Clinical trials: Adolescent Depression
Depression
A Study on the Intervention Effect of Therapeutic Horticulture Based on the Healing System on Non-suicidal Self-injury in Adolescent Patients With Depression
Non-suicidal self-harm is a serious issue. Adolescents with depression are among the high-risk groups for non-suicidal self-harm behavior.
- Trial name
- NCT07115381
- Testing
- Therapeutic Horticulture, Routine treatment and nursing
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Lei Huang
Suicide, Depression
Attachment Based Family Therapy for Suicidal Adolescents
This study will evaluate the efficacy of attachment based family therapy (ABFT) for treatment of suicidality in adolescents. The study will compare 16 weeks of treatment with ABFT to a control condition Family Enhanced…
- Conditions
- Suicide, Depression, Family Relationships
- Trial name
- NCT01537419
- Testing
- Attachment-Based Family Therapy, Family-Enhanced Non-directive Supportive Therapy
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Drexel University
Adolescent Behavior
Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk…
- Trial name
- ASAP (NCT02272179)
- Testing
- As Safe As Possible, Brite, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Major Depressive Disorder, Mood Disorders
Mechanisms of Rumination Change in Adolescent Depression
This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with…
- Trial name
- RuMeChange (NCT03859297)
- Testing
- Rumination-Focused CBT, Relaxation-based Therapy
- Where
- 3 sites in United States
- Volunteers
- 183 people
- Sponsor
- Ohio State University
Autism Spectrum Disorder
Promoting Resilience in Teens With ASD
Interventions for Autism Spectrum Disorder (ASD) are almost uniformly costly and time-intensive, blunting dissemination of intervention and stymying opportunities to make scalable impact.
- Trial name
- PRITA (NCT04208425)
- Testing
- Project Personality, Sharing Feelings Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Adolescent, Depression
Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD
The purpose of this study is to determine whether it is more effective to treat adolescents, with diagnoses of both depression and substance use disorder, with a treatment addressing the substance use first and then treating the…
- Conditions
- Adolescent, Depression, Substance Use Disorders
- Trial name
- Sequencing (NCT00680966)
- Testing
- Adolescent Coping With Depression/Functional Family Therapy
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Oregon Research Institute
Emotion Regulation, Depression
JoyPop Mobile Mental Health App With Youth
Youth in Canada are in need of novel, innovative approaches to support their mental health and wellbeing. Within this age group, research suggests rates of several mental health difficulties and related hospitalizations have…
- Conditions
- Emotion Regulation, Depression, Anxiety, Stress
- Trial name
- NCT06239519
- Testing
- Usual Practice + JoyPop
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Type 1 Diabetes
Supporting Treatment Adherence Needs in Diabetes
There is an unmet treatment need for depressed adolescents with type 1 diabetes. To address this unmet need, we have designed a new, family-based, cognitive-behavioral intervention to reduce depressive symptoms, improve family…
- Trial name
- STAND (NCT01030471)
- Testing
- Family-based cognitive-behavioral treatment
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anxiety, Depression
Attention Bias Modification Training for Young People
Attention bias modification training (ABMT) is a computer-based attention training programme designed to modify the way a person's attention is directed to mild threats in the environment.
- Trial name
- NCT02270671
- Testing
- ABMT
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Risk Assessment, Resilience, Psychological
Resilience in Adolescent Development
RAD is a 10-year natural history, longitudinal, prospective assessment study of a cohort of 2,500 participants (ages 10-24 years) that will help uncover the socio-demographic, lifestyle, clinical, psychological, and…
- Conditions
- Risk Assessment, Resilience, Psychological, Depression, Mood Disorders
- Trial name
- RAD (NCT03458936)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depressive Disorder, Mental Disorder in Adolescence
A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression
In this study, 60 depressed patients who meet the criteria will randomly be divided into a test group and a control group, with 30 patients in each group.
- Trial name
- NCT05251779
- Testing
- Volatile Oil of Cang-Ai, Bergamot essential oils
- Volunteers
- 60 people
- Sponsor
- Jieqiong Cui
Anxiety Disorder, Depressive Disorder
Internet Transdiagnostic-CBT for Anxiety and Depression in Adolescents
This study represents the first research program to assess the efficacy of transdiagnostic cognitive behavior therapy (T-CBT) delivered via internet for anxiety and depression in adolescents.
