Clinical trials: Bone Injuries Joints
Osteoarthritis, Osteosarcoma
Clinical Orthopaedic Data Bank (Acute and Chronic)
Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF)…
- Conditions
- Osteoarthritis, Osteosarcoma, Scoliosis, Cerebral Palsy
- Trial name
- NCT00411060
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- University of Florida
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Tibial Fractures, Intra-Articular Fractures
Management of Traumatic Bone Defects in Tibial Plateau Fractures With Antibiotic-Impregnated Biodegradable Calcium Sulfate Beads: A Prospective Clinical Trial
This is a prospective clinical trial of tibial plateau fractures treated with internal fixation and a calcium sulfate graft which can be mixed with antibiotics and molded into various bead sizes for implantation into bone…
- Conditions
- Tibial Fractures, Intra-Articular Fractures, Fracture Fixation, Internal
- Trial name
- NCT02456194
- Testing
- Calcium Sulfate + Antibiotics + Internal Fixation
- Where
- 5 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Ross Leighton
Osteoarthritis
Developing Allogeneic Musculoskeletal Therapies
The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other…
- Trial name
- NCT06167928
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Keele University
Defect of Articular Cartilage, Cartilage Injury
Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair
This is a proof-of-concept study to determine the safety and efficacy of a novel device to increase the reparative capacity of the knee.
- Conditions
- Defect of Articular Cartilage, Cartilage Injury, Osteoarthritis, Knee
- Trial name
- AURA (NCT02696876)
- Testing
- Arthroscopic synovial brushing, Microfracture
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- University of Leeds
Recurrent Shoulder Dislocations
Arthroscopic Rotator Interval Closure in Shoulder Instability Repair
Study Title: Arthroscopic rotator interval closure in shoulder instability repair - a prospective study Objective: To evaluate the effect of arthroscopic rotator interval closure (ARIC) on patients with recurrent shoulder…
- Trial name
- NCT00901797
- Testing
- Arthroscopic Bankart repair, ABR+ARIC
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cartilage Loss, Microfracture
Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects
The study will examine clinical and radiographic outcomes of microfracture surgery (a common technique to address isolated areas of cartilage loss) in the knee used with or without unloader bracing.
- Trial name
- Mfxbracing (NCT02016300)
- Testing
- Unloader Bracing, Non-Bracing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Opioid Use, Pain, Postoperative
Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery
The purpose of this randomized clinical trial is to determine the effectiveness of Battlefield Acupuncture (BFA) in addition to usual post-surgical shoulder physical therapy compared to a standard shoulder rehabilitation program…
- Conditions
- Opioid Use, Pain, Postoperative, SLAP Lesion, Bankart Lesion
- Trial name
- NCT03525275
- Testing
- Battlefield Acupuncture, Post-surgical shoulder protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Keller Army Community Hospital
Defect of Articular Cartilage, Osteoarthritis
Comparison of Efficacy and Safety of Microfracture and Modified Microfracture
This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture to prove the non-inferiority of the modified microfracture using…
- Conditions
- Defect of Articular Cartilage, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539030
- Testing
- Microfracture, CartiFill
- Where
- 12 sites in South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Hip Dislocation, Femur Head Necrosis
Investigation of the Femoral Shortening Osteotomy in the Developmental Dislocation of the Hip (FSODDH)
Although older children and high dislocations may be more likely to require a femoral shortening osteotomy, the ultimate decision about whether or not to shorten a given femur should depend on the ease of femoral head reduction…
- Trial name
- FSODDH (NCT02633904)
- Testing
- Osteotomy, Non-osteotomy
- Volunteers
- 200 people
- Sponsor
- He Jin Peng
Ankle Fracture - Medial Malleolus
Medial Malleolus: Operative Or Non-operative
Medial malleolus: Operative Or Non-operative (MOON study) Ankle fractures are a common Orthopaedic trauma presentation, accounting for approximately 10% of the workload.
- Trial name
- MOON (NCT03362229)
- Testing
- Fixation, Non-fixation
- Where
- United Kingdom
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Colles' Fracture
SOLID-Effect of Risedronate Sodium at Distal Radius in Colle's Fracture.
The purpose of this study is to evaluate the efficacy and safety of risedronate sodium (Actonel®) after a wrist fracture in postmenopausal women.
- Trial name
- SOLID (NCT00460733)
- Testing
- Risedronate sodium, Calcium & Vitamine D3
- Where
- Brazil
- Volunteers
- 141 people
- Sponsor
- Sanofi
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
Distal Radius Fractures, Fracture Dislocation
Ultrasound Guided Hematoma Block in Distal Radius Fractures
This study will investigate the effectiveness of analgesia of ultrasound hematoma block compared to 'blind' hematoma block in patients with dislocated distal radius fracture.
- Conditions
- Distal Radius Fractures, Fracture Dislocation, Dislocated Wrist, Dislocated Radius
- Trial name
- NCT06193915
- Testing
- Ultrasound guided hematoma block., Blind hematoma block
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Frisius Medisch Centrum
Shoulder Dislocation
Absorption Rate and Bone Ingrowth of Absorbable Anchors Used in Shoulder Dislocation
This study aims to analyze the absorption rate of Pushlock anchors and Gryphon anchors and the bone ingrowth of the anchor channel by consulting the postoperative CT images of patients with recurrent shoulder dislocation…
- Trial name
- NCT04977505
- Testing
- pushlock, gryphon
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Alveolar Cleft, Distraction of Bone
Evaluation of the Efficiency of Bone Born Intra Oral Distractor for Closure of Wide Alveolar Cleft
The study aimed to determine efficiency of Bone-Born Intraoral Distractor on wide Alveolar cleft patients
- Trial name
- BBID-WAC (NCT07306429)
- Testing
- Bone-borne Intra oral distractor
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Hemifacial Microsomia, Distraction of Bone
Evaluation of Effect of Bone Marrow Aspirate Concentrate on Distracted Mandibular Bone Properties
Maxillofacial Distraction Osteogenesis (DO) has a lot of draw backs; mostly related to long distraction and consolidation time. Rapid rate DO was proposed to decrease the distraction time to avoid consequences of long procedure.
- Trial name
- NCT03861650
- Testing
- Bone Marrow Aspirate Concentrate, Saline
- Volunteers
- 12 people
- Sponsor
- Yasser Mohamed Nabil Ahmed Khirat El Hadidi
Growth Plate Injury
Molecular Modulation of the Growth Plate
The researchers are trying to identify molecular mechanisms that control growth plate mediated limb growth and identify agents that can be used to enhance or slow growth.
- Trial name
- NCT03501589
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Colles' Fracture
Sonographic Assessment of Reduction in Colles' Fracture
Colles fractures are a common type of wrist fracture that often requires manipulation in the Emergency Department. Currently xrays are used to assess whether this has been successful, which are done once the plaster cast has been…
- Trial name
- SONAR (NCT02353065)
- Testing
- Ultrasound imaging, Bedside x-ray
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Simon Richards
Osteoarthritis, Pain
Patellar Resurfacing in Total Knee Arthroplasty
Background: The best treatment of the patella during total knee arthroplasty (TKA) is controversial. The implantation of a patellar component adds to the operation time and the costs of the operation.There is a huge variation as…
- Trial name
- NCT00553982
- Testing
- Patellar component, No patellar component
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Sykehuset Innlandet HF