Patellofemoral PainNCT07266922
A Self-Directed Web-Based Education for Boston Marathon Runners With Patellofemoral Pain
A study testing Education Platform-MyKneeCap.com in people with Patellofemoral Pain, run by Boston Children's Hospital at 1 site in United States.
Trial summary
Runners experience diverse lower extremity injuries, and the most common is patellofemoral pain (PFP)-commonly known as "runner's knee" and characterized by pain around and/or behind the kneecap. Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Patellofemoral Pain
- What is being tested?
- Education Platform-MyKneeCap.com
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 104 participants
- Where
- 1 siteUnited States
- Study dates
- 20 Feb 2026to 1 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Insidious onset of peripatellar and/or retropatellar pain ≥3 months
- Worst pain level in the previous week ≥3/10 on the numeric pain rating scale
- Pain during at least two of the following tasks: prolonged sitting, kneeling, squatting, walking, running, jumping, and stair negotiation.
- All participants must have access to an internet-enabled device (e.g., computer, tablet, smartphone) equipped with audio capabilities sufficient to engage with the web-based education platform
Who cannot join
- History of lower extremity surgery
- History of lower extremity pain or injury (other than patellofemoral pain) in the previous six months
- History of patellar dislocation or subluxation
- Internal derangement (e.g., meniscal lesion)
- Ligamentous instability
- Other sources of anterior knee pain (e.g., patellar tendinopathy, bursitis)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Boston Children's Hospital
Waltham, Massachusetts, 02453
About this study
Official title: Running Informed, Not Just Trained: A Self-Directed Web-Based Education for Boston Marathon Runners With Patellofemoral Pain
Runners experience diverse lower extremity injuries, and the most common is patellofemoral pain (PFP)-commonly known as "runner's knee" and characterized by pain around and/or behind the kneecap. The aim of this study is to evaluate the effectiveness of a 6-week, self-directed, web-based education program for runners competing in the 2026 Boston Marathon. The study will evaluate outcomes, including pain, function, and marathon performance, in runners who use a web-based educational program designed to help them understand and manage knee pain. There will be two groups: Group 1 will receive the 6-week web-based educational program prior to the 2026 Boston Marathon, while Group 2 will serve as the wait-and-see control group (no intervention) prior to the marathon and then receive the same program 6 weeks after completing the marathon.
- Conditions
- Patellofemoral Pain
- Being tested
- Education Platform-MyKneeCap.com
- Keywords
- Anterior knee pain, Patient education
- Medical subject headings
- Patellofemoral Pain Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Education Platform-MyKneeCap.comBehavioural
This intervention uses MyKneeCap.com, a free, web-based educational platform designed to help runners understand their knee pain. The platform provides information about patellofemoral pain and includes exercise programs aimed at reducing pain and improving knee function. This intervention does not involve any drugs, devices, or other procedural components.
| Study group | Role | What they receive |
|---|---|---|
| Pre-Marathon Education | Experimental | This group will receive the educational platform for 6 weeks prior to the 2026 Boston Marathon. Participants will have access to MyKneeCap.com, a web-based platform designed to provide runners with evidence-based education on the physical and non-physical factors contributing to patellofemoral pain, as well as strategies for self-managing symptoms tailored specifically for runners. Receives: Behavioral: Education Platform-MyKneeCap.com |
| Wait-and-See Control / Post-Marathon Education | Other | This group will serve as a wait-and-see control (no intervention) prior to the 2026 Boston Marathon. After completing the marathon, participants will receive access to MyKneeCap.com, a web-based platform designed to provide runners with evidence-based education on the physical and non-physical factors contributing to patellofemoral pain, as well as strategies for self-managing symptoms tailored specifically for runners. Receives: Behavioral: Education Platform-MyKneeCap.com |
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinical outcomes (pain)
Pain will be assessed for current pain and worst pain in the previous week using a 10-cm visual analog scale (VAS; 0=no pain; 10=worst pain imaginable), a reliable, valid, and responsive tool for evaluating treatment outcomes for patellofemoral pain.
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Clinical outcomes (self-reported function)
Self-reported function will be evaluated using the 11-item Knee Injury and Osteoarthritis Outcome Score-Patellofemoral subscale (KOOS-PF; 0=extreme disability; 100=no disability), a reliable tool with the highest content validity for patellofemoral pain.
