Clinical trials: Cardiovascular Adaption
Post Stroke Aphasia
Adaptation of Melodic Intonation Therapy to Spanish
This study was conducted in three phases: The first phase involved creation of a Spanish adaptation of the Melodic Intonation therapy; the second phase consisted of a pilot non-randomized intervention study to analyse its…
- Trial name
- NCT03433495
- Testing
- Melodic Intonation Therapy
- Volunteers
- 20 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pseudoxanthoma Elasticum
Impact of Optimized Recruitment and Follow-up of Patients With Pseudoxanthoma Elasticum (PXE)
Pseudoxanthoma elasticum (PXE) is a rare genetic disorder characterized by ectopic calcifications in the skin, retina and arterial walls. Angers University Hospital is the national rare disease reference center (CRMR) for PXE.
- Trial name
- REMOTE-PXE (NCT06636344)
- Testing
- Pseudoxanthoma Elasticum
- Where
- France
- Volunteers
- 650 people
- Sponsor
- University Hospital, Angers
Transgender
Body Composition Assessment in Transgender Population.
Gender-affirming hormone therapy (GAHT) is a fundamental component of medical transition in transgender men, promoting body composition changes that align physical characteristics with gender identity and alleviate gender…
- Trial name
- BIVATRANS (NCT07481942)
- Testing
- gender affirming hormone therapy
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Celia Bañuls
Right Ventricular Hypertrophy, d-TGA
Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) Findings
