Peripheral Nerve BlockNCT07442188
Comparison of Postoperative Analgesic Effects of Quadro-iliac Plane Block and Transversus Abdominis Plane Blocks in Inguinal Hernia Surgery
A study testing TAPB and QIPB in people with Peripheral Nerve Block and Pain Management, run by Ankara Etlik City Hospital at 1 site in Turkey (Türkiye).
Trial summary
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide. Despite being classified as a minor surgical intervention, moderate to severe postoperative pain is reported in approximately 60% of patients. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Peripheral Nerve Block, Pain Management, Hernia, Inguinal
- What is being tested?
- TAPB and QIPB
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 2 Jun 2026to 19 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients aged between 18 and 65 years
- Patients with an American Society of Anesthesiologists (ASA) physical status classification of I-III.
- Patients with a body mass index (BMI) between 18 and 30 kg/m².
- Patients scheduled to undergo unilateral inguinal hernia repair under general anesthesia in the operating room.
Who cannot join
- Patients younger than 18 years or older than 65 years.
- Patients with an ASA physical status classification of IV or higher.
- Patients with advanced comorbidities.
- Patients with a history of bleeding diathesis.
- Patients with infection at the site of the planned procedure.
- Patients with a BMI below 18 kg/m² or above 30 kg/m².
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Ankara Etlik City Hospital
Ankara, Yenimahalle\Ankara, 06170
İbrahim MD Topcu, 05437860316, ibrahimtpc78@gmail.com
Musa Assoc.Prof Zengin, 00905307716235, musazengin@gmail.com
About this study
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide. Despite being classified as a minor surgical intervention, moderate to severe postoperative pain is reported in approximately 60% of patients. In a subset of these patients, acute postoperative pain may persist and evolve into chronic post-surgical inguinal pain, significantly affecting quality of life.
In recent years, beyond the use of systemic intravenous analgesics, ultrasound-guided fascial plane blocks have been increasingly incorporated into multimodal analgesia protocols with the aim of reducing postoperative opioid consumption and improving pain control. However, the current literature does not provide definitive evidence regarding the superiority of one block technique over another in this surgical population.
The primary objective of the present study is to compare the analgesic efficacy of the Quadro-iliac Plane Block (QIPB) and the transversus abdominis plane block (TAPB) in patients undergoing inguinal hernia repair.
- Conditions
- Peripheral Nerve Block, Pain Management, Hernia, Inguinal
- Being tested
- TAPB, QIPB
- Keywords
- Quadro Iliac Plane Block, Transversus Abdominis Plane Block
- Medical subject headings
- Agnosia, Hernia, Inguinal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
TAPBProcedure or surgery
Patients will undergo TAPB procedure using 30 ml of 0.25% bupivacaine under ultrasound guidance.
QIPBProcedure or surgery
Patients will undergo QIPB procedure using 30 ml of 0.25% bupivacaine under ultrasound guidance.
| Study group | Role | What they receive |
|---|---|---|
| TAPB | Active comparator | After the patients were placed under observation, positioned in the supine position, and appropriate area sterilization was performed, TAPB was administered to the patients with 30 ml of 0.25% bupivacaine under ultrasound guidance. Receives: Procedure: TAPB |
| QIPB | Active comparator | After the patients were placed under observation, positioned in the lateral decubitus position, and appropriate area sterilization was performed, QIPB was administered to the patients with 30 ml of 0.25% bupivacaine under ultrasound guidance. Receives: Procedure: QIPB |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Score
Pain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) at rest and when coughing. Pain assessment will be made at 0, 1, 6, 12, 18, and 24 hours after surgery.
Measured: Up to 24 hours
Secondary outcomes (1)
Patient Satisfaction
Quality of recovery-15 (QoR-15) score was used as the satisfaction score. The patient-reported Turkish QoR-15 score includes 15 questions that evaluate the patient's postoperative recovery. The QoR-15 score is grouped under two groups, A and B. A high QoR-15 score, a score between 0 (poor) and 10 (excellent) for each item, and a total score of 150 indicate better quality of recovery.
