Clinical trials: Adolescence
Autism Spectrum Disorder, Earthquake
The Effect of Parent Mediated Intervention Program on Children With ASD Exposed to Earthquake in Turkey in February 2023
After devastating natural events such as earthquakes, individuals with special needs experience much more difficulties. There is a limited number of studies investigating the impact of disasters on individuals with autism.
- Conditions
- Autism Spectrum Disorder, Earthquake, Behavior Problem of Childhood and Adolescence
- Trial name
- NCT05998382
- Testing
- Online group-based parent-mediated intervention program
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sabri Hergüner
Aggression, Adolescence
Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals
This study evaluates the effectiveness of a wise Intervention to reduce aggressive behaviors and promote prosocial behaviors toward LGB-TNB individuals among Spanish adolescents.
- Trial name
- LGB-TNB (NCT07212283)
- Testing
- Wise Intervention LGB-TNB, Values alignment wise intervention
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Pregnancy in Adolescence, Adolescent Health
An Evaluation of the Yes You Can... Make Smart Choices Curriculum
The New Jersey Physicians Advisory Group (NJPAG) previously created the Yes You Can…Make Smart Choices! (YYC…MSC!) program with the goal of preventing teen pregnancy and enhancing character development in youth.
- Trial name
- NCT05320666
- Testing
- Yes You Can…Make Smart Choices! (YYC…MSC!) program
- Where
- 13 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- New Jersey Physicians Advisory Group
Depressive Disorder, Depression
Evaluation of the Naturalistic User Experience of the Website "Ich Bin Alles"
Using a multi-method approach, the aim of this study is to investigate the naturalistic user experience and acceptance of the German website "ich bin alles".
- Conditions
- Depressive Disorder, Depression, Depression in Children, Depression in Adolescence
- Trial name
- NCT06668701
- Testing
- "ich bin alles"
- Where
- Germany
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Tourette Syndrome in Adolescence
Cognitive and Brain Development in Adolescents With Gilles de la Tourette Syndrome
In children with neurodevelopmental disorders, adolescence is usually associated with a reshaping of the clinical picture and symptomatology.
- Trial name
- CADETS (NCT04179435)
- Testing
- Behavioral testing on cognitive computerized tasks, brain MRI, TMS
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Social Withdrawal of Childhood or Adolescence, Preterm Infant
The Effect of a Neonatologist's Standardized Guidance Intervention on Preterm Infants With Relational Withdrawal.
The objective of this project is to determine the effect of the verbal intervention on the decrease in sustained social withdrawal in late and moderately late preterm infants.
- Trial name
- NCT03212547
- Testing
- Verbal Intervention
- Where
- 2 sites in Chile
- Volunteers
- 110 people
- Sponsor
- Clinica Alemana de Santiago
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder
Empowering Perinatal Adolescents Through Writing
This is a feasibility and acceptability study of Written Exposure Therapy (WET) for PTSD in pregnant and postpartum adolescents and youth with PTSD.
- Conditions
- Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
- Trial name
- EMPWR (NCT06771817)
- Testing
- Written Exposure Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Texas Southwestern Medical Center
Type 1 Diabetes Mellitus, T1D
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103.
- Conditions
- Type 1 Diabetes Mellitus, T1D, T1DM, T1DM - Type 1 Diabetes Mellitus
- Trial name
- NCT06783309
- Testing
- CNP-103
- Where
- 45 sites in United States
- Volunteers
- 72 people
- Sponsor
- COUR Pharmaceutical Development Company, Inc.
Opioid Use Disorder, Dual Diagnosis
Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness
Homelessness severely affects health and well-being and is particularly negative for youth. Between 70-95% of youth experiencing homelessness (YEH) report problem substance use and 66-89% have a mental health disorder.
- Conditions
- Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence
- Trial name
- NCT06311838
- Testing
- Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Violence in Adolescence, Racism
Forging Hopeful Futures to Reduce Youth Violence
This cluster-randomized community-partnered study will examine the effectiveness of a racial-, gender-, and economic-justice focused youth violence prevention program called Forging Hopeful Futures with youth ages 13-19.
- Conditions
- Violence in Adolescence, Racism, Adolescent Behavior, Coping Skills
- Trial name
- FHF (NCT05743478)
- Testing
- Forging Hopeful Futures, Wellness Check-ins
- Where
- 2 sites in United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression in Adolescence, Obesity & Overweight
Digitally Enhanced Cognitive-Behavioral Therapy
Adolescent depression is a major public health problem. Depression affects adolescents' emotional well-being now and in the future, and it also affects their physical health, especially the risk for heart disease and other…
- Conditions
- Depression in Adolescence, Obesity & Overweight, Cognitive-behavioral Therapy, Mobile Health Technology (mHealth)
- Trial name
- CBT+ (NCT07569991)
- Testing
- Cognitive-behavioral therapy (CBT), Digital app
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Colorado State University
Depression in Adolescence, Depression in Adults
Neuro-affective Response to Light in Depressed Adolescents and Young Adults
The goal of this neuroimaging pilot study is to understand developmental differences in the impact of therapeutic wavelength light (blue light) versus a non-therapeutic wavelength (red light) on emotional brain function in…
- Trial name
- NCT05712772
- Testing
- Blue Light, Red Light
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Alcohol Drinking, Violence in Adolescence
The Healthy Families Bright Futures Program
The goal of this clinical trial is to learn about an online group program (Healthy Families Bright Futures program) for LGBTQ+ teens and their caregivers.
- Trial name
- NCT06309134
- Testing
- Healthy Families Bright Futures Program
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Parenting, Adolescent - Emotional Problem
Optimizing Residential Treatment Gains for Adolescents
The goal of this randomized controlled trial is to determine the feasibility, acceptability, and preliminary effects of a web-based parent training augmented with facilitated parent groups.
- Conditions
- Parenting, Adolescent - Emotional Problem, Mental Disorder in Adolescence
- Trial name
- NCT05764369
- Testing
- Parenting Wisely Residential Treatment (PWRT), TAU
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Ohio State University
Cancer in Adolescence
Needs Navigation for Caregivers of AYAs
The overall aim of the study is to address unmet health-related social needs and reduce outcome disparities among AYA (adolescent and young adult) cancer survivors.
- Trial name
- Cope-CAYAC (NCT06296641)
- Testing
- Needs navigation intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Columbia University
Eating Disorders in Adolescence, Body Dissatisfaction
Young Athlete Body Project - Prevention of Body Dissatisfaction and Eating Disorders Among Adolescent Athletes
Body dissatisfaction is common among adolescents and is a well-established risk factor for the development of eating disorders. Young athletes may be particularly vulnerable because they are exposed to appearance-related…
- Conditions
- Eating Disorders in Adolescence, Body Dissatisfaction, Mental Health
- Trial name
- YABP (NCT07795333)
- Testing
- Young Athlete Body Project
- Where
- 2 sites in Norway
- Volunteers
- 1,740 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Surgery, Rehabilitation
Postoperative Rehabilitation in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity occurring in growing individuals. In cases with progressive curvature, posterior spinal fusion and instrumentation (PSF) is considered the…
- Conditions
- Surgery, Rehabilitation, Scoliosis; Adolescence
- Trial name
- NCT07791485
- Testing
- Exercise-Based Rehabilitation Program
- Volunteers
- 42 people
- Sponsor
- Marmara University