Multiple Sclerosis, MSNCT06839924
Effect of Motor Cognitive Interference on Cognition and Quality of Life on Patients with Multiple Sclerosis
A study testing Cognitive Motor Interference and traditional physical therapy in people with Multiple Sclerosis, MS, run by Cairo University at 1 site in Egypt.
Trial summary
Is there an effect of Cognitive Motor Interference on Cognition and quality of life on Multiple Sclerosis patients. Read more about this study
- Who is it for?
- Ages 25 to 45 years
- Conditions the study is for
- Multiple Sclerosis, MS
- What is being tested?
- Cognitive Motor Interference and traditional physical therapy
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Dec 2024to 1 Aug 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- M S patients complain of Mild Cognitive impairment according to Modified Mini Mental State (MMSE).
- Patients with remission and relapse, primary and secondary progression types of MS.
- Age between 25 and 45 years.
- Patients from both gender.
Who cannot join
- patients have visual disorders
- patients have auditory disturbance
- Non educational patients.
- Patients with psychiatric disorders.
- Patients with mod to severe cognitive impairment according to MMSE
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Motor Cognitive Interference on Cognition and Quality of Life on Multiple Sclerosis Patients
Is there an effect of Cognitive Motor Interference on Cognition and quality of life on Multiple Sclerosis patients.
Read the detailed description
we will assess the effectiveness of Cognitive Motor interference on Cognition and quality of life on Multiple Sclerosis patients
- Conditions
- Multiple Sclerosis, MS
- Being tested
- Cognitive Motor Interference, traditional physical therapy
- Keywords
- Multiple Sclerosis, MS, Cognition, Cognitive Motor Interference, quality of life, Qol
- Medical subject headings
- Multiple Sclerosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cognitive Motor InterferenceBehavioural
Dual task that uses cognitive in addition to Motor training
traditional physical therapyBehavioural
physiotherapy program including exercises in addition to physical modalities
| Study group | Role | What they receive |
|---|---|---|
| Study group | Experimental | Study group will uses Cognitive Motor Interference Receives: Behavioral: Cognitive Motor Interference |
| Control group will uses traditional physical therapy | Active comparator | control group will use traditional physiotherapy Receives: Behavioral: traditional physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cognition (working memory and divided attention)
cognition domains including working memory and divided attention will be assessed by rehacom V 6.10.2.0 software
Measured: baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks
Secondary outcomes (1)
A health-related quality of life
quality of life will be assessed by Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
Measured: Baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Feb 2025
- Study start10 Dec 2024
- Primary completion12 Jun 2025 (estimated)
- Study completion1 Aug 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Multiple Sclerosis, MSStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 44 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Abd El Aziz, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06839924
- Sponsor's protocol ID
- P.T>REC/012/005458
- Status last verified
- Feb 2025
- First submitted
- 16 Dec 2024
- Last updated
- 21 Feb 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Motor Cognitive Interference on Cognition and Quality of Life on Multiple Sclerosis Patients
- ClinicalTrials.gov ID
- NCT06839924
- Acronym / sponsor ID
- P.T>REC/012/005458
- Conditions
- Multiple Sclerosis, MS
- Keywords
- Multiple Sclerosis, MS, Cognition, Cognitive Motor Interference, quality of life, Qol
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 44 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Dec 2024 (actual)
- Primary completion
- 12 Jun 2025 (estimated)
- Study completion
- 1 Aug 2025 (estimated)
- First posted
- 21 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Is there an effect of Cognitive Motor Interference on Cognition and quality of life on Multiple Sclerosis patients.
Detailed description
we will assess the effectiveness of Cognitive Motor interference on Cognition and quality of life on Multiple Sclerosis patients
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Study group | Experimental | Behavioral: Cognitive Motor InterferenceStudy group will uses Cognitive Motor Interference |
| Control group will uses traditional physical therapy | Active comparator | Behavioral: traditional physical therapycontrol group will use traditional physiotherapy |
Who may qualify
- Ages
- 25 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- M S patients complain of Mild Cognitive impairment according to Modified Mini Mental State (MMSE).
- Patients with remission and relapse, primary and secondary progression types of MS.
- Age between 25 and 45 years.
- Patients from both gender.
Key exclusion criteria (5 listed)
- patients have visual disorders
- patients have auditory disturbance
- Non educational patients.
- Patients with psychiatric disorders.
- Patients with mod to severe cognitive impairment according to MMSE
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cognitive Motor InterferenceDual task that uses cognitive in addition to Motor training | Behavioural | Study group |
| traditional physical therapyphysiotherapy program including exercises in addition to physical modalities | Behavioural | Control group will uses traditional physical therapy |
Primary outcome
Cognition (working memory and divided attention)
Time frame: baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks
cognition domains including working memory and divided attention will be assessed by rehacom V 6.10.2.0 software
1 secondary outcome
A health-related quality of life
Time frame: Baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Feb 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cognitive Motor Interference and traditional physical therapy in people with Multiple Sclerosis, MS, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 21 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cognition (working memory and divided attention) (time frame: baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Feb 2025.