Clinical trials: Cardiac Output Measurement
Critical Illness, Pediatrics
Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO
The purpose of this study is to compare the accuracy and precision of two non-invasive methods of measuring cardiac output in critically ill children (<18 yrs).
- Trial name
- NCT01460329
- Testing
- Ultrasonic Cardiac Output Monitor (USCOM).
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of North Carolina, Chapel Hill
Fluid Responsiveness, Cardiac Output
Echocardiography in Kids Intensive Care Decision Support
A study to determine if echocardiographically derived parameters, plethysmographic variability index and pulse pressure variation predict fluid responsiveness in children on PICU.
- Trial name
- ECHOKIDS (NCT01821742)
- Testing
- Ultrasound cardiac output measurement
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Congenital Heart Disease
Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD
This study will test the capability of a non-invasive instrument (the PhysioFlow impedance cardiography instrument) to measure cardiac output in patients with congenital heart disease (CHD).
- Trial name
- NCT02326649
- Testing
- Physioflow
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, San Diego
Hemodynamically Stable, Critical Illness
Comparing USCOM and Echocardiographic Hemodynamic Measurements in Children (CUE Study)
The primary objective of this study is to evaluate the agreement between hemodynamic measurements obtained using the Ultrasound Cardiac Output Monitor (USCOM®; USCOM Ltd., Sydney, Australia), and reference standards as determined…
- Trial name
- NCT02083172
- Testing
- Ultrasound Cardiac Output Monitor and 2 D-Echo
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- McMaster University
Sepsis
Non-invasive Measurement of CO in Patients With Uncomplicated Sepsis
Little is known about the optimal fluid therapy of patients with uncomplicated sepsis. Most recommendations are extrapolated from studies performed in patients with septic shock.
- Trial name
- NCT03728998
- Testing
- Passive leg raise (PLR), Clearsight non-invasive hemodynamic monitoring system
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Frisius Medisch Centrum
Cardiac Output
Accurate Measurement of Cardiac Output Using the Ultrasound Dilution Technique
Accurate cardiac output determination is a commonly used and important index of myocardial performance. The thermodilution method using a pulmonary artery catheter is the most common approach to cardiac output determination…
- Trial name
- BCM (NCT00851422)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Transonic Systems Inc.
Perfusion Pressures, Central Venous Pressure
Sternal Wall Pressure in the Cath Lab
This protocol is a prospective interventional pilot study at the Children's Hospital of Philadelphia to determine whether or not two increments of sternal pressure known to occur during "leaning" in CPR affects hemodynamic…
- Conditions
- Perfusion Pressures, Central Venous Pressure, Cardiac Output, CPR
- Trial name
- NCT01117883
- Testing
- Application of two different sternal weights
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Shock, Hypotension and Shock
ClearSight Validation in Pediatrics
Specific aim 1: The specific aim of this study is to compare cardiac output measurements as well as cardiac index, and stroke volume obtained via thermodilution during a cardiac catheterization with data obtained by the…
- Trial name
- NCT03701646
- Testing
- Measurement by Clearsight device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Congenital Heart Disease
Impedance During Cardiac Catheterization to Build a Non-Invasive Cardiac Output Algorithm
Prospectively measure impedance during cardiac catheterization to build a cardiac output algorithm.
- Trial name
- NCT06171698
- Testing
- Research Prototype Monitor
- Where
- United States
- Sponsor
- Johns Hopkins University
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Intensive Care
Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)
Assessment and monitoring of cardiac function in the pediatric intensive care unit (PICU) is an integral part of hemodynamic monitoring of critically ill patients whether it is done directly or indirectly.
- Trial name
- NCT01613859
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Transonic Systems Inc.
Pregnancy Related, Cardiac Output
Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques
the goal of this clinical trial is to compare the measurement of cardiac output, systolic ejection volume and vascular filling in pregnant women with the new non-invasive measurement techniques of the Index of contractility…
- Trial name
- NCT06114147
- Testing
- trans thoracic echocardiography measure, ICON measure, USCOM
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Intensive Care Units, Pediatric
Cardiac Output Measurement in Pediatric Intensive Care Unit by Metabolic Monitor (Fick Method) (PEDIA-FICK-ICU)
Cardiac output measurement is one of the most frequently used haemodynamic parameter used for intensive care unit (ICU) patients.
- Trial name
- PEDIA-FICK-ICU (NCT05741918)
- Testing
- Fick's method, Echocardiography
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Recirculation, Oxygenator Blood Volume
Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation
This study is to test the usefulness of ultrasound dilution measurements in patients on extracorporeal membrane oxygenation. Measurements may include; efficiency of support (recirculation), amount of clotting in the oxygenator…
- Conditions
- Recirculation, Oxygenator Blood Volume, Cardiac Output, Venoarterial Extracorporeal Membrane Oxygenation
- Trial name
- NCT00920569
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Transonic Systems Inc.
Cardiac Output
Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients
The ability to measure cardiac output (CO) accurately and reproducibly at frequent intervals remains elusive to the clinician caring for critically ill pediatric patients even though a large proportion of these children are known…
- Trial name
- GCH (NCT00853437)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Transonic Systems Inc.
Cardiac Output
Cardiac Output Measurement at the Conclusion of Cardiopulmonary Bypass
Cardiac output, the amount of blood pumped by the heart in one minute, will be measured in pediatric patients undergoing surgery involving cardiopulmonary bypass (CPB).
- Trial name
- NCT01103908
- Testing
- HCE101 Cardiopulmonary Support Monitor
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Transonic Systems Inc.
Pediatric Disorders
PHYSIOFLOW/Comparison of Cardiac Output Measurement
PhysioFlow® (PF®) is a new cardiac output (CO) monitoring method by impedance cardiography (IC), never studied in pediatric intensive care unit (PICU).
- Trial name
- PF-ECHO (NCT02873494)
- Testing
- PHYSIOFLOW - PF05 Lab1TM
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Lille
Post Cardiac Surgery
Measure Cardiac Output Using Ultrasound Dilution in Mechanically Ventilated Children
The measurement of cardiac output (CO) and hemodynamic pressures are vital for proper management of severely hemodynamic compromised patients.
- Trial name
- NCT01662141
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Transonic Systems Inc.
Pre-Term, Neonatal Infection
Non-invasive Measurement of Neonatal Central and Peripheral Hemodynamics
Non-invasively neonatal cardiac output can be measured by multiple methods, but the gold standard still remains conventional echocardiography. It is accurate, but needs a long training for new users to assess cardiac function.
- Trial name
- NInHeDyNeo (NCT04200807)
- Testing
- Ultrasound Cardiac Output Monitor (USCOM 1A)
- Where
- Lithuania
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Vilnius University