Coronary Artery BypassNCT06910020
Effect of the Active Cycle of Breathing Technique on Coronary Artery Bypass Graft Patients' Outcomes
A study testing Active Cycle of Breathing Technique in people with Coronary Artery Bypass and Coronary Arterial Disease (CAD), run by Mansoura University at 1 site in Egypt.
Trial summary
Following CABG surgery, patients are at risk for several complications. One of the most common complications is postoperative pulmonary complications, which include atelectasis and dyspnea. These complications cause prolonged ICU length of stay and increased health care costs. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Coronary Artery Bypass, Coronary Arterial Disease (CAD)
- What is being tested?
- Active Cycle of Breathing Technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 92 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Jan 2024to 25 May 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Any adult patient who will undergo CABG
Who cannot join
- Mechanically ventilated patients on the first postoperative day.
- Patients with preoperative lung collapse or pleural effusion.
Trial locations and contacts
1 site in 1 country.
About this study
Following CABG surgery, patients are at risk for several complications. One of the most common complications is postoperative pulmonary complications, which include atelectasis and dyspnea. These complications cause prolonged ICU length of stay and increased health care costs. Several studies recommended the active cycle of breathing technique as a method that increases secretion removal and improves lung functions, thus reducing the incidence of postoperative pulmonary complications. Our study aims to investigate the effect of the active cycle of breathing technique on coronary artery bypass graft patients' outcomes.
- Being tested
- Active Cycle of Breathing Technique
- Keywords
- CABG, ACBT, Postoperative Pulmonary Complications, Chest tube duration, Hemodynamic parameters, Chest expansion
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Active Cycle of Breathing TechniqueOther
- Patients will assume the sitting position and relax their shoulders, then perform the following:
- Breathing control (abdominal breathing)
- Chest expansion (thoracic breathing)
- Huff cough (forced expiratory technique)
- After completing the above actions, patients will be asked to cough up the residual deep sputum to promote pulmonary expansion.
- The ACBT intervention will be performed for three days, each day two sessions, each session three courses, with 10 minutes of rest between them as needed.
| Study group | Role | What they receive |
|---|---|---|
| Active Cycle of Breathing Technique | Experimental | Patients who will perform ACBT exercises in addition to the routine ICU care. Receives: Other: Active Cycle of Breathing Technique |
| Control Group | No intervention | Patients who will receive routine ICU care (chest physiotherapy and incentive spirometer) without ACBT. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Atelectasis
Atelectasis will be assessed using chest X-rays.
Measured: The first three postoperative days
Dyspnea
Dyspnea level will be assessed using the modified Borg scale.
Measured: The first three postoperative days
Functional capacity
Functional capacity will be assessed using the six-minute walk test
Measured: The first three postoperative days
Hemodynamic parameters
Hemodynamic parameters will include respiratory rate expressed as the number of cycles per minute, which will be assessed using the cardiac monitor
Measured: The first three postoperative days
Chest expansion
Chest expansion will be measured at three points (axillary, xiphoid point, and umbilical level) using a measuring tape in centimeters.
Measured: The first three postoperative days
Duration of chest tube
Duration of chest tube
Measured: Up to 1 week
Length of ICU stay
Measure the duration of the patient's ICU stay
Measured: For up to 1 week
Hemodynamic Parameters
Hemodynamic parameters will include oxygen saturation, which will be assessed using the pulse oximeter and will be expressed as a percentage %
Measured: For the first three postoperative days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Apr 2025
- Study start10 Jan 2024
- Primary completion20 Sep 2024
- Study completion25 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Coronary Artery BypassStudies of the same condition, open and under way.
- More trials run by Mansoura UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Outcomes assessor
- Enrolment
- 92 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mansoura University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shaimaa Nagi Abdelkader Yousef, Mansoura University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06910020
- Sponsor's protocol ID
- 320
- Other IDs
- 320
- Status last verified
- Mar 2025
- First submitted
- 18 Mar 2025
- Last updated
- 10 Jun 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 10 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of the Active Cycle of Breathing Technique on Coronary Artery Bypass Graft Patients' Outcomes
- ClinicalTrials.gov ID
- NCT06910020
- Acronym / sponsor ID
- 320
- Keywords
- CABG, ACBT, Postoperative Pulmonary Complications, Chest tube duration, Hemodynamic parameters, Chest expansion
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 92 participants (actual)
- Lead sponsor
- Mansoura UniversityUniversity, hospital or other
- Study start
- 10 Jan 2024 (actual)
- Primary completion
- 20 Sep 2024 (actual)
- Study completion
- 25 May 2025 (actual)
- First posted
- 4 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Following CABG surgery, patients are at risk for several complications. One of the most common complications is postoperative pulmonary complications, which include atelectasis and dyspnea. These complications cause prolonged ICU length of stay and increased health care costs. Several studies recommended the active cycle of breathing technique as a method that increases secretion removal and improves lung functions, thus reducing the incidence of postoperative pulmonary complications. Our study aims to investigate the effect of the active cycle of breathing technique on coronary artery bypass graft patients' outcomes.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Active Cycle of Breathing Technique | Experimental | Other: Active Cycle of Breathing TechniquePatients who will perform ACBT exercises in addition to the routine ICU care. |
| Control Group | No intervention | –Patients who will receive routine ICU care (chest physiotherapy and incentive spirometer) without ACBT. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Any adult patient who will undergo CABG
Key exclusion criteria (2 listed)
- Mechanically ventilated patients on the first postoperative day.
- Patients with preoperative lung collapse or pleural effusion.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Active Cycle of Breathing Technique* Patients will assume the sitting position and relax their shoulders, then perform the following: 1. Breathing control (abdominal breathing) 2. Chest expansion (thoracic breathing) 3. Huff cough (forced expiratory technique) * After completing the above actions, patients will be asked to cough up the residual deep sputum to promote pulmonary expansion. * The ACBT intervention will be performed for three days, each day two sessions, each session three courses, with 10 minutes of rest between them as needed. | Other | Active Cycle of Breathing Technique |
Primary outcome
Atelectasis
Time frame: The first three postoperative days
Atelectasis will be assessed using chest X-rays.
Dyspnea
Time frame: The first three postoperative days
Dyspnea level will be assessed using the modified Borg scale.
Functional capacity
Time frame: The first three postoperative days
Functional capacity will be assessed using the six-minute walk test
Hemodynamic parameters
Time frame: The first three postoperative days
Hemodynamic parameters will include respiratory rate expressed as the number of cycles per minute, which will be assessed using the cardiac monitor
Chest expansion
Time frame: The first three postoperative days
Chest expansion will be measured at three points (axillary, xiphoid point, and umbilical level) using a measuring tape in centimeters.
Duration of chest tube
Time frame: Up to 1 week
Duration of chest tube
Length of ICU stay
Time frame: For up to 1 week
Measure the duration of the patient's ICU stay
Hemodynamic Parameters
Time frame: For the first three postoperative days
Hemodynamic parameters will include oxygen saturation, which will be assessed using the pulse oximeter and will be expressed as a percentage %
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Jun 2025.
- Individual participant dataSharing planned: Undecided
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Coronary Artery Bypass Graft (CABG)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Active Cycle of Breathing Technique in people with Coronary Artery Bypass and Coronary Arterial Disease (CAD), run by Mansoura University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 10 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Atelectasis (time frame: The first three postoperative days). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Jun 2025.