Clinical trials: Cannabis Use Disorder
Cancer, Epilepsy
Real World Evidence on the Use of Medical Cannabis in Pediatrics
CAN-RWE is an observational study that is following 500 children who have authorizations for medical cannabis for two years from across Canada.
- Conditions
- Cancer, Epilepsy, Neurodevelopmental Disorders
- Trial name
- CAN-RWE (NCT05863910)
- Testing
- Medical Cannabis
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Manitoba
Cannabis
Internet-Based Treatment for Individuals With Regular Cannabis Use: A Randomized Controlled Trial
The aim of this randomized controlled trial is to investigate the effects of a Swedish Internet-based treatment program for individuals from the general population with a regular cannabis use.
- Trial name
- NCT02408640
- Testing
- Cannabishjalpen.se
- Where
- Sweden
- Volunteers
- 303 people
- Sponsor
- Karolinska Institutet
Marijuana Use
Project Chill: Tailored Youth Drug Intervention In Primary Care
This study examines the impact of tailored computer-delivered and therapist-delivered brief motivations prevention/interventions both for adolescents who have not initiated marijuana use (prevention), and those who use marijuana…
- Trial name
- NCT01329315
- Testing
- BMI-T, BMI-C
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Vaping, Adolescent
Nicotine and Cannabis Vape Labeling Experiment - Spring 2025
This study assesses how the ways in which nicotine and cannabis vaping devices are labeled impact use susceptibility, anticipated effects, and health harm.
- Conditions
- Vaping, Adolescent, Electronic Cigarette Use, Nicotine
- Trial name
- EPIC/ADVANCE (NCT06919276)
- Testing
- Vaping Device Labeling
- Where
- United States
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Psychotic Disorders, Psychiatric Hospitalization
Youth Experiences and Health Study
This study aims to identify unusual experiences and psychiatric symptoms that indicate a heightened risk for severe mental disorders - especially psychoses.
- Conditions
- Psychotic Disorders, Psychiatric Hospitalization, Prodromal Symptoms, Cannabis Use
- Trial name
- YEAH (NCT03332966)
- Testing
- Psychiatric questionnaires, Semi-structured psychiatric interview
- Where
- 3 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Finnish Institute for Health and Welfare
Cannabis Use, Marijuana Use
Cannabis Use in Pregnancy and Downstream Effects on Maternal and Infant Health
With perinatal cannabis use rising in Canada, robust data on short-term and long-term effects on newborns are urgently needed. However, past barriers to obtain robust data included limited sample sizes, low self-reporting and no…
- Trial name
- CUPiD (NCT05309226)
- Testing
- Cannabis use in pregnancy or cannabis exposure in utero
- Where
- 4 sites in Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Tobacco Use, Substance Use
Tobacco-Concurrent Addictions in At-Risk Youth in Ottawa
According to the 2015 Ontario Student Drug Use and Health Survey (OSDUHS), there has been a significant increase in the number of secondary school youth who use poly-substances.
- Conditions
- Tobacco Use, Substance Use, Cannabis Use
- Trial name
- TCAY-Ottawa (NCT04812613)
- Where
- Canada
- Volunteers
- 520 people
- Sponsor
- Ottawa Hospital Research Institute
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Substance Use, Substance-Related Disorders
Clinician Practice Companion to Address Youth Substance Use
Substance use, including the use of opioids, cannabis, and other drugs, is common among adolescents and young adults, and overdose has become a leading cause of death among youth in Canada and the United States.
- Conditions
- Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use
- Trial name
- NCT07725289
- Testing
- Practice Companion
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Cannabis Use Disorder, Depressive State
Substance Misuse To Psychiatric Disorders for Cannabis
With the recent availability of vortioxetine, and the surging phenomenon of cannabis misuses amongst young abusers, it is a timely opportunity to conduct an early pharmacotherapy intervention study to offer an evidence-based…
- Conditions
- Cannabis Use Disorder, Depressive State, Anxiety State, Depression
- Trial name
- NCT03485274
- Testing
- Vortioxetine, Treatment as Usual
- Where
- Hong Kong
- Volunteers
- 37 people
- Sponsor
- The University of Hong Kong
Mental Illness, Schizophrenia
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Severe mental illness (SMI) refers to the most burdensome psychiatric conditions. The need to pre-empt the onset of SMI is pressing because once SMI develops, quality of life is poor and available treatments have limited…
- Conditions
- Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- IMAGINE (NCT03601026)
- Testing
- Genetic counselling
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Cannabis-Related Disorder, Substance-Related Disorders
First Episode Schizophrenia and Cannabis-Related Disorder Study
Many individuals with schizophrenia abuse cannabis at the onset of their illness, portending a poorer course of illness and poorer treatment response.
- Conditions
- Cannabis-Related Disorder, Substance-Related Disorders, Schizophrenia, Psychotic Disorders
- Trial name
- NCT00573287
- Testing
- clozapine, risperidone
- Where
- 5 sites in United States
- Volunteers
- 14 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Cannabis Use Disorder
Teen Marijuana Check-Up
This study will test a behavioral intervention tailored for adolescents who smoke marijuana and have concerns about their use. The study's purpose is to determine whether this intervention (two-sessions of motivational…
- Trial name
- NCT01109563
- Testing
- Marijuana Check-Ins
- Volunteers
- 252 people
- Sponsor
- Denise Walker
Adolescent Drinking, Adolescent Problem Behavior
Mindfulness Mobile App to Reduce Adolescent Substance Use
Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal…
- Trial name
- Qlarity (NCT04027075)
- Testing
- Qlarity app users
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Marijuana Use, Alcohol Consumption
A Clinical Trial of SBIRT Services in School-based Health Centers
The purpose of the study is to examine the comparative effectiveness of a computerized brief intervention vs. an in-person brief intervention delivered by a nurse in reducing marijuana, alcohol, and sex risk behaviors in…
- Conditions
- Marijuana Use, Alcohol Consumption, Unsafe Sex, Risk Behavior
- Trial name
- NCT02387489
- Testing
- Brief in-person motivational intervention, Computerized Brief Intervention
- Volunteers
- 300 people
- Sponsor
- Friends Research Institute, Inc.
Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Bupropion for ADHD in Adolescents With Substance Use Disorder
Attention deficit hyperactivity disorder (ADHD) is one of the most common co-occurring psychiatric disorders (30-50%) in adolescents with substance use disorders (SUD).
- Conditions
- Attention Deficit Hyperactivity Disorder, Nicotine Dependence, Cannabis Use Disorder
- Trial name
- NCT00936299
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Colorado, Denver
Cannabis Use
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder
This project seeks to learn more about the effects of cannabis use on the endocannabinoid system and endogenous opioid systems in adolescents to address a fundamental gap in knowledge and identify biomarkers that may help…
- Trial name
- NCT05396638
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Cannabis Use
A Hybrid Effectiveness-Implementation Trial of a School-Based Teen Marijuana Checkup
A hybrid effectiveness-implementation trial that is designed to assess the effectiveness of an intervention (The Teen Marijuana Check-Up) when delivered in real world settings.
- Trial name
- TMCU5 (NCT03111667)
- Testing
- Teen Marijuana Check Up, Treatment as Usual, Gold Standard Coaching
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Washington