Critical IllnessFluid-SEANCT06034990
ICU Fluid Utilization Survey in Southeast Asia
An observational study of Critical Illness, run by Chulalongkorn University at 1 site in Thailand.
Trial summary
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume resuscitation (representing normal condition), (2) bleeding but not septic (representing… Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Critical Illness
- What is being tested?
- 10-min online survey
- How many people
- 1,000 participants
- Where
- 1 siteThailand
- Study dates
- 31 Jan 2024to 30 Sep 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Physicians with specialty in Anesthesiology, Surgery, Critical care medicine, Pulmonology, Nephrology, General Medicine currently working in Surgical or Medical ICU in Southeast Asia in year 2023-2024
Who may be able to join
- Specialty must be in Anesthesiology, Surgery, Critical Care Medicine, Pulmonology, Nephrology, Internal Medicine, General Practitioner
- Practice must be in Southeast Asia hospitals
- Must work in Surgical ICU, Medical ICU , and/or Mixed ICU
Who cannot join
- 1.Physicians who worked in cardiac, neurology or pediatric ICUs
Trial locations and contacts
1 site in 1 country.
About this study
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume resuscitation (representing normal condition), (2) bleeding but not septic (representing normal vascular integrity but with a loss of intravascular colloids), (3) septic (representing the condition with increase vascular permeability and endothelium damage) in the ICU within Southeast Asia.
The data are collected by a 10-min online survey administered to included physicians which will be distributed via multiple online channels through representatives of each countries.
Read the detailed description
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume resuscitation (representing normal condition), (2) bleeding but not septic (representing normal vascular integrity but with a loss of intravascular colloids), (3) septic (representing the condition with increase vascular permeability and endothelium damage) in the ICU within Southeast Asia, and to determine whether co-morbidities with hypoalbuminemia, clinician specialties, hospital practice settings, geographic locations and re-imbursement limitation especially for colloids influence the practice patterns of fluid utilization in different phases in the 3 types of patients. Ultimately, the information provided by this study could also provide basic background information for the design of future clinical trials regarding fluid resuscitation strategies.
The data are collected by a 10-min online survey administered to included physicians which will be distributed via multiple online channels through representatives of each countries.
The survey will start with an inform-consent form prior to starting the survey questions which consist of 13-item questionnaire obtaining information on
- Demographics data of clinicians taking the survey on primary specialty, region or country of practice and hospital settings.
- Preferences for volume status indicators.
- Preferences for fluid resuscitation in 3 types of patients (1. Septic 2. bleeding but not septic 3. not bleeding and not septic) during resuscitation and optimization phase.
- Preferences for fluid resuscitation in the 3 types of patients with hypoalbuminemia including (1) cirrhosis (2) nephrotic syndrome (3) other significant hypoalbuminemia during resuscitation/optimization phase and stabilization phase
- The reasons for using colloids for volume expansion
- The experience of adverse reactions to albumin
- The awareness and importance of non-oncotic properties of albumin
- The impact of reimbursement for colloids on resuscitation fluid choice
- Conditions
- Critical Illness
- Being tested
- 10-min online survey
- Keywords
- Crystalloids, Colloids, Fluid resuscitation, Intensive care unit, Sepsis, Bleeding
- Medical subject headings
- Critical Illness, Sepsis, Hemorrhage
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
10-min online surveyOther
This is a cross-sectional study. The data are collected by a 10-min online survey administered to included physicians which will be distributed via online channels such as such as official website or Facebook pages of Society of intensive care or Society of nephrology of corresponding countries.
| Study group | Role | What they receive |
|---|---|---|
| Survey participants | Participants in this cross-sectional survey will be physicians with specialty in Anesthesiology, Surgery, Critical care medicine, Pulmonology, Nephrology, General Medicine currently working in Surgical or Medical ICU in Southeast Asia in year 2023-2024 Receives: Other: 10-min online survey |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fluid resuscitation practice pattern
Preferences for fluid resuscitation in 3 types of patients (1. Septic 2. bleeding but not septic 3. not bleeding and not septic) during resuscitation and optimization phase.
Measured: 1/9/23-1/9/24
Secondary outcomes (2)
Preferences for volume status indicators.
Preferences for volume status indicators and diagnostic tools
Measured: 1/9/23-1/9/24
Fluid resuscitation practice pattern in hypoalbuminemic state
Preferences for fluid resuscitation in the 3 types of patients with hypoalbuminemia including (1) cirrhosis (2) nephrotic syndrome (3) other significant hypoalbuminemia during resuscitation/optimization phase and stabilization phase
Measured: 1/9/23-1/9/24
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Sep 2023
- Study start31 Jan 2024
- Primary completion31 Jul 2025
- Study completion30 Sep 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Critical IllnessStudies of the same condition, open and under way.
