Endotracheal IntubationNCT07669259
Bedside Ultrasound for Confirmation of Endotracheal Tube Placement in the Emergency Department
An observational study of Endotracheal Intubation and Endotracheal Tube Placement, run by Antalya Health Sciences University at 1 site in Turkey (Türkiye).
Trial summary
This prospective observational study evaluated the role of bedside ultrasound in confirming endotracheal tube placement in adult patients who underwent endotracheal intubation in the emergency department. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Endotracheal Intubation, Endotracheal Tube Placement, Airway Management
- How many people
- 70 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 10 Jan 2025to 10 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The study population consisted of adult patients aged 18 years or older who presented to the Emergency Department of Antalya Training and Research Hospital and underwent endotracheal intubation as part of routine emergency care. Patients were included after ethics committee approval if bedside ultrasound and capnometric end-tidal carbon dioxide assessment were performed for confirmation of endotracheal tube placement.
Who may be able to join
- Patients aged 18 years or older
- Patients who underwent endotracheal intubation in the emergency department as part of routine emergency care
- Patients in whom bedside ultrasound and capnometric end-tidal carbon dioxide assessment were performed for confirmation of endotracheal tube placement
Who cannot join
- Patients younger than 18 years of age
- Patients with missing or incomplete study data
- Patients with ultrasound images of insufficient quality for evaluation
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
University of Health Sciences, Antalya Training and Research Hospital
Antalya, konyaaltı, 07100
About this study
Official title: The Role of Bedside Ultrasound in Confirming Endotracheal Tube Placement in Patients Undergoing Endotracheal Intubation in the Emergency Department
This prospective observational study evaluated the role of bedside ultrasound in confirming endotracheal tube placement in adult patients who underwent endotracheal intubation in the emergency department. Correct placement of the endotracheal tube is critical because unrecognized incorrect placement may cause hypoxemia, hypoxic brain injury, or death.
In this study, bedside ultrasound was performed during or immediately after endotracheal intubation without interfering with the intubation procedure. Ultrasound findings were compared with capnographic end-tidal carbon dioxide measurement, which was used as the reference method for confirming tube placement. The main aim was to assess whether bedside ultrasound is a useful and reliable method for confirming endotracheal tube position in emergency department patients.
Read the detailed description
This single-center, prospective observational diagnostic accuracy study was conducted in the Emergency Department of Antalya Training and Research Hospital. Adult patients who underwent endotracheal intubation in the emergency department after ethics committee approval were included.
Endotracheal intubation was performed as part of routine emergency care by the most senior emergency medicine resident or an experienced emergency physician. Bedside ultrasound assessment was performed during or immediately after intubation by trained emergency physicians without interrupting or delaying the intubation procedure. The ultrasound examination was performed from the suprasternal notch region to assess the position of the endotracheal tube.
The physicians who performed bedside ultrasound had at least two years of emergency medicine experience and had completed accredited ultrasound training. Before study data collection, they received additional theoretical and practical training focused on ultrasound confirmation of endotracheal tube placement.
Ultrasound findings were compared with capnometric end-tidal carbon dioxide measurement, which was used as the reference method for confirmation of endotracheal tube placement. Ultrasound images were stored in the hospital computer system and reviewed by two qualified, independent radiology specialists. Images or measurements with insufficient quality were excluded from analysis. Agreement between ultrasound assessments was evaluated statistically.
The study aimed to determine whether bedside ultrasound can be used as a rapid, reliable, and practical method for confirming endotracheal tube placement in emergency department patients.
