Clinical trials: Meal Timing
Healthy Volunteers
Phase I Clinical Study of MWN109 Tablets in Healthy Chinese Participants
This is a randomized, double-blind, placebo-controlled, Phase 1 clinical study conducted in China to evaluate the safety, tolerability, pharmacokinetic (PK), and the effect of meal timing following single and multiple oral doses…
- Trial name
- NCT07787611
- Testing
- MWN109 tablet
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes
This study will test whether glucose sensor data can be used to identify the time of day when adults with prediabetes are most likely to have high blood sugar after meals.
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes or Diabetes
- Trial name
- CLOCK-PRIME (NCT07618663)
- Testing
- Phenotype-Guided Meal Timing and Postprandial Walking, Sleep Hygiene and Step-Count Advice
- Where
- Pakistan
- Volunteers
- 105 people
- Sponsor
- Shifa International Hospital
Meal Timing
Does Meal Timing Affect Energy Expenditure
The purpose of this study is to find out if meal timing affects calories burned and blood sugar levels.
- Trial name
- GRAZING (NCT02247076)
- Testing
- Grazing, Time-restricted feeding (early eating)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes, Obesity
Effect of Meal Timing in T2D on Hepatocytes SRIT1 and Clock Genes
This study is undertaken to explore in T2D, the effect of meal timing on serum induced SIRT1 and Clock Genes mRNA expression in cultured hepatocytes.
- Trial name
- Liver-CG (NCT04405895)
- Testing
- Breakfast Diet, Allday Diet
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Tel Aviv University
Obesity
Daytime vs. Delayed Eating Among Obese Individuals
The randomized, cross-over design study is designed to determine how timing of eating affects weight, adiposity, energy metabolism, and gene expression.
- Trial name
- NCT03354169
- Testing
- Eating Condition, No Intervention; withdrawn before randomization
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pre Diabetes
Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals
The purpose of this study is to investigate the effect of mango intake on metabolic and inflammatory responses relative to meals in individuals at risk of developing diabetes, as well as to understand how the beneficial compounds…
- Trial name
- MG3 (NCT06986161)
- Testing
- Mango, Control Beverage
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Healthy
Effect of Meal Composition and Timing on Evobrutinib Bioavailability
This study will evaluate the Pharmacokinetics (PK) of the Phase II tablet formulation of Evobrutinib under fasted conditions, within 30 minutes after start of a light meal, one hour prior to start of a low-fat meal, and 2 hours…
- Trial name
- NCT03934502
- Testing
- Evobrutinib
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Light Exposure, Meal Timing
Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms
The aim of this study is to determine the principal time cue (light or meals) for resetting circadian rhythms in melatonin and metabolic outcomes.
- Trial name
- LipidPRC (NCT05276739)
- Testing
- Bright Light, Time-restricted eating, Dim light
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity
Circadian Misalignment and Energy Balance
Preliminary findings from the investigators' lab suggest that circadian misalignment, occurring when meals and sleep are mistimed from one another, alters resting state neuronal processing in areas relevant to food reward and…
- Trial name
- CM (NCT03663530)
- Testing
- Meal times
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type 2 Diabetes
Meal Timing on Postprandial Glucose, Insulin and GLP-1 in Type 2 Diabetes
Enhanced insulin and GLP-1 postprandial response after morning meal versus evening meal, might be underlying explanation of the beneficial effect of eating breakfast with reduced dinner vs skipping breakfast on glycemic control…
- Trial name
- GLP-1inT2D (NCT01977833)
- Testing
- High Calorie Breakfast (BTdiet), High Caloric Dinner (DTdiet)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel Aviv University
Postprandial Hyperglycemia, Insulin Resistance
Night Time Walking to Improve Glycaemic Control in Healthy Adults
Randomised crossover trial to compare early vs late walking on postprandial glycaemic response at night time.
- Trial name
- NCT04958317
- Testing
- Early exercise, Late exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Monash University
Diabetes Mellitus, Type 2, Hyperglycemia, Postprandial
Exercise-meal Timing and Postprandial Glucose Control
Physical activity helps maintain optimal postprandial blood glucose control. However, there is a lack of clear information regarding the optimal meal-activity timing required to maximize blood glucose control.
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia, Postprandial, Physical Activity, Glucose Intolerance
- Trial name
- NCT03730727
- Testing
- Physical activity, Meal
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity
A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants
This is a randomized, open-label, multiple-dose study to evaluate the effects of different volumes of administration water, post-dose fasting duration, and high-fat diet on the pharmacokinetics of the 15 mg dose of MWN109 tablets…
- Trial name
- NCT07801326
- Testing
- MWN109 Tablets
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Meal Timing, Postprandial Glucose
Effect of Circadian Timing of a Standardized Meal on Postprandial Glucose Response in Healthy Adults
This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults.
- Conditions
- Meal Timing, Postprandial Glucose, Glycemic Response to Feeding in Healthy Participants
- Trial name
- NCT07545330
- Testing
- Standardized Test Meal
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Faisal University
Non-Diabetic Disorder of Endocrine Pancreas
Glucose Tolerance, Meal Timing and MTNR1B
The purpose of this investigation is to assess in a community-based cohort of late-night eaters the effect of coincident food intake and endogenous melatonin on glycemic control, and the putative interaction effect of melatonin…
- Trial name
- ONTIME-DINE (NCT03003936)
- Testing
- Dinner timing
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Overweight, Obesity
Timing of Meals for Weight Loss
While eating the majority of energy earlier in the day appears to have a positive effect on weight and cardiometabolic outcomes, it is not clear how eating earlier in the day influences other behaviors that have a circadian…
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- TIME (NCT02204735)
- Testing
- Eat majority of calories in the morning, Eat the majority of calories in the evening
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Type 1 Diabetes Mellitus
Best Timing of Insulin Bolus Before Meals of Different Contents
Post-meal glucose excursions may contribute to the development of diabetes-related complications. These glucose excursions are affected by the food content of the meal and the timing of insulin injection (or insulin pump-bolus)…
- Trial name
- NCT01406496
- Testing
- insulin
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Dietary Modification
Optimizing Meal and Snack Timing to Promote Health
This study will be conducted using standardized techniques to collect blood samples via an acute, randomized, cross-over design.
- Trial name
- S43 (NCT02506218)
- Testing
- 10 + 20 g protein consumption, 30 g protein breakfast, 10 g protein breakfast
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Purdue University
Postprandial Hyperglycemia
Is Mid-morning Breakfast as Healthy as Early-morning Breakfast for Blood Sugar Control in Adolescent Girls?
Repeated, elevated levels of glucose (sugar) within the blood after eating can lead to type 2 diabetes. In adults, eating breakfast lowers blood glucose responses to subsequent meals when compared with skipping breakfast.
- Trial name
- NCT05000944
- Testing
- breakfast omission (BO), early-morning breakfast consumption (EM-BC), mid-morning breakfast consumption (MM-BC)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Type 1 Diabetes (T1D)
The Steno Opti-Bolus-Timing Studies
The project investigates the significance of the timing of insulin dosing for breakfast and lunch with an automated insulin pump and whether it matters if the meal primarily contains high or low glycemic index carbohydrates.
- Trial name
- OBT Studies (NCT07021690)
- Testing
- High glyceamic index meal, Low glyceamic index meal
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Steno Diabetes Center Copenhagen