- More trials run by Chulalongkorn UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 1,000 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chulalongkorn University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nattachai Srisawat ,M.D., Chulalongkorn University
- Investigators
- Nattachai Srisawat, MD, Principal investigator, Chulalongkorn University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06034990
- Sponsor's protocol ID
- IRB.457/66
- Acronym
- Fluid-SEA
- Status last verified
- Sep 2026
- First submitted
- 6 Sep 2023
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Miller TE, Bunke M, Nisbet P, Brudney CS. Fluid resuscitation practice patterns in intensive care units of the USA: a cross-sectional survey of critical care physicians. Perioper Med (Lond). 2016 Jun 16;5:15. doi: 10.1186/s13741-016-0035-2. eCollection 2016.
PubMed 27313844
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- ICU Fluid Utilization Survey in Southeast Asia
- ClinicalTrials.gov ID
- NCT06034990
- Acronym / sponsor ID
- Fluid-SEA / IRB.457/66
- Conditions
- Critical Illness
- Keywords
- Crystalloids, Colloids, Fluid resuscitation, Intensive care unit, Sepsis, Bleeding
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,000 participants (actual)
- Lead sponsor
- Chulalongkorn UniversityUniversity, hospital or other
- Study start
- 31 Jan 2024 (actual)
- Primary completion
- 31 Jul 2025 (actual)
- Study completion
- 30 Sep 2026 (actual)
- First posted
- 13 Sep 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume resuscitation (representing normal condition), (2) bleeding but not septic (representing normal vascular integrity but with a loss of intravascular colloids), (3) septic (representing the condition with increase vascular permeability and endothelium damage) in the ICU within Southeast Asia.
The data are collected by a 10-min online survey administered to included physicians which will be distributed via multiple online channels through representatives of each countries.
Detailed description
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume resuscitation (representing normal condition), (2) bleeding but not septic (representing normal vascular integrity but with a loss of intravascular colloids), (3) septic (representing the condition with increase vascular permeability and endothelium damage) in the ICU within Southeast Asia, and to determine whether co-morbidities with hypoalbuminemia, clinician specialties, hospital practice settings, geographic locations and re-imbursement limitation especially for colloids influence the practice patterns of fluid utilization in different phases in the 3 types of patients. Ultimately, the information provided by this study could also provide basic background information for the design of future clinical trials regarding fluid resuscitation strategies.
The data are collected by a 10-min online survey administered to included physicians which will be distributed via multiple online channels through representatives of each countries.
The survey will start with an inform-consent form prior to starting the survey questions which consist of 13-item questionnaire obtaining information on
- Demographics data of clinicians taking the survey on primary specialty, region or country of practice and hospital settings.
- Preferences for volume status indicators.
- Preferences for fluid resuscitation in 3 types of patients (1. Septic 2. bleeding but not septic 3. not bleeding and not septic) during resuscitation and optimization phase.
- Preferences for fluid resuscitation in the 3 types of patients with hypoalbuminemia including (1) cirrhosis (2) nephrotic syndrome (3) other significant hypoalbuminemia during resuscitation/optimization phase and stabilization phase
- The reasons for using colloids for volume expansion
- The experience of adverse reactions to albumin
- The awareness and importance of non-oncotic properties of albumin
- The impact of reimbursement for colloids on resuscitation fluid choice
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Survey participants | – | Other: 10-min online surveyParticipants in this cross-sectional survey will be physicians with specialty in Anesthesiology, Surgery, Critical care medicine, Pulmonology, Nephrology, General Medicine currently working in Surgical or Medical ICU in Southeast Asia in year 2023-2024 |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Physicians with specialty in Anesthesiology, Surgery, Critical care medicine, Pulmonology, Nephrology, General Medicine currently working in Surgical or Medical ICU in Southeast Asia in year 2023-2024
Key inclusion criteria (3 listed)
- Specialty must be in Anesthesiology, Surgery, Critical Care Medicine, Pulmonology, Nephrology, Internal Medicine, General Practitioner
- Practice must be in Southeast Asia hospitals
- Must work in Surgical ICU, Medical ICU , and/or Mixed ICU
Key exclusion criteria (1 listed)
- 1.Physicians who worked in cardiac, neurology or pediatric ICUs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 10-min online surveyThis is a cross-sectional study. The data are collected by a 10-min online survey administered to included physicians which will be distributed via online channels such as such as official website or Facebook pages of Society of intensive care or Society of nephrology of corresponding countries. | Other | Survey participants |
Primary outcome
Fluid resuscitation practice pattern
Time frame: 1/9/23-1/9/24
Preferences for fluid resuscitation in 3 types of patients (1. Septic 2. bleeding but not septic 3. not bleeding and not septic) during resuscitation and optimization phase.
2 secondary outcomes
Preferences for volume status indicators.
Time frame: 1/9/23-1/9/24
Fluid resuscitation practice pattern in hypoalbuminemic state
Time frame: 1/9/23-1/9/24
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Background: PubMed 27313844Miller TE, Bunke M, Nisbet P, Brudney CS. Fluid resuscitation practice patterns in intensive care units of the USA: a cross-sectional survey of critical care physicians. Perioper Med (Lond). 2016 Jun 16;5:15. doi: 10.1186/s13741-016-0035-2. eCollection 2016.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nattachai Srisawat, MD principal investigator
Chulalongkorn University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Critical Illness, run by Chulalongkorn University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fluid resuscitation practice pattern (time frame: 1/9/23-1/9/24). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06034990, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.