- Conditions
- Endotracheal Intubation, Endotracheal Tube Placement, Airway Management, Ultrasonographic, Capnography
- Keywords
- Bedside ultrasound, Point-of-care ultrasound, Endotracheal tube placement, Capnography, Endotracheal tube confirmation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patients Undergoing Endotracheal Intubation in the Emergency Department | Adult patients who underwent endotracheal intubation in the emergency department were included in this cohort. Endotracheal intubation was performed as part of routine emergency care. Bedside ultrasound was performed during or immediately after intubation by trained emergency physicians without interrupting the procedure. Ultrasound findings were compared with capnometric end-tidal carbon dioxide measurement, which was used as the reference method for confirming endotracheal tube placement. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Diagnostic Accuracy of Bedside Ultrasound for Confirmation of Endotracheal Tube Placement
The diagnostic accuracy of bedside ultrasound for confirming endotracheal tube placement will be evaluated by comparing ultrasound findings with capnometric end-tidal carbon dioxide measurement, which will be used as the reference method. Diagnostic performance will be assessed using sensitivity, specificity, positive predictive value, negative predictive value, overall accuracy, and agreement with the reference method.
Measured: During or immediately after endotracheal intubation, within a maximum of 20 seconds
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jun 2026
- Study start10 Jan 2025
- Primary completion10 Jun 2026
- Study completion10 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Endotracheal IntubationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Antalya Health Sciences University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- MURAT DUYAN, ASSOCIATE PROFESSOR, Principal investigator, University of Health Sciences, Antalya Training and Research HospitalHALIT EKICI, MEDICAL DOCTOR, Study director, University of Health Sciences, Antalya Training and Research HospitalCEMIL KAVALCI, PROFESSOR, Study director, University of Health Sciences, Antalya Training and Research HospitalENGIN DENIZ ARSLAN, ASSOCIATE PROFESSOR, Study director, University of Health Sciences, Antalya Training and Research HospitalFEVZI YILMAZ, Study director, University of Health Sciences, Antalya Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07669259
- Sponsor's protocol ID
- 2025-019
- Status last verified
- Jun 2026
- First submitted
- 20 Jun 2026
- Last updated
- 25 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared publicly because the study includes clinical data from emergency department patients and there may be confidentiality and institutional restrictions. De-identified aggregate results will be reported in scientific publications.
Publications
Long B, Koyfman A, Gottlieb M. Diagnostic Accuracy of Ultrasound for Confirmation of Endotracheal Tube Placement. Acad Emerg Med. 2019 Sep;26(9):1096-1098. doi: 10.1111/acem.13773. Epub 2019 May 23. No abstract available.
PubMed 31046166
Study at a glance
From the registry record, last updated by the sponsor on 25 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Role of Bedside Ultrasound in Confirming Endotracheal Tube Placement in Patients Undergoing Endotracheal Intubation in the Emergency Department
- ClinicalTrials.gov ID
- NCT07669259
- Acronym / sponsor ID
- 2025-019
- Conditions
- Endotracheal Intubation, Endotracheal Tube Placement, Airway Management, Ultrasonographic, Capnography
- Keywords
- Bedside ultrasound, Point-of-care ultrasound, Endotracheal tube placement, Capnography, Endotracheal tube confirmation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Antalya Health Sciences UniversityUniversity, hospital or other
- Study start
- 10 Jan 2025 (actual)
- Primary completion
- 10 Jun 2026 (actual)
- Study completion
- 10 Jun 2026 (actual)
- First posted
- 25 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective observational study evaluated the role of bedside ultrasound in confirming endotracheal tube placement in adult patients who underwent endotracheal intubation in the emergency department. Correct placement of the endotracheal tube is critical because unrecognized incorrect placement may cause hypoxemia, hypoxic brain injury, or death.
In this study, bedside ultrasound was performed during or immediately after endotracheal intubation without interfering with the intubation procedure. Ultrasound findings were compared with capnographic end-tidal carbon dioxide measurement, which was used as the reference method for confirming tube placement. The main aim was to assess whether bedside ultrasound is a useful and reliable method for confirming endotracheal tube position in emergency department patients.
Detailed description
This single-center, prospective observational diagnostic accuracy study was conducted in the Emergency Department of Antalya Training and Research Hospital. Adult patients who underwent endotracheal intubation in the emergency department after ethics committee approval were included.