- Conditions
- Anxiety Disorder, Depressive Disorder, Emotional Disorder
- Trial name
- NCT04182061
- Testing
- The AMTE protocol
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Nacional de Educación a Distancia
Mental Disorders, Child, Mental Disorder in Adolescence
Equine Assisted Services in Children and Adolescents With Mental Illness
Due to an increasing amount of children and adolescents are suffering from mental illnesses i Sweden. Early preventive psychological interventions are important to avoid a long-time use of medicines.
- Conditions
- Mental Disorders, Child, Mental Disorder in Adolescence, Anxiety Disorders, Anxiety
- Trial name
- EASiCAM (NCT05670990)
- Testing
- Equine assisted therapy
- Where
- Sweden
- Sponsor
- Peter Nymberg
Depression - Major Depressive Disorder, Depressive Episodes
TDM-Guided Treatment With SSRIs in Hospitalized Adults and Children
Depression in childhood and adolescence is a serious and increasing public-health problem associated with profound short- and long-term consequences, including impaired social and educational functioning, increased risk of…
- Trial name
- NCT07478796
- Testing
- Fluoxetine, Escitalopram, Sertralin
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Poznan University of Medical Sciences
Adverse Childhood Experience, Depression / Major Depressive Disorder
Preventive and Personalized Digital Emotion Regulation Skills Intervention to Reduce Depression and Anxiety in Youths With Adverse Childhood Experiences
The present study aims to determine whether a personalized digital psychoeducation intervention (active intervention group) is more effective than self-monitoring of one's mood (control group) in reducing emotion regulation…
- Conditions
- Adverse Childhood Experience, Depression / Major Depressive Disorder, Anxiety Depression, Anxiety
- Trial name
- PREVENT-DERS (NCT07921446)
- Testing
- Lifestyle psychoeducation intervention, Personalized digital psychoeducation intervention on emotion regulation
- Volunteers
- 140 people
- Sponsor
- Institute of Mental Health, Singapore
Anxiety Disorders, Anxiety State
Intergenerational Study of War-Affected Youth
War-related violence is a leading driver of mental disorders and illness affecting children in low- and middle-income countries (LMICs).
- Conditions
- Anxiety Disorders, Anxiety State, Depressive Disorder, Mood Disorders
- Trial name
- ISWAY (NCT06440460)
- Where
- Sierra Leone
- Volunteers
- 804 people
- Sponsor
- Boston College
HIV, Depression
Treatment for Depression Among HIV-Infected Youth
This is a two-phase study that is designed to test a novel behavioral intervention to treat depression in Human Immunodeficiency Virus (HIV) adolescents and young adults.
- Conditions
- HIV, Depression, HIV Infections
- Trial name
- NCT01049789
- Testing
- COMB - Combination Cognitive Behavioral Therapy and Medication Management, TAU - Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder, Repetitive Transcranial Magnetic Stimulation
Individualized dlPFC-NAcc Modulation for Anhedonia in adMDD
This study evaluates a schedule of precise repetitive transcranial magnetic stimulation for depressive adolescent with anhedonia.
- Trial name
- NCT05544071
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xijing Hospital
Involutional Depression, Anxiety Disorders
MRI Study of Brain Activity and Risk for Depression in Adolescents
Anxiety in children of parents with major depressive disorder (MDD) poses a particularly high risk for later-life MDD. In adults, MDD involves dysfunction in prefrontal brain regions that regulate attention to emotional stimuli.
- Trial name
- NCT00047944
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression - Major Depressive Disorder
Efficacy and Safety of Transcranial Alternating Current Stimulation (tACS) in Adolescents With First-episode Depression Who Are Drug-naive: A Randomized, Double-blind, Controlled Pilot Study
To evaluate the efficacy of tACS treatment.To determine whether tACS can accelerate symptom remission, improve clinical response rates, and facilitate the recovery of emotional and cognitive functions through standardized…
- Trial name
- NCT07185464
- Testing
- tACS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University