Subthreshold DepressionNCT07275034
Effects of Virtual Reality-Based Horticultural Intervention for Older Adults With Subthreshold Depression in Nursing Homes
A study testing Virtual Reality-Based Horticultural Intervention System and routine health management in people with Subthreshold Depression, run by Fujian Medical University at 1 site in China.
Trial summary
Subthreshold depression represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing clinical depression and a critical phase for alleviating depressive symptoms. Read more about this study
- Who is it for?
- Ages 60 years and olderHealthy volunteers can take part
- Conditions the study is for
- Subthreshold Depression
- What is being tested?
- Virtual Reality-Based Horticultural Intervention System and routine health management
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 62 participants
- Where
- 1 siteChina
- Study dates
- 10 Nov 2025to 16 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- age ≥ 60 years;
- meeting the diagnostic threshold for StD27, defined as a score ≥ 16 on the Center for Epidemiologic Studies Depression Scale (CES-D);
- adequate visual, auditory, and verbal communication capacity;
- provision of written informed consent.
Who cannot join
- recent exposure to major traumatic events or current suicide risk;
- concurrent participation in other similar studies;
- not currently undergoing psychotherapy;
- current use of antidepressant pharmacotherapy;
- absence of severe cognitive impairment with a Montreal Cognitive Assessment (MoCA) score of >10;
- severe physical comorbidities with a Activity of daily living (ADL) score of >29 ;
- organic disorders resulting in functional self-care deficits.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Virtual Reality-Based Horticultural Intervention for Older Adults With Subthreshold Depression in Nursing Homes: Randomized Controlled Trial
Subthreshold depression represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing clinical depression and a critical phase for alleviating depressive symptoms. However, current research predominantly focuses on treating depression in the elderly, with insufficient attention to interventions for high-risk populations or limited to cross-sectional investigations of subthreshold depression risk factors. Therefore, prioritizing subthreshold depression in the elderly and implementing early interventions is essential. A 2024 article in The Lancet suggests that subthreshold depression treatment should prioritize psychotherapy and lifestyle adjustments over medication. Horticultural therapy, an interdisciplinary approach integrating horticulture, medicine, and psychology, demonstrates unique advantages over traditional medical treatments. In practical application, however, limited resources may hinder adequate support for horticultural activities, compromising activity quality, reducing therapeutic efficacy, and restricting the widespread adoption of horticultural therapy. Integrating VR technology with horticultural therapy can provide patients with more comprehensive, personalized, and effective mental health treatment plans, empowering them toward healthier, more positive lives. Therefore, the research team designed a VR horticultural intervention system for elderly individuals with subthreshold depression based on the Social Participation Competence Framework.
Read the detailed description
Subthreshold depression (SD) represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing major depressive disorder and a critical window for alleviating depressive symptoms. An editorial published in JAMA emphasized that research on subthreshold depression holds significant implications for exploring the prevention and treatment of depression. Therefore, prioritizing subthreshold depression in older adults and implementing early interventions is essential. Global population aging has made mental health disorders a major public health issue. The World Health Organization reports that about 7% of people aged 60 and above worldwide suffer from depression; in China, the rates are 19.05% for mild and 12.17% for moderate-to-severe depressive symptoms. Subthreshold depression (StD) is defined as having at least two depressive symptoms (e.g., anhedonia, loss of interest) for over two weeks without meeting major depressive disorder criteria. Among older adults, StD prevalence is about 18.6%, with a 12%-15.83% risk of progressing to major depression within 2-3 years. Thus, StD represents a critical window for early prevention, and timely non-pharmacological interventions are vital to reverse progression and reduce family and social care burdens.
