Clinical trials: COPD Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
Genetic Polymorphism in Matrix Metalloproteinase 9 in Chronic Obstructive Pulmonary Disease in Sohag University Hospital.
Chronic obstructive pulmonary disease (COPD) is a heterogeneous and complex disease with multiple clinical presentations or phenotypes and remains a highly prevalent condition, causing significant morbidity and mortality…
- Trial name
- NCT06503315
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pulmonary Disease, Chronic Obstructive
Breathing Helium-Hyperoxia During Exercise in Patients With Chronic Obstructive Pulmonary Disease
Regular exercise can help patients with the lung disease, chronic obstructive pulmonary disease (COPD). But COPD patients have a hard time with training because of their breathing.
- Trial name
- NCT01283685
- Testing
- breathing helium-hyperoxia, breathing supplemental oxygen
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- West Park Healthcare Centre
COPD
Effect of Combined Endurance Training on ADL and Walking in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease with related exercise intolerance and marked disability due to symptoms such as dyspnea and fatigue.
- Trial name
- NCT05708443
- Testing
- LL group, L+UL group
- Where
- 3 sites in Italy
- Volunteers
- 36 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
COPD (Chronic Obstructive Pulmonary Disease), COPD
Dupilumab in Type 2-Inflamed COPD Across the Full Spectrum of Airflow Limitation: An Italian Multicentre Retrospective Cohort Study
This multicentre retrospective cohort study describes lung function and patient-reported outcomes in adults with chronic obstructive pulmonary disease (COPD) and type 2 inflammation who received add-on dupilumab in routine…
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD, Eosinophilia
- Trial name
- DUPICENTRO (NCT07788092)
- Testing
- Dupilumab
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera di Perugia
Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
Towards Personalized Nutrition With SCAPIS2-HOME
The Swedish CardioPulmonary bioImage Study (SCAPIS) is a nationwide, open-access, population-based cohort in Sweden designed to study cardiovascular disease and chronic obstructive pulmonary disease.
- Trial name
- NCT06992921
- Testing
- Dietary intervention
- Where
- 2 sites in Sweden
- Volunteers
- 1,641 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Asthma, COPD
An Open Study to Assess the Robustness of the CRC749 Inhaler
To confirm the robustness of the CRC749 inhaler.
- Trial name
- NCT02474017
- Testing
- MGR001, CRC749 inhaler
- Where
- 2 sites in United Kingdom
- Volunteers
- 111 people
- Sponsor
- Mylan Pharma UK Ltd.
Asthma, Lung Diseases, Obstructive
Statistical Analysis of Vlagtwedde-Vlaardingen Data Set
To determine the effects in early adulthood of asthma, increased bronchial responsiveness, markers of allergy and smoking on pulmonary function level and the effects of these same risk factors on subsequent decline in pulmonary…
- Conditions
- Asthma, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005425
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Obstructive Pulmonary Disease
Home Mechanical Ventilation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypercapnic Response
The objective of this study is to evaluate the clinical benefits of home mechanical ventilation associated to oxygen therapy in COPD patients with chronic respiratory failure (CRF) who develop hypercapnia and nocturnal…
- Trial name
- NCT01120574
- Testing
- Home mechanical ventilation
- Where
- Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Chronic Obstructive Pulmonary Disease
Long-term Impact of Pulmonary Rehabilitation
This study has been designed to capture a large group of patients who undergo pulmonary rehabilitation and map their progression over a 5 year time-frame.
- Trial name
- NCT00959855
- Testing
- Pulmonary Rehabilitation
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Beaumont Hospital
Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
Effect of Maternal Smoking On Neonatal Lung Function
To determine factors, including maternal cigarette smoking and acute respiratory illness, influencing infant lung function at birth and up to five years of age.
- Trial name
- NCT00005285
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma (Part 1), COPD
APP-based Medical Device for Education and Training of Inhalation Technique
Primary aim: To investigate if app-based education and training of inhalation technique improves the rate of successful inhalation techniques compared with control group at 6-12 weeks follow-up visit.
