Altered Passive EruptionNCT07762482
Periodontal Tissue Stability After Surgical Correction of Altered Passive Eruption
A study testing Esthetic Crown-Lengthening Surgery in people with Altered Passive Eruption, run by University of Sao Paulo at 1 site in Brazil.
Trial summary
This prospective, single-group interventional study will evaluate the stability of periodontal tissues after esthetic periodontal surgery for the correction of altered passive eruption in individuals with excessive gingival display. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Altered Passive Eruption
- What is being tested?
- Esthetic Crown-Lengthening Surgery
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteBrazil
- Study dates
- 10 Aug 2026to Feb 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults with an esthetic complaint related to excessive gingival display.
- Diagnosis of altered passive eruption as one of the etiologic factors associated with excessive gingival display.
- Altered passive eruption involving the alveolar bone.
Who cannot join
- Current orthodontic treatment.
- Active periodontal disease.
- Systemic conditions that contraindicate periodontal surgical procedures, including uncontrolled autoimmune diseases.
- Use of medications that may interfere with the inflammatory response or wound healing, including corticosteroids or immunosuppressive agents.
- Current smokers.
- Former smokers who discontinued smoking less than 12 months before enrollment.
- Pregnant or breastfeeding individuals.
- Excessive gingival display primarily associated with lip hypermobility or vertical maxillary excess without concomitant altered passive eruption.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Arthur Belem Novaes Jr, DDS, PhD contact
Brazil1 site, 1 recruiting
- Recruiting
School of Dentistry of Ribeirão Preto, University of Sao Paulo
Ribeirão Preto, São Paulo, 14040-904
Edgar Daniel Vargas Quiroga, DDS, MSc, +5511982499298, edgar.vargasquiroga@usp.br
Arthur Belem Novaes Jr, DDS, PhD, novaesjr@forp.usp.br
About this study
Official title: Analysis of Periodontal Tissue Stability After Surgical Correction of Altered Passive Eruption in Individuals With Excessive Gingival Display
This prospective, single-group interventional study will evaluate the stability of periodontal tissues after esthetic periodontal surgery for the correction of altered passive eruption in individuals with excessive gingival display. Ten adult participants with excessive gingival display associated with altered passive eruption and involvement of the alveolar bone will be included.
Participants will undergo esthetic crown-lengthening surgery consisting of gingivectomy and osseous recontouring. Periodontal clinical measurements, intraoral digital scans, cone-beam computed tomography, standardized photographs, and patient-reported outcomes will be obtained before surgery and during follow-up. Clinical and three-dimensional tissue changes, esthetic perception, satisfaction, and oral health-related quality of life will be evaluated for up to 12 months after treatment.
Read the detailed description
Excessive gingival display may be associated with altered passive eruption, a condition characterized by excessive gingival coverage of the anatomical crown and an altered relationship between the gingival margin, cementoenamel junction, and alveolar bone crest. Esthetic crown-lengthening procedures may be indicated to expose the anatomical crown and establish an appropriate periodontal tissue relationship.
This prospective, non-randomized, before-and-after clinical study will include 10 adult participants presenting with an esthetic complaint related to excessive gingival display and a diagnosis of altered passive eruption involving the alveolar bone.
Before surgery, participants will undergo clinical examination and periodontal preparation. Esthetic periodontal surgery will consist of gingivectomy associated with osseous recontouring. The surgical approach, including flap elevation when required, will be determined according to the periodontal phenotype and local anatomical characteristics.
Periodontal clinical measurements will be performed before surgery and during postoperative follow-up. Intraoral digital scanning will be performed before treatment and at 3, 6, and 12 months to evaluate three-dimensional changes and soft-tissue stability. Cone-beam computed tomography will also be used to evaluate periodontal tissue dimensions and remodeling. Standardized intraoral and extraoral photographs will document esthetic changes.
Patient-reported outcomes, including postoperative discomfort, esthetic perception, satisfaction, and oral health-related quality of life, will also be assessed. Participants will be followed for 12 months after surgery to determine the stability of the clinical and three-dimensional periodontal outcomes.
- Conditions
- Altered Passive Eruption
- Being tested
- Esthetic Crown-Lengthening Surgery
- Keywords
- Gummy Smile, Esthetic Crown Lengthening, Gingivectomy, Osseous Surgery, Periodontal Plastic Surgery, Periodontal Tissue Stability, Intraoral Scanning
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Esthetic Crown-Lengthening SurgeryProcedure or surgery
Esthetic periodontal surgery will be performed to correct altered passive eruption. Gingival tissue will be removed by an internal bevel gingivectomy. Osseous recontouring will then be performed to establish an adequate relationship between the cementoenamel junction and the alveolar bone crest. Depending on the periodontal phenotype and anatomical characteristics, osseous recontouring may be performed with or without flap elevation.
| Study group | Role | What they receive |
|---|---|---|
| Esthetic Crown-Lengthening Surgery | Experimental | Participants with excessive gingival display associated with altered passive eruption and alveolar bone involvement will undergo esthetic crown-lengthening surgery consisting of gingivectomy and osseous recontouring. Flap elevation may be performed when indicated according to the periodontal phenotype and local anatomical characteristics. Receives: Procedure: Esthetic Crown-Lengthening Surgery |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean Change From Baseline in Clinical Crown Length
Clinical crown length will be recorded in millimeters. The mean change from baseline will be calculated at each postoperative assessment to evaluate the stability of the surgical outcome over time.
