Learning; Lack of (Specific)NCT07185763
Nano-Learning for Improving Compliance Among Older Adults With Sarcopenia
A study testing Nano-Learning interventional program in people with Learning; Lack of (Specific) and Depression, run by Alexandria University at 1 site in Egypt.
Trial summary
Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Read more about this study
- Who is it for?
- Ages 58 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Learning; Lack of (Specific), Depression, Older Adults
- What is being tested?
- Nano-Learning interventional program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 180 participants
- Where
- 1 siteEgypt
- Study dates
- 7 Sep 2025to 25 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 58 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Participants were eligible if they were 60 years or older,
- had a diagnosis of sarcopenia based on a cut-off score of ≥3 of the Sarcopenia Geriatric Scale (SARCO-GS) (Rosas-Carrasco, 2023),
- able to communicate effectively, and provided informed consent.
Who cannot join
- Exclusion criteria encompassed severe cognitive impairment, debilitating chronic conditions, or unstable medical status that could hinder participation.
- Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), with a cutoff score of 25 or below used to exclude participants (Nasreddine, 2005).
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Feasibility and Outcomes of Nano-Learning for Improving Compliance With Physical and Nutritional Guidelines and Reducing Late-Life Depression Among Older Adults With Sarcopenia in a Rural Province
Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.
Read the detailed description
Nanolearning is an innovative pedagogical strategy that delivers content in highly focused, ultra-short learning experiences, often lasting less than two minutes, aimed at teaching a single skill or topic . Typically offered digitally through bite-sized video lessons or interactive practice exercises, it capitalizes on learners' preference for short-form content and informal learning methods, making knowledge acquisition more accessible and manageable for busy individuals. A defining feature of nano-learning is its brevity, with lessons intentionally kept under two minutes to align with contemporary learning habits, such as engaging with short-form videos on platforms like YouTube Shorts and TikTok . Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.
- Conditions
- Learning; Lack of (Specific), Depression, Older Adults, Sarcopenia
- Being tested
- Nano-Learning interventional program
- Medical subject headings
- Depression, Sarcopenia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nano-Learning interventional programBehavioural
AI-based Nano-learning videos involves designing ultra-short, single-focus lessons (not exceeding 2 minutes). Each session was delivered in form of some videos.
| Study group | Role | What they receive |
|---|---|---|
| interventional group | Experimental | • Recruitment was conducted through face-to-face interviews in the clinic's waiting areas by the research team. These initial meetings, lasting approximately 20-30 minutes per participant, were essential for building rapport, obtaining anthropometric and other objective data, and ensuring informed consent. During the interview, the researchers explained the purpose and procedures of the study in detail, collected participants' mobile phone numbers, and administered the baseline (pretest) assessment using the study tools. Receives: Behavioral: Nano-Learning interventional program |
| control | No intervention | they will be exposed only to the routine care provided by the nursing homes. |
What is being measured
The primary outcome is the main question the study is designed to answer.
A Composite Physical Function (CPF) Scale
is a validated tool designed to assess functional capacity in older adults across a continuum of daily activities. It consists of 12 items organized hierarchically, beginning with two basic activities of daily living (BADL) related to self-care, eating, and hygiene, followed by eight instrumental activities of daily living (IADL) that assess community functioning such as household chores, shopping, and mobility, and concluded with two advanced activities involving more demanding household tasks and strenuous physical exercise.
Measured: 2 month
Secondary outcomes (2)
Mini Nutritional Assessment-Short Form (MNA-SF)
is a validated screening tool and one of the most widely recognized and well-studied tools for nutritional screening. It is designed to quickly identify older adults who are malnourished or at risk of malnutrition. As a shortened version of the full Mini Nutritional Assessment, it is widely used in clinical, community, and research settings due to its simplicity and time efficiency (Vellas et al., 2006).
Measured: 2 month
Geriatric Depression Scale-Short Form (GDS-SF)
is a 15-item self-report tool designed to evaluate depression and overall well-being in older adults. Respondents indicate how they have felt during the past week by choosing either "Yes" (scored as 1) or "No" (scored as 0). Scores are summed to yield a total ranging from 0 to 15, with 0-4 reflecting no depression, 5-8 indicating mild depression, 9-11 suggesting moderate depression, and 12-15 representing severe depression. In 2013, Elhusseini translated the scale into Arabic, confirming its validity and reliability (r = 0.70). The GDS-SF remains one of the most effective and widely used geriatric-specific screening instruments for detecting depression in older adults (Abd El Fatah et al., 2022; Stone et al., 2019).
