Clinical trials: Adolescent Depression
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder
VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression
Major depressive disorder (MDD) is a prevalent and disabling mental health condition. A recent meta-analysis shows that across all forms of psychotherapy, only 43% of all depressive patients fully recover from MDD and relapse…
- Trial name
- VR-Moodboost (NCT05486676)
- Testing
- VR-Moodboost; a Virtual Reality intervention for depression to enhance positive affect and reduce depressive symptoms.
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Claudi Bockting
Depressive Disorder
Prevention of Adolescent Major Depression
The main purpose of this study is to assess the effect of a cognitive group intervention on prevention of major depression in 14-15-year-old adolescents.
- Trial name
- CWSA-Fin (NCT00611052)
- Testing
- the Adolescent Coping with Stress, Treatment as usual, usual health education
- Where
- 3 sites in Finland
- Volunteers
- 65 people
- Sponsor
- Finnish Institute for Health and Welfare
Suicidal Ideation, Suicide Attempt
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts.
- Conditions
- Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder
- Trial name
- NCT07628192
- Testing
- CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The Cleveland Clinic
Tourette Syndrome in Adolescence, Social Adjustment
Board Game Project for Adolescents with Tourette Syndrome
The study aims to investigate the effectiveness of using a board game to improve adolescents' tics, mental health, and interpersonal interactions.
- Conditions
- Tourette Syndrome in Adolescence, Social Adjustment, Psychosocial Functioning
- Trial name
- NCT05566236
- Testing
- board game
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Anxiety, Depression
Attention Bias Modification Training for Young People
Attention bias modification training (ABMT) is a computer-based attention training programme designed to modify the way a person's attention is directed to mild threats in the environment.
- Trial name
- NCT02270671
- Testing
- ABMT
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Depression
Strong Connections
The purpose of this study is to compare two talking forms of therapy designed to help reduce depressive symptoms in teenagers: Interpersonal Psychotherapy for Adolescents and Treatment as Usual.
- Trial name
- NCT03308864
- Testing
- Interpersonal Psychotherapy for Adolescents, Treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Adolescent Behavior
Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk…
- Trial name
- ASAP (NCT02272179)
- Testing
- As Safe As Possible, Brite, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Bipolar Disorder, Major Depressive Disorder
Early Intervention for Youth at Risk for Bipolar Disorder
Children or teens with mood swings or depression who have a parent with bipolar disorder are at high risk for developing bipolar disorder themselves.
- Trial name
- NCT01483391
- Testing
- Enhanced Care, Family-Focused Treatment
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Emotion Regulation, Depression
JoyPop Mobile Mental Health App With Indigenous Youth
Indigenous youth in Northwestern Ontario who need mental health supports experience longer waits than non-Indigenous youth within the region and when compared to youth in other more urban areas.
- Conditions
- Emotion Regulation, Depression, Anxiety, Stress
- Trial name
- NCT05898516
- Testing
- Usual Practice + JoyPop
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Suicide, Depression
Adaptation of a French E-health Tool for Suicide Prevention in Young Populations
"France's suicide rate is among the highest in Europe, with the young among the more at risk. Several European projects have demonstrated the effectiveness of using e-tools in suicide prevention particularly for hard-to-reach…
- Conditions
- Suicide, Depression, Psychological Distress, Anxiety Disorders
- Trial name
- E-psYouth (NCT04946955)
- Testing
- Application and website with or without promotion
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depressive Symptoms, Conduct Disorder
Intervening Early: Key Adolescent Outcomes
This study follows children into adolescence who were first randomized to intervention condition in infancy.
- Conditions
- Depressive Symptoms, Conduct Disorder, Anxiety Disorders
- Trial name
- SCOH-A (NCT04168684)
- Testing
- Attachment and Biobehavioral Catch-up (ABC), Developmental Education for Families (DEF)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Delaware
Depression in Adolescence, Anxiety
Promoting Mental Health Among At-risk Adolescents in Malaysia
The primary objective of this trial is to evaluate a school-based intervention designed to promote mental health among at-risk adolescents from low-income communities in Malaysia.
- Trial name
- MyHeRo (NCT07138664)
- Testing
- Super Skills for Life program, Study-Skills program
- Where
- 5 sites in Malaysia
- Volunteers
- 428 people
- Sponsor
- University of Roehampton
Postpartum Depression
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers
The Specific Aim of this study is to conduct a randomized controlled trial to evaluate whether Project REACH (an interpersonal psychotherapy-based intervention) compared with a didactic attention-control program reduces the risk…
- Trial name
- REACH 2 (NCT01482832)
- Testing
- Interpersonal therapy-based treatment
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Depression, Trauma
Online Therapy Youth, Equivalent to Treatment As Usual?
With growing waiting lists in specialized youth mental health care (sGGZ) and shortages of care staff, finding creative solutions to respond to this scarcity issue is important.
- Conditions
- Depression, Trauma, Compulsive Disorder, Anxiety
- Trial name
- NCT06617663
- Testing
- EMDR, ACT
- Where
- Netherlands
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GGZ Noord-Holland-Noord
Conduct Disorder, Depression
Randomized Control Trial of an Animal-Assisted Intervention With Adjudicated Youth
The project involves testing the efficacy of an animal-assisted intervention (AAI). The AAI consists of a 10-week program in which adjudicated adolescents train shelter dogs and will be compared to a dog walking control group…
- Conditions
- Conduct Disorder, Depression, Anxiety
- Trial name
- NCT01594606
- Testing
- Animal-assisted intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Inflammation, Psychosocial Functioning
Mindfulness Meditation Neuroimaging Study for Undergraduates
This study is designed to test the effectiveness of mindfulness meditation intervention classes on psychosocial health outcomes.
- Conditions
- Inflammation, Psychosocial Functioning, Depression, Anxiety
- Trial name
- NCT05304052
- Testing
- Mindfulness Meditation classes
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depressive Disorder
Interpersonal Counseling (IPC) for Treatment of Depression in Adolescents
The aim of this cluster randomized trial is to investigate whether the brief, 1+6 session psychosocial intervention, Interpersonal Counseling (IPC) is more effective than standard professional treatment (ST) in the treatment of…
- Trial name
- IPCAS (NCT03001245)
- Testing
- Interpersonal Counseling, Standard treatment
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Hospital District of Helsinki and Uusimaa