Peripherally Inserted Central CathetersNCT07369427
Magnetic Tracking and ECG-Guided Tip Confirmation System for PICCs
An observational study of Peripherally Inserted Central Catheters, run by Sun Yat-sen University at 1 site in China.
Trial summary
This prospective study enrolled cancer patients who underwent peripherally inserted central catheter (PICC) placement at a tertiary care oncology hospital in Guangzhou between January 1st and May 30th, 2026. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Peripherally Inserted Central Catheters
- What is being tested?
- Sherlock 3CG Tip Confirmation System
- How many people
- 176 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2026to 30 Jun 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Cancer patients who receiving PICC placement
Who may be able to join
- cancer patients receiving PICC placement
- High risk of PICC-related thrombosis(Evaluated by Caprini score ≥ 5)
- Agree to receive PICC maintenance at the research hospital;
- Sign the informed consent form
Who cannot join
- PICC placed in the lower limb
- Estimated survival time less than one month
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510000
Zeyin Hu, 15899954190, huzy@sysucc.org.cn
About this study
Official title: Magnetic Tracking and Electrocardiography-Guided Tip Confirmation System for Placement of Peripherally Inserted Central Catheters
This prospective study enrolled cancer patients who underwent peripherally inserted central catheter (PICC) placement at a tertiary care oncology hospital in Guangzhou between January 1st and May 30th, 2026. Data on catheterization outcomes and complications were collected to compare two tip positioning techniques: electromagnetic navigation tip positioning and traditional electrocardiogram (ECG)-guided positioning. The outcomes assessed included first-attempt catheterization success rate, tip positioning accuracy, catheterization procedure time, post-procedural catheter adjustment time, and the incidence of complications (thrombosis, infection, and catheter dysfunction) within 4 weeks post-catheterization.
- Conditions
- Peripherally Inserted Central Catheters
- Being tested
- Sherlock 3CG Tip Confirmation System
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sherlock 3CG Tip Confirmation SystemOther
Sherlock 3CG Tip Confirmation System: An integrated system combining magnetic navigation tracking and ECG guidance. It dynamically confirms the tip's position relative to the target anatomical location (e.g., superior vena cava-right atrial junction) by real-time tracking of the catheter tip's spatial position via magnetic navigation and synchronously monitoring ECG signals (e.g., P-wave changes).
Traditional ECG-Guided Tip Positioning Technology: Relying solely on ECG monitoring for guidance, it assists in determining the tip position via characteristic waveform changes in intracardiac ECG signals (e.g., changes in P-wave amplitude) derived from the catheter tip electrode as the tip approaches the target location, serving as a conventional positioning method.
| Study group | Role | What they receive |
|---|---|---|
| cancer patients who undergo PICC placement (Caprini score ≥5) | Not described Receives: Other: Sherlock 3CG Tip Confirmation System |
What is being measured
The primary outcome is the main question the study is designed to answer.
one time catheterization rate
Measured: data will be collected on Day 1
Secondary outcomes (4)
time for catheter tip positioning during catheterization
Measured: on Day 1
time for catheter tip adjustment after catheterization
Measured: on Day 1
rate of correct catheter tip positioning
Measured: on Day 1
rate of PICC-related complications
Measured: within 4 weeks after catheterization
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2026
- Study start1 Jan 2026
- Primary completion30 May 2026 (estimated)
- Study completion30 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Peripherally Inserted Central CathetersStudies of the same condition, open and under way.
- More trials run by Sun Yat-sen UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 176 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sun Yat-sen University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zeyin Hu, Sun Yat-sen University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07369427
- Sponsor's protocol ID
- SunYat-senU6
- Status last verified
- May 2026
- First submitted
- 27 Sep 2025
- Last updated
- 7 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 7 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Magnetic Tracking and Electrocardiography-Guided Tip Confirmation System for Placement of Peripherally Inserted Central Catheters
- ClinicalTrials.gov ID
- NCT07369427
- Acronym / sponsor ID
- SunYat-senU6
- Conditions
- Peripherally Inserted Central Catheters
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 176 participants (estimated)
- Lead sponsor
- Sun Yat-sen UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 30 May 2026 (estimated)
- Study completion
- 30 Jun 2026 (estimated)
- First posted
- 27 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective study enrolled cancer patients who underwent peripherally inserted central catheter (PICC) placement at a tertiary care oncology hospital in Guangzhou between January 1st and May 30th, 2026. Data on catheterization outcomes and complications were collected to compare two tip positioning techniques: electromagnetic navigation tip positioning and traditional electrocardiogram (ECG)-guided positioning. The outcomes assessed included first-attempt catheterization success rate, tip positioning accuracy, catheterization procedure time, post-procedural catheter adjustment time, and the incidence of complications (thrombosis, infection, and catheter dysfunction) within 4 weeks post-catheterization.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| cancer patients who undergo PICC placement (Caprini score ≥5) | – | Other: Sherlock 3CG Tip Confirmation System |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Cancer patients who receiving PICC placement
Key inclusion criteria (4 listed)
- cancer patients receiving PICC placement
- High risk of PICC-related thrombosis(Evaluated by Caprini score ≥ 5)
- Agree to receive PICC maintenance at the research hospital;
- Sign the informed consent form
Key exclusion criteria (2 listed)
- PICC placed in the lower limb
- Estimated survival time less than one month
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sherlock 3CG Tip Confirmation SystemSherlock 3CG Tip Confirmation System: An integrated system combining magnetic navigation tracking and ECG guidance. It dynamically confirms the tip's position relative to the target anatomical location (e.g., superior vena cava-right atrial junction) by real-time tracking of the catheter tip's spatial position via magnetic navigation and synchronously monitoring ECG signals (e.g., P-wave changes). Traditional ECG-Guided Tip Positioning Technology: Relying solely on ECG monitoring for guidance, it assists in determining the tip position via characteristic waveform changes in intracardiac ECG signals (e.g., changes in P-wave amplitude) derived from the catheter tip electrode as the tip approaches the target location, serving as a conventional positioning method. | Other | cancer patients who undergo PICC placement (Caprini score ≥5) |
Primary outcome
one time catheterization rate
Time frame: data will be collected on Day 1
4 secondary outcomes
time for catheter tip positioning during catheterization
Time frame: on Day 1
time for catheter tip adjustment after catheterization
Time frame: on Day 1
rate of correct catheter tip positioning
Time frame: on Day 1
rate of PICC-related complications
Time frame: within 4 weeks after catheterization
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 May 2026.
- Individual participant dataSharing planned: Undecided
Related trials for Peripherally Inserted Central Catheters
Not yet recruitingObservational study
Umbilical Venous Versus Peripherally Inserted Central Catheters in Neonates: A Prospective Cohort Study of Complications, Catheter Survival, and CLABSI"
Peripherally Inserted Central Catheter, Umbilical Venous Catheter
Active, not recruiting
AR Ruler to Improve Safety and Clinical Workflow During PICC Placement
Insertion of Peripherally Inserted Central Catheter
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Peripherally Inserted Central Catheters, run by Sun Yat-sen University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Zeyin Hu, Master (+8615899954190, huzy@sysucc.org.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
one time catheterization rate (time frame: data will be collected on Day 1). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 May 2026.