Clinical trials: Behavior and Behavior Mechanisms
Pediatric Obesity, Behavior and Behavior Mechanisms
Neuro-cognitive Impact of Juvenile Obesity
Recent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementation of memory and emotional…
- Conditions
- Pediatric Obesity, Behavior and Behavior Mechanisms, Emotions
- Trial name
- OBETEEN (NCT03776513)
- Testing
- an MRI examination
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Child Behavior Problem
Effectiveness of the Social-Emotional Prevention Program Enhanced Version
The current study is intended to investigate the effectiveness of the Social-Emotional Prevention Program enhanced version (SEP+) for increasing preschoolers' social-emotional competencies and reducing their risk for behavior…
- Trial name
- SEP+ (NCT05057728)
- Testing
- Social-Emotional Prevention Program enhanced version
- Where
- Romania
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Obesity, Childhood, Binge Eating
Project REST: Regulation of Eating and Sleep Topography
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for…
- Conditions
- Obesity, Childhood, Binge Eating, Sleep, Self-regulation
- Trial name
- NCT04057716
- Testing
- Sleep restriction, Sleep extension
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Attention Deficit-Hyperactivity Disorder
Biomarker Research in ADHD: the Impact of Nutrition
Attention deficit hyperactivity disorder (ADHD) is the most common childhood behavioural disorder, causing significant impediment to a child's development. The exact aetiology of ADHD is still unknown.
- Trial name
- BRAIN (NCT03440346)
- Testing
- Few-foods diet
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Wageningen University
Depression
Activating and Connecting Teens (ACT) Study
National data indicate over 650,000 children and adolescents are exposed to physical, sexual, or emotional abuse or physical or emotional neglect each year.
- Trial name
- ACT (NCT03438656)
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Washington
Physical Activity, Sedentary Behavior
Teen Mom Study Feasibility Trial
The proposed multicomponent digital health intervention has the potential to significantly impact the trajectory of maternal health in a rural, pregnant, Black adolescent population with the highest risks for cardiometabolic…
- Conditions
- Physical Activity, Sedentary Behavior, Gestational Weight Gain, Social Determinants of Health
- Trial name
- NCT05843903
- Testing
- #BabyLetsMove
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Autism Spectrum Disorder
Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorders
This study is a prospective, multicenter, randomized, single-blind controlled trial to enroll 200 children with autism spectrum disorders (ASD).
- Trial name
- NCT05927792
- Testing
- repeated transcranial magnetic stimulation (continuous theta-burst stimulation)
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Eating Behavior
Mother-Baby Study - Caloric Compensation Index (COMPX)
The study will test a model of biobehavioral mechanisms involved in the development of a system of emotion, attachment, and nutritive intake in the mother-infant dyad and the association of this system with maternal feeding…
- Trial name
- NCT06072664
- Testing
- Caloric Compensation Index (COMPX)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Widespread Pain, Stress, Psychological
Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain
Chronic widespread pain (CWP) is a common chronic pain condition in youth and often associated with significant pain-related and psychosocial impairment.
- Conditions
- Chronic Widespread Pain, Stress, Psychological, Stress, Physiological
- Trial name
- NCT04488757
- Testing
- functional Magnetic Resonance Imaging (fMRI), Allostatic Load Composite
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Major Depressive Disorder, Mood Disorders
Mechanisms of Rumination Change in Adolescent Depression
This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with…
- Trial name
- RuMeChange (NCT03859297)
- Testing
- Rumination-Focused CBT, Relaxation-based Therapy
- Where
- 3 sites in United States
- Volunteers
- 183 people
- Sponsor
- Ohio State University
Binge Eating Behaviour, Eating Disorders
Biobehavioral Mechanisms of Activity and Loss of Control Eating in Children
Loss of control eating in children and adolescents is associated with a host of negative physical and psychological health outcomes and a prognostic marker for development of eating disorders.
- Conditions
- Binge Eating Behaviour, Eating Disorders, Physical Activity, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07823153
- Testing
- Go/No-go task, Visual food task, Emotion regulation task
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Opioid Use Disorder, Dual Diagnosis
Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness
Homelessness severely affects health and well-being and is particularly negative for youth. Between 70-95% of youth experiencing homelessness (YEH) report problem substance use and 66-89% have a mental health disorder.
- Conditions
- Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence
- Trial name
- NCT06311838
- Testing
- Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Neuropsychiatric Symptom
Dissecting Immunological and Autoimmune Mechanisms of Neuropsychiatric Diseases
The goal of this observational cohort study is to investigate the role of immune system in neuropsychiatric symptoms (NPS) and to identify immunological biomarkers that may improve the diagnosis, prognosis, and future treatment…
- Trial name
- DIAMOND (NCT07791212)
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- King's College London
Behavior and Behavior Mechanisms, Health Knowledge, Attitudes, Practice
Learning and Living With Wildfire Smoke
The proposed intervention in this Youth Participatory Action Research (YPAR) proposal will improve knowledge and awareness of the health impacts of air pollution exposure, will elevate the youth voice, improve youth self-efficacy…
- Trial name
- NCT06322966
- Testing
- Air Action Curriculum
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Washington
Behavior and Behavior Mechanisms
Fathers Raising Responsible Men (FRRM): Addressing Sexual Health
While existing teen pregnancy prevention efforts have contributed to significant declines in the overall U.S. teen pregnancy rate, teen pregnancy prevention programs specifically targeting adolescent males are limited and sorely…
- Trial name
- FRRM (NCT03429985)
- Testing
- FRRM Intervention
- Where
- United States
- Volunteers
- 382 people
- Sponsor
- Duke University
Behavior and Behavior Mechanisms
Impact of Another Person's Presence on Brain and Behavioral Performance
In a recent study, investigators provided the first neuroscientific data on social facilitation. This neuroimaging study, performed in the macaque monkey, shows a marked improvement in performance in a simple task when a congener…
- Trial name
- SOFEE (NCT03453216)
- Testing
- neuropsychological tests
- Where
- France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
ADHD
Multimodal Magnetic Resonance Imaging Study on the Neural Mechanisms of Remission in Children With ADHD
Attention-deficit/hyperactivity disorder(ADHD) is highly prevalent among children and adolescents and often associated with poor long-term outcomes in adulthood. it is thus a serious public health problem.
- Trial name
- NCT05229627
- Testing
- MPH, ATX
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Behavior and Behavior Mechanisms
A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents
The purpose of this study is to test the feasibility and efficacy of a triadic intervention designed to target both healthcare providers and parents in order to prevent adolescent sexual risk behavior in Latino and African…
- Trial name
- NCT01326806
- Testing
- Families Talking Together, Active Control on Hygiene & Nutrition
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- New York University