Clinical trials: Fasting Glucose
Prediabetes
Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans
This nested pilot Randomized Clinical Trial will determine whether the Diabetes Prevention Program (DPP) enhanced with evidence-based sleep health and time restricted eating interventions ("DPP++") is more effective than the DPP…
- Trial name
- NCT07450118
- Testing
- National Diabetes Prevention Program (DPP), Sleep Health Digital Application, Time-Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Delaware
Impaired Fasting Glucose, Pre Diabetes
Dietary Interventions in Prediabetes
Assessment of glucose metabolism and liver fat after 12 week dietary intervention in pre diabetes subjects. Subjects will be randomized to either high fat (olive oil supplemented),high carb/high fiber (beans supplemented) and…
- Conditions
- Impaired Fasting Glucose, Pre Diabetes, Liver Fat
- Trial name
- NCT01729078
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mayo Clinic
Non-Insulin-dependent Diabetes Mellitus
Study of Metamucil on Blood Glucose and HbA1c in Type II NIDDM Subjects
A double-blind, randomized, placebo-controlled, multi-dose clinical study consisting of 2 phases; 1) an 8-week lead-in period during which patients followed a diet judged to be within the acceptable guidelines of the ADA, and 2)…
- Trial name
- NCT01582282
- Testing
- 3.4 g psyllium BID, 6.8g psyllium BID
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Procter and Gamble
Type II Diabetes Mellitus
Evaluation of Innovated Screening Tools for Type 2 Diabetes Among Chinese Population(SENSIBLE STUDY I)
Evaluation of using 2h-UG combined with FPG, AGEsP alone or in combination with FPG in diabetes screening in Chinese natural population
- Trial name
- NCT03025919
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Prostate Cancer, Metabolic Syndrome
Fasting Mimicking Diet in Prostate Cancer and Metabolic Syndrome
This is a prospective observational cohort study of patients with prostate cancer who have a metabolic syndrome. The study aims to evaluate the role of intermittent fasting (fasting mimicking diet) in these patients.
- Conditions
- Prostate Cancer, Metabolic Syndrome, Intermittent Fasting
- Trial name
- NCT04292041
- Testing
- Fasting mimicking diet
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Galway Clinic
Diabetes Mellitus, Hypertension
An International Prospective, Observational, Multi-centre Study on the Duration of Pre-operative Liquid Fasting
The investigators will be performing an international prospective, observational, multi-centre, cross-sectional study to determine the actual duration of preoperative liquid fasting time in European patients.
- Conditions
- Diabetes Mellitus, Hypertension, Ischaemic Heart Disease, Comorbidities and Coexisting Conditions
- Trial name
- THIRST (NCT06527703)
- Testing
- no intervention
- Where
- Malta
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Mater Dei Hospital, Malta
Impaired Glucose Tolerance, Insulin Sensitivity
Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose
This study will test the effect of four common oral anti-diabetic agents on hepatic insulin sensitivity in South Asian women with impaired glucose tolerance or impaired fasting glucose.
- Conditions
- Impaired Glucose Tolerance, Insulin Sensitivity, Glucose Metabolism Disorders
- Trial name
- DIASA3 (NCT04662866)
- Testing
- Metformin capsule 500 mg, Empagliflozin encapsulated tablet 10 mg, Pioglitazone encapsulated tablet 30 mg, Linagliptin encapsulated tablet 5 mg
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Diabetes Mellitus
Abnormal Glucose Tolerance in Allogeneic Hematopoietic Stem Cell Transplantation
To investigate the impact of abnormal glucose tolerance in hematopoietic stem cell transplantation donors on patients' post-transplant survival outcomes.
- Conditions
- ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Diabetes Mellitus, Impaired Fasting Glucose
- Trial name
- NCT06704542
- Where
- 6 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Ruijin Hospital
Diabetes Mellitus, Type 2
Efficacy and Safety of Vildagliptin as add-on Therapy to Metformin in Patients With Type 2 Diabetes
The purpose of the study is to evaluate the efficacy and safety of vildagliptin 50 mg bid as an add-on therapy to metformin in Japanese patients with T2DM.