Virtual Reality (VR) technology, as a novel intervention method, possesses three key characteristics: immersion, interactivity, and simulation. By replicating real-world settings such as home and community environments, it enriches the training experience for elderly individuals with depression, helping them adapt to diverse social contexts and enhancing intervention outcomes. Horticultural therapy, an interdisciplinary approach integrating horticulture, medicine, and psychology, offers relatively low treatment costs with minimal side effects. It plays a positive role in promoting physical recovery, improving emotional well-being, and enhancing social skills. Increasingly, research teams are exploring VR-generated virtual horticultural environments and horticultural activity interventions. VR technology addresses multiple limitations of traditional horticultural therapy. VR-based gardening activities overcome temporal and spatial constraints, reduce the costs and risks associated with physical gardening, and provide richer, more personalized socialized horticultural settings and activities that cater to diverse patient needs. Therefore, integrating VR technology with horticultural therapy offers patients a more comprehensive, personalized, and effective mental health treatment plan, empowering them to lead healthier, more positive lives.
- Conditions
- Subthreshold Depression
- Being tested
- Virtual Reality-Based Horticultural Intervention System, routine health management
- Keywords
- older adults, Subthreshold Depression, virutal reality, Gardening
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtual Reality-Based Horticultural Intervention SystemOther
The system comprised six progressive horticultural tasks, each associated with a distinct plant: (1) Tomato Planting, (2) Corn Cultivation, (3) Strawberry Care, (4) Eggplant Harvest, (5) Rose Growing, and (6) Sunflower Expansion. All tasks followed the same eight standardized steps-land preparation, seed sowing, seedling fertilization, initial watering, secondary fertilization, secondary watering, pest removal, and harvesting-but were arranged in a clear gradient of increasing difficulty. This progression was reflected in expanding planting scales, escalating task complexity, heightened cognitive load, more refined judgment requirements, and varying demands on operational precision. Each task was performed individually by the participant using the VR headset, without any multiplayer or collaborative components, as the system was designed for personalized, self-paced intervention.
routine health managementOther
This arm of seniors maintains their daily routines and participates regularly in the nursing home's daily activities.
| Study group | Role | What they receive |
|---|---|---|
| Virtual Reality Intervention | Experimental | This group utilized a virtual reality intervention system based on horticultural planting, designed and developed by the research team. Receives: Other: Virtual Reality-Based Horticultural Intervention System; Other: routine health management |
| Routine Care | Experimental | The control group received routine health management over the 6-week period, which encompassed assistance with daily living activities, basic medical care (including regular health check-ups and medication management), recreational activities, and environmental cleaning, with no additional structured intervention. Receives: Other: routine health management |
What is being measured
The primary outcome is the main question the study is designed to answer.
Subthreshold Depression
The Center for Epidemiological Surveys Depression Scale (CES-D) was developed by Rirodiff at the National Institute of Mental Health in the United States. It is designed for screening depressive symptoms in older adults, comprising 20 items. Each question assesses one symptom, covering 20 distinct symptoms in total. The total score ranges from 0 to 60 points. A score ≤15 indicates no depressive symptoms, 16-19 suggests possible depressive symptoms, and ≥20 confirms depressive symptoms. The Cronbach's alpha coefficient for the Chinese population is 0.90. It is one of the most commonly used subthreshold depression epidemiological survey tools, with existing studies defining CES-D ≥16 as subthreshold depression.
Translated with DeepL.com (free version)
Measured: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks .
Secondary outcomes (7)
General cognitive function
The Montreal Coanitive Asessment Scale,developed by Nasreddine in 2004 to assess participants'general cognitive function, covers eight areasof cognitive assessment, including visuospatial and executive function, naming, memory, attention, speech, abstraction, delayed recall, andorientation. The Changsha version of the Montreal Cognitive Assessment Scale was used in this study, and its Cronbach's a coeficient was 0.846,retest reliability was 0.974, and investigator reliability was 0.969. The score of the Montreal Cognitive Assessment Scale ranges from 0 to 30points. The higher the score,the better the cognitive function ofthe study subjects. The iliterate group s13, the primary school group s19 and thejunior high school and above group s24 can be judged as impaired cognitive function to correct the bias caused by education level.
Measured: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately.
