AzTrials
AzTrials

Lumbar RadiculopathyNCT07384832

Comparative Effects of Dynamic Stretching Versus Slider Neurodynamic Technique In Patients With Lumbar Radiculopathy

A study testing Dynamic stretching, slider neurodynamic mobilization and Routine physiotherapy in people with Lumbar Radiculopathy, run by University of Lahore at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

This study will be a randomised clinical trial conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan. A total of 72 participants will be selected and randomly allocated into two treatment groups (36 participants in each group) using the lottery method. Read more about this study

Who is it for?
Ages 25 to 50 years
Conditions the study is for
Lumbar Radiculopathy
What is being tested?
Dynamic stretching, slider neurodynamic mobilization and Routine physiotherapy
Could I receive a placebo?
No, everyone receives an active treatment
How many people
72 participants
Where
1 sitePakistan
Study dates
20 Jun 2025to 10 Feb 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 25 to 50 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • • Participants aged between 25 - 50 years of both genders are included
  • Symptoms that radiate below the buttocks, thigh/ knee, and lower leg for more than 4 weeks.
  • A minimum baseline Pain intensity (NPRS) >4/10. (Morsi et al., 2022)
  • Diagnosis of discogenic low back pain (LBP) confirmed by MRI ( disc bulge, protrusion, and herniation) and referred by an orthopedic physician.
  • LBP due to muscle tightness/ or nerve compression.
  • Had a positive slump test with reproduction of neurological symptoms, and had functional disabilities in certain daily tasks as lifting or walking.

Who cannot join

  • Patients with lumbar spondylolisthesis.
  • Currently pregnant women or in the early post-partum period.
  • Patients with autoimmune disease (ankylosing spondylitis, RA)
  • Previous history of trauma ( fracture, soft tissue injuries) or spinal surgery (spinal laminectomy).
  • Systemic diseases like cardiovascular disease( unstable angina, uncontrolled cardiac arrhythmias) and metabolic diseases.
  • Contraindication to exercises or usage of TENS (cardiac pacemaker, skin allergies to electrodes).

Trial locations and contacts

1 site in 1 country.

Pakistan1 site
  • University of Lahore Teaching Hospital

    Lahore, Punjab Province, 55150

Other trials in Pakistan

About this study

Official title: Comparative Effectiveness of Dynamic Stretching Versus Slider Neurodynamic Technique In Patients With Lumbar Radiculopathy : a Randomised Controlled Trail

This study will be a randomised clinical trial conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan. A total of 72 participants will be selected and randomly allocated into two treatment groups (36 participants in each group) using the lottery method. All screened and willing participants who meet the eligibility criteria will be assigned to either Group A or Group B.

Group A will receive dynamic stretching along with routine physiotherapy. Routine physiotherapy will include TENS (15 minutes), hot moist pack (10 minutes), soft tissue mobilisation (5-7 minutes), abdominal bracing, pelvic tilt, and alternate leg extension exercises. The dynamic stretching part will include the slump stretch, cat-camel stretch, hamstring sweeps, child pose stretch, and overhead lateral stretch. Each stretch will be performed in 2 sets of 15-20 repetitions with 1-minute rest between sets. Treatment will be provided four times per week for 6 weeks.

Read more

Group B will receive slider neurodynamic mobilisation along with the same routine physiotherapy protocol as group A. Slider neurodynamic mobilisation will be performed in the slump position, sitting at the edge of the plinth with the thighs parallel to each other and arms crossing behind the back. The examiner asked the patient to move actively and conversely from a position of neck and trunk flexion, knee flexion, and plantar flexion, to a position of neck and trunk extension, knee extension, and ankle dorsiflexion with 3 sets of 1-minute sliders and 1-minute rest between sets. Treatment will be provided four times per week for 6 weeks.

All participants will undergo assessments at baseline, at the end of the 3rd week, and at the end of the 6th week.

Read the detailed description
  • Screening Participants who meet the inclusion criteria was recruited using a convenience sampling technique. This involves selecting participants who are readily available to participate in the study.
  • Allocation Eligible participants were screened and informed about the study, including its purpose, procedures, potential risks, and benefits. Informed consent was obtained from each participant prior to their formal enrollment in the study.
  • Randomization:

Following the baseline assessment, the randomization was conducted using the Online Randomizer tool (https://www.randomizer.org/). By specifying the group numbers, the number of participants per group, and the total number of participants, unique identification numbers were generated for each participant.