Measured: Baseline, 2 weeks, 3 months, 6 months, and 12 months after surgery
Secondary outcomes (6)
Mean Change From Baseline in the Distance Between the Cementoenamel Junction and Alveolar Bone Crest
The distance between the cementoenamel junction and the alveolar bone crest will be measured in millimeters using cone-beam computed tomography to evaluate postoperative periodontal tissue remodeling.
Measured: Baseline, 3 months, 6 months, and 12 months after surgery
Mean Change From Baseline in Gingival Thickness
Gingival thickness will be measured in millimeters using cone-beam computed tomography to evaluate changes in periodontal soft-tissue dimensions after surgery.
Measured: Baseline, 3 months, 6 months, and 12 months after surgery
Mean Change From Baseline in Alveolar Bone Thickness
Alveolar bone thickness will be measured in millimeters using cone-beam computed tomography to evaluate bone remodeling after esthetic crown-lengthening surgery.
Measured: Baseline, 3 months, 6 months, and 12 months after surgery
Three-Dimensional Change in Gingival Soft Tissues
Intraoral digital scans obtained at follow-up visits will be compared with baseline digital models to assess three-dimensional changes in gingival morphology and soft-tissue stability.
Measured: Baseline, 3 months, 6 months, and 12 months after surgery
Change in Oral Health-Related Quality of Life Assessed by OHIP-14
Oral health-related quality of life will be assessed using the 14-item Oral Health Impact Profile (OHIP-14). Each item is scored from 0 (never) to 4 (very often), with higher scores indicating a greater negative impact of oral health on quality of life.
Measured: Baseline, 3 months, 6 months, and 12 months after surgery
Postoperative Pain Intensity
Postoperative pain will be assessed using a 0-to-100 numerical rating scale, where 0 indicates no pain and 100 indicates unbearable pain.
Measured: 3 months, 6 months, and 12 months after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Aug 2026
- Study start10 Aug 2026
- Primary completionFeb 2028 (estimated)
- Study completionFeb 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Altered Passive EruptionStudies of the same condition, open and under way.
- More trials run by University of Sao PauloThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- All participants will receive the same esthetic periodontal surgical intervention and will be followed longitudinally for 12 months. Outcomes will be compared with each participant's baseline measurements.
- Masking
- None (open label)
- Enrolment
- 10 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Sao Paulo
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Arthur Belem Novaes Jr, University of Sao Paulo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07762482
- Sponsor's protocol ID
- CAAE: 99545426.9.0000.5419
- Status last verified
- Aug 2026
- First submitted
- 8 Aug 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Analysis of Periodontal Tissue Stability After Surgical Correction of Altered Passive Eruption in Individuals With Excessive Gingival Display
- ClinicalTrials.gov ID
- NCT07762482
- Acronym / sponsor ID
- CAAE: 99545426.9.0000.5419
- Conditions
- Altered Passive Eruption
- Keywords
- Gummy Smile, Esthetic Crown Lengthening, Gingivectomy, Osseous Surgery, Periodontal Plastic Surgery, Periodontal Tissue Stability, Intraoral Scanning
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 10 participants (estimated)
- Lead sponsor
- University of Sao PauloUniversity, hospital or other
- Study start
- 10 Aug 2026 (actual)
- Primary completion
- Feb 2028 (estimated)
- Study completion
- Feb 2028 (estimated)
- First posted
- 13 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective, single-group interventional study will evaluate the stability of periodontal tissues after esthetic periodontal surgery for the correction of altered passive eruption in individuals with excessive gingival display. Ten adult participants with excessive gingival display associated with altered passive eruption and involvement of the alveolar bone will be included.
Participants will undergo esthetic crown-lengthening surgery consisting of gingivectomy and osseous recontouring. Periodontal clinical measurements, intraoral digital scans, cone-beam computed tomography, standardized photographs, and patient-reported outcomes will be obtained before surgery and during follow-up. Clinical and three-dimensional tissue changes, esthetic perception, satisfaction, and oral health-related quality of life will be evaluated for up to 12 months after treatment.
Detailed description
Excessive gingival display may be associated with altered passive eruption, a condition characterized by excessive gingival coverage of the anatomical crown and an altered relationship between the gingival margin, cementoenamel junction, and alveolar bone crest. Esthetic crown-lengthening procedures may be indicated to expose the anatomical crown and establish an appropriate periodontal tissue relationship.
