DynapeniaNCT07375888
The Application of an Innovative Reactive Agility Testing System for Assessment in Older Adults With Dynapenia
An observational study of Dynapenia, run by Kaohsiung Medical University at 1 site in Taiwan.
Trial summary
Before the experiment, the researchers explain the purpose and procedures to the participants. After signing the informed consent form and completing basic personal information, participants perform a 5-minute warm-up. Read more about this study
- Who is it for?
- Ages 65 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Dynapenia
- What is being tested?
- Reactive Agility Testing System
- How many people
- 104 participants
- Where
- 1 siteTaiwan
- Study dates
- 24 Nov 2025to 24 Dec 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 80 years
- All sexes
- Healthy volunteers accepted
- Older adult
Study population: Community-dwelling older adults aged 65 years and above Able to communicate with the researchers through spoken or written language Able to cooperate with all required assessments
Who may be able to join
- Community-dwelling older adults aged 65 years and above
- Able to communicate with the researchers through spoken or written language
- Able to cooperate with all required assessments
Who cannot join
- Individuals with cognitive impairment
- Individuals who experience chest pain during recent exercise
- Individuals with angina or joint pain
- Individuals with congestive heart failure
- Individuals who have been advised by a physician not to exercise
- Patients with cancer currently receiving chemotherapy or radiotherapy
- Individuals with neuromuscular disorders or musculoskeletal injuries involving the ankle, knee, or hip joints
Trial locations and contacts
1 site in 1 country.
About this study
Before the experiment, the researchers explain the purpose and procedures to the participants. After signing the informed consent form and completing basic personal information, participants perform a 5-minute warm-up. They then practice the test procedure 1-3 times to become familiar with the visual stimuli, followed by a 3-minute rest before the formal experiment.
Body composition and physical performance are assessed using handgrip strength, the five-time sit-to-stand test, and the skeletal muscle mass index.
Read more
Fall risk is evaluated using a localized fall risk awareness questionnaire.
Agility is tested using a reaction-based running task. Participants stand in a 1 m × 1 m preparation area, and one of two sensor lights placed 3 meters away lights up randomly. Participants run forward, pass through a photo gate, and touch the light to turn it off. Decision time, movement time, and total time are recorded over 10 trials.
Read the detailed description
Before the experiment begins, the researchers will first explain the experimental procedures and purpose to the participants. Participants will then complete an informed consent form and provide their basic personal information. After that, participants will perform a 5-minute warm-up exercise.
To familiarize participants with the visual stimuli, they will practice the test procedure one to three times. After the practice session, participants will rest for 3 minutes before the formal experiment begins.
- (1) Body Composition and Physical Performance Data
- Handgrip Strength: Measured using a handgrip dynamometer. Three trials are performed, and the maximum value is recorded as the handgrip strength.
- Five-Time Sit-to-Stand Test: The participant sits on a standard testing chair with the hips and knees flexed at 90 degrees. Without using the hands for assistance, the participant performs five sit-to-stand movements as quickly as possible. The completion time is recorded.
- Skeletal Muscle Mass Index (SMI): The participant stands barefoot on the measurement device and holds the hand electrodes to obtain appendicular muscle mass. The appendicular muscle mass is then divided by height squared to calculate the skeletal muscle mass index.
- (2) Fall Risk
Fall risk is assessed using a localized Fall Risk Awareness Scale. A higher score indicates a greater risk of falling and a higher level of fear of falling.
### (3) Agility Test
The participant stands in the preparation area located at the center of the testing field, which measures 1 m × 1 m. One sensor light is placed on each side, each positioned 3 meters away from the preparation area.
After the system is activated, one of the lights will illuminate randomly between 1 and 5 seconds. Once the light turns on, the participant moves forward quickly, passes through a photo gate next to the preparation area, and continues forward until touching the sensor light to turn it off.
The system records:
- Decision time: the time from when the light turns on to when the participant passes through the photo gate.
- Movement time: the time from passing through the photo gate to touching and turning off the sensor light.
After a total of 10 trials (combined left and right sides), the test ends. Finally, the system calculates the total time, which is the sum of the decision time and movement time.
- Conditions
- Dynapenia
- Being tested
- Reactive Agility Testing System
- Keywords
- Dynapenia, Elderly
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Reactive Agility Testing SystemDiagnostic test
The participant stands in the preparation area located at the center of the testing field, which measures 1 m × 1 m. One sensor light is placed on each side, with each light positioned 3 meters away from the preparation area.