  • Blindness: This study was single-blinded; the patients were kept blinded about the study and were not informed about the exercise protocol they received.
  • Intervention After taking consent, participants was selected based on the inclusion criteria. Sample of 72 was then be randomly divided into two groups.

All participants received a 35-minute treatment session, 4 days per week for 6 weeks, consisting of 15 minutes of routine physiotherapy and 20 minutes of a specific intervention:

Group A (Dynamic Stretching): Routine physiotherapy included TENS (70 Hz, 100 microseconds) for 15 minutes, hot moist packs for 10 minutes, and core strengthening (pelvic tilts and leg extensions). The main intervention was 20 minutes of dynamic stretching, including the slump stretch(The patient performed a slump stretch, seated with knees bent, extending one leg at a time while flexing the trunk forward to stretch the lumbar nerve roots), cat and camel(The patient alternated between spinal flexion and extension while on hands and knees.), hamstring sweeps(The patient performed dynamic hamstring stretches, sweeping the leg forward and back to increase flexibility in the posterior chain.), child's pose, and overhead lateral stretches(The patient performed a side stretch to target the quadratus lumborum and obliques, releasing tension from the side of the back.). Each exercise was performed for 4 minutes in 2 sets of 10-15 repetitions with 1 minute rest interval.

Group B (Slider Neurodynamic Technique): Routine physiotherapy matched Group A but included 5 minutes of soft tissue mobilization. The main intervention was the Slider Neurodynamic Mobilization (NDM). Patients were seated and performed rhythmic movements: moving from neck/trunk flexion and knee flexion to neck/trunk extension and knee extension. This movement is designed to "slide" the nerve through the spinal canal without over-tensioning it. This was performed in 3 sets of 1-minute intervals.

Clinical assessments for pain (NPRS), disability (MODI), and flexibility (MMST) were recorded at baseline, the 3rd week, and the 6th week to compare the efficacy of the two protocols.

Being tested
Dynamic stretching, slider neurodynamic mobilization, Routine physiotherapy
Keywords
lumbar radiculopathy, sciatica
Medical subject headings
Radiculopathy, Sciatica

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Dynamic stretchingOther

    Dynamic stretching protocol will include:

    • Slump Stretch (4 minutes): The patient performed a slump stretch, seated with knees bent, extending one leg at a time while flexing the trunk forward to stretch the lumbar nerve roots.
    • Cat and Camel Stretch (4 minutes): The patient alternated between spinal flexion and extension while on hands and knees.
    • Hamstring Sweeps (4 minutes): The patient performed dynamic hamstring stretches, sweeping the leg forward and back to increase flexibility in the posterior chain.
    • Child's Pose Stretch (4 minutes): The patient performed a child's pose stretch to improve flexibility in the lower back and hips.
    • Overhead Lateral Stretch (4 minutes): The patient performed a side stretch to target the quadratus lumborum and obliques, releasing tension from the side of the back.

    Each dynamic stretch will be performed as follows:

    • 2 sets of 10-15 repetitions
    • 1-minute rest between sets
    • Performed 3 sessions/week for 6 weeks
  • slider neurodynamic mobilizationOther

    Performed in the slump sitting position. Participants move from neck and trunk flexion with knee flexion and plantar flexion toward neck and trunk extension with knee extension and ankle dorsiflexion. The protocol consists of 3 sets of 1-minute slider movements, each followed by 1 minute of rest.

  • Routine physiotherapyOther

    TENS: Conventional Transcutaneous Electrical Nerve Stimulation was applied for 15 minutes (70 Hz frequency, 100 μs pulse width). Two 40×40 mm electrodes were positioned in a crossed pattern bilaterally over the lumbosacral region. A hot moist pack was applied to the lumbosacral and gluteal regions for 10 minutes in prone lying.Strengthening and Stabilization Exercises:

    Pelvic tilts were performed in crook-lying with 10-15 second holds. Alternate leg extensions were performed in prone with 10-second holds. Quadriceps and hip adductor/abductor strengthening were completed using isometric contractions (e.g., pillow squeeze)..All exercises were performed in 2 sets of 15-20 repetitions with 1 min rest. and lumbar traction.