Endotracheal intubation was performed as part of routine emergency care by the most senior emergency medicine resident or an experienced emergency physician. Bedside ultrasound assessment was performed during or immediately after intubation by trained emergency physicians without interrupting or delaying the intubation procedure. The ultrasound examination was performed from the suprasternal notch region to assess the position of the endotracheal tube.
The physicians who performed bedside ultrasound had at least two years of emergency medicine experience and had completed accredited ultrasound training. Before study data collection, they received additional theoretical and practical training focused on ultrasound confirmation of endotracheal tube placement.
Ultrasound findings were compared with capnometric end-tidal carbon dioxide measurement, which was used as the reference method for confirmation of endotracheal tube placement. Ultrasound images were stored in the hospital computer system and reviewed by two qualified, independent radiology specialists. Images or measurements with insufficient quality were excluded from analysis. Agreement between ultrasound assessments was evaluated statistically.
The study aimed to determine whether bedside ultrasound can be used as a rapid, reliable, and practical method for confirming endotracheal tube placement in emergency department patients.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients Undergoing Endotracheal Intubation in the Emergency Department | – | –Adult patients who underwent endotracheal intubation in the emergency department were included in this cohort. Endotracheal intubation was performed as part of routine emergency care. Bedside ultrasound was performed during or immediately after intubation by trained emergency physicians without interrupting the procedure. Ultrasound findings were compared with capnometric end-tidal carbon dioxide measurement, which was used as the reference method for confirming endotracheal tube placement. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The study population consisted of adult patients aged 18 years or older who presented to the Emergency Department of Antalya Training and Research Hospital and underwent endotracheal intubation as part of routine emergency care. Patients were included after ethics committee approval if bedside ultrasound and capnometric end-tidal carbon dioxide assessment were performed for confirmation of endotracheal tube placement.
Key inclusion criteria (3 listed)
- Patients aged 18 years or older
- Patients who underwent endotracheal intubation in the emergency department as part of routine emergency care
- Patients in whom bedside ultrasound and capnometric end-tidal carbon dioxide assessment were performed for confirmation of endotracheal tube placement
Key exclusion criteria (3 listed)
- Patients younger than 18 years of age
- Patients with missing or incomplete study data
- Patients with ultrasound images of insufficient quality for evaluation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Diagnostic Accuracy of Bedside Ultrasound for Confirmation of Endotracheal Tube Placement
Time frame: During or immediately after endotracheal intubation, within a maximum of 20 seconds
The diagnostic accuracy of bedside ultrasound for confirming endotracheal tube placement will be evaluated by comparing ultrasound findings with capnometric end-tidal carbon dioxide measurement, which will be used as the reference method. Diagnostic performance will be assessed using sensitivity, specificity, positive predictive value, negative predictive value, overall accuracy, and agreement with the reference method.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jun 2026.
- Background: PubMed 31046166Long B, Koyfman A, Gottlieb M. Diagnostic Accuracy of Ultrasound for Confirmation of Endotracheal Tube Placement. Acad Emerg Med. 2019 Sep;26(9):1096-1098. doi: 10.1111/acem.13773. Epub 2019 May 23. No abstract available.
- Individual participant dataSharing planned: No. Individual participant data will not be shared publicly because the study includes clinical data from emergency department patients and there may be confidentiality and institutional restrictions. De-identified aggregate results will be reported in scientific publications.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
MURAT DUYAN, ASSOCIATE PROFESSOR principal investigator
University of Health Sciences, Antalya Training and Research Hospital
HALIT EKICI, MEDICAL DOCTOR study director
University of Health Sciences, Antalya Training and Research Hospital
CEMIL KAVALCI, PROFESSOR study director
University of Health Sciences, Antalya Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Endotracheal Intubation and Endotracheal Tube Placement, run by Antalya Health Sciences University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Diagnostic Accuracy of Bedside Ultrasound for Confirmation of Endotracheal Tube Placement (time frame: During or immediately after endotracheal intubation, within a maximum of 20 seconds). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07669259, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jun 2026.