Anxiety Condition
The self-rating anxiety scale (SAS) was designed and developed by Zung in the United States in 1971 to assess the severity of anxiety symptoms in individuals. It demonstrates good reliability and validity, with a split-half reliability coefficient of 0.696, test-retest reliability of 0.777, and internal consistency of 0.82. Additionally, it exhibits good construct validity . The scale comprises 20 items, with items 5, 9, 13, 17, and 19 scored in reverse. The scale employs a 1-4 rating scale (1 = never or rarely; 2 = a small portion of the time; 3 = a considerable portion of the time; 4 = most or all of the time). Individuals complete the scale based on their experiences during the past week. The total score is multiplied by 1.25, rounded to the nearest whole number to obtain a standardized score, which serves as the statistical indicator. A higher standardized score indicates more severe anxiety levels
Measured: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately
Self-Efficacy
The General Self-Efficacy Scale (GSES), developed by Schwarzer et al , was used. It consists of 10 items rated on a 4-point Likert scale, ranging from 1 (strongly disagree) to 4 (strongly agree). Higher total scores indicate higher levels of self-efficacy. In this study, the Cronbach α coefficient was 0.81.
Measured: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately.
Sleep Quality
This study employed the Pittsburgh Sleep Quality Index (PSQI) developed by Buysse et al. in 1989 to assess patients' sleep quality over the preceding month. The 19-item questionnaire comprises seven components: subjective sleep quality, sleep onset latency, sleep duration, sleep efficiency, sleep disturbances, hypnotic medication use, and daytime functioning. The total score ranges from 0 to 21, with higher scores indicating poorer sleep quality. The Cronbach's alpha coefficient for this scale is 0.85.
Measured: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately.
System Usability
System Usability Scale (SUS) Developed by Brooke et al., the scale used in this study is the Chinese version of the System Usability Scale translated and revised by Chinese scholars including Li Yongfeng. This scale is unidimensional and consists of 10 items. It employs a 5-point Likert scale, with scores ranging from 1 ("Strongly Disagree") to 5 ("Strongly Agree"). Positive items (Items 1, 3, 5, 7, 9) are scored positively: Actual item score = Item rating - 1. Negative items (Items 2, 4, 6, 8, 10) are scored negatively: Actual item score = 5 - Item rating. If an item is left blank, it is assigned a score of 3. The total scale score = sum of all item scores × 2.5. The scale has a maximum score of 100 points, with scores >60 considered usable, 70 considered good, ≥80 considered excellent, and ≥90 considered outstanding. The Cronbach's alpha coefficient for this scale is 0.91.
Measured: The intervention will be implemented in November 2025, with the evaluation conducted after the 6-week intervention period concludes.
Simulator Sickness
The Simulator Sickness Questionnaire(SSQ) developed by Kennedy et al. in 1993, is a widely used tool for assessing the subjective severity of simulator sickness symptoms. The SSQ consists of pre- and post-experiment sections. The pre-experiment section employs the Pensacola Motion Sickness Questionnaire (MSQ) to gather information about participants' current physical condition and prior simulator experience. The post-experiment section measures symptom severity on a four-point scale (0-3) for each symptom. SSQ items can be grouped into three factors: nausea (e.g., sweating, difficulty concentrating, gastric awareness), eye movement disturbances (e.g., headache, eye fatigue, blurred vision), and disorientation (e.g., head fullness, dizziness with eyes open/closed, vertigo). The SSQ can be scored in two ways: (1) Calculate the score for each factor by summing the scores of all relevant items (each factor includes 7 items), with a score range of 0-179.5
Measured: The intervention will be implemented in November 2025, with the evaluation conducted after the 6-week intervention period concludes.
Immersion Presence
The Immersion Presence Questionnaire (IPQ) was employed to evaluate users' sense of immersion in the experience. Developed by Schubert et al., this questionnaire was subsequently translated into Chinese and validated for reliability and validity by Liang Jiahui et al. The results demonstrated its strong reliability and validity, with a Cronbach's α coefficient of 0.82. The Chinese version comprises 13 items organized into three dimensions: spatial presence (Items 2, 3, 9), involvement (Items 1, 6, 10), and realism (Items 4, 5, 8, 11, 12, 13). Item 7 reflects overall presence. Each item employs a 7-point Likert scale ranging from -3 to 3 points, with items 10 and 12 reverse-scored. The total score ranges from -39 to 39 points, where a higher score indicates a better sense of presence experience in the virtual reality environment.