Study groups in NCT07384832
Study groupRoleWhat they receive
Dynamic Stretching + Routine PhysiotherapyExperimentalParticipants in this group will receive Dynamic stretching Includes slump stretch, cat and camel, hamstring sweeps, child pose, and overhead lateral stretch. Protocol: 2 sets of 10-15 repetitions for 4 minutes with 1-minute rest intervals
Receives: Other: Dynamic stretching; Other: Routine physiotherapy
Slider Neurodynamic Mobilization + Routine PhysiotherapyExperimentalParticipants in this arm will receive Slider Neurodynamic Mobilization (NDM) along with routine physiotherapy. NDM slider techniques will be performed in the slump position according to a standardised protocol ( the patient to move actively and conversely from a position of neck and trunk flexion, knee flexion, and plantar flexion, to a position of neck and trunk extension, knee extension, and ankle dorsiflexion ) protocol: 3 sets of 1 minute slider movement with 1 minute rest interval
Receives: Other: slider neurodynamic mobilization; Other: Routine physiotherapy

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Pain Intensity (NPRS)

    Pain Intensity will n=be measured using the numeric pain rating scale (NPRS) , where participants rate their pain on a scale from 0 to 10 (0= no pain, 10= worst possible pain). the scale will be used to assess changes in pain levels over the duration of the intervention.

    Measured: baseline, 3rd week, 6th week

Secondary outcomes (2)
  1. Functional Disability (Modified Oswestry Disability Index -MODI)

    Functional disability will be measured using the modified oswestry low back pain disability index, a validated questionnaire assessing limitations in everyday activities. scores range from 0-100 % with higher scores indicating greater disability. the measure will be used to determine changes in functional ability.

    Measured: baseline,3rd week, 6th week

  2. Lumbar Flexion Range of Motion (Modified-Modified Schober Test - MMST)

    Lumbar flexion range of motion will be assessed using the Modified-Modified Schober Test (MMST). The test measures the change in distance between two points on the lumbar spine during forward flexion. Increased distance indicates improved lumbar mobility.

    Measured: baseline, 3rd week, 6th week

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted3 Feb 2026
  2. Study start20 Jun 2025
  3. Primary completion30 Jan 2026
  4. Study completion10 Feb 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
72 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07384832
Sponsor's protocol ID
UOL/IREB/25/09/0043
Status last verified
Feb 2026
First submitted
26 Jan 2026
Last updated
14 Apr 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Shaheen HM, Belgen Kaygisiz B. Comparison of different treatment positions of nerve slider technique for patients with low back pain: a randomized control trial. Eur J Phys Rehabil Med. 2025 Feb;61(1):82-92. doi: 10.23736/S1973-9087.24.08541-1. Epub 2025 Jan 28.

    PubMed 39873676
  • Nahid ZBS, Ahmed F, Islam MF, Rahman Z, Haque MF, Arju A, Islam MR, Moula G, Sarker B. Effectiveness of Shacklock's Neural Mobilization for Acute and Sub-Acute Lumbar Disc Prolapsed: A Randomized Controlled Trial. Health Sci Rep. 2025 May 26;8(5):e70872. doi: 10.1002/hsr2.70872. eCollection 2025 May.

    PubMed 40432703
  • de Ridder R, De Blaiser C, Verrelst R, De Saer R, Desmet A, Schuermans J. Neurodynamic sliders promote flexibility in tight hamstring syndrome. Eur J Sport Sci. 2020 Aug;20(7):973-980. doi: 10.1080/17461391.2019.1675770. Epub 2019 Oct 22.

    PubMed 31578925
  • Danazumi MS, Bello B, Yakasai AM, Kaka B. Two manual therapy techniques for management of lumbar radiculopathy: a randomized clinical trial. J Osteopath Med. 2021 Feb 26;121(4):391-400. doi: 10.1515/jom-2020-0261.

    PubMed 33705612
  • Ghaderi Niri H, Ghanavati T, Mostafaee N, Salahzadeh Z, Divandari A, Adigozali H, Ahadi J. Oswestry Disability Index, Roland-Morris Disability Questionnaire, and Quebec Back Pain Disability Scale: Responsiveness and Minimal Clinically Important Changes in Iranian People with Lumbar Disc Herniation Following Physiotherapy. Arch Bone Jt Surg. 2024;12(1):58-65. doi: 10.22038/ABJS.2023.72246.3366.

    PubMed 38318303

Questions about this trial

What is this clinical trial studying?

A study testing Dynamic stretching, slider neurodynamic mobilization and Routine physiotherapy in people with Lumbar Radiculopathy, run by University of Lahore at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 14 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Pain Intensity (NPRS) (time frame: baseline, 3rd week, 6th week). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07384832, which also lists 5 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Apr 2026.

Free account

Log in to keep searching

You’ve used your 3 free searches. AzTrials is free: log in or create a free account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in