Clinical trials: Photobiomodulation (PBM)
Oral Mucositis
Prevention of Oral Mucositis Using Photobiomodulation Therapy
Oral mucositis is a significant and common toxicity experienced by patients who receive high-dose chemotherapy as a preparatory regimen for a hematopoietic cell transplant (HCT).
- Trial name
- NCT04227340
- Testing
- Photobiomodulation Therapy (PBM), Pain and Oral Function Assessment, Parent-Reported Satisfaction Survey
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- St. Jude Children's Research Hospital
Low Level Laser Therapy, Photobiomodulation
Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia
The photobiomodulation (PBM) shows positive results in muscle performance, fatigue reduction, management of blood lactate production, analgesia and in the increase of VO2 maximal, favoring the increase of ATP production and thus…
- Conditions
- Low Level Laser Therapy, Photobiomodulation, Performance, Sport
- Trial name
- NCT05595564
- Testing
- Photobiomodulation therapy
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Epilepsy
An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy
Do you have Epilepsy? Would you like to participate in a study using PhotoBioModulation (PBM)? PBM is being researched for potential benefits in resolving many stress-related brain disorders.
- Trial name
- PBM Rise (NCT07509177)
- Testing
- Photobiomodulation
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Cynthia Kerson
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Photobiomodulation on NMES-Induced Muscle Fatigue and Damage
Neuromuscular electrical stimulation (NMES) is effective for strength training and rehabilitation, but non-selective motor unit recruitment often induces rapid fatigue, discomfort, and muscle damage.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS), Muscle Damage, Photobiomodulation (PBM)
- Trial name
- NCT07790016
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
MCI, Amnestic Mild Cognitive Disorder
Neuro RX Gamma for Amnestic Mild Cognitive Impairment (aMCI)
Over 50 million people worldwide are currently living with dementia-a number projected to rise to 152 million by 2050. Mitochondrial dysfunction in the brains of individuals with Mild Cognitive Impairment (MCI) and Alzheimer's…
- Trial name
- NCT05563298
- Testing
- Neuro RX Gamma device
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Orthodontics, Root Resorption
Effects of PBM on Fixed-appliance Orthodontic Patients
The aim of this study is to investigate the effects of photobiomodulation therapy (PBM) on the dental and periodontal health of patients undergoing fixed-appliance orthodontic treatment, including orthodontically induced root…
- Trial name
- NCT06199674
- Testing
- photobiomodulation therapy, orthodontic fixed-appliance
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Post Covid-19 Elderly
Effect of PBM on Functional Capacity and Fatigability in Post Covid-19 Elderly
Participants had randomly divided into two equal groups. Group (A) which is the study group will receive photobiomodulation session two times per week for four weeks.
- Trial name
- NCT05094726
- Testing
- photobiomodulation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Macular Degeneration, Age Related
Evaluating Metabolic Changes Induced by PhotoBioModulation Through Spectrally Resolved Autofluorescence in Dry Age-Related Macular Degeneration Patients
The best treatment to prevent the evolution of early and intermediate forms of dAMD to atrophic degeneration is PhotoBioModulation (PBM).
- Trial name
- PBM-dAMD (NCT06582511)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Francesco Bandello
Alzheimer's Disease
Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study
The purpose of this study is to see if a special light treatment, called photobiomodulation, can help people with memory problems such as Mild Cognitive Impairment or Mild Dementia due to Alzheimer's disease.
- Trial name
- NCT07224607
- Testing
- Photobiomodulation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Cedars-Sinai Medical Center
Graft-Versus-Host Disease, GVHD
A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant
The purpose of this study is to find out whether photobiomodulation/PBM therapy using the Thor LX2.3 therapy system is a safe and effective treatment for oral Graft-Versus-Host Disease/GVHD.
- Conditions
- Graft-Versus-Host Disease, GVHD, Undefined
- Trial name
- NCT05675930
- Testing
- Photobiomodulation Therapy
- Where
- 9 sites in United States
- Volunteers
- 44 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis
There is no cure or approved treatments for ME. Several causes have been implicated in ME, including poor mitochondrial function. Mitochondria are the powerhouse of cells, producing energy.