This prospective, non-randomized, before-and-after clinical study will include 10 adult participants presenting with an esthetic complaint related to excessive gingival display and a diagnosis of altered passive eruption involving the alveolar bone.
Before surgery, participants will undergo clinical examination and periodontal preparation. Esthetic periodontal surgery will consist of gingivectomy associated with osseous recontouring. The surgical approach, including flap elevation when required, will be determined according to the periodontal phenotype and local anatomical characteristics.
Periodontal clinical measurements will be performed before surgery and during postoperative follow-up. Intraoral digital scanning will be performed before treatment and at 3, 6, and 12 months to evaluate three-dimensional changes and soft-tissue stability. Cone-beam computed tomography will also be used to evaluate periodontal tissue dimensions and remodeling. Standardized intraoral and extraoral photographs will document esthetic changes.
Patient-reported outcomes, including postoperative discomfort, esthetic perception, satisfaction, and oral health-related quality of life, will also be assessed. Participants will be followed for 12 months after surgery to determine the stability of the clinical and three-dimensional periodontal outcomes.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- All participants will receive the same esthetic periodontal surgical intervention and will be followed longitudinally for 12 months. Outcomes will be compared with each participant's baseline measurements.
| Arm | Type | Receives |
|---|---|---|
| Esthetic Crown-Lengthening Surgery | Experimental | Procedure: Esthetic Crown-Lengthening SurgeryParticipants with excessive gingival display associated with altered passive eruption and alveolar bone involvement will undergo esthetic crown-lengthening surgery consisting of gingivectomy and osseous recontouring. Flap elevation may be performed when indicated according to the periodontal phenotype and local anatomical characteristics. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Adults with an esthetic complaint related to excessive gingival display.
- Diagnosis of altered passive eruption as one of the etiologic factors associated with excessive gingival display.
- Altered passive eruption involving the alveolar bone.
Key exclusion criteria (8 listed)
- Current orthodontic treatment.
- Active periodontal disease.
- Systemic conditions that contraindicate periodontal surgical procedures, including uncontrolled autoimmune diseases.
- Use of medications that may interfere with the inflammatory response or wound healing, including corticosteroids or immunosuppressive agents.
- Current smokers.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Esthetic Crown-Lengthening SurgeryEsthetic periodontal surgery will be performed to correct altered passive eruption. Gingival tissue will be removed by an internal bevel gingivectomy. Osseous recontouring will then be performed to establish an adequate relationship between the cementoenamel junction and the alveolar bone crest. Depending on the periodontal phenotype and anatomical characteristics, osseous recontouring may be performed with or without flap elevation. | Procedure or surgery | Esthetic Crown-Lengthening Surgery |
Primary outcome
Mean Change From Baseline in Clinical Crown Length
Time frame: Baseline, 2 weeks, 3 months, 6 months, and 12 months after surgery
Clinical crown length will be recorded in millimeters. The mean change from baseline will be calculated at each postoperative assessment to evaluate the stability of the surgical outcome over time.
6 secondary outcomes
Mean Change From Baseline in the Distance Between the Cementoenamel Junction and Alveolar Bone Crest
Time frame: Baseline, 3 months, 6 months, and 12 months after surgery
Mean Change From Baseline in Gingival Thickness
Time frame: Baseline, 3 months, 6 months, and 12 months after surgery
Mean Change From Baseline in Alveolar Bone Thickness
Time frame: Baseline, 3 months, 6 months, and 12 months after surgery
Three-Dimensional Change in Gingival Soft Tissues
Time frame: Baseline, 3 months, 6 months, and 12 months after surgery
Change in Oral Health-Related Quality of Life Assessed by OHIP-14
Time frame: Baseline, 3 months, 6 months, and 12 months after surgery
Postoperative Pain Intensity
Time frame: 3 months, 6 months, and 12 months after surgery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
Related trials for Altered Passive Eruption
Not yet recruiting
Accuracy of Stackable Double Periodontal Guide in Esthetic Crown Lengthening
Gummy Smile of Altered Passive Eruption Type 1B
Enrolling by invitation
Laser-Assisted Minimally Invasive Esthetic Crown Lengthening Using Flapless vs. Tunneled Flap Approach
Altered Passive Eruption of Teeth
RecruitingObservational study
Gummy Smile and Altered Passive Eruption Prevalence
Altered Passive Eruption of Teeth
Active, not recruiting
Clinical Evaluation of Gingivalstat Approach Compared to Conventional Esthetic Crown Lengthening on the Stability of The Gingival Margin in Patients With Altered Passive Eruption.
Gummy Smile, Altered Passive Eruption of Teeth
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Arthur Belem Novaes Jr, DDS, PhD contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Esthetic Crown-Lengthening Surgery in people with Altered Passive Eruption, run by University of Sao Paulo at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Edgar Daniel Vargas Quiroga, DDS, MSc (+5511982499298, edgar.vargasquiroga@usp.br), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean Change From Baseline in Clinical Crown Length (time frame: Baseline, 2 weeks, 3 months, 6 months, and 12 months after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.