Item 7 reflects overall presence. Each item uses a 7-point Likert scale ranging from -3 to 3 points, with items 10 and 12 reverse-scored. The total score rang
Measured: The intervention will be implemented in November 2025, with the evaluation conducted after the 6-week intervention period concludes.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Dec 2025
- Study start10 Nov 2025
- Primary completion16 Jan 2026
- Study completion16 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Subthreshold DepressionStudies of the same condition, open and under way.
- More trials run by Fujian Medical UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 62 participants (actual)
Sponsor and investigators
- Lead sponsor
- Fujian Medical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zhu Ziping, Fujian Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07275034
- Sponsor's protocol ID
- K2025-06-025
- Status last verified
- Aug 2026
- First submitted
- 27 Nov 2025
- Last updated
- 27 Aug 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Virtual Reality-Based Horticultural Intervention for Older Adults With Subthreshold Depression in Nursing Homes: Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07275034
- Acronym / sponsor ID
- K2025-06-025
- Conditions
- Subthreshold Depression
- Keywords
- older adults, Subthreshold Depression, virutal reality, Gardening
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 62 participants (actual)
- Lead sponsor
- Fujian Medical UniversityUniversity, hospital or other
- Study start
- 10 Nov 2025 (actual)
- Primary completion
- 16 Jan 2026 (actual)
- Study completion
- 16 Jan 2026 (actual)
- First posted
- 10 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Subthreshold depression represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing clinical depression and a critical phase for alleviating depressive symptoms. However, current research predominantly focuses on treating depression in the elderly, with insufficient attention to interventions for high-risk populations or limited to cross-sectional investigations of subthreshold depression risk factors. Therefore, prioritizing subthreshold depression in the elderly and implementing early interventions is essential. A 2024 article in The Lancet suggests that subthreshold depression treatment should prioritize psychotherapy and lifestyle adjustments over medication. Horticultural therapy, an interdisciplinary approach integrating horticulture, medicine, and psychology, demonstrates unique advantages over traditional medical treatments. In practical application, however, limited resources may hinder adequate support for horticultural activities, compromising activity quality, reducing therapeutic efficacy, and restricting the widespread adoption of horticultural therapy. Integrating VR technology with horticultural therapy can provide patients with more comprehensive, personalized, and effective mental health treatment plans, empowering them toward healthier, more positive lives. Therefore, the research team designed a VR horticultural intervention system for elderly individuals with subthreshold depression based on the Social Participation Competence Framework.
Detailed description
Subthreshold depression (SD) represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing major depressive disorder and a critical window for alleviating depressive symptoms. An editorial published in JAMA emphasized that research on subthreshold depression holds significant implications for exploring the prevention and treatment of depression. Therefore, prioritizing subthreshold depression in older adults and implementing early interventions is essential. Global population aging has made mental health disorders a major public health issue. The World Health Organization reports that about 7% of people aged 60 and above worldwide suffer from depression; in China, the rates are 19.05% for mild and 12.17% for moderate-to-severe depressive symptoms. Subthreshold depression (StD) is defined as having at least two depressive symptoms (e.g., anhedonia, loss of interest) for over two weeks without meeting major depressive disorder criteria. Among older adults, StD prevalence is about 18.6%, with a 12%-15.83% risk of progressing to major depression within 2-3 years. Thus, StD represents a critical window for early prevention, and timely non-pharmacological interventions are vital to reverse progression and reduce family and social care burdens.
