AstigmatismNCT07303920
Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day
A study testing Daily disposable contact lenses for astigmatism in people with Astigmatism, run by Ohio State University at 1 site in United States.
Trial summary
The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear. Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Astigmatism
- What is being tested?
- Daily disposable contact lenses for astigmatism
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 4 Mar 2026to 30 Dec 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Current soft toric contact lens wearer with long hours of wear
- Willing to follow the contact lens wearing schedule required by the study
- Vision 20/25 or better with current soft toric contact lenses
- Self-report completion of a comprehensive eye examination in the past two years
Who cannot join
- Have a history of corneal ocular surgery
- Have current ocular inflammation or infection as assessed by the study investigator who will complete the study
- Are past rigid contact lens wearers
- Have a history of being diagnosed with dry eye or ocular allergies
- Have known systemic health conditions that are thought to alter tear film physiology
- Have a history of viral eye disease
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- Have a history of ocular surgery
- Have a history of severe ocular trauma
- Have a history of corneal dystrophies or degenerations
- Have active ocular infection or inflammation
- Are currently using isotretinoin-derivatives or ocular medications
- Are pregnant or breast feeding
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
The Ohio State University College of Optometry
Columbus, Ohio, 43210
Emma Grant, 614-292-8858, OPT-EyeStudies@osu.edu
Emily Wagner, 614-292-8858, OPT-EyeStudies@osu.edu
About this study
The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.
- Conditions
- Astigmatism
- Being tested
- Daily disposable contact lenses for astigmatism
- Medical subject headings
- Astigmatism
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Daily disposable contact lenses for astigmatismDevice
Also called Dailies Total1 for Astigmatism
All participants will be fit with the study lenses
| Study group | Role | What they receive |
|---|---|---|
| Contact Lens Wear | Other | All participants will be fit with the study contact lenses for astigmatism Receives: Device: Daily disposable contact lenses for astigmatism |
What is being measured
The primary outcome is the main question the study is designed to answer.
Comfort
Proportion of participants with positive Visual Analog Scale (VAS, >50 on a 0-100 scale)
Measured: Measured over 16 hours of wear
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Dec 2025
- Study start4 Mar 2026
- Primary completion30 Dec 2026 (estimated)
- Study completion30 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AstigmatismStudies of the same condition, open and under way.
- More trials run by Ohio State UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ohio State University
- Sponsor type
- University, hospital or other
- Collaborators
- Alcon Research
- Responsible party
- Principal investigator, Jennifer Fogt, Ohio State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07303920
- Sponsor's protocol ID
- 20252462
- Status last verified
- Sep 2026
- First submitted
- 23 Dec 2025
- Last updated
- 25 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- No