Catheterization, Central VenousNCT07459088
Central Venous Catheterization in Children: Jugulo-subclavian Venous Confluence Versus Internal Jugular Vein
A study testing central venous catheterization in people with Catheterization, Central Venous, run by Tunis University at 1 site in Tunisia.
Trial summary
The goal of this study was to compare ultrasound-guided central venous catheterization via the IJV to the JSVC using the supraclavicular approach in children. The main questions it aims to answer are: 1. Read more about this study
- Who is it for?
- Ages 1 month to 14 years
- Conditions the study is for
- Catheterization, Central Venous
- What is being tested?
- central venous catheterization
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 88 participants
- Where
- 1 siteTunisia
- Study dates
- 17 Dec 2023to 30 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 month to 14 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Children aged 1 month to 14 years, admitted to the pediatric intensive care unit of the anesthesiology and critical care department at Béchir Hamza Children's Hospital in Tunis, or scheduled for major elective surgery under general anesthesia requiring central venous catheter placement.
Who cannot join
- Patients in whom ultrasound revealed a thrombotic formation in the vein.
- Patients for whom the vein could not be adequately visualized on ultrasound
Trial locations and contacts
1 site in 1 country.
About this study
The goal of this study was to compare ultrasound-guided central venous catheterization via the IJV to the JSVC using the supraclavicular approach in children. The main questions it aims to answer are:
- Are ultrasound-guided central venous catheterization via the internal jugular vein (IJV) and via the jugular-supraclavicular vein (JSVC) using the supraclavicular approach equivalent in terms of procedural efficacy (e.g., success rate, time to cannulation) in children?
- Are these two techniques comparable in terms of safety (e.g., complication rates, adverse events) in pediatric patients?
- Conditions
- Catheterization, Central Venous
- Being tested
- central venous catheterization
- Keywords
- Central venous catheterization, jugular veins, subclavian vein, ultrasound, pediatric anesthesia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
central venous catheterizationProcedure or surgery
ultrasound guided central venous catheterization in children
| Study group | Role | What they receive |
|---|---|---|
| IVJ group | Other | Group undergoing catheterization of the internal jugular vein using an out-of-plane technique Receives: Procedure: central venous catheterization |
| JSVC group | Other | Group undergoing catheterization of the jugulosubclavian confluent via the supraclavicular in-plane technique Receives: Procedure: central venous catheterization |
What is being measured
The primary outcome is the main question the study is designed to answer.
first-attempt Success rate
Obtaining blood reflux from the target vein on the first attempt
Measured: From the day of randomization until radiographic confirmation of central venous catheter position, assessed up to 6 hours.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Mar 2026
- Study start17 Dec 2023
- Primary completion30 Apr 2025
- Study completion30 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Catheterization, Central VenousStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 88 participants (actual)
Sponsor and investigators
- Lead sponsor
- Tunis University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mehdi Trifa, Tunis University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07459088
- Sponsor's protocol ID
- 072025
- Status last verified
- Jul 2025
- First submitted
- 9 Feb 2026
- Last updated
- 9 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Central Venous Catheterization in Children: Jugulo-subclavian Venous Confluence Versus Internal Jugular Vein
- ClinicalTrials.gov ID
- NCT07459088
- Acronym / sponsor ID
- 072025
- Conditions
- Catheterization, Central Venous
- Keywords
- Central venous catheterization, jugular veins, subclavian vein, ultrasound, pediatric anesthesia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 88 participants (actual)
- Lead sponsor
- Tunis UniversityUniversity, hospital or other
- Study start
- 17 Dec 2023 (actual)
- Primary completion
- 30 Apr 2025 (actual)
- Study completion
- 30 Apr 2025 (actual)
- First posted
- 9 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study was to compare ultrasound-guided central venous catheterization via the IJV to the JSVC using the supraclavicular approach in children. The main questions it aims to answer are:
- Are ultrasound-guided central venous catheterization via the internal jugular vein (IJV) and via the jugular-supraclavicular vein (JSVC) using the supraclavicular approach equivalent in terms of procedural efficacy (e.g., success rate, time to cannulation) in children?
- Are these two techniques comparable in terms of safety (e.g., complication rates, adverse events) in pediatric patients?
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| IVJ group | Other | Procedure: central venous catheterizationGroup undergoing catheterization of the internal jugular vein using an out-of-plane technique |
| JSVC group | Other | Procedure: central venous catheterizationGroup undergoing catheterization of the jugulosubclavian confluent via the supraclavicular in-plane technique |
Who may qualify
- Ages
- 1 month to 14 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (1 listed)
- Children aged 1 month to 14 years, admitted to the pediatric intensive care unit of the anesthesiology and critical care department at Béchir Hamza Children's Hospital in Tunis, or scheduled for major elective surgery under general anesthesia requiring central venous catheter placement.
Key exclusion criteria (2 listed)
- Patients in whom ultrasound revealed a thrombotic formation in the vein.
- Patients for whom the vein could not be adequately visualized on ultrasound
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| central venous catheterizationultrasound guided central venous catheterization in children | Procedure or surgery | IVJ group, JSVC group |
Primary outcome
first-attempt Success rate
Time frame: From the day of randomization until radiographic confirmation of central venous catheter position, assessed up to 6 hours.
Obtaining blood reflux from the target vein on the first attempt
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing central venous catheterization in people with Catheterization, Central Venous, run by Tunis University at 1 site in Tunisia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Tunisia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
first-attempt Success rate (time frame: From the day of randomization until radiographic confirmation of central venous catheter position, assessed up to 6 hours.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Mar 2026.