Clinical trials: Brain Activity
Concussion, Brain, Concussion, Mild
Mobile Subthreshold Exercise Program for Concussion--R01
Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue for weeks or months.
- Conditions
- Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache
- Trial name
- MSTEP-R01 (NCT04688255)
- Testing
- MSTEP, Stretching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Cognitive Function
The Cognitive Functioning of Young Athletes Including Bioelectrical Brain Function
The project focuses on two central issues: 1. The impact of intensity of sport on the cognitive functioning and brain waves of children in late childhood (10-12 years old); 2.
- Trial name
- NCT04753047
- Testing
- No intervention
- Where
- 2 sites in Poland
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Dementia
Group Digital Gaming: Experiences of Older Adults Living With Dementia in an Activity for Cognitive Impairment
The study examines the effects of a group digital gaming intervention on cognitive function, mood, and behaviors in people with early to moderate levels of dementia, using Obie Technology by employing a pretest and posttest…
- Trial name
- PLwD (NCT07541144)
- Testing
- Group-Based Digital Gaming
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Mason University
Cerebral Palsy, Motor Activity
Development of Horse-Riding Program Model for Children With Cerebral Palsy
The purpose of this study is to develop healing riding algorithm applicable in rural riding centers and to apply this to children with cerebral palsy.
- Trial name
- NCT03041818
- Testing
- Horseback riding therapy
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Pediatric Brain Tumor, Cognitive Impairment
Fitness to Aid the Brain and Cognitive Skills
The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise…
- Trial name
- Fit ABCS (NCT05367076)
- Testing
- Web-based Aerobic Exercise Program
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- The Hospital for Sick Children
Gait Disorders, Neurologic, Atypical Parkinson Disease
Brain Activity During Complex Walking in People With Atypical Parkinsonian Syndromes
Every-day life means being part of a complex environment and performing complex tasks that usually involve a combination of motor and cognitive skills.
- Conditions
- Gait Disorders, Neurologic, Atypical Parkinson Disease, fNIRS, Aging
- Trial name
- NCT06906276
- Testing
- Assessment of brain activity with fNIRS and behavioural assessments (motor, motor-cognitive and cognitive) during three complex walking conditions.
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy, Cerebral Palsy (CP)
Validity Assessment of Sensors for Movement Tracking With Children/Youth With Diverse Neuromotor Abilities
The overall goal of this study is to establish the clinical utility and accuracy of markerless motion captures systems for tracking therapy exercises and movement during game play. Specific aims are: 1.
- Trial name
- MOCAP (NCT07360171)
- Testing
- Validity Assessment of Sensors for Movement Tracking With Children/Youth With Diverse Neuromotor Abilities
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Ischemic Attack, Transient
Cognitive and Physical Functions in Patients With Transient Ischemic Attack. A Randomized Controlled Trial of Physical Activity on Prescription up to One Year After the Event
The purpose of this study is to determine whether Physical Activation on Prescription can help patients with TIA to become more physically active.
- Trial name
- NCT01509924
- Testing
- Physical activation on Prescription
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Tiohundra AB
Dementia, Psychomotor Agitation
Objective Assessment of Behavioral Associations of Patients With Dementia
It is generally acknowledged that patients with dementia are best cared for at home. However, outbursts of various behavioral disturbances, e.g., combativeness, appear in most cases and often necessitate institutionalization.
- Trial name
- NCT02617056
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Concussion
Cervicovestibular Physiotherapy and Aerobic Exercise in Concussion
Sport concussions are among the most commonly occurring injuries in sport and recreation and pose significant public health implications for Canadians.
- Trial name
- NCT02988323
- Testing
- Cervicovestibular Physio (CV PT), Low-Level Aerobic Exercise (LLAE), Combination (LLAE and CV PT)
- Volunteers
- 96 people
- Sponsor
- Sport Injury Prevention Research Centre
Overweight, Obesity
Brain Breaks Exercise Videos for Overweight and Obese Children
This randomized controlled study evaluated the effects of a 4-week Brain Breaks® exercise video intervention on physical activity and Transtheoretical Model-related psychosocial factors among overweight and obese children and…
- Trial name
- NCT07826624
- Testing
- Video-Guided Physical Activity Program
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou University
Epilepsy
Study to Evaluate the Safety and Efficacy of USL261 in Patients With Increased Bouts of Seizure Activity in the EMU
This study is designed to evaluate the efficacy, safety, and tolerability of USL261 compared with that of intranasal (IN) placebo for the treatment of intermittent bouts of increased seizure activity.
- Trial name
- NCT01999777
- Testing
- USL261
- Where
- 51 sites in United States, Australia and 6 more
- Volunteers
- 62 people
- Sponsor
- UCB Biopharma S.P.R.L.
Stroke, Brain Injuries
Predictive Indices of Independent Activity of Daily-living in Neurorehabilitation
Postural and balance disorders are common in neurological disorders. They are often associated with reduced mobility and fear of falling, which strongly limit independent activities of daily living (ADL), compromise the quality…
- Conditions
- Stroke, Brain Injuries, Mild Cognitive Impairment, Parkinson Disease
- Trial name
- NCT04691102
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Growth Hormone Deficiency
Phase 2 Study of LUM-201 in Children With Growth Hormone Deficiency (OraGrowtH210 Trial)
This is a multi-national trial. The goals of the trial are to study LUM-201 as a possible treatment for Pediatric Growth Hormone Deficiency (PGHD) and investigate a predictive enrichment marker (PEM) strategy to select subjects…
- Trial name
- OraGrowtH210 (NCT04614337)
- Testing
- LUM-201, rhGH Norditropin® pen (34 µg/kg)
- Where
- 43 sites in United States, Australia and 4 more
- Volunteers
- 104 people
- Sponsor
- Lumos Pharma
Cerebral Palsy (CP), Motor Disability
Complex Rehabilitation Technology Enabled Physical Activity for Children With Motor Delays Via Telehealth in Natural Environments
The primary goal of CP-MOVES is to evaluate 1) the preliminary efficacy of a telehealth-delivered, parent coaching intervention in the use of adaptive standers, on physical activity, sleep, and endurance in young children with…
- Conditions
- Cerebral Palsy (CP), Motor Disability, Motor Delay
- Trial name
- CP-MOVES (NCT07252713)
- Testing
- Stander Use
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Movement Disorder
Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study.
Background: Motor stereotypies are a movement disorder characterized by involuntary, repetitive, and rhythmic movements. These movements have a predictable pattern and seem purposeful, but they serve no obvious function, tend to…
- Trial name
- NCT01037361
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy, Sensitivity
Daily Living Activities in Young Adults With Cerebral Palsy
This study explored the relationship between sensory function and occupational performance in young adults with Cerebral Palsy. Using standardized assessments, researchers compared tactile sensitivity and discrimination between…
- Conditions
- Cerebral Palsy, Sensitivity, Motor Skills Disorders, Activity, Motor
- Trial name
- Palsy202503 (NCT06909994)
- Testing
- individual assessments
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad de Burgos
Alzheimer's Disease, Agitation
Citalopram for Agitation in Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of citalopram for agitation in Alzheimer's dementia.
- Trial name
- CitAD (NCT00898807)
- Testing
- citalopram
- Where
- 8 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- JHSPH Center for Clinical Trials
Epilepsy, Tuberous Sclerosis Complex
A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD
The purpose of this study is to measure if the drug called Everolimus effects mTOR signaling (an electrical activity signal in the brain) in patients with Tuberous Sclerosis Complex (TSC) and Focal Cortical Dysplasia (FCD) with…
- Conditions
- Epilepsy, Tuberous Sclerosis Complex, Focal Cortical Dysplasia
- Trial name
- NCT02451696
- Testing
- Everolimus
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Neurological Diseases or Conditions, Cardiovascular Conditions After Birth
Cereset Research Exploratory Study
The purpose of this study is to evaluate the use of Cereset Research to improve autonomic function in participants with symptoms of stress, anxiety, or insomnia.
- Conditions
- Neurological Diseases or Conditions, Cardiovascular Conditions After Birth, Psychophysiologic Disorders
- Trial name
- NCT03777267
- Testing
- Active CR
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University Health Sciences