After the system is activated, one of the lights will illuminate randomly between 1 and 5 seconds. Once the light turns on, the participant moves forward quickly, passes through a photo gate next to the preparation area, and continues forward until touching the sensor light to turn it off.
The system records the time from when the light turns on to when the participant passes through the photo gate, which is defined as the decision time. The time from passing through the photo gate to touching and turning off the sensor light is defined as the movement time.
After completing five trials on each side, the test ends. Finally, the system calculates the total time, which is the sum of the decision time and movement time.
| Study group | Role | What they receive |
|---|---|---|
| Healthy Elderly | Normal muscle mass Normal muscle strength Normal physical performance Receives: Diagnostic Test: Reactive Agility Testing System | |
| Pre sarcopenia | Low muscle mass Normal muscle strength Normal physical performance Receives: Diagnostic Test: Reactive Agility Testing System | |
| Sarcopenia | Low muscle mass Low muscle strength or low physical performance Receives: Diagnostic Test: Reactive Agility Testing System | |
| Dynapenia | Normal muscle mass Low muscle strength or low physical performance Receives: Diagnostic Test: Reactive Agility Testing System |
What is being measured
The primary outcome is the main question the study is designed to answer.
Decision time
The system records the time from when the light turns on to when the participant passes through the photo gate, which is defined
Measured: From participant enrollment to the end of testing
movement time
The time from passing through the photo gate to touching and turning off the sensor light
Measured: From participant enrollment to the end of testing
Secondary outcomes (3)
Handgrip Strength
Measured using a handgrip dynamometer. Three trials are performed, and the highest value is recorded as handgrip strength.
Measured: From participant enrollment to the end of testing
Five-Time Sit-to-Stand Test
The participant sits on a standard testing chair with the hips and knees flexed at 90 degrees. Without using the hands for assistance, the participant performs five sit-to-stand movements as quickly as possible. The completion time is recorded.
Measured: From participant enrollment to the end of testing
Skeletal Muscle Mass Index (SMI)
The participant stands barefoot on the measurement device and holds the hand electrodes to obtain appendicular muscle mass. The appendicular muscle mass is then divided by height squared to calculate the skeletal muscle mass index.
Measured: From participant enrollment to the end of testing
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jan 2026
- Study start24 Nov 2025
- Primary completion24 Dec 2025
- Study completion24 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DynapeniaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 104 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kaohsiung Medical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fan-Chen Liu, Kaohsiung Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07375888
- Sponsor's protocol ID
- KMUHIRB-E(I)-20250028
- Other IDs
- KMUHIRB-E(I)-20250028
- Status last verified
- Jan 2026
- First submitted
- 14 Jan 2026
- Last updated
- 29 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 29 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Application of an Innovative Reactive Agility Testing System for Assessment in Older Adults With Dynapenia
- ClinicalTrials.gov ID
- NCT07375888
- Acronym / sponsor ID
- KMUHIRB-E(I)-20250028
- Conditions
- Dynapenia
- Keywords
- Dynapenia, Elderly
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 104 participants (actual)
- Lead sponsor
- Kaohsiung Medical UniversityUniversity, hospital or other
- Study start
- 24 Nov 2025 (actual)
- Primary completion
- 24 Dec 2025 (actual)
- Study completion
- 24 Dec 2025 (actual)
- First posted
- 29 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Before the experiment, the researchers explain the purpose and procedures to the participants. After signing the informed consent form and completing basic personal information, participants perform a 5-minute warm-up. They then practice the test procedure 1-3 times to become familiar with the visual stimuli, followed by a 3-minute rest before the formal experiment.
Body composition and physical performance are assessed using handgrip strength, the five-time sit-to-stand test, and the skeletal muscle mass index.
Fall risk is evaluated using a localized fall risk awareness questionnaire.
Agility is tested using a reaction-based running task. Participants stand in a 1 m × 1 m preparation area, and one of two sensor lights placed 3 meters away lights up randomly. Participants run forward, pass through a photo gate, and touch the light to turn it off. Decision time, movement time, and total time are recorded over 10 trials.
Detailed description
Before the experiment begins, the researchers will first explain the experimental procedures and purpose to the participants. Participants will then complete an informed consent form and provide their basic personal information. After that, participants will perform a 5-minute warm-up exercise.
To familiarize participants with the visual stimuli, they will practice the test procedure one to three times. After the practice session, participants will rest for 3 minutes before the formal experiment begins.