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Clinical outcomes (global rating of change)
Global rating of change will be assessed for perceived recovery using a 7-point Likert scale (much worse, worse, slightly worse, no change, slightly better, better, or much better). The global rating of change scale is a reliable, clinically relevant, and patient-centered measure for interpreting meaningful improvements.
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Secondary outcomes (11)
Psychological function (fear-avoidance beliefs)
Fear-avoidance beliefs will be quantified using the 5-item Fear-Avoidance Beliefs Questionnaire-Physical Activity subscale (FABQ-PA; 0=no fear-avoidance; 24=extreme fear-avoidance). The FABQ-PA is a reliable and valid tool and represents a key psychological profile in patellofemoral pain management.
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Psychological function (pain self-efficacy)
Pain self-efficacy will be quantified using the 10-item Pain Self-Efficacy Questionnaire (PSEQ; 0=no self-efficacy; 60=extreme self-efficacy). The PSEQ is a reliable and valid tool and represents a key psychological profile in patellofemoral pain management.
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Patient satisfaction
Satisfaction during the preceding six weeks of marathon training will be rated on a 5-point Likert scale (very dissatisfied, somewhat dissatisfied, neither, somewhat satisfied, or very satisfied).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Marathon performance (finish time)
Finish time will be evaluated by comparing the official finish time to the participant's intended finish time (in minutes).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Marathon performance (division ranking)
Division ranking will be evaluated by comparing the division ranking to the participant's intended division ranking (in rank).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Medical service use
Intra-event medical encounters for knee pain will be self-recorded (in count).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Secondary musculoskeletal complaints
Lower extremity pain or injuries (other than patellofemoral pain) sustained during the race will be self-recorded (in count).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Return to running readiness
Perceived readiness to return to competitive running will be assessed on a 5-point Likert scale (not at all, slightly, moderately, very, or extremely).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Barriers and facilitators (confidence in self-management)
Confidence in self-management ("I am confident in my ability to manage my symptoms and treatment plan on my own") will be measured using a 5-point Likert scale (strongly disagree, disagree, neither, agree, strongly agree).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Barriers and facilitators (usability of the education platform)
Usability of the education platform ("The web-based education platform is easy to use and navigate") will be measured using a 5-point Likert scale (strongly disagree, disagree, neither, agree, strongly agree).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Barriers and facilitators (treatment expectations)
Treatment expectations ("I believe that the web-based education and exercise program will help improve my condition") will be measured using a 5-point Likert scale (strongly disagree, disagree, neither, agree, strongly agree).
Measured: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Dec 2025
- Study start20 Feb 2026
- Primary completion1 Jun 2026 (estimated)
- Study completion1 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (46)Papers the sponsor has linked to this study.
- Other trials for Patellofemoral PainStudies of the same condition, open and under way.
- More trials run by Boston Children's HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- We will conduct a two-arm, parallel-group, single-blinded randomized controlled trial to evaluate the effect of the intervention prior to the marathon (Group 1: treatment vs. Group 2: wait-and-see control). After the marathon, Group 2 will receive the same intervention, and outcomes will be assessed in a quasi-experimental pre-post design (i.e., as a single treatment group).
- Masking
- None (open label)
- Enrolment
- 104 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Boston Children's Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sungwan Kim, Boston Children's Hospital
- Investigators
- Sungwan Kim, PhD, Principal investigator, Boston Children's Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07266922
- Sponsor's protocol ID
- IRB-P00052732
- Status last verified
- Mar 2026
- First submitted
- 19 Nov 2025
- Last updated
- 10 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: All IPD that will be shared will be de-identified and for manuscript and publishing purposes only. PHI data will not be accessible outside of the research team, and only de-identified data will be a part of the manuscript.
Publications
Piva SR, Gil AB, Moore CG, Fitzgerald GK. Responsiveness of the activities of daily living scale of the knee outcome survey and numeric pain rating scale in patients with patellofemoral pain. J Rehabil Med. 2009 Feb;41(3):129-35. doi: 10.2340/16501977-0295.
PubMed 19229444Evans JD. Straightforward statistics for the behavioral sciences. Thomson Brooks/Cole Publishing Co; 1996
Cohen J. Statistical power analysis for the behavioral sciences. Academic press; 1988
McKay AKA, Stellingwerff T, Smith ES, Martin DT, Mujika I, Goosey-Tolfrey VL, Sheppard J, Burke LM. Defining Training and Performance Caliber: A Participant Classification Framework. Int J Sports Physiol Perform. 2022 Feb 1;17(2):317-331. doi: 10.1123/ijspp.2021-0451. Epub 2022 Dec 29.
