VATSNCT07395661
Comparison Of Analgesic Methods İn Video-Assisted Thoracoscopic Surgery
A study testing Ultrasound guided serratus anterior plane block and Ultrasound guided serratus posterior superior intercostal plane block in people with VATS and Pain Management, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Introduction and Objective: The aim of this study is to compare the postoperative analgesic efficacy of the serratus anterior plane… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- VATS, Pain Management, Plane Blocks
- What is being tested?
- Ultrasound guided serratus anterior plane block and Ultrasound guided serratus posterior superior intercostal plane block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 13 Jan 2025to 13 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patient aged between 18 and 65 years ASA physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) Provided written information consent
Who cannot join
- History of allergy or toxicity to local anesthetic agents
- Known or suspected coagulopathy
- Infection at the site of block injection
- Advanced organ failure
- Diagnosed mental retardation
- Pregnancy
Show all 11Show fewer
- Pediatric patients
- History of thoracotomy
- Requirement for postoperative intubation
- Emergency surgery
- Refusal to participate in the study
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
University of Health Siences Gazi Yasargil Training and Research Hospital
Diyarbakır, Kayapınar, 21100
About this study
Official title: Comparıson Of The Postoperatıve Analgesıc Effıcacy Of Serratus Anterıor Plane Block And Serratus Posterıor Superıor Intercostal Plane Block Performed Under Ultrasonography Guıdance In Vıdeo-Assısted Thoracoscopıc Surgery
Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Introduction and Objective: The aim of this study is to compare the postoperative analgesic efficacy of the serratus anterior plane block and serratus posterior superior intercostal plane block performed under ultrasonography guidance in patients undergoing video-assisted thoracoscopic surgery.
Patients with ASA grades I-III, aged 18-65, will be included in the study. Standard general anesthesia will be administered to the patients. Postoperative analgesia evaluation will be conducted using VAS and NRS scores at specific time points after surgery Additional analgesic requirements and patient satisfaction will be recorded.
- Conditions
- VATS, Pain Management, Plane Blocks
- Being tested
- Ultrasound guided serratus anterior plane block, Ultrasound guided serratus posterior superior intercostal plane block
- Keywords
- VATS, Pain Management, Plane Blocks, SPSIPB, SAPB
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound guided serratus anterior plane blockProcedure or surgery
Also called serratus anterior plane block
Ultrasound-guided serratus anterior plane block was performed at the 4th intercostal level in the mid-axillary line using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the latissumus dorsi and serratus anterior muscles (unilateral)
Ultrasound guided serratus posterior superior intercostal plane blockProcedure or surgery
Also called Serratus posterior superior intercostal plane block
Ultrasound-guided serratus posterior superior intercostal plane block was performed using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the serratus posterior superior and intercostal muscles at the 3rd rib level via a posterior approach (unilateral)
| Study group | Role | What they receive |
|---|---|---|
| SERRATUS ANTERİOR PLANE BLOCK | Experimental | Participants received an ultrasound-guieded serratus anterior plane block (SAPB) Receives: Procedure: Ultrasound guided serratus anterior plane block |
| SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK | Experimental | Participants received an ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB) Receives: Procedure: Ultrasound guided serratus posterior superior intercostal plane block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pain intensity
Postoperative pain intensity was assessed using the Visual Analog Scale (VAS) where 0 indicates no pain and 10 indicates the worst imaginable pain
Measured: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Secondary outcomes (5)
Postoperative pain intensity assessed by Numeric Rating Scale (NRS)
Postoperative pain intensity will be assessed using the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst pain imaginable)
Measured: 30 minutes, 1, 4, 8, 12, 24 hours after surgery
Total 24-hour tramadol consumption
Total amount of rescue tramadol administered within the first 24 postoperative hours, recorded in milligrams
Measured: 24 hours after surgery
Rescue analgesia requirement
Proportion of patients requiring rescue analgesia (intravenous tramadol) at each postoperative assessment time point
Measured: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Adverse events
Incidence of local anesthetic systemic toxicity, pneumothorax, hypotension, nausea/vomiting, and block-related complications
