Clinical trials: Atherosclerotic Plaque
To Assess the Feasibility of CT-derived FFR, WSS and TPF on Coronary Atherosclerotic Plaque
Evaluation of FFR, WSS, and TPF Using CCTA
To assess the feasibility of CT-derived computed fractional flow reserve (FFRCT), wall shear stress and total plaque force on coronary atherosclerotic plaque and to collect the preliminary data to apply those parameters for the…
- Trial name
- NCT01857687
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Acute Coronary Syndrome, Myocardial Infarction
Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic
The EMERALD trial is a multinational, multicenter study. The patients presented with AMI/definite evidence of plaque rupture and had underwent coronary CT angiography from 1 month to 2 year prior to the event will be…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Plaque, Atherosclerotic, Rupture, Spontaneous
- Trial name
- EMERALD (NCT02374775)
- Where
- 2 sites in South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Hospital
Vascular Disease, Diabetes
A Proposed Study of Atherosclerotic Plaques in Leg Arteries
Biofilm has been identified as the major bacterial phenotype contributing to atherosclerosis. It has become very important to evaluate atherosclerosis and the role of biofilm using advanced technologies.
- Trial name
- NCT01803126
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Southwest Regional Wound Care Center
Atherosclerotic Disease, Plaque, Atherosclerotic
Natural History of Carotid Plaque as Determined by 3D Ultrasound
This proposed follow-up study aims to recruit participants from the original BioImage cohort for a one-time follow-up examination.
- Conditions
- Atherosclerotic Disease, Plaque, Atherosclerotic, Heart Diseases, Stroke
- Trial name
- BioImage2 (NCT03314818)
- Testing
- Ultrasound 3D Imaging
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Pieter Muntendam
Carotid Artery Stenosis, Carotid Atherosclerosis
Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis
This prospective observational study aims to compare photon-counting detector computed tomography angiography (PCD-CTA) with conventional energy-integrating detector computed tomography angiography (EID-CTA) for the assessment of…
- Conditions
- Carotid Artery Stenosis, Carotid Atherosclerosis, Carotid Atherosclerotic Plaque
- Trial name
- NCT07762664
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Ultrasound
Evaluation of the Vulnerable Carotid Atherosclerotic Plaque: A Clinical Multicenter Study
Evaluation of carotid plaque vulnerability based on ultrasound imaging features， proteomics and metabolomics: a clinical multicenter study
- Trial name
- NCT05849909
- Where
- China
- Volunteers
- 57 people
- Sponsor
- huang pintong
Atherosclerotic Plaque
Reduced Radiation Dose and IR-impact on Coronary Calcium Quantification
Evaluation of reduced radiation dose iterative reconstruction reconstructions for calcium scoring compared to full dose filtered back projection reconstructions
- Trial name
- NCT04267094
- Testing
- Iterative reconstruction at reduced radiation dose
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Pennsylvania
Arteriosclerosis
Magnetic Resonance Imaging of Narrowed Arteries
This study will compare four methods of imaging arteries: angiography (x-ray picture) intravascular ultrasound (ultrasound from inside the artery) magnetic resonance imaging (MRI) from outside the body MRI using an antenna to…
- Trial name
- NCT00029575
- Testing
- Surgi-Vision Guidewire Coil
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Efficiency of AI Reporting (EAIR).
While there are features on a CCTA that are correlated with plaque vulnerability and can be reported on, this is not always done.
- Trial name
- EAIR (NCT05583968)
- Where
- United Kingdom
- Sponsor
- London North West Healthcare NHS Trust
Coronary Artery Disease, Plaque, Atherosclerotic
Fractional Flow Reserve (FFR) Versus Instant Wave-Free Ratio (iFR)
Comparison of Fractional Flow Reserve versus instant Wave-Free Ratio for assessment of coronary artery stenosis severity in routine practice To compare FFR to iFR in arbitrary consecutive patients referred for percutaneous…
- Trial name
- NCT01559493
- Where
- 5 sites in United States, Belgium and 3 more
- Volunteers
- 200 people
- Sponsor
- NHS National Waiting Times Centre Board
Vulnerable Atherosclerotic Plaque
Plaque Calcium Characterization and Ruptured Plaques
Recently, ultrashort echo time (UTE) MR, which allows detection of the ultrashort T2 components, has been used to image plaque calcification in ex vivo carotid and coronary arteries.
- Trial name
- NCT03849521
- Testing
- MRI
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Li Min
Atherosclerosis
Influenza A VIRus and Destabilization of Atherosclerotic Carotid Plaques
Atherosclerosis is the main cause of cardiovascular diseases and is characterized by the accumulation of lipids and inflammatory cells such as macrophages and lymphocytes within the vessel wall of large and medium-sized arteries…
- Trial name
- VIRAL (NCT06217471)
- Testing
- Carotid Endoarterectomy
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- IRCCS Policlinico S. Donato
Myocardial Bridging, Coronary Atherosclerosis
Coronary Myocardial Bridge and Coronary Plaques on MDCT
Myocardial bridging is a condition in which a segment of a coronary artery passes through the heart muscle instead of running on its surface.
- Trial name
- NCT07916272
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University