PubMed 34965513Briggs KK, Lysholm J, Tegner Y, Rodkey WG, Kocher MS, Steadman JR. The reliability, validity, and responsiveness of the Lysholm score and Tegner activity scale for anterior cruciate ligament injuries of the knee: 25 years later. Am J Sports Med. 2009 May;37(5):890-7. doi: 10.1177/0363546508330143. Epub 2009 Mar 4.
PubMed 19261899Vicenzino BT, Rathleff MS, Holden S, Maclachlan L, Smith BE, de Oliveira Silva D, van Middelkoop M. Developing Clinical and Research Priorities for Pain and Psychological Features in People With Patellofemoral Pain: An International Consensus Process With Health Care Professionals. J Orthop Sports Phys Ther. 2022 Jan;52(1):29-39. doi: 10.2519/jospt.2022.10647.
PubMed 34972490Asghari A, Nicholas MK. Pain self-efficacy beliefs and pain behaviour. A prospective study. Pain. 2001 Oct;94(1):85-100. doi: 10.1016/S0304-3959(01)00344-X.
PubMed 11576748Piva SR, Fitzgerald GK, Irrgang JJ, Fritz JM, Wisniewski S, McGinty GT, Childs JD, Domenech MA, Jones S, Delitto A. Associates of physical function and pain in patients with patellofemoral pain syndrome. Arch Phys Med Rehabil. 2009 Feb;90(2):285-95. doi: 10.1016/j.apmr.2008.08.214.
PubMed 19236982Nicholas MK. The pain self-efficacy questionnaire: Taking pain into account. Eur J Pain. 2007 Feb;11(2):153-63. doi: 10.1016/j.ejpain.2005.12.008. Epub 2006 Jan 30.
PubMed 16446108Waddell G, Newton M, Henderson I, Somerville D, Main CJ. A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain. 1993 Feb;52(2):157-168. doi: 10.1016/0304-3959(93)90127-B.
PubMed 8455963Kamper SJ, Maher CG, Mackay G. Global rating of change scales: a review of strengths and weaknesses and considerations for design. J Man Manip Ther. 2009;17(3):163-70. doi: 10.1179/jmt.2009.17.3.163.
PubMed 20046623Crossley KM, Macri EM, Cowan SM, Collins NJ, Roos EM. The patellofemoral pain and osteoarthritis subscale of the KOOS (KOOS-PF): development and validation using the COSMIN checklist. Br J Sports Med. 2018 Sep;52(17):1130-1136. doi: 10.1136/bjsports-2016-096776. Epub 2017 Mar 3.
PubMed 28258176Crossley KM, Bennell KL, Cowan SM, Green S. Analysis of outcome measures for persons with patellofemoral pain: which are reliable and valid? Arch Phys Med Rehabil. 2004 May;85(5):815-22. doi: 10.1016/s0003-9993(03)00613-0.
PubMed 15129407Souto LR, Pazzinatto MF, De Oliveira Silva D, Ezzat AM, Barton CJ. Self-directed versus supervised exercise therapy program combined with digitally supported patient education for knee osteoarthritis: a randomised, parallel-group feasibility trial. Semin Arthritis Rheum. 2025 Oct;74:152787. doi: 10.1016/j.semarthrit.2025.152787. Epub 2025 Jul 20.
PubMed 40716116Barton CJ, de Oliveira Silva D, Patterson BE, Crossley KM, Pizzari T, Nunes GS. A proximal progressive resistance training program targeting strength and power is feasible in people with patellofemoral pain. Phys Ther Sport. 2019 Jul;38:59-65. doi: 10.1016/j.ptsp.2019.04.010. Epub 2019 May 2.
