BiofilmNCT07408245
Effects of Biocidin on Oral Biofilms
A study testing Biocidin Liquid in people with Biofilm, run by OvationLab at 1 site in United States.
Trial summary
The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of Biocidin liquid on oral biofilms as assessed by SimplyPERIO… Read more about this study
- Who is it for?
- Ages 25 years and olderHealthy volunteers can take part
- Conditions the study is for
- Biofilm
- What is being tested?
- Biocidin Liquid
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteUnited States
- Study dates
- 17 Feb 2026to 30 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adult females or males age ≥ 25 years
- Ability to read and speak English
- Willingness to take use oral Biocidin as directed for two weeks
- Willingness not to change any other oral health practices for two weeks
- Willingness not to change dietary habits for two weeks
- Willingness to perform a SimplyPERIO oral microbiome test before and after the two-week Biocidin intervention
Who cannot join
- Current use of oral Biocidin or botanical mouthwash
- Use of antibiotics within the past 30 days
- Current use of fixed intraoral orthodontic appliances (e.g., dental braces, fixed retainers, or similar devices)
- Known allergies to any of the ingredients in the product
- Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
- Participants unable to provide consent
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Prospective Human Study Evaluating the Effects of Biocidin Liquid on Oral Biofilms: An Open-label Pilot Study
The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of Biocidin liquid on oral biofilms as assessed by SimplyPERIO (Spectrum Solutions, Salt Lake City, UT).
- Conditions
- Biofilm
- Being tested
- Biocidin Liquid
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Biocidin LiquidDietary supplement
Broad-spectrum botanical liquid formula
| Study group | Role | What they receive |
|---|---|---|
| Biocidin Liquid | Experimental | Broad-spectrum botanical liquid formula Receives: Dietary Supplement: Biocidin Liquid |
What is being measured
The primary outcome is the main question the study is designed to answer.
Oral Biofilm Microorganisms
SimplyPERIO - Oral biofilm microorganism test results are categorized as "low", "medium", and "high".
Measured: Measured at baseline and conclusion of 2-week study
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Feb 2026
- Study start17 Feb 2026
- Primary completion30 May 2026
- Study completion30 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for BiofilmStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- OvationLab
- Sponsor type
- Research network
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07408245
- Sponsor's protocol ID
- BIO-003
- Status last verified
- Jul 2026
- First submitted
- 6 Feb 2026
- Last updated
- 29 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: IPD will be made available on a public repository
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prospective Human Study Evaluating the Effects of Biocidin Liquid on Oral Biofilms: An Open-label Pilot Study
- ClinicalTrials.gov ID
- NCT07408245
- Acronym / sponsor ID
- BIO-003
- Conditions
- Biofilm
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- OvationLabResearch network
- Study start
- 17 Feb 2026 (actual)
- Primary completion
- 30 May 2026 (actual)
- Study completion
- 30 May 2026 (actual)
- First posted
- 13 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of Biocidin liquid on oral biofilms as assessed by SimplyPERIO (Spectrum Solutions, Salt Lake City, UT).
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Biocidin Liquid | Experimental | Dietary Supplement: Biocidin LiquidBroad-spectrum botanical liquid formula |
Who may qualify
- Ages
- 25 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Adult females or males age ≥ 25 years
- Ability to read and speak English
- Willingness to take use oral Biocidin as directed for two weeks
- Willingness not to change any other oral health practices for two weeks
- Willingness not to change dietary habits for two weeks
Key exclusion criteria (6 listed)
- Current use of oral Biocidin or botanical mouthwash
- Use of antibiotics within the past 30 days
- Current use of fixed intraoral orthodontic appliances (e.g., dental braces, fixed retainers, or similar devices)
- Known allergies to any of the ingredients in the product
- Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Biocidin LiquidBroad-spectrum botanical liquid formula | Dietary supplement | Biocidin Liquid |
Primary outcome
Oral Biofilm Microorganisms
Time frame: Measured at baseline and conclusion of 2-week study
SimplyPERIO - Oral biofilm microorganism test results are categorized as "low", "medium", and "high".
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2026.
- Individual participant dataSharing planned: Yes. IPD will be made available on a public repository
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Biocidin Liquid in people with Biofilm, run by OvationLab at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Oral Biofilm Microorganisms (time frame: Measured at baseline and conclusion of 2-week study). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2026.