Clinical trials: Peripherally Inserted Central Catheters
Cancer, Central Venous Catheterization
Study of Sodium Bicarbonate in Restoring Blocked Catheters
This is a study looking at the use of sodium bicarbonate to restore the flow of blocked central line devices in patients with blood cancers.
- Trial name
- NCT03348826
- Testing
- Sodium Bicarbonate 8.4% Solution for Injection, Alteplase Injectable Solution
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Catheterization, Peripheral
Study of Peripherally Inserted Central Catheter (PICC)-Related Infections in a Tropical Area
Septi-PICC study aims at assessing incidence of Peripherally Inserted Central Catheter (PICC)-related infections among patients managed in the University Hospital of La Reunion for PICC setting.
- Conditions
- Catheterization, Peripheral, Infection
- Trial name
- Septi-PICC (NCT02899546)
- Where
- France
- Volunteers
- 283 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Vascular Access Complication, Vascular Access Related Infection
Arrow Chloragard Peripherally-Inserted Central Catheters (PICC) Study
A prospective study evaluating the timing, incidence and relationship of commonly occurring complications related to the use of peripherally-inserted central catheters.
- Trial name
- NCT03019302
- Testing
- Arrow PICC with Chloragard Technology
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Teleflex
Peripherally Inserted Central Catheters
Comparison of an Antibiotic Impregnated PICC Catheter Versus a Regular PICC Catheter in a Tertiary Care Setting
To determine whether antibiotic impregnated PICC catheters have a lower infection rate than a conventional PICC catheter in a tertiary care patient population.
- Trial name
- NCT01765738
- Testing
- PICC (Cook, Bard)
- Where
- United States
- Sponsor
- Medical University of South Carolina
Early Stage Breast Carcinoma
Tolerance of PICC Line Versus Implanted Port for Adjuvant Chemotherapy in Early Breast Cancer
Adjuvant chemotherapy is frequently proposed to patients presenting early breast cancer, in case of high risk of recurrence (large tumors, node involvement, high grade…).
- Trial name
- EPIC (NCT02095743)
- Testing
- implanted port for chemo administration (X-port isp), Use of a PICC line for chemo administration (PowerPICC SOLO²)
- Where
- France
- Volunteers
- 256 people
- Sponsor
- Centre Henri Becquerel
Cardiovascular Infections, Peripheral Vascular Disease
Placement of Peripherally Inserted Central Venous Catheters (PICC) in Children Guided by Ultrasound
Aimed to compare the success in the peripheral intravenous puncture (PIP), progression and placement of PICC in children, according to the use of Doppler vascular ultrasound (DVUS) or traditional method; to identify the influence…
- Trial name
- NCT01279642
- Testing
- ultrasound, traditional puncture
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Infusions, Intravenous, Administration, Intravenous
Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience
The study focuses on patients who require outpatient infusion of therapy ("Infusions, Intravenous"[Mesh]) "Administration, Intravenous"[Mesh] ("Home Infusion Therapy"[Mesh]) "Parenteral Nutrition, Home"[Mesh] via a peripherally…
- Conditions
- Infusions, Intravenous, Administration, Intravenous, Home Infusion Therapy, Parenteral Nutrition, Home
- Trial name
- SpadCare (NCT06905119)
- Testing
- Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- Fundacion Miguel Servet
Cancer
Study Comparing the Efficacy of Peripherally Inserted Central Catheter (PICC) Placement With the Addition of Cyanoacrylate Glue Versus PICC Placement Alone in Patients With Cancer.
This is a randomized, prospective, single-center trial comparing the efficacy of peripherally inserted central catheter (PICC) with the addition of cyanoacrylate glue versus PICC placement alone (without glue) in cancer patients.
- Trial name
- PICCandGLUE (NCT05944900)
- Testing
- Cyanoacrylate glue application
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Centre Leon Berard
CLABSI - Central Line Associated Bloodstream Infection, Deep Vein Thrombosis
Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes
The aim of this multicenter randomized clinical trial is to compare the tunneling technique of PICC insertion with the non-tunneled insertion technique in the incidence of the combined or isolated outcome of catheter-related…
- Conditions
- CLABSI - Central Line Associated Bloodstream Infection, Deep Vein Thrombosis, Dislodged Catheter, Occlusion
- Trial name
- NCT06365528
- Testing
- Subcutaneous tunnelling, Non-tunnelling
- Where
- Brazil
- Volunteers
- 840 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Occlusion
Citrate 4% Versus Heparinised Saline in Preventing Peripherally Inserted Central Catheter (PICC) Occlusions
This study is a prospective, randomized, non-blinded study. 1 group will be assigned the standard arm with use of heparinised saline (10U/ml) lock in between each catheter use.