PubMed 31055059
Study at a glance
From the registry record, last updated by the sponsor on 10 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Running Informed, Not Just Trained: A Self-Directed Web-Based Education for Boston Marathon Runners With Patellofemoral Pain
- ClinicalTrials.gov ID
- NCT07266922
- Acronym / sponsor ID
- IRB-P00052732
- Conditions
- Patellofemoral Pain
- Keywords
- Anterior knee pain, Patient education
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 104 participants (estimated)
- Lead sponsor
- Boston Children's HospitalUniversity, hospital or other
- Study start
- 20 Feb 2026 (actual)
- Primary completion
- 1 Jun 2026 (estimated)
- Study completion
- 1 Jul 2026 (estimated)
- First posted
- 5 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Runners experience diverse lower extremity injuries, and the most common is patellofemoral pain (PFP)-commonly known as "runner's knee" and characterized by pain around and/or behind the kneecap. The aim of this study is to evaluate the effectiveness of a 6-week, self-directed, web-based education program for runners competing in the 2026 Boston Marathon. The study will evaluate outcomes, including pain, function, and marathon performance, in runners who use a web-based educational program designed to help them understand and manage knee pain. There will be two groups: Group 1 will receive the 6-week web-based educational program prior to the 2026 Boston Marathon, while Group 2 will serve as the wait-and-see control group (no intervention) prior to the marathon and then receive the same program 6 weeks after completing the marathon.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- We will conduct a two-arm, parallel-group, single-blinded randomized controlled trial to evaluate the effect of the intervention prior to the marathon (Group 1: treatment vs. Group 2: wait-and-see control). After the marathon, Group 2 will receive the same intervention, and outcomes will be assessed in a quasi-experimental pre-post design (i.e., as a single treatment group).
| Arm | Type | Receives |
|---|---|---|
| Pre-Marathon Education | Experimental | Behavioral: Education Platform-MyKneeCap.comThis group will receive the educational platform for 6 weeks prior to the 2026 Boston Marathon. Participants will have access to MyKneeCap.com, a web-based platform designed to provide runners with evidence-based education on the physical and non-physical factors contributing to patellofemoral pain, as well as strategies for self-managing symptoms tailored specifically for runners. |
| Wait-and-See Control / Post-Marathon Education | Other | Behavioral: Education Platform-MyKneeCap.comThis group will serve as a wait-and-see control (no intervention) prior to the 2026 Boston Marathon. After completing the marathon, participants will receive access to MyKneeCap.com, a web-based platform designed to provide runners with evidence-based education on the physical and non-physical factors contributing to patellofemoral pain, as well as strategies for self-managing symptoms tailored specifically for runners. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Insidious onset of peripatellar and/or retropatellar pain ≥3 months
- Worst pain level in the previous week ≥3/10 on the numeric pain rating scale
- Pain during at least two of the following tasks: prolonged sitting, kneeling, squatting, walking, running, jumping, and stair negotiation.
- All participants must have access to an internet-enabled device (e.g., computer, tablet, smartphone) equipped with audio capabilities sufficient to engage with the web-based education platform
Key exclusion criteria (6 listed)
- History of lower extremity surgery
- History of lower extremity pain or injury (other than patellofemoral pain) in the previous six months
- History of patellar dislocation or subluxation
- Internal derangement (e.g., meniscal lesion)
- Ligamentous instability
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Education Platform-MyKneeCap.comThis intervention uses MyKneeCap.com, a free, web-based educational platform designed to help runners understand their knee pain. The platform provides information about patellofemoral pain and includes exercise programs aimed at reducing pain and improving knee function. This intervention does not involve any drugs, devices, or other procedural components. | Behavioural | Pre-Marathon Education, Wait-and-See Control / Post-Marathon Education |
Primary outcome
Clinical outcomes (pain)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Pain will be assessed for current pain and worst pain in the previous week using a 10-cm visual analog scale (VAS; 0=no pain; 10=worst pain imaginable), a reliable, valid, and responsive tool for evaluating treatment outcomes for patellofemoral pain.
Clinical outcomes (self-reported function)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Self-reported function will be evaluated using the 11-item Knee Injury and Osteoarthritis Outcome Score-Patellofemoral subscale (KOOS-PF; 0=extreme disability; 100=no disability), a reliable tool with the highest content validity for patellofemoral pain.
Clinical outcomes (global rating of change)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Global rating of change will be assessed for perceived recovery using a 7-point Likert scale (much worse, worse, slightly worse, no change, slightly better, better, or much better). The global rating of change scale is a reliable, clinically relevant, and patient-centered measure for interpreting meaningful improvements.
11 secondary outcomes
Psychological function (fear-avoidance beliefs)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Psychological function (pain self-efficacy)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Patient satisfaction
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Marathon performance (finish time)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Marathon performance (division ranking)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Medical service use
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Secondary musculoskeletal complaints
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Return to running readiness
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Barriers and facilitators (confidence in self-management)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Barriers and facilitators (usability of the education platform)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Barriers and facilitators (treatment expectations)
Time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Mar 2026.
