Clinical trials: Anesthesia, Local
Pain
Use of Local Anesthetic (0.25% Bupivacaine) for Pain Control in Pediatric Cardiac Catheterization
In the Cardiac Diagnostic and Interventional Unit (CDIU) at the Hospital for Sick Children (SickKids), minimally invasive procedures are performed to diagnose and treat a variety of congenital heart defects.
- Trial name
- NCT01133119
- Testing
- Standard of Care, Standard of Care plus bupivacaine
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- The Hospital for Sick Children
Dental Anxiety, Pain
Effect of Therapeutic Play and Virtual Reality Glasses on Pain and Anxiety in Children
Background: A child's first dental experience plays a crucial role in treatment success and in fostering cooperation during future visits.
- Trial name
- NCT07375056
- Testing
- Intervention 1: Therapeutic Play Group, Intervention 2: Virtual Reality Glasses Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Tooth Extraction, Local Anesthesia
Effect of AV Distraction and Acuapoint Stimulation in Pediatric Extraction on Pain and Anxiety
The aim of this study is to evaluate the effectiveness of audiovisual distraction and acuapoint stimulation on anxiety and pain perception during tooth extraction in children.
- Conditions
- Tooth Extraction, Local Anesthesia, Anxiety, Pain
- Trial name
- AV Acupoint (NCT07371442)
- Testing
- Acualief, Audiovisual, TELL SHOW DO
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anesthesia, Anxiety
Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia
The present study will evaluate the effectiveness of Buzzy Bee in reducing pain and physiological responses during maxillary buccal infiltration in children aged 5-7 years compared with a conventional injection protocol.
- Conditions
- Anesthesia, Anxiety, Pain, Children
- Trial name
- NCT07886333
- Testing
- Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Postoperative Pain, Analgesic Efficacy
Local Anesthetic in Total Knee Arthroplasty (TKA): Volume Versus Concentration
In a randomized, double-blind, cross-over trial, 48 patients scheduled for total knee arthroplasty with placement of an intracapsular catheter will be randomized to receive bolus injection of ropivacaine in high volume/low…
- Trial name
- NCT01012232
- Testing
- 20 mL ropivacaine 5 mg/mL, 10 mL ropivacaine 10 mg/mL
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Lundbeck Foundation
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pain Management, Local Anaesthesia
Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children
The aim of this study is to determine the effectiveness of DentalVibe (DV) in reducing injection pain and anxiety associated with local anaesthesia in paediatric patients.
- Trial name
- NCT03445182
- Testing
- Local anaesthesia with conventional syringe, Local anaesthesia with conventional syringe + Dentalvibe
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Anesthesia, Local
Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean Delivery
Postoperative pain is considered one of the major problems after abdominal operations, so proper pain control is one of the main issues in clinical practice.
- Trial name
- NCT04748224
- Testing
- Bupivacaine 0.25% Injectable Solution, bupivacaine plus dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tuberculosis
Local Anesthesia and Tuberculin Skin Test in Infants and Children
The use of local anaesthesia efficiently reduces pain due to needle puncture. However, when tuberculin skin test is performed it is the skin reaction to tuberculin injection that is studied.
- Trial name
- NCT00309673
- Testing
- lidocaine / Prilocaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anatomic Abnormality, Anatomy
Evaluation of a Femoralis, n Femoralis and m Iliopsoas Tendon Sonoanatomy According to Age Groups in Children
This study aims to examine the sonoanatomy of the inguinal region in children according to age groups.
- Conditions
- Anatomic Abnormality, Anatomy, Pediatrics, Anatomic Landmarks
- Trial name
- NCT04860479
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Pain
Assessing the Benefits of the Vibraject Attachment
Behavioral and physiologic observations suggest that the injection of local anesthetic is among the most feared or anxiety producing procedures during dental intervention.
- Trial name
- Vibraject (NCT01227525)
- Testing
- Vibraject
- Volunteers
- 90 people
- Sponsor
- Keith Allen, PhD
Anesthesia, Ostomy
Transversus Abdominis Plane Block in Children Undergoing Ostomy Surgery
The primary objective of this study is to determine if the use of Transversus Abdominis Plane (TAP) blocks reduce early postoperative opioid requirements.
- Trial name
- NCT01136668
- Testing
- Transversus Abdominis Plane Block, Standard
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- The Hospital for Sick Children
Appendectomy, Laparoscopic, Pediatric Anesthesia
Rectus Sheath Block and Local Wound Infiltration in Pediatric Laparoscopic Appendectomies
Laparoscopic appendectomy surgeries are among the most commonly performed procedures in childhood. However, they are associated with moderate to severe postoperative pain.
- Conditions
- Appendectomy, Laparoscopic, Pediatric Anesthesia, Nerve Block/Methods, Regional Anesthesia
- Trial name
- NCT06913205
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Bursa City Hospital
Acute Pain, Pain, Postoperative
Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
We hypothesize that patients who receive a supraclavicular block via Angiocath, placed intra-operatively and dosed post-operatively following neurologic examination, will have lower pain scores, lower use of intravenous morphine…
- Trial name
- NCT02210429
- Testing
- Elbow Fracture Fixation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Injection Pain, Local Anesthesia
Efficacy of Virtual Reality in Reducing Injection Pain and Anxiety During Local Anesthesia in Children
The aim of this study is to determine the efficacy of a virtual reality (VR) device in reducing injection pain and anxiety associated with local anesthesia in pediatric dental patients.
- Trial name
- NCT03772483
- Testing
- Local anesthesia with conventional syringe, Local anesthesia with conventional syringe + VR device
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Anesthesia, Local
Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population
The primary aim of this study is to evaluate the pharmacokinetics of serum ropivacaine concentrations following erector spinae plane peripheral nerve blocks in the pediatric population.
- Trial name
- NCT04298099
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor College of Medicine
Hip Dysplasia
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1.
- Trial name
- PILA PAO (NCT06519955)
- Testing
- Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Michael C Willey
Laparoscopic Colon Resection, Perioperative Analgesia
Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections
The aim of this study is to investigate the analgesic effects of intraperitoneal lignocaine (IPL) compared with intravenous lignocaine (IVL) after laparoscopic colon resections.
- Trial name
- NCT03105193
- Testing
- IV Saline bolus and infusion, IP Saline bolus and infusion, IV lignocaine bolus and infusion
- Where
- New Zealand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Arthroplasty, Replacement, Knee
Intraarticular Analgesia After Total Knee Arthroplasty, a Randomised Study
The study aims to compare two different kinds of pain treatment after total knee replacement (operation with artificial knee joint): 1) a large local injection in and around the knee, supplemented with injection the day after, or…
- Trial name
- NCT00269529
- Testing
- femoral nerve block, knee infiltration and injection via catheter
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Anxiety, Pain
A Novel Approach in Reducing Dental Pain and Anxiety of Pediatric Patient During Local Anesthesia.
The aim of this study is to determine the efficacy of sweet in compare to virtual reality (VR) device in reducing injection pain and anxiety associated with local anesthesia in pediatric dental patients.
- Trial name
- NCT04585061
- Testing
- Lidocaine Hydrochloride, Virtual reality device (Harga Miniso Vr Glass 3d terbaru), Xylitol
- Where
- Saudi Arabia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University