Chronic Kidney DiseaseNCT07292311
Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease
A study testing Reliability Assessment and Online Therapeutic Exercise in people with Chronic Kidney Disease and Renal Insufficiency, Chronic, run by University of Extremadura at 1 site in Spain.
Trial summary
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Chronic Kidney Disease, Renal Insufficiency, Chronic, Muscle Weakness
- What is being tested?
- Reliability Assessment and Online Therapeutic Exercise
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteSpain
- Study dates
- 7 Nov 2025to 15 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- ≥18 years old.
- Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant).
- Member of ALCER Association (Badajoz or Cáceres).
- Medical clearance for physical testing/exercise.
Who cannot join
- Severe cognitive or communication impairment.
- Unstable cardiovascular or musculoskeletal conditions.
- Refusal to provide informed consent.
Trial locations and contacts
1 site in 1 country.
Spain1 site
Facultad de Enfermería y Terapia Ocupacional
Cáceres, Cáceres, 10003
About this study
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.
Read the detailed description
Patients with chronic kidney disease experience progressive muscle weakness and reduced physical capacity due to systemic inflammation, metabolic acidosis, and inactivity.
This two-phase observational and interventional study, conducted in collaboration with the ALCER Association (Badajoz and Cáceres, Spain), will:
- Determine the test-retest reliability of muscle assessment tools (isokinetic dynamometer, surface electromyography, and handheld dynamometry).
- Implement and evaluate an online therapeutic exercise program supervised by physiotherapists.
The project aims to provide valid and reliable protocols for neuromuscular assessment in CKD patients and explore the feasibility of remote therapeutic exercise.
- Conditions
- Chronic Kidney Disease, Renal Insufficiency, Chronic, Muscle Weakness, Sarcopenia, Physical Fitness, Physical Therapy Modalities
- Being tested
- Reliability Assessment, Online Therapeutic Exercise
- Keywords
- chronic kidney disease, renal patients, muscle strength assessment, isokinetic testing, surface electromyography, physiotherapy, occupational therapy, functional evaluation, therapeutic exercise
- Medical subject headings
- Renal Insufficiency, Chronic, Muscle Weakness, Sarcopenia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Reliability AssessmentDevice
Device: Isokinetic dynamometer and mDurance® surface EMG Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb
Online Therapeutic ExerciseBehavioural
Behavioral: Online therapeutic exercise program 8-10 week supervised online program including resistance and mobility exercises
| Study group | Role | What they receive |
|---|---|---|
| Reliability Assessment | Active comparator | Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb Receives: Device: Reliability Assessment |
| Online Therapeutic Exercise | Experimental | 8-10 week supervised online program including resistance and mobility exercises Receives: Behavioral: Online Therapeutic Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Test-retest reliability of surface EMG (Electromiography) activation.
RMS (root mean square). microvolts
Measured: 7-10 days
Test-retest reliability of isokinetic strength
Intraclass Correlation Coefficient - ICC. Strength (kilograms)
Measured: 7-10 days
Change in handgrip and limb strength measured by VALD dynamometry
strength (kilograms)
Measured: Baseline and 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Dec 2025
- Study start7 Nov 2025
- Primary completion30 Jan 2026 (estimated)
- Study completion15 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Kidney DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Extremadura
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Alejandro Caña Pino, University of Extremadura
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07292311
- Sponsor's protocol ID
- 071125
- Status last verified
- Nov 2025
- First submitted
- 5 Dec 2025
- Last updated
- 18 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease
- ClinicalTrials.gov ID
- NCT07292311
- Acronym / sponsor ID
- 071125
- Conditions
- Chronic Kidney Disease, Renal Insufficiency, Chronic, Muscle Weakness, Sarcopenia, Physical Fitness, Physical Therapy Modalities
- Keywords
- chronic kidney disease, renal patients, muscle strength assessment, isokinetic testing, surface electromyography, physiotherapy, occupational therapy, functional evaluation
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University of ExtremaduraUniversity, hospital or other
- Study start
- 7 Nov 2025 (actual)
- Primary completion
- 30 Jan 2026 (estimated)
- Study completion
- 15 May 2026 (estimated)
- First posted
- 18 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.
Detailed description
Patients with chronic kidney disease experience progressive muscle weakness and reduced physical capacity due to systemic inflammation, metabolic acidosis, and inactivity.
This two-phase observational and interventional study, conducted in collaboration with the ALCER Association (Badajoz and Cáceres, Spain), will:
- Determine the test-retest reliability of muscle assessment tools (isokinetic dynamometer, surface electromyography, and handheld dynamometry).
- Implement and evaluate an online therapeutic exercise program supervised by physiotherapists.
The project aims to provide valid and reliable protocols for neuromuscular assessment in CKD patients and explore the feasibility of remote therapeutic exercise.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Reliability Assessment | Active comparator | Device: Reliability AssessmentTest-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb |
| Online Therapeutic Exercise | Experimental | Behavioral: Online Therapeutic Exercise8-10 week supervised online program including resistance and mobility exercises |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- ≥18 years old.
- Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant).
- Member of ALCER Association (Badajoz or Cáceres).
- Medical clearance for physical testing/exercise.
Key exclusion criteria (3 listed)
- Severe cognitive or communication impairment.
- Unstable cardiovascular or musculoskeletal conditions.
- Refusal to provide informed consent.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Reliability AssessmentDevice: Isokinetic dynamometer and mDurance® surface EMG Test-retest reliability of isokinetic and surface EMG measurements in upper limb, trunk, and lower limb | Device | Reliability Assessment |
| Online Therapeutic ExerciseBehavioral: Online therapeutic exercise program 8-10 week supervised online program including resistance and mobility exercises | Behavioural | Online Therapeutic Exercise |
Primary outcome
Test-retest reliability of surface EMG (Electromiography) activation.
Time frame: 7-10 days
RMS (root mean square). microvolts
Test-retest reliability of isokinetic strength
Time frame: 7-10 days
Intraclass Correlation Coefficient - ICC. Strength (kilograms)
Change in handgrip and limb strength measured by VALD dynamometry
Time frame: Baseline and 12 weeks
strength (kilograms)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Dec 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Reliability Assessment and Online Therapeutic Exercise in people with Chronic Kidney Disease and Renal Insufficiency, Chronic, run by University of Extremadura at 1 site in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 18 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Test-retest reliability of surface EMG (Electromiography) activation. (time frame: 7-10 days). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Dec 2025; AzTrials last refreshed its copy on 7 Nov 2026.