Clinical trials: Subthreshold Depression
Subthreshold Depression
Study Protocol for a Smartphone Application-based Intervention for Subthreshold Depression
The investigators plan to conduct a randomized controlled trial to examine whether a Smartphone-based Intervention improves subthreshold depression symptoms compared to no intervention.
- Trial name
- NCT04136041
- Testing
- Smartphone Application
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Kibi International University
Subthreshold Depression, Depressive Symptoms
Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression
Lycium barbarum, a traditional Chinese herbal medicine, is a commonly used herb in the traditional Chinese pharmacopoeia . Its main active ingredient, lycium barbarum polysaccharide (LBP), is reported to have neuroprotective…
- Conditions
- Subthreshold Depression, Depressive Symptoms, Anxious Symptoms
- Trial name
- NCT04032795
- Testing
- Lycium barbarum polysaccharide
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Guangzhou Psychiatric Hospital
Depression
Transcranial Magnetic Stimulation in Depression
The study examines efficacy of repetitive transcranial magnetic stimulation in treating severely depressed patients who are medicated.
- Trial name
- NCT00018746
- Testing
- repetitive transcranial magnetic stimulation
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Subthreshold Depression
Treating Depressed Mood With a Smartphone-delivered Positive Word Stimulation for Subthreshold Depression
Major depressive disorder (MDD) is an important public health problem. Thus, preventive interventions against subthreshold depression (StD), which is one of the key risk factors for the development of MDD, are important.
- Trial name
- NCT04707495
- Testing
- Smartphone Application (SPSRS), Smartphone Application (YouTube)
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Gunma University
Subthreshold Depression
Dietary Education Intervention for Subthreshold Depression (MIND-Trial)
This randomized controlled trial evaluates the efficacy of an 8-week dietary education intervention in adults with subthreshold depression.
- Trial name
- NCT07880652
- Testing
- Mediterranean-Style Dietary Education Program, Befriending
- Where
- Singapore
- Volunteers
- 64 people
- Sponsor
- Institute of Mental Health, Singapore
Subthreshold Depression, Young People
TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is…
- Conditions
- Subthreshold Depression, Young People, Transcranial Direct Current Stimulation
- Trial name
- NCT06294184
- Testing
- tdcs lDLPFC, tdcs rVLPFC
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Subthreshold Depression
Needle-embedding Therapy Alleviates Depressive Symptoms and Resets the Function of Executive Control System in Subthreshold Depression People
The main objective of this trial is to evaluate the effectiveness of treating subthreshold depression by needle-embedding therapy.
- Trial name
- NCT04319562
- Testing
- needle-embedding therapy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Depressive Symptoms, Diabetes Mellitus
Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression
This work is supported by the "Kompetenznetz Diabetes mellitus (Competence Network for Diabetes mellitus)" funded by the Federal Ministry of Education and Research (FKZ 01GI0809).
- Trial name
- NCT01009138
- Testing
- Diabetes-Specific CBT (DS-CBT), Standard Diabetes Education
- Where
- Germany
- Volunteers
- 214 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Irritable Bowel Syndrome With Subthreshold Depression
Lactobacillus-containing Cultured Milk Drink Alleviates Depression Score Among Adults With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is frequently associated with any form of psychiatric comorbidities including subthreshold or subclinical depression.
- Trial name
- NCT05266443
- Testing
- Lactobacillus containing cultured milk drink
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Depression
Treatment of Mild and Subthreshold Depressive Disorders
The purpose of this study is to determine the efficacy of a SSRI, cognitive-bahavioral-therapy and a free choice between SSRI and CBT in a sample of primary care patients suffering from mild to moderate depression.
- Trial name
- NCT00226642
- Testing
- Sertralin, Cognitive-behavioral therapy, Non-specific supporting group therapy
- Where
- Germany
- Volunteers
- 369 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Long-term Physical Health Conditions, Subthreshold Depression
Online Peer Support in Long-term Conditions
Over 15 million people in England live with a long-term physical health condition. Low mood, loneliness and worry related to chronic illness are very common.