- Background: PubMed 19229444Piva SR, Gil AB, Moore CG, Fitzgerald GK. Responsiveness of the activities of daily living scale of the knee outcome survey and numeric pain rating scale in patients with patellofemoral pain. J Rehabil Med. 2009 Feb;41(3):129-35. doi: 10.2340/16501977-0295.
- BackgroundEvans JD. Straightforward statistics for the behavioral sciences. Thomson Brooks/Cole Publishing Co; 1996
- BackgroundCohen J. Statistical power analysis for the behavioral sciences. Academic press; 1988
- Background: PubMed 34965513McKay AKA, Stellingwerff T, Smith ES, Martin DT, Mujika I, Goosey-Tolfrey VL, Sheppard J, Burke LM. Defining Training and Performance Caliber: A Participant Classification Framework. Int J Sports Physiol Perform. 2022 Feb 1;17(2):317-331. doi: 10.1123/ijspp.2021-0451. Epub 2022 Dec 29.
- Background: PubMed 19261899Briggs KK, Lysholm J, Tegner Y, Rodkey WG, Kocher MS, Steadman JR. The reliability, validity, and responsiveness of the Lysholm score and Tegner activity scale for anterior cruciate ligament injuries of the knee: 25 years later. Am J Sports Med. 2009 May;37(5):890-7. doi: 10.1177/0363546508330143. Epub 2009 Mar 4.
- Background: PubMed 34972490Vicenzino BT, Rathleff MS, Holden S, Maclachlan L, Smith BE, de Oliveira Silva D, van Middelkoop M. Developing Clinical and Research Priorities for Pain and Psychological Features in People With Patellofemoral Pain: An International Consensus Process With Health Care Professionals. J Orthop Sports Phys Ther. 2022 Jan;52(1):29-39. doi: 10.2519/jospt.2022.10647.
- Background: PubMed 11576748Asghari A, Nicholas MK. Pain self-efficacy beliefs and pain behaviour. A prospective study. Pain. 2001 Oct;94(1):85-100. doi: 10.1016/S0304-3959(01)00344-X.
- Background: PubMed 19236982Piva SR, Fitzgerald GK, Irrgang JJ, Fritz JM, Wisniewski S, McGinty GT, Childs JD, Domenech MA, Jones S, Delitto A. Associates of physical function and pain in patients with patellofemoral pain syndrome. Arch Phys Med Rehabil. 2009 Feb;90(2):285-95. doi: 10.1016/j.apmr.2008.08.214.
- Background: PubMed 16446108Nicholas MK. The pain self-efficacy questionnaire: Taking pain into account. Eur J Pain. 2007 Feb;11(2):153-63. doi: 10.1016/j.ejpain.2005.12.008. Epub 2006 Jan 30.
- Background: PubMed 8455963Waddell G, Newton M, Henderson I, Somerville D, Main CJ. A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain. 1993 Feb;52(2):157-168. doi: 10.1016/0304-3959(93)90127-B.
- Background: PubMed 20046623Kamper SJ, Maher CG, Mackay G. Global rating of change scales: a review of strengths and weaknesses and considerations for design. J Man Manip Ther. 2009;17(3):163-70. doi: 10.1179/jmt.2009.17.3.163.
- Background: PubMed 28258176Crossley KM, Macri EM, Cowan SM, Collins NJ, Roos EM. The patellofemoral pain and osteoarthritis subscale of the KOOS (KOOS-PF): development and validation using the COSMIN checklist. Br J Sports Med. 2018 Sep;52(17):1130-1136. doi: 10.1136/bjsports-2016-096776. Epub 2017 Mar 3.
- Individual participant dataSharing planned: Yes. All IPD that will be shared will be de-identified and for manuscript and publishing purposes only. PHI data will not be accessible outside of the research team, and only de-identified data will be a part of the manuscript.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sungwan Kim, PhD principal investigator
Boston Children's Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Education Platform-MyKneeCap.com in people with Patellofemoral Pain, run by Boston Children's Hospital at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 10 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinical outcomes (pain) (time frame: 6-weeks leading up to the Boston Marathon, or 6-weeks post completion of Boston Marathon). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07266922, which also lists 46 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Mar 2026; AzTrials last refreshed its copy on 27 Oct 2026.