inhaled Nitrogen
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Xijing Hospital
Dental Prosthesis Failure
Clinical Performance of All-ceramic Posterior Crowns. A Randomized, Prospective Clinical.
This is a randomized, prospective clinical trial. The aim of the project is to assess the clinical performance of three types of tooth-supported crowns; monolithic high translucent colored zirconia, crowns of high-translucent…
- Trial name
- NCT04272112
- Testing
- IPS e.max CAD, Ivoclar Vivadent, BruxZir, Glidewell, BruxZir*, Glidewell
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Malmö University
Testicular Cancer, Testicular Torsion
Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants
To analyze the short and long term postoperative clinical outcome and patient satisfaction of silicone gel-filled testicular implants.
- Conditions
- Testicular Cancer, Testicular Torsion, Gender Dysphoria, Undescended Testes
- Trial name
- NCT05097820
- Testing
- Placement of testicular prosthesis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Aortic Valve Stenosis, Regurgitation, Aortic
Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable CoreValve Evolut R or Evolut PRO System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprotheses. The 'LYTEN' Trial
The treatment with transcatheter aortic valve implantation (TAVI) of patients with small (≤23mm) surgical bioprostheses remains a challenge due to the increased transvalvular residual gradients and high rates of severe…
- Conditions
- Aortic Valve Stenosis, Regurgitation, Aortic, Prosthesis Failure
- Trial name
- NCT03520101
- Testing
- TAVI_ViV procedure with Edwards valve, TAVI_ViV procedure with CoreValve system
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Prosthesis Survival
Implant Retained CAD-CAM Ceramic Crowns
Newly available ceramic CAD-CAM blocs containing a screw channel for chairside-made crowns to be adhesively cemented to a TiBase abutment and screw-retained to an implant are appealing to the clinician, considering the time…
- Trial name
- RCT-Scherrer (NCT04773873)
- Testing
- PFM Crowns on gold coping cast-on, hybrid abutment lithium disilicate crown, hybrid abutment ceramic polymer infiltrated crown
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Susanne Scherrer
Bioprosthesis Failure, Allograft
Comparative Analysis of Stented Biological Prosthesis Versus Aortic Allograft in Patients With Degenerative Aortic Valve Disease
The aim of the observational study is to compare safety, clinical efficacy and time-to-event survival in patients age of 60-74 years with degenerative aortic valve disease that underwent aortic valve replacement with either…
- Trial name
- BIOCHOICE (NCT07210541)
- Testing
- aortic valve/root replacement
- Volunteers
- 93 people
- Sponsor
- Chelyabinsk Regional Clinical Hospital
Dental Implant Failure, Dental Prosthesis Failure
DAMP1: The 1T1T Concept Versus Conventional Implant Loading Protocol
The One tooth - One time (1T1T) innovative approach is a straightforward and cost-effective protocol to replace a missing tooth in the posterior region (Lambert and Mainjot 2017) (see Appendix).
- Trial name
- NCT04045574
- Testing
- The 1T1T concept versus conventional implant loading protocol
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- University of Liege