- Trial name
- NCT06222346
- Testing
- CommonGround, NHS Mental Health
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- King's College London
Subthreshold Depression, Exercise
The Effect of Exercise on Cognition and Preventing Depression in Young People
It is estimated that approximately 30% of child and adolescents manifest subthreshold depression (including other specified depressive disorder and unspecified depressive disorder), which can further develop into major depression…
- Conditions
- Subthreshold Depression, Exercise, Clinically-well, Cognitive Change
- Trial name
- NCT04816617
- Testing
- Aerobic exercise intervention, Psycho-education
- Where
- China
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Subthreshold Depression
tDCS in People With Subthreshold Depression
This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.
- Trial name
- NCT06517121
- Testing
- Personalized Experimental Transcranial Direct Current Stimulation (tDCS), Conventional Experimental Transcranial Direct Current Stimulation (tDCS)
- Where
- Hong Kong
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Bipolar Disorder NOS
Pilot Study of Interpersonal and Social Rhythm Therapy for Subthreshold Bipolar
The investigators propose to conduct a 20 week open pilot study of Interpersonal and Social Rhythm Therapy (IPSRT) to treat individuals (n=18) with subthreshold bipolar (BP) who are currently depressed.
- Trial name
- NCT01520129
- Testing
- Interpersonal and social rhythm therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
Subthreshold Depression
Effects of Virtual Reality-Based Horticultural Intervention for Older Adults With Subthreshold Depression in Nursing Homes
Subthreshold depression represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing clinical depression and a critical phase for alleviating…
- Trial name
- NCT07275034
- Testing
- Virtual Reality-Based Horticultural Intervention System, routine health management
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Mild Cognitive Impairment, Subthreshold Depression
A One-year Trajectory of Depression Status Changes in Older Adults With MCI and SD: a Longitudinal Cohort Study
The purpose of this study is to investigate the one-year trajectory of changes in depression status in older adults with mild cognitive impairment and subthreshold depression, and to explore relevant risk factors for predicting…
- Conditions
- Mild Cognitive Impairment, Subthreshold Depression, Older Adults
- Trial name
- NCT06308627
- Where
- China
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Depression
Telephone Cognitive-Behavioral Therapy (CBT) for Subthreshold Depression and Presenteeism in Workplace
The purpose of the study is to examine the effectiveness of telephone cognitive-behavioral therapy for subthreshold depression and presenteeism in workplace, in comparison with treatment-as-usual (TAU) (which is minimal contact…
- Trial name
- NCT00885014
- Testing
- CBT, EAP
- Where
- Japan
- Volunteers
- 118 people
- Sponsor
- Kyoto University
Depression
Internet Program for Workers With Subthreshold Depression
Depression is one of the most prevalent mental disorders to afflict adults. It seriously impacts role functioning and often takes a recurrent or chronic course.
- Trial name
- WorkDep (NCT02335554)
- Testing
- MoodHacker, Alternative Care
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Anxiety, Depressive Symptoms
Group Program vs Single-Session Depathologizing Intervention for Subthreshold Anxiety-Depression in Primary Care (Spain)
This study evaluated two psychological interventions for adults with mild to moderate subthreshold anxious-depressive symptoms in primary care in Spain.
- Conditions
- Anxiety, Depressive Symptoms, Anxiety Symptoms, Subthreshold Depression
- Trial name
- NCT07363915
- Testing
- PADAP transdiagnostic CBT-based group program, Active Single-Session Depathologizing Intervention (SSDI)
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- University of Alcala
Mild Cognitive Impairment, Subthreshold Depression
A Trial of Combined Subthreshold Depression in Older Adults With Mild Cognitive Impairment Participating in Art Games
The presence of subthreshold depression accelerates quality of life decline and cognitive impairment in older adults with mild cognitive impairment, increasing the rate of dementia conversion, while the continuous decline in…
- Trial name
- NCT06706739
- Testing
- Online art game intervention group
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Fujian Medical University