- Trial name
- NCT03114722
- Testing
- Citrate 4%, Heparinised saline (10U/ml)
- Where
- Singapore
- Volunteers
- 130 people
- Sponsor
- National University Hospital, Singapore
Peripherally Inserted Central Catheter Insertion Technique
The Application of Neck Ultrasound in the Assessment of Peripherally Inserted Central Catheter (PICC) Tip Position
Insertion of peripherally inserted central catheters (PICCs) at the bedside may result in tip malposition. This study was designed to evaluate whether the addition of ultrasound (US) inspection of the ipsilateral neck provides…
- Trial name
- NCT00565877
- Testing
- Ultrasound inspection
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Chicago
PICC Line Placement, Vessels; Anomaly
Image-Guided Central Catheter Insertion With Concurrent Assessment of Vascular Wall Integrity
The insertion of peripherally inserted central catheters (PICCs) represents a minimally invasive and safe method for establishing long-term central venous access in patients requiring prolonged intravenous therapy, including…
- Trial name
- NCT07466472
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Peripherally Inserted Central Catheter
Prospective Observational Study of the Power PICC Family of Devices and Accessories
Post-market, observational study to collect prospective data related to the safety and performance of the Power PICC family of devices and its accessories in a real-world setting.
- Trial name
- NCT04263649
- Testing
- Peripherally Inserted Central Catheter
- Where
- 14 sites in Austria, Belgium and 7 more
- Volunteers
- 450 people
- Sponsor
- Becton, Dickinson and Company
Peripherally Inserted Central Catheters
Magnetic Tracking and ECG-Guided Tip Confirmation System for PICCs
This prospective study enrolled cancer patients who underwent peripherally inserted central catheter (PICC) placement at a tertiary care oncology hospital in Guangzhou between January 1st and May 30th, 2026.
- Trial name
- NCT07369427
- Testing
- Sherlock 3CG Tip Confirmation System
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Sun Yat-sen University
Hemodynamics, Central Venous Pressure
Reliability of Central Venous Pressure Measurements
The purpose of this study is to compare CVP measurements from CICCs and PICCs. The investigators will also evaluate whether or not the duration of CICC placement affects the differences in CVP measurements between the CICCs and…
- Trial name
- CVP (NCT01116973)
- Testing
- PICC
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Oklahoma
Peripherally Inserted Central Catheter
Comparing Arrow PICC Catheters w/ Arrowga+rd Blue Advanced Protection Performance and Safety to Unprotected PICC's
This study seeks to compare the standard unprotected PICC with the AGBA PICC for placement success, incidence of venous thrombosis through duplex ultrasound, observing for signs and symptoms of thrombotic occlusion and recording…
- Trial name
- NCT05278507
- Testing
- Arrowga+rd Blue Advance Protection PICC Placement
- Where
- 5 sites in China
- Volunteers
- 444 people
- Sponsor
- Teleflex
Peripherally Inserted Central Catheters
Point of Care Ultrasound for PICC Line Monitoring Study
A prospective comparative study evaluating chest x-ray determination of PICC line tip location and POC ultrasound PICC line tip location.
- Trial name
- PUP (NCT03954977)
- Testing
- PICC line ultrasound
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Upper Extremity Deep Vein Thrombosis
Major Complications Related to PICC and Midline Insertion
Most important peripherally inserted central catheter (PICC) and Midline complications are thrombosis and catheter related blood stream infections.
- Trial name
- PICC/MIDLINE (NCT02489721)
- Testing
- PICC and Midline
- Where
- Italy
- Volunteers
- 547 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Bacterial Infections
Study of Complication Rates Associated With PICC for Left vs Right
Peripherally inserted central catheter (PICC) are catheters that are placed mainly in the arms, but which pass in the veins to beside the heart.
- Trial name
- NCT01638702
- Testing
- Follow up of complications
- Where
- 2 sites in Canada
- Volunteers
- 203 people
- Sponsor
- Richard Lindsay
Taurolidine Lock Solution
Survey of Practices Regarding the Use of Taurolidine Lock Solutions in Patients With Insertion of a Peripherally Inserted Central Catheter (PICC) in a Vascular Access Unit
The primary objective of this study is to describe current practices regarding the administration of taurolidine lock solutions in relation to medical prescriptions for patients who have undergone peripherally inserted central…
- Trial name
- TAURO-USE2 (NCT07259421)
- Volunteers
- 45 people
- Sponsor
- University Hospital, Grenoble