Measured: Within 24 hours after surgery
Dynamic (movement-associated) postoperative pain intensity
Postoperative pain intensity during movement/coughing was assessed using the Visual Analog Scale (VAS), distinct from the primary outcome which assessed pain at rest (static VAS)
Measured: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Feb 2026
- Study start13 Jan 2025
- Primary completion11 Jul 2025
- Study completion13 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for VATSStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Renim Yüksel, Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07395661
- Sponsor's protocol ID
- 225
- Status last verified
- Jan 2026
- First submitted
- 24 Jan 2026
- Last updated
- 12 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparıson Of The Postoperatıve Analgesıc Effıcacy Of Serratus Anterıor Plane Block And Serratus Posterıor Superıor Intercostal Plane Block Performed Under Ultrasonography Guıdance In Vıdeo-Assısted Thoracoscopıc Surgery
- ClinicalTrials.gov ID
- NCT07395661
- Acronym / sponsor ID
- 225
- Conditions
- VATS, Pain Management, Plane Blocks
- Keywords
- VATS, Pain Management, Plane Blocks, SPSIPB, SAPB
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalUniversity, hospital or other
- Study start
- 13 Jan 2025 (actual)
- Primary completion
- 11 Jul 2025 (actual)
- Study completion
- 13 Oct 2025 (actual)
- First posted
- 9 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Introduction and Objective: The aim of this study is to compare the postoperative analgesic efficacy of the serratus anterior plane block and serratus posterior superior intercostal plane block performed under ultrasonography guidance in patients undergoing video-assisted thoracoscopic surgery.
Patients with ASA grades I-III, aged 18-65, will be included in the study. Standard general anesthesia will be administered to the patients. Postoperative analgesia evaluation will be conducted using VAS and NRS scores at specific time points after surgery Additional analgesic requirements and patient satisfaction will be recorded.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| SERRATUS ANTERİOR PLANE BLOCK | Experimental | Procedure: Ultrasound guided serratus anterior plane blockParticipants received an ultrasound-guieded serratus anterior plane block (SAPB) |
| SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK | Experimental | Procedure: Ultrasound guided serratus posterior superior intercostal plane blockParticipants received an ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB) |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Patient aged between 18 and 65 years ASA physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) Provided written information consent
Key exclusion criteria (11 listed)
- History of allergy or toxicity to local anesthetic agents
- Known or suspected coagulopathy
- Infection at the site of block injection
- Advanced organ failure
- Diagnosed mental retardation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound guided serratus anterior plane blockAlso: serratus anterior plane blockUltrasound-guided serratus anterior plane block was performed at the 4th intercostal level in the mid-axillary line using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the latissumus dorsi and serratus anterior muscles (unilateral) | Procedure or surgery | SERRATUS ANTERİOR PLANE BLOCK |
| Ultrasound guided serratus posterior superior intercostal plane blockAlso: Serratus posterior superior intercostal plane blockUltrasound-guided serratus posterior superior intercostal plane block was performed using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the serratus posterior superior and intercostal muscles at the 3rd rib level via a posterior approach (unilateral) | Procedure or surgery | SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK |
Primary outcome
Postoperative pain intensity
Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Postoperative pain intensity was assessed using the Visual Analog Scale (VAS) where 0 indicates no pain and 10 indicates the worst imaginable pain
5 secondary outcomes
Postoperative pain intensity assessed by Numeric Rating Scale (NRS)
Time frame: 30 minutes, 1, 4, 8, 12, 24 hours after surgery
Total 24-hour tramadol consumption
Time frame: 24 hours after surgery
Rescue analgesia requirement
Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Adverse events
Time frame: Within 24 hours after surgery
Dynamic (movement-associated) postoperative pain intensity
Time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound guided serratus anterior plane block and Ultrasound guided serratus posterior superior intercostal plane block in people with VATS and Pain Management, run by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative pain intensity (time frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Aug 2026; AzTrials last refreshed its copy on 6 Nov 2026.