Virtual Reality (VR) technology, as a novel intervention method, possesses three key characteristics: immersion, interactivity, and simulation. By replicating real-world settings such as home and community environments, it enriches the training experience for elderly individuals with depression, helping them adapt to diverse social contexts and enhancing intervention outcomes. Horticultural therapy, an interdisciplinary approach integrating horticulture, medicine, and psychology, offers relatively low treatment costs with minimal side effects. It plays a positive role in promoting physical recovery, improving emotional well-being, and enhancing social skills. Increasingly, research teams are exploring VR-generated virtual horticultural environments and horticultural activity interventions. VR technology addresses multiple limitations of traditional horticultural therapy. VR-based gardening activities overcome temporal and spatial constraints, reduce the costs and risks associated with physical gardening, and provide richer, more personalized socialized horticultural settings and activities that cater to diverse patient needs. Therefore, integrating VR technology with horticultural therapy offers patients a more comprehensive, personalized, and effective mental health treatment plan, empowering them to lead healthier, more positive lives.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Virtual Reality Intervention | Experimental | Other: Virtual Reality-Based Horticultural Intervention System, Other: routine health managementThis group utilized a virtual reality intervention system based on horticultural planting, designed and developed by the research team. |
| Routine Care | Experimental | Other: routine health managementThe control group received routine health management over the 6-week period, which encompassed assistance with daily living activities, basic medical care (including regular health check-ups and medication management), recreational activities, and environmental cleaning, with no additional structured intervention. |
Who may qualify
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- age ≥ 60 years;
- meeting the diagnostic threshold for StD27, defined as a score ≥ 16 on the Center for Epidemiologic Studies Depression Scale (CES-D);
- adequate visual, auditory, and verbal communication capacity;
- provision of written informed consent.
Key exclusion criteria (7 listed)
- recent exposure to major traumatic events or current suicide risk;
- concurrent participation in other similar studies;
- not currently undergoing psychotherapy;
- current use of antidepressant pharmacotherapy;
- absence of severe cognitive impairment with a Montreal Cognitive Assessment (MoCA) score of >10;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtual Reality-Based Horticultural Intervention SystemThe system comprised six progressive horticultural tasks, each associated with a distinct plant: (1) Tomato Planting, (2) Corn Cultivation, (3) Strawberry Care, (4) Eggplant Harvest, (5) Rose Growing, and (6) Sunflower Expansion. All tasks followed the same eight standardized steps-land preparation, seed sowing, seedling fertilization, initial watering, secondary fertilization, secondary watering, pest removal, and harvesting-but were arranged in a clear gradient of increasing difficulty. This progression was reflected in expanding planting scales, escalating task complexity, heightened cognitive load, more refined judgment requirements, and varying demands on operational precision. Each task was performed individually by the participant using the VR headset, without any multiplayer or collaborative components, as the system was designed for personalized, self-paced intervention. | Other | Virtual Reality Intervention |
| routine health managementThis arm of seniors maintains their daily routines and participates regularly in the nursing home's daily activities. | Other | Routine Care, Virtual Reality Intervention |
Primary outcome
Subthreshold Depression
Time frame: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks .
The Center for Epidemiological Surveys Depression Scale (CES-D) was developed by Rirodiff at the National Institute of Mental Health in the United States. It is designed for screening depressive symptoms in older adults, comprising 20 items. Each question assesses one symptom, covering 20 distinct symptoms in total. The total score ranges from 0 to 60 points. A score ≤15 indicates no depressive symptoms, 16-19 suggests possible depressive symptoms, and ≥20 confirms depressive symptoms. The Cronbach's alpha coefficient for the Chinese population is 0.90. It is one of the most commonly used subthreshold depression epidemiological survey tools, with existing studies defining CES-D ≥16 as subthreshold depression. Translated with DeepL.com (free version)
7 secondary outcomes
General cognitive function
Time frame: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately.
Anxiety Condition
Time frame: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately
Self-Efficacy
Time frame: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately.
Sleep Quality
Time frame: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks separately.
System Usability
Time frame: The intervention will be implemented in November 2025, with the evaluation conducted after the 6-week intervention period concludes.
Simulator Sickness
Time frame: The intervention will be implemented in November 2025, with the evaluation conducted after the 6-week intervention period concludes.
Immersion Presence
Time frame: The intervention will be implemented in November 2025, with the evaluation conducted after the 6-week intervention period concludes.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2026.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Virtual Reality-Based Horticultural Intervention System and routine health management in people with Subthreshold Depression, run by Fujian Medical University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Subthreshold Depression (time frame: The intervention was conducted in November 2025, and the evaluation time was 0,6 weeks .). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026.