Clinical trials: Augmentation
Metastatic Malignant Neoplasm in the Spine
Medical Data Collection for the Evaluation of Radiofrequency Ablation and Cement Augmentation for the Treatment of Secondary Metastases to the Spine
This study collects data on the use of radiofrequency ablation and cement augmentation for the treatment of cancer that has spread to the spine (metastases to the spine).
- Trial name
- NCT04751422
- Testing
- Electronic Health Record Review
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- M.D. Anderson Cancer Center
Major Depressive Disorder
Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder
The primary hypothesis is that compared to placebo, 10g of daily creatine monohydrate for eight weeks will be associated with significant increases in frontal lobe phosphocreatine and beta-nucleoside triphosphate (β-NTP)…
- Trial name
- NCT02134808
- Testing
- Creatine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Instrumental Vaginal Births, Oxytocin Augmentation for Labor
The Swedish Birth Seat Trial
The purpose of this study is to determine whether birth on a birthing seat will effect numbers of instrumentally assisted vaginal births, vaginal traumas, blood loss,use of artificial oxytocin for labour augmentation and fetal…
- Conditions
- Instrumental Vaginal Births, Oxytocin Augmentation for Labor, Maternal Blood Loss, Perineal Outcomes
- Trial name
- NCT01182038
- Testing
- BirthRite birthing seat
- Where
- Sweden
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- Helsingborgs Hospital
Lung Diseases, Obstructive, Pulmonary Disease, Chronic Obstructive
Physical Activity Augmentation Using Pedometers During Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease
Patients with chronic lung diseases such as Chronic Obstructive Pulmonary Disease (COPD), who perform regular physical activity, have improved health and wellbeing compared with those who do little exercise.
- Conditions
- Lung Diseases, Obstructive, Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic
- Trial name
- NCT01719822
- Testing
- Yamax Digi-Walker CW-700
- Where
- United Kingdom
- Volunteers
- 155 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Depression
PERsonalized Mood Augmentation Trial for Depressed Mood
The goal of this open-label single-arm study is to test personalized behavioral intervention for depressed mood.
- Trial name
- PERMA (NCT05662254)
- Testing
- Personalized Behavioral Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Chronic Kidney Disease, Pediatric
The Cardiovascular Comorbidity in Children With Chronic Kidney Disease Study
Children and adolescents with chronic kidney disease (CKD) are at high risk for cardiovascular (CV) morbidity and mortality. Recent studies suggest that pediatric patients with even moderately impaired kidney function may be…
- Conditions
- Chronic Kidney Disease, Pediatric, Cardiovascular Disease
- Trial name
- 4C (NCT01046448)
- Where
- 50 sites in Austria, Belgium and 13 more
- Volunteers
- 650 people
- Sponsor
- Heidelberg University
Implant Complication
Modified Shell Technique Versus Onlay Bone Graft in Anterior Maxilla
Amount of bone volume and (width and height): Will be measured using linear measurements from CBCT after 6 month from implant insertion.
- Trial name
- NCT03663439
- Testing
- modified shell technique
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Jaw, Edentulous, Jaw, Partially Edentulous
Prospective Registry of Immediate/Delayed Loading of Implants in the Cranial Bone-grafted Severely Atrophic Jaw
Edentulism is often associated with a negative psychosocial impact. The concept of prosthetic rehabilitation in which a prosthesis is supported by osseointegrated implants, was first introduced in the late 1960s by Brånemark et…
- Trial name
- ILICRAN (NCT02664298)
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Sint-Jan AV
Alveolar Ridge Augmentation
Effect of Low Level Laser Teraphy on Bone Regeneration
This randomized controlled split-mouth clinical trial study was designed to evaluate the effects of low-level laser therapy on bone healing in patients with bilateral sinus lifting and simultaneous dental implant application.
- Trial name
- NCT03179683
- Testing
- Diode laser application
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ugur GULSEN
DELAYED LABOUR
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women
Obesity is one of the biggest public health problems of the 21st century as it increases the risk of many co-morbid medical conditions.