Measured: 24th hour
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Mar 2026
- Study start2 Jun 2026
- Primary completion5 Oct 2026 (estimated)
- Study completion19 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Peripheral Nerve BlockStudies of the same condition, open and under way.
- More trials run by Ankara Etlik City HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ankara Etlik City Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, İbrahim Topcu, Ankara Etlik City Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07442188
- Sponsor's protocol ID
- AEŞH-EK-2026-017
- Status last verified
- Jun 2026
- First submitted
- 24 Feb 2026
- Last updated
- 3 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Postoperative Analgesic Effects of Quadro-iliac Plane Block and Transversus Abdominis Plane Blocks in Inguinal Hernia Surgery
- ClinicalTrials.gov ID
- NCT07442188
- Acronym / sponsor ID
- AEŞH-EK-2026-017
- Conditions
- Peripheral Nerve Block, Pain Management, Hernia, Inguinal
- Keywords
- Quadro Iliac Plane Block, Transversus Abdominis Plane Block
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Ankara Etlik City HospitalOther government
- Study start
- 2 Jun 2026 (actual)
- Primary completion
- 5 Oct 2026 (estimated)
- Study completion
- 19 Oct 2026 (estimated)
- First posted
- 2 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide. Despite being classified as a minor surgical intervention, moderate to severe postoperative pain is reported in approximately 60% of patients. In a subset of these patients, acute postoperative pain may persist and evolve into chronic post-surgical inguinal pain, significantly affecting quality of life.
In recent years, beyond the use of systemic intravenous analgesics, ultrasound-guided fascial plane blocks have been increasingly incorporated into multimodal analgesia protocols with the aim of reducing postoperative opioid consumption and improving pain control. However, the current literature does not provide definitive evidence regarding the superiority of one block technique over another in this surgical population.
The primary objective of the present study is to compare the analgesic efficacy of the Quadro-iliac Plane Block (QIPB) and the transversus abdominis plane block (TAPB) in patients undergoing inguinal hernia repair.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| TAPB | Active comparator | Procedure: TAPBAfter the patients were placed under observation, positioned in the supine position, and appropriate area sterilization was performed, TAPB was administered to the patients with 30 ml of 0.25% bupivacaine under ultrasound guidance. |
| QIPB | Active comparator | Procedure: QIPBAfter the patients were placed under observation, positioned in the lateral decubitus position, and appropriate area sterilization was performed, QIPB was administered to the patients with 30 ml of 0.25% bupivacaine under ultrasound guidance. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients aged between 18 and 65 years
- Patients with an American Society of Anesthesiologists (ASA) physical status classification of I-III.
- Patients with a body mass index (BMI) between 18 and 30 kg/m².
- Patients scheduled to undergo unilateral inguinal hernia repair under general anesthesia in the operating room.
Key exclusion criteria (6 listed)
- Patients younger than 18 years or older than 65 years.
- Patients with an ASA physical status classification of IV or higher.
- Patients with advanced comorbidities.
- Patients with a history of bleeding diathesis.
- Patients with infection at the site of the planned procedure.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| TAPBPatients will undergo TAPB procedure using 30 ml of 0.25% bupivacaine under ultrasound guidance. | Procedure or surgery | TAPB |
| QIPBPatients will undergo QIPB procedure using 30 ml of 0.25% bupivacaine under ultrasound guidance. | Procedure or surgery | QIPB |
Primary outcome
Pain Score
Time frame: Up to 24 hours
Pain will be assessed using a visual analog scale from 0 mm (no pain) to 100 mm (worst pain) at rest and when coughing. Pain assessment will be made at 0, 1, 6, 12, 18, and 24 hours after surgery.
1 secondary outcome
Patient Satisfaction
Time frame: 24th hour
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing TAPB and QIPB in people with Peripheral Nerve Block and Pain Management, run by Ankara Etlik City Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ibrahim Topcu, MD (+905437860316, ibrahimtpc78@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Score (time frame: Up to 24 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jun 2026.