Meal TimingNCT07545330
Effect of Circadian Timing of a Standardized Meal on Postprandial Glucose Response in Healthy Adults
A study testing Standardized Test Meal in people with Meal Timing and Postprandial Glucose, run by King Faisal University at 1 site in Saudi Arabia.
Trial summary
This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults. Postprandial glucose will be assessed using the incremental area under the curve (iAUC) over 120 minutes. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Meal Timing, Postprandial Glucose, Glycemic Response to Feeding in Healthy Participants
- What is being tested?
- Standardized Test Meal
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteSaudi Arabia
- Study dates
- 21 Apr 2026to 15 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Healthy adults aged 18 years and older
- Able and willing to provide informed consent
- Able to comply with study procedures
Who cannot join
- Diagnosis of diabetes or any metabolic disorder affecting glucose regulation
- Use of any medications
- Pregnant or breastfeeding women
- Night shift workers or individuals with irregular sleep patterns
Trial locations and contacts
1 site in 1 country.
Saudi Arabia1 site
King Faisal University
Al-Ahsa, Eastern Province, 31982
About this study
This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults. Postprandial glucose will be assessed using the incremental area under the curve (iAUC) over 120 minutes.
- Being tested
- Standardized Test Meal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Standardized Test MealOther
The standardized test meal provided 50 g of carbohydrates of weighed portions of white bread and jam, served with 200 mL of water.
| Study group | Role | What they receive |
|---|---|---|
| Morning Meal Condition | Experimental | Participants will consume a standardized test meal in the morning following an overnight fasting period of at least 8 hours. Postprandial glucose will be measured over 120 minutes. Receives: Other: Standardized Test Meal |
| Evening Meal Condition | Experimental | Participants will consume the same standardized test meal in the evening following a standardized fasting period of at least 8 hours prior to the test meal. Postprandial glucose will be measured over 120 minutes. Receives: Other: Standardized Test Meal |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incremental Area Under the Curve (iAUC) for Postprandial Glucose
The primary objective of this study is to investigate the effect of circadian timing of a standardized test meal (morning versus evening consumption) on postprandial glucose response in healthy adults, assessed as the incremental area under the curve (iAUC) for capillary blood glucose over 120 minutes following meal consumption
Measured: Baseline to 120 minutes after consumption of the standardized test meal
Secondary outcomes (3)
Peak Postprandial Glucose (Morning vs Evening)
Peak capillary blood glucose concentration measured within 120 minutes after consumption of the standardized test meal, under morning and evening conditions
Measured: Baseline to 120 minutes after consumption of the standardized test meal
Time to Peak Glucose (Morning vs Evening)
Time required to reach peak capillary blood glucose concentration following meal consumption, under morning and evening conditions.
Measured: Baseline to 120 minutes after consumption of the standardized test meal
Postprandial Glucose Profile (Morning vs Evening)
Capillary blood glucose concentrations measured at predefined time points following consumption of the standardized test meal, under morning and evening conditions.
Measured: Baseline, 15, 30, 60, 90, and 120 minutes after consumption of the standardized test meal
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Apr 2026
- Study start21 Apr 2026
- Primary completion15 Jul 2026
- Study completion15 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Meal TimingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- King Faisal University
- Sponsor type
- University, hospital or other
- Collaborators
- Saudi Food and Drug Authority
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07545330
- Sponsor's protocol ID
- ETHICS3992
- Status last verified
- Sep 2026
- First submitted
- 16 Apr 2026
- Last updated
- 1 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: De-identified individual participant data (IPD) collected in this study will not be made publicly available. Data will be used for research purposes by the study investigators only
Study at a glance
From the registry record, last updated by the sponsor on 1 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Circadian Timing of a Standardized Meal on Postprandial Glucose Response in Healthy Adults
- ClinicalTrials.gov ID
- NCT07545330
- Acronym / sponsor ID
- ETHICS3992
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- King Faisal UniversityUniversity, hospital or other
- Collaborators
- Saudi Food and Drug Authority
- Study start
- 21 Apr 2026 (actual)
- Primary completion
- 15 Jul 2026 (actual)
- Study completion
- 15 Jul 2026 (actual)
- First posted
- 22 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults. Postprandial glucose will be assessed using the incremental area under the curve (iAUC) over 120 minutes.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Morning Meal Condition | Experimental | Other: Standardized Test MealParticipants will consume a standardized test meal in the morning following an overnight fasting period of at least 8 hours. Postprandial glucose will be measured over 120 minutes. |
| Evening Meal Condition | Experimental | Other: Standardized Test MealParticipants will consume the same standardized test meal in the evening following a standardized fasting period of at least 8 hours prior to the test meal. Postprandial glucose will be measured over 120 minutes. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Healthy adults aged 18 years and older
- Able and willing to provide informed consent
- Able to comply with study procedures
Key exclusion criteria (4 listed)
- Diagnosis of diabetes or any metabolic disorder affecting glucose regulation
- Use of any medications
- Pregnant or breastfeeding women
- Night shift workers or individuals with irregular sleep patterns
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Standardized Test MealThe standardized test meal provided 50 g of carbohydrates of weighed portions of white bread and jam, served with 200 mL of water. | Other | Evening Meal Condition, Morning Meal Condition |
Primary outcome
Incremental Area Under the Curve (iAUC) for Postprandial Glucose
Time frame: Baseline to 120 minutes after consumption of the standardized test meal
The primary objective of this study is to investigate the effect of circadian timing of a standardized test meal (morning versus evening consumption) on postprandial glucose response in healthy adults, assessed as the incremental area under the curve (iAUC) for capillary blood glucose over 120 minutes following meal consumption
3 secondary outcomes
Peak Postprandial Glucose (Morning vs Evening)
Time frame: Baseline to 120 minutes after consumption of the standardized test meal
Time to Peak Glucose (Morning vs Evening)
Time frame: Baseline to 120 minutes after consumption of the standardized test meal
Postprandial Glucose Profile (Morning vs Evening)
Time frame: Baseline, 15, 30, 60, 90, and 120 minutes after consumption of the standardized test meal
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Oct 2026.
- Individual participant dataSharing planned: No. De-identified individual participant data (IPD) collected in this study will not be made publicly available. Data will be used for research purposes by the study investigators only
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Standardized Test Meal in people with Meal Timing and Postprandial Glucose, run by King Faisal University at 1 site in Saudi Arabia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Saudi Arabia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incremental Area Under the Curve (iAUC) for Postprandial Glucose (time frame: Baseline to 120 minutes after consumption of the standardized test meal). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026.