- Trial name
- APPETITE (NCT07145632)
- Testing
- App-based education and training of inhalation technique
- Where
- 3 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Copd, COVID-19
Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19
The purpose of this research project is to study small airways physiological function in patients with chronic obstructive lung disease or COVID-19 and explore the relationship with in-vivo microanatomical small airway structure…
- Conditions
- Copd, COVID-19, Asthma, Small Airways Disease
- Trial name
- PASSPORT (NCT04716023)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease
Balance Training for Chronic Obstructive Pulmonary Disease (COPD)
The study will involve direct knowledge translation of a laboratory-based study of balance training for patients with COPD, first to the investigators PR program and then, after disseminating the results, this approach could be…
- Trial name
- NCT02080442
- Testing
- Balance training
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Samantha Harrison
Lung Cancer, Precancerous Condition
Screening for Lung Cancer in Current or Past Smokers With Chronic Obstructive Pulmonary Disease
RATIONALE: Screening tests or exams may help doctors find lung cancer sooner, when it may be easier to treat. PURPOSE: This randomized clinical trial is studying screening tests or exams to see how well they work compared to…
- Trial name
- NCT00512746
- Testing
- cytology and cytometry specimen collection procedure, Chest x ray, Autofluorescence bronchoscopy
- Where
- 10 sites in United Kingdom
- Volunteers
- 1,569 people
- Sponsor
- University College, London
Chronic Obstructive Pulmonary Disease (COPD)
Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) affects at least 750,000 Canadians and is currently the 4th leading cause of death in Canada.
- Trial name
- ROS-003 (NCT00982891)
- Testing
- Opioid (morphine sulphate) in low dose
- Where
- 3 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Nova Scotia Health Authority
Pulmonary Disease, Chronic Obstructive, Rehabilitation
A Trial to Study the Effects of Pulmonary Rehabilitation Program on Exercise Capacity and Quality of Life in Patients With Severe Form of Chronic Obstructive Pulmonary Disease (COPD)
This study is a randomized parallel group controlled trial which aims to study the effects of pulmonary rehabilitation intervention on exercise capacity and quality of life in patients with severe COPD as compared to standard…
- Trial name
- RehabCOPD (NCT02512549)
- Testing
- Pulmonary Rehabilitation
- Where
- India
- Volunteers
- 80 people
- Sponsor
- All India Institute of Medical Sciences
Chronic Obstructive Pulmonary Disease (COPD)
Feasibility Study of Telerehabilitation for People with Chronic Obstructive Pulmonary Disease in Nuuk
Chronic obstructive pulmonary disease, or COPD, is a major global health issue. It can make people ill, impact their quality of life, and increase their use of healthcare services.
- Trial name
- NCT06660589
- Volunteers
- 10 people
- Sponsor
- Steno Diabetes Center Greenland
Asthma, Lung Diseases, Obstructive
Genetics of Airway Responsiveness and Lung Function
To perform a genome-wide search for genes affecting two phenotypes related to asthma and chronic obstructive pulmonary disease (COPD) in a Chinese population.
- Conditions
- Asthma, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005537
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pulmonary Disease, Chronic Obstructive
Changes in Blood Gases, Disturbance of Breath During Sleep and Cardiovascular Co-morbidity in COPD Patients
Respiration failure type 2 is loss of the lungs ability to take up oxygen (O2) and get rid of carbon dioxide (CO2). The diagnosis is based on blood gas measurement of pressures of O2 and CO2.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxemia
- Trial name
- NCT00888342
- Testing
- supplementary oxygen, zopiclone, alcohol
- Where
- 2 sites in Norway
- Volunteers
- 150 people
- Sponsor
- LHL Helse
Severe COPD
The Identification of Phenotypes in Patients With Severe Chronic Obstructive Pulmonary Disease (Groningen Severe COPD Cohort)
Rationale: Chronic Obstructive Pulmonary Disease (COPD) is defined by airway obstruction. However, the degree of airflow limitation does not adequately describe the complexity of COPD because significant heterogeneity exists…
- Trial name
- NCT04023409
- Testing
- NA: no intervention
- Volunteers
- 1,030 people
- Sponsor
- University Medical Center Groningen