- (1) Body Composition and Physical Performance Data
- Handgrip Strength: Measured using a handgrip dynamometer. Three trials are performed, and the maximum value is recorded as the handgrip strength.
- Five-Time Sit-to-Stand Test: The participant sits on a standard testing chair with the hips and knees flexed at 90 degrees. Without using the hands for assistance, the participant performs five sit-to-stand movements as quickly as possible. The completion time is recorded.
- Skeletal Muscle Mass Index (SMI): The participant stands barefoot on the measurement device and holds the hand electrodes to obtain appendicular muscle mass. The appendicular muscle mass is then divided by height squared to calculate the skeletal muscle mass index.
- (2) Fall Risk
Fall risk is assessed using a localized Fall Risk Awareness Scale. A higher score indicates a greater risk of falling and a higher level of fear of falling.
### (3) Agility Test
The participant stands in the preparation area located at the center of the testing field, which measures 1 m × 1 m. One sensor light is placed on each side, each positioned 3 meters away from the preparation area.
After the system is activated, one of the lights will illuminate randomly between 1 and 5 seconds. Once the light turns on, the participant moves forward quickly, passes through a photo gate next to the preparation area, and continues forward until touching the sensor light to turn it off.
The system records:
- Decision time: the time from when the light turns on to when the participant passes through the photo gate.
- Movement time: the time from passing through the photo gate to touching and turning off the sensor light.
After a total of 10 trials (combined left and right sides), the test ends. Finally, the system calculates the total time, which is the sum of the decision time and movement time.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Healthy Elderly | – | Diagnostic Test: Reactive Agility Testing SystemNormal muscle mass Normal muscle strength Normal physical performance |
| Pre sarcopenia | – | Diagnostic Test: Reactive Agility Testing SystemLow muscle mass Normal muscle strength Normal physical performance |
| Sarcopenia | – | Diagnostic Test: Reactive Agility Testing SystemLow muscle mass Low muscle strength or low physical performance |
| Dynapenia | – | Diagnostic Test: Reactive Agility Testing SystemNormal muscle mass Low muscle strength or low physical performance |
Who may qualify
- Ages
- 65 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
- Study population
- Community-dwelling older adults aged 65 years and above Able to communicate with the researchers through spoken or written language Able to cooperate with all required assessments
Key inclusion criteria (3 listed)
- Community-dwelling older adults aged 65 years and above
- Able to communicate with the researchers through spoken or written language
- Able to cooperate with all required assessments
Key exclusion criteria (7 listed)
- Individuals with cognitive impairment
- Individuals who experience chest pain during recent exercise
- Individuals with angina or joint pain
- Individuals with congestive heart failure
- Individuals who have been advised by a physician not to exercise
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Reactive Agility Testing SystemThe participant stands in the preparation area located at the center of the testing field, which measures 1 m × 1 m. One sensor light is placed on each side, with each light positioned 3 meters away from the preparation area. After the system is activated, one of the lights will illuminate randomly between 1 and 5 seconds. Once the light turns on, the participant moves forward quickly, passes through a photo gate next to the preparation area, and continues forward until touching the sensor light to turn it off. The system records the time from when the light turns on to when the participant passes through the photo gate, which is defined as the decision time. The time from passing through the photo gate to touching and turning off the sensor light is defined as the movement time. After completing five trials on each side, the test ends. Finally, the system calculates the total time, which is the sum of the decision time and movement time. | Diagnostic test | Dynapenia, Healthy Elderly, Pre sarcopenia, Sarcopenia |
Primary outcome
Decision time
Time frame: From participant enrollment to the end of testing
The system records the time from when the light turns on to when the participant passes through the photo gate, which is defined
movement time
Time frame: From participant enrollment to the end of testing
The time from passing through the photo gate to touching and turning off the sensor light
3 secondary outcomes
Handgrip Strength
Time frame: From participant enrollment to the end of testing
Five-Time Sit-to-Stand Test
Time frame: From participant enrollment to the end of testing
Skeletal Muscle Mass Index (SMI)
Time frame: From participant enrollment to the end of testing
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jan 2026.
- Individual participant dataSharing planned: Yes
Related trials for Dynapenia
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Blood Flow Restriction Parameters and Lower Limb Function in Older Adults With Dynapenia
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Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
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Enrolling by invitation
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Dynapenia, run by Kaohsiung Medical University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Decision time (time frame: From participant enrollment to the end of testing). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jan 2026.