- Trial name
- NCT01497522
- Testing
- Vildagliptin
- Where
- 20 sites in Japan
- Volunteers
- 183 people
- Sponsor
- Novartis Pharmaceuticals
Type 1 Diabetes, Obesity
Intermittent Fasting in Adults With Type 1 Diabetes
The majority of adults with type 1 diabetes (T1DM) have either overweight or obesity. As such, dietary management has been recommended as an adjunct to insulin treatment to improve glycemic control and facilitate weight loss in…
- Trial name
- NCT06134986
- Testing
- Time restricted eating, Daily calorie restriction
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Illinois Chicago
Pre-Diabetes, Major Lung or Abdominal Surgery
Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism
Major surgery results in a stress- induced catabolic response, marked by post-operative insulin resistance, hyperglycemia and loss of body protein, which is associated with increased morbidity, mortality and adverse outcomes.
- Conditions
- Pre-Diabetes, Major Lung or Abdominal Surgery, Insulin Resistance
- Trial name
- NCT02393573
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Diabetes Mellitus, Type 2, Obesity
Time-restricted Eating, Window Timing, Type 2 Diabetes Status and Sex on Glycemic Control
This study will evaluate the effectiveness of time-restricted eating (TRE), which is a form of intermittent fasting. When performing TRE, individuals consume all of their calories within a specific time window and then only…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Prediabetic State, Hyperglycemia
- Trial name
- NCT06118931
- Testing
- Early (7:00 - 16:00) TRE, Mid (9:30 - 18:30) TRE, Late (12:00 - 21:00) TRE
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- University of Toronto
Type 2 Diabetes
Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-383 0.5/10/1000mg in Healthy Volunteers
This study is a randomized, open-label, single dose, crossover study to evaluate the pharmacokinetics and safety of CKD-383 in healthy volunteers.
- Trial name
- NCT07304700
- Testing
- CKD-383 0.5/10/1000mg, CKD-501, D744, D150
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Type 2 Diabetes Mellitus
Effects of ISIS 113715 on Insulin Sensitivity, Glucose, and Lipid Metabolism and Energy Expenditure in Type 2 Diabetics
The aim of this study is to examine the effects of ISIS 113715 monotherapy on insulin sensitivity, glucose and lipid metabolism and energy expenditure in subjects with type 2 diabetes mellitus.
- Trial name
- NCT00330200
- Testing
- ISIS 113715
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Diabetes Mellitus, Type 2
Efficacy and Safety of Treatment With Balaglitazone in Type 2 Diabetes Patients on Stable Insulin Therapy
Type 2 diabetes mellitus is a metabolic disorder that is primarily characterized by insulin resistance, relative insulin deficiency, and hyperglycemia.
- Trial name
- BALLET (NCT00515632)
- Testing
- Balaglitazone
- Where
- Denmark
- Volunteers
- 409 people
- Sponsor
- Rheoscience A/S
Pre-diabetes, Type 2 Diabetes
Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass
This study evaluates exenatide, sitagliptin, and glimepiride for the treatment of high blood sugar in patients with impaired fasting glucose or early type 2 diabetes.
- Trial name
- NCT00775684
- Testing
- Exenatide, Sitagliptin, Glimepiride
- Where
- 3 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Non-Insulin-Dependent
Making Ramadhan Fasting a Safer Experience With Technology Study
Type 2 diabetes mellitus (T2DM) is a chronic condition that is one of the major causes of illness, disability, and death in Malaysia with an increasing prevalence.
- Trial name
- NCT02189135
- Testing
- Telemedicine
- Where
- Malaysia
- Volunteers
- 85 people
- Sponsor
- Monash University
PreDiabetes
2-A-Day Study: Twice a Day Meals Study.
Caloric restriction increases lifespan and/or healthspan across multiple species. However implementation of long-term CR in humans is problematic and unacceptable to many individuals.
- Trial name
- NCT03809299
- Testing
- Ad libitum meal timing, Twice a day meals
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Diabetes Mellitus, Pre Diabetes
Glucose Tolerance and Prevention of Diabetes Mellitus Type 2 by Polyherbal Formulation
Primary protocol to this study is to develop a natural remedy to prevent diabetes mellitus in pre-diabetic state and elaborate the effectiveness of polyherbal formulation for carrying out Phase-II, III and IV.
- Trial name
- Phase-1 (NCT03884920)
- Testing
- Polyherbal formulation
- Where
- 2 sites in Pakistan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Laparoscopic Abdominal Surgery
Pre-operative Carbohydrate Drink to Preserve Peri-operative Insulin Sensitivity
Enhanced Recovery after Surgery (ERAS) pathways include multiple evidence-based interventions delivered throughout the peri-operative period that aim to attenuate the surgical stress response and support rapid physiologic and…
- Trial name
- NCT02673502
- Testing
- simple carbohydrate drink, complex carbohydrate drink
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre