Blood PressureNCT07578285
A Study Of Starting Strength Barbell Training
A study testing Progressive Barbell Strength Training in people with Blood Pressure and Lipid Profile, run by Mayo Clinic at 1 site in United States.
Trial summary
The purpose of this study is to determine the effect of a 12-week coached Starting Strength barbell training program on systolic and diastolic blood pressure. Read more about this study
- Who is it for?
- Ages 15 to 100 yearsHealthy volunteers can take part
- Conditions the study is for
- Blood Pressure, Lipid Profile, Fasting Glucose
- What is being tested?
- Progressive Barbell Strength Training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Jul 2027to 1 Jan 2029
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 100 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Adults aged 18-100 years
- Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week)
- No participation in structured resistance training programs within the past 6 months.
- Able to safely participate in resistance training as determined by medical screening
- Willing to commit to 3 training sessions per week for 12 weeks
- Able to provide informed consent
- Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company.
Who cannot join
- Current participation in structured resistance training programs
- Cardiovascular disease requiring activity restriction
- Uncontrolled hypertension (systolic BP >180 mm Hg or diastolic BP >110 mm Hg)
- Musculoskeletal conditions precluding safe barbell training
- Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment
- Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects Of Progressive Barbell Strength Training On Cardiovascular And Metabolic Health Markers
The purpose of this study is to determine the effect of a 12-week coached Starting Strength barbell training program on systolic and diastolic blood pressure.
- Conditions
- Blood Pressure, Lipid Profile, Fasting Glucose
- Being tested
- Progressive Barbell Strength Training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Progressive Barbell Strength TrainingOther
Subjects will participate in a 12-week barbell training program, 3 days per week for approximately 60 minutes each session. Training sessions will be conducted by Starting Strength certified coaches at Starting Strength Scottsdale gym.
Core barbell movements including but not limited to: squat, deadlift, bench press, overhead press, and power clean.
| Study group | Role | What they receive |
|---|---|---|
| Starting Strength barbell training program | Experimental | 12-week coached, progressive overload barbell strength training program (Starting Strength) Receives: Other: Progressive Barbell Strength Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in systolic blood pressure
Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)
Measured: Baseline, 16 weeks
Change in diastolic blood pressure
Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)
Measured: Baseline, 16 weeks
Secondary outcomes (5)
Change in total cholesterol
Total cholesterol is the sum of a person's HDL cholesterol, LDL cholesterol, and 20% of their triglyceride levels. Healthy total cholesterol is less than 200 mg/dL of blood
Measured: Baseline, 16 weeks
Change in low-density lipoprotein cholesterol (LDL-C)
Low-density lipoprotein cholesterol (HDL-C) is measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 100 mg/DL and below are considered healthier.
Measured: Baseline, 16 weeks
Change in high-density lipoprotein cholesterol (HDL-C)
High-density lipoprotein cholesterol (HDL-C) is measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 60 mg/DL and above are considered healthier.
Measured: Baseline, 16 weeks
Change in triglycerides
Triglycerides are measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 150 mg/DL and below are considered normal levels.
Measured: Baseline, 16 weeks
Change in fasting glucose
Blood sample taken after an overnight fast. Reported in millimoles per liter (mmol/l)
Measured: Baseline, 16 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start1 Jul 2027 (estimated)
- Primary completion1 Jan 2028 (estimated)
- Study completion1 Jan 2029 (estimated)
Why it stopped: Funding
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Blood PressureStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Joshua Lee, Mayo Clinic
- Investigators
- Joshua Lee, PA-C,MPAS, Principal investigator, Mayo Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07578285
- Sponsor's protocol ID
- 26-001184
- Status last verified
- Jul 2026
- First submitted
- 5 May 2026
- Last updated
- 14 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects Of Progressive Barbell Strength Training On Cardiovascular And Metabolic Health Markers
- ClinicalTrials.gov ID
- NCT07578285
- Acronym / sponsor ID
- 26-001184
- Conditions
- Blood Pressure, Lipid Profile, Fasting Glucose
- Study type
- Interventional
- Recruitment status
- SuspendedReason stopped: Funding
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Study start
- 1 Jul 2027 (estimated)
- Primary completion
- 1 Jan 2028 (estimated)
- Study completion
- 1 Jan 2029 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine the effect of a 12-week coached Starting Strength barbell training program on systolic and diastolic blood pressure.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Starting Strength barbell training program | Experimental | Other: Progressive Barbell Strength Training12-week coached, progressive overload barbell strength training program (Starting Strength) |
Who may qualify
- Ages
- 15 to 100 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (7 listed)
- Adults aged 18-100 years
- Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week)
- No participation in structured resistance training programs within the past 6 months.
- Able to safely participate in resistance training as determined by medical screening
- Willing to commit to 3 training sessions per week for 12 weeks
Key exclusion criteria (6 listed)
- Current participation in structured resistance training programs
- Cardiovascular disease requiring activity restriction
- Uncontrolled hypertension (systolic BP >180 mm Hg or diastolic BP >110 mm Hg)
- Musculoskeletal conditions precluding safe barbell training
- Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Progressive Barbell Strength TrainingSubjects will participate in a 12-week barbell training program, 3 days per week for approximately 60 minutes each session. Training sessions will be conducted by Starting Strength certified coaches at Starting Strength Scottsdale gym. Core barbell movements including but not limited to: squat, deadlift, bench press, overhead press, and power clean. | Other | Starting Strength barbell training program |
Primary outcome
Change in systolic blood pressure
Time frame: Baseline, 16 weeks
Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)
Change in diastolic blood pressure
Time frame: Baseline, 16 weeks
Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)
5 secondary outcomes
Change in total cholesterol
Time frame: Baseline, 16 weeks
Change in low-density lipoprotein cholesterol (LDL-C)
Time frame: Baseline, 16 weeks
Change in high-density lipoprotein cholesterol (HDL-C)
Time frame: Baseline, 16 weeks
Change in triglycerides
Time frame: Baseline, 16 weeks
Change in fasting glucose
Time frame: Baseline, 16 weeks
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jul 2026.
- Mayo Clinic Clinical TrialsLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Joshua Lee, PA-C,MPAS principal investigator
Mayo Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Progressive Barbell Strength Training in people with Blood Pressure and Lipid Profile, run by Mayo Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: paused, as of the sponsor's last update on 14 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in systolic blood pressure (time frame: Baseline, 16 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jul 2026.