Measured: 2 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Sep 2025
- Study start7 Sep 2025
- Primary completion20 Jan 2026 (estimated)
- Study completion25 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Learning; Lack of (Specific)Studies of the same condition, open and under way.
- More trials run by Alexandria UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 180 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Alexandria University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Rasha salah elsayed eweida, Alexandria University
- Investigators
- rasha eweida, Principal investigator, Damanhour University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07185763
- Sponsor's protocol ID
- 7/9/2025
- Status last verified
- Sep 2025
- First submitted
- 7 Sep 2025
- Last updated
- 22 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Feasibility and Outcomes of Nano-Learning for Improving Compliance With Physical and Nutritional Guidelines and Reducing Late-Life Depression Among Older Adults With Sarcopenia in a Rural Province
- ClinicalTrials.gov ID
- NCT07185763
- Acronym / sponsor ID
- 7/9/2025
- Conditions
- Learning; Lack of (Specific), Depression, Older Adults, Sarcopenia
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 180 participants (estimated)
- Lead sponsor
- Alexandria UniversityUniversity, hospital or other
- Study start
- 7 Sep 2025 (actual)
- Primary completion
- 20 Jan 2026 (estimated)
- Study completion
- 25 Feb 2026 (estimated)
- First posted
- 22 Sep 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.
Detailed description
Nanolearning is an innovative pedagogical strategy that delivers content in highly focused, ultra-short learning experiences, often lasting less than two minutes, aimed at teaching a single skill or topic . Typically offered digitally through bite-sized video lessons or interactive practice exercises, it capitalizes on learners' preference for short-form content and informal learning methods, making knowledge acquisition more accessible and manageable for busy individuals. A defining feature of nano-learning is its brevity, with lessons intentionally kept under two minutes to align with contemporary learning habits, such as engaging with short-form videos on platforms like YouTube Shorts and TikTok . Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.
Study design
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| interventional group | Experimental | Behavioral: Nano-Learning interventional program• Recruitment was conducted through face-to-face interviews in the clinic's waiting areas by the research team. These initial meetings, lasting approximately 20-30 minutes per participant, were essential for building rapport, obtaining anthropometric and other objective data, and ensuring informed consent. During the interview, the researchers explained the purpose and procedures of the study in detail, collected participants' mobile phone numbers, and administered the baseline (pretest) assessment using the study tools. |
| control | No intervention | –they will be exposed only to the routine care provided by the nursing homes. |
Who may qualify
- Ages
- 58 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Participants were eligible if they were 60 years or older,
- had a diagnosis of sarcopenia based on a cut-off score of ≥3 of the Sarcopenia Geriatric Scale (SARCO-GS) (Rosas-Carrasco, 2023),
- able to communicate effectively, and provided informed consent.
Key exclusion criteria (2 listed)
- Exclusion criteria encompassed severe cognitive impairment, debilitating chronic conditions, or unstable medical status that could hinder participation.
- Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), with a cutoff score of 25 or below used to exclude participants (Nasreddine, 2005).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nano-Learning interventional programAI-based Nano-learning videos involves designing ultra-short, single-focus lessons (not exceeding 2 minutes). Each session was delivered in form of some videos. | Behavioural | interventional group |
Primary outcome
A Composite Physical Function (CPF) Scale
Time frame: 2 month
is a validated tool designed to assess functional capacity in older adults across a continuum of daily activities. It consists of 12 items organized hierarchically, beginning with two basic activities of daily living (BADL) related to self-care, eating, and hygiene, followed by eight instrumental activities of daily living (IADL) that assess community functioning such as household chores, shopping, and mobility, and concluded with two advanced activities involving more demanding household tasks and strenuous physical exercise.
2 secondary outcomes
Mini Nutritional Assessment-Short Form (MNA-SF)
Time frame: 2 month
Geriatric Depression Scale-Short Form (GDS-SF)
Time frame: 2 month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2025.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
rasha eweida principal investigator
Damanhour University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nano-Learning interventional program in people with Learning; Lack of (Specific) and Depression, run by Alexandria University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 22 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
A Composite Physical Function (CPF) Scale (time frame: 2 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2025.