- Trial name
- NCT03604874
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Assiut University
Neurogenic Bladder Disorder, Spina Bifida
Complications of Bladder Augmentation in Children
The goal of this observational study is to describe the complications in participants who underwent enterocystoplasty in childhood.
- Conditions
- Neurogenic Bladder Disorder, Spina Bifida, Complications of Surgical Procedures or Medical Care, Child, Only
- Trial name
- AVPED (NCT06733194)
- Where
- France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Clermont-Ferrand
Tourette Disorder, Chronic Tic Disorder
Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo
Expert reviews and practice parameter papers recommend behavior therapy as a first-line intervention for youth with chronic tic disorders (CTDs) with mild-to-moderate tic severity.
- Trial name
- DCS+HRT (NCT02582515)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Neurogenic Bladder
Augmentation Cystoplasty Using an Autologous Neo-Bladder
Subjects with neurogenic bladder secondary to spina bifida refractory to medical treatment will be enrolled. The hypothesis is that augmentation cystoplasty using an autologous neo-bladder construct will significantly increase…
- Trial name
- NCT00419120
- Testing
- Autologous neo bladder construct
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tengion
Soft Tissue Augmentation at Dental Implants
Assessment of Soft Tissue Thickness Following Utilization of Buccal Pad of Fat Versus Platelet-rich Fibrin for Covering Zygomatic Implants: A Randomized Clinical Trial
Would buccal pad of fat be comparable to platelet rich fibrin for Zygomatic implant coverage as a step for reconstruction of atrophic posterior maxilla, in terms of peri-implant soft tissue thickness and avoiding complicated…
- Trial name
- NCT07562334
- Testing
- Coverage with PRF for Zygomatic implant placed
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Lateral Sinus Lifting
Lateral Sinus Augmentation Utilizing Bovine Bone Mixed with Platelet-rich Fibrin
Background: In sinus augmentation procedure, graft resorption remains a major dilemma of various graft materials. Objective: To estimate the graft volume changes following lateral sinus augmentation utilizing cone beam computed…
- Trial name
- NCT06810921
- Testing
- lateral sinus lift
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- University of Baghdad
Major Depressive Disorder (MDD)
Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression（SMART-I)
This project aims to investigate the effectiveness of existing common antidepressants in adolescents with MDD who did not respond to their first treatment.
- Trial name
- SMART-I (NCT07011693)
- Testing
- Sertraline, Agomelatine, Aripiprazole
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinyu Zhou
Alveolar Bone Grafting
E-Polycaprolactone-Containing Membrane in Alveolar Bone Regeneration
This study aimed to evaluate the effectiveness of synthetic polycaprolactone (PCL) bioscaffold membranes used for alveolar augmentation in maxillofacial surgery for increasing the amount of newly formed bone after…
- Trial name
- NCT06627621
- Testing
- Alveolar Ridge Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- cem üngör
Sinus Lifting
Titanium Prepared Platelet-rich Fibrin in Bone Regeneration in Lateral Window Maxillary Sinus Augmentation
This trial aims to evaluate the effect of the sole use of T-PRF in bone formation process as applied in maxillary sinus floor elevation in comparison to traditional T-PRF/bone graft combination.
- Trial name
- NCT06135077
- Testing
- T-PRF alone, T-PRF/Xenograft
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Hams Hamed Abdelrahman
Attention Deficit Disorder
Effect of Omega-3 Fatty Acid on Cortical Function in ADHD
The study hypothesis is that DHA is more effective than placebo in increasing brain activation and reducing symptoms in psychostimulant-free children with ADHD.
- Trial name
- NCT01883817
- Testing
- DHA Omega-3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Edentulous Jaw
Horizontal Augmentation With Deproteinized Bovine Bone Mineral Alone or in Combination With Particulate Autogenous Bone
Background: Placement of oral implants is frequently compromised due to atrophy of the alveolar process. Lateral ridge augmentation with an autogenous bone block is frequently necessary to increase the width of the alveolar…
- Trial name
- NCT04755166
- Testing
- Lateral ridge augmentation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- NU-Hospital Organization, Sweden