Clinical trials: Cardiac Conduction Defect
Ventricular Fibrillation, Ventricular Tachycardia
Implantable Cardioverter Defibrillator (ICD) Support Groups and Veterans
In this study, we will compare the quality of life in veterans having ICD who attend the ICD support groups to those who do not.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Sudden Cardiac Death
- Trial name
- NCT00846417
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Emory University
Supraventricular Tachycardia
Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)
The goal of this study is twofold. First the investigators would like to determine the trajectory of troponin leaks; if it can be shown that the participants who have only minimal elevations of their repeat troponin universally…
- Trial name
- NCT02810561
- Testing
- No Intervention
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Sudden Cardiac Death, Sudden Cardiac Arrest
Low QRS Voltages in Young Healthy Individuals and Athletes
There is some limited evidence that reduced size of electrical complexes/traces of the heart on the electrocardiogram (ECG) may be associated with scarring in the heart muscle, which may predispose to serious life-threatening…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Sudden Cardiac Death Due to Cardiac Arrhythmia, Arrhythmogenic Right Ventricular Cardiomyopathy
- Trial name
- NCT05799833
- Testing
- Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Brugada Syndrome
European Perioperative Brugada Survey
The aim of this survey is to assess the current perception and clinical practice of Resident and Board-certified Anaesthesiologists and Intensivists regarding perioperative care of patients burdened with the Brugada Syndrome.
- Trial name
- NCT04808193
- Testing
- Survey
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Brugada Syndrome
Southeast Asian Brugada Syndrome Cohort
Brugada syndrome (BrS) is the leading cause of sudden death in young Asian adults including Thailand. This syndrome may be hereditary and involve mutations in certain genes.
- Trial name
- SEA-BrS (NCT04232787)
- Where
- 11 sites in Thailand
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Premature Ventricular Contractions
Concealed Myocardial Abnormalities by Cardiac Magnetic Resonance Imaging in Idiopathic VT
Idiopathic Ventricular arrhythmia (VAs) refers to VAs that occur in the absence of clinically apparent structural heart disease.
- Trial name
- NCT06146556
- Testing
- catheter based ablation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiac; Dysrhythmia, Postoperative, Congenital Heart Surgery
Prevention of Post-Operative Cardiac Arrhythmias
Aim 1: Primary Prevention of Post-operative Cardiac Arrhythmias 1. To evaluate the efficacy of dexmedetomidine vs. the combination of Magnesium Sulfate and dexmedetomidine for the prevention of post-operative cardiac arrhythmias…
- Trial name
- POCA (NCT04234906)
- Testing
- Dexmedetomidine, Magnesium Sulfate, Amiodarone
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Jeffrey Moak
Sudden Unexplained Death Syndrome, Sudden Unexplained Death in Childhood
Sudden Unexplained Death in Childhood (SUDC) Registry
The purpose is to increase the understanding of the characteristics, circumstances, medical histories and pathologies of children from ages 11 months through 18 years who have died suddenly and unexpectedly, and in some…
- Trial name
- SUDC (NCT03109197)
- Testing
- Biospecimin Collection
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sensorineural Hearing Loss, Long QT Syndrome
Determine the Incidence of Long QT Amongst a Large Cohort of Subjects Diagnosed With Unilateral or Bilateral Sensorineural Hearing Loss.
The purpose of this study is to determine the true incidence of long QT (LQT) amongst a large cohort of subjects diagnosed with unilateral (right/left) or bilateral sensorineural hearing loss.
- Trial name
- NCT02082431
- Where
- 12 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Congenital Complete Heart Block, Cardiac Conduction Defect Progressive
Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms
Identification of genes involved in congenital atrioventricular block and progressive Cardiac Conduction Disease.
- Trial name
- NCT02881671
- Testing
- genetic blood analysis
- Where
- 2 sites in France
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Long QT Syndrome
KCNQ1 Cascade Screening
The objectives of the protocol are to: (1) evaluate the uptake of cascade screening and preventative therapies after the implementation of a simplified screening process and (2) assess proband and family member perspectives about…
- Trial name
- NCT03783975
- Testing
- Simplified Cascade Screening
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Ventricular Tachycardia
Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)
Medtronic is sponsoring the Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) to further confirm safety and effectiveness of ventricular iATP therapy in routine clinical practice, following commercial release of…
- Trial name
- NCT04496518
- Testing
- Intrinsic Antitachycardia Pacing (iATP) Therapy
- Where
- 92 sites in United States, France and 7 more
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Medtronic
Heart Rate Fast, Blood Pressure
Short-term Effects of Passiflora and Meditation on Blood Pressure and Heart Rate
This study is intended to study the effects of one-time acute dosing of a solid extract of Passiflora incarnata, also known as Passionflower, on blood pressure and heart rate in students.
- Trial name
- NCT03953469
- Testing
- Passiflora incarnata
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Bridgeport
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Long QT Syndrome, Hypoglycemia
Frequency of Hypoglycemia in Children With Beta-blocker Treated Long QT-syndrome
The goal of this observational study is to investigate the frequency and characteristics of hypoglycemic episodes in children with long QT syndrome (LQTS) and beta-blocker treatment, specifically those receiving propranolol…
- Trial name
- LQThypo (NCT07233421)
- Testing
- Continuous Glucose Monitoring
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies
Mayo AVC Registry and Biobank
Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT03049254
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bundle-Branch Block, Heart Septal Defects, Ventricular
Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
The most common congenital heart disease is the ventricular septal defect, and after surgical closure of a such defect, an arrythmia called the right bundle branch block, is very frequent.
- Trial name
- NCT01480908
- Testing
- Echocardiography at rest, Echocardiography during exercise, MRI at rest
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sick Sinus Syndrome
The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome
Evidence has been documented for the close relationship between the arrhythmia pathogenesis and the gene expression in renin-angiotensin system.
- Trial name
- NCT01310920
- Testing
- observation
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Long QT Syndrome
Long QT Syndrome Screening in Newborns
The purpose of this project is to test a new, very compact, 12-lead ECG device as a way to detect long QT syndrome (LQTS) in infants. The device -- called QTScreen -- was developed in Phase I of this project.
- Trial name
- NCT02412709
- Testing
- QTScreen ECG Recorder
- Where
- 3 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- QT Medical, Inc.
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International