- Trial name
- LightMEup (NCT06145867)
- Testing
- Photobiomodulation therapy
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Quadram Institute Bioscience
Urological Surgery, Photobiomodulation (PBM)
PBM Patch for Postoperative Pain Relief After Urological Surgery
This study is a prospective, randomized, double-blind, placebo-controlled clinical study designed to evaluate the efficacy and safety of a photobiomodulation (PBM) patch (Super Vi PBM Patch - Soothing) and an enhanced PBM patch…
- Conditions
- Urological Surgery, Photobiomodulation (PBM), Non-pharmacological Intervention, Double-blind Randomized Controlled Study
- Trial name
- NCT07671612
- Testing
- Super Vi PBM Patch - Soothing, Super Vi PBM Patch - Soothing EX
- Where
- 2 sites in Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Anterior Knee Pain, Photobiomodulation (PBM)
Photobiomodultion in Anterior Knee Pain
The goal of this clinical trial is to assess the augmented recovery in the adolescent females with patellar tendinopathy using Phot- Biomodulation
- Conditions
- Anterior Knee Pain, Photobiomodulation (PBM), Laser Therapy
- Trial name
- PBM (NCT07865325)
- Testing
- Photobiomodultion with Laser scanning, patellar mobilization with exercise therapy
- Where
- Jordan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- New Ismailia National University
AMCI - Amnestic Mild Cognitive Impairment
Effects of Photobiomodularion on Brain Connectivity and Cognitive Function in Cognitive Impairment
The goal of this clinical trial is to learn if transcranial photobiomodulation (t-PBM), a light-based brain therapy, can help improve memory and cognitive skills in older adults with amnestic mild cognitive impairment (aMCI).
- Trial name
- PBM-CogConnect (NCT07287527)
- Testing
- Active transcranial Photobiomodulation, Cognitive Rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uskudar University
Dry Age-related Macular Degeneration
A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (GLOBALIGHT)
The purpose of this registry study is to collect real life data pertaining to the safety and clinical effectiveness of multi-wavelength photobiomodulation (PBM) as provided by the Valeda Light Delivery System in participants with…
- Trial name
- NCT06351605
- Testing
- Valeda® Light Delivery System
- Where
- 6 sites in United States, Norway
- Volunteers
- 500 people
- Sponsor
- LumiThera, Inc.
Post-stroke Aphasia
The Effect of PBM on the Electrical Activity of the Brain in Stroke Patients
The Effect of Low-Level Light Therapy on the Electrical Activity of the Brain in Stroke Patients
- Trial name
- PBM (NCT07323823)
- Testing
- photobiomodulation (PBM), control group-receive speech therapy
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Diabetic Foot Ulcer
High Intensity LED Photobiomodulation Therapy for Chronic Leg and Foot Ulcers
Diabetic and venous ulcers affect many people, and severe cases can end up in amputation and even death because of infection. In 2011, the total cost for care of diabetic foot ulcers alone, to the Canadian health care system, was…
- Trial name
- NCT04300205
- Testing
- High intensity LED light device
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Illumacell Inc.
Healing Surgical Wounds, Pain
L-PRF vs PBM on Extraction Socket Healing
The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and…
- Trial name
- NCT06328413
- Testing
- photobiomodulation, Leukocyte and Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Photobiomodulation, Dementia With Lewy Bodies
Evaluating How Red-light Therapy Applied to the Head Affects Symptoms, Daily Life, and Brain Activity in People With Dementia With Lewy Bodies
Dementia with Lewy bodies (DLB) is a neurodegenerative disease diagnosed primarily based on the presence of cognitive decline, which may include difficulties with memory, attention, and more.
- Trial name
- LewyLIGHT (NCT07602296)
- Testing
- LUCIOLE CAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
CREST Syndrome, Calcinosis Cutis
Localized Effects of PBM and Exogenous NO on CREST Patients Calcinosis Cutis & Raynaud Phenomenon
Background CREST is an acronym for the cardinal clinical features of the syndrome (Calcinosis, Raynaud phenomenon, Esophageal dysmotility, Sclerodactyly, and Telangiectasia) and part of the heterogeneous group of sclerodermas.
- Conditions
- CREST Syndrome, Calcinosis Cutis, Raynaud Phenomenon
- Trial name
- NCT03972566
- Testing
- INOMAX
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- RoseLab Skin Optics Laboratory