Clinical trials: Brain Mapping
Healthy
Magnetic Resonance Imaging of Calculus Problem Solving
This study will use magnetic resonance imaging (MRI) to identify brain regions involved in solving algebraic math problems. It will examine brain activation according to the level of difficulty and the number of steps required to…
- Trial name
- NCT00060658
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Intracranial Aneurysm, Arteriovenous Malformations, Cerebral
Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping
Endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) are becoming increasingly popular due to their less invasive nature and lower risk of complications.
- Trial name
- NCT06588543
- Testing
- Endovascular treatment
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- University Hospital, Ghent
Brain Mapping, Deafness
Areas of Brain Responsible for Understanding American Sign Language
The human brain is made up of two halves called hemispheres. Each half of the brain is responsible for processing different kinds of information.
- Conditions
- Brain Mapping, Deafness, Healthy
- Trial name
- NCT00001782
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer Disease, Dementia
Efficacy of Gamification in Enhancing User Engagement
As part of Phase II of the NIH SBIR grant, the study will conduct a randomized controlled clinical trial in which the MapHabit system's gamification is investigated to determine whether the assistive technology facilitates user…
- Conditions
- Alzheimer Disease, Dementia, Gamification, Assistive Technology
- Trial name
- NCT05422339
- Testing
- The MapHabit system (MHS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MapHabit, Inc.
Epilepsy, Temporal Lobe
Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy
Repetitive transcranial magnetic stimulation (rTMS) may be able to provide a moderately detailed localization of language functions in the brain.
- Trial name
- NCT00001672
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dementia, Agitation
Person- Centred Care Among Nursing Home Patients With Dementia
Dementia is a common and devastating disease in the elderly. No cure exist and there is an increasing need for care. To improve knowledge on how to provide better care for the patients with dementia in nursing homes, the…
- Trial name
- NCT01280890
- Testing
- Staff training using VIPS, Staff training using DCM, Control group
- Volunteers
- 624 people
- Sponsor
- Norwegian Centre for Ageing and Health
Epilepsy in Children
Mapping Epileptic Networks Using Multimodal Imaging
Currently, mapping the epileptogenic zone is based on a comprehensive preoperative assessment involving clinical, imaging and electrophysiological examinations.
- Trial name
- CREIM (NCT06202976)
- Testing
- Secondary data collection
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Imagine Institute
Epilepsy
Presurgical Motor Mapping With Transcranial Magnetic Stimulation (TMS)
The aim of the study is to examine the degree of concordance between presurgical neuronavigation guided TMS (nTMS) and direct cortical stimulation (DCS) in identifying hand motor cortex in adults undergoing epilepsy surgery.
- Trial name
- NCT02741193
- Testing
- The Magstim Rapid2,
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- NYU Langone Health
Epilepsy
Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients
The purpose of this study is to develop a technique for the intraoperative identification of human functional and epileptiform cortex using intrinsic signal imaging.
- Trial name
- NCT00195052
- Testing
- Intrinsic signal imaging of human cortex
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Weill Medical College of Cornell University
Glioblastoma, IDH-wildtype, Glioblastoma
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site.
- Conditions
- Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant
- Trial name
- RECMAP (NCT06273176)
- Testing
- Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
- Where
- 8 sites in United States, Belgium and 3 more
- Volunteers
- 225 people
- Sponsor
- Erasmus Medical Center
Fabry Disease
Native T1 Mapping by Cardiovascular Magnetic Resonance Imaging in Rare Diseases
Fabry Disease (FD) is a rare, X-linked lysosomal storage disorder leading to left ventricular hypertrophy, myocardial fibrosis, arrhythmia and heart failure. Cardiac involvement is the leading cause of death in FD.
- Trial name
- FABRY400 (NCT03199001)
- Where
- 4 sites in Australia, United Kingdom
- Volunteers
- 400 people
- Sponsor
- University College, London
Healthy
MRI Language Studies in Young Children
This study will use magnetic resonance imaging (MRI) to investigate language function in children-that is, how language skills such as naming objects, understanding spoken language and reading are organized in the brain.
- Trial name
- NCT00039845
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy
Magnetic Resonance Imaging in Children and Adults Using Arterial Spin Tagging Techniques
This study will use magnetic resonance imaging (MRI) to examine how blood flow to the brain differs at different ages with the brain is at rest, and during performance of tasks that involve language, memory, motor control, and…
- Trial name
- NCT00034073
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Central Nervous System Neoplasm, Cranial Nerve Disorder
Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System
This phase II trial studies how well gadolinium and ferumoxytol magnetic resonance imaging (MRI) work in diagnosing patients with abnormalities in the central nervous system.
- Conditions
- Central Nervous System Neoplasm, Cranial Nerve Disorder, Metastatic Malignant Neoplasm in the Brain
- Trial name
- NCT03270059
- Testing
- Ferumoxytol, Gadolinium, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- OHSU Knight Cancer Institute
Epilepsy
Pediatric Language and Memory Mapping in Refractory Epilepsy Using Magnetoencephalography
This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy.
- Trial name
- NCT04888637
- Testing
- Baseline MEG Test, Receptive Language Task, Memory Task
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Parkinson Disease, Deep Brain Stimulation
Validation of HaGuide Software Module Accuracy in Mapping STN Boundaries in Parkinson's Disease Patients Who Underwent DBS Procedure
HaGuide version 1.0 (Neuro-Omega Ltd.) is a software module add-on to the FDA cleared Neuro-Omega System (K123796). It was designed to facilitate the use of Neuro-Omega's system by automatically mapping visually the depth of STN…
- Trial name
- NCT03363724
- Testing
- HaGuide version 1.0 software module
- Volunteers
- 103 people
- Sponsor
- Alpha Omega Engineering Ltd.
Parkinson Disease-tremor, Essential Tremor
Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease Before and After MR-guided Focused Ultrasound Thalamotomy for Tremor
A cornerstone in PD and ET research is the investigation of neurophysiological changes as potential bio-markers that could help in tracking disease progression and response to therapy.
- Trial name
- NCT02692183
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Autistic Disorder, Autism, Early Infantile
Using the Digital EEG Spectral Analysis in Assessing Neuroelectrical Processing Abnormalities in Autism
Individuals with Autism Spectrum Disorder will have abnormal DESA® results. Our objective is to use neuroelectrical measures to determine the degree of processing abnormalities in individuals with Autism.
- Conditions
- Autistic Disorder, Autism, Early Infantile, Autism, Infantile, Asperger Syndrome
- Trial name
- NCT00693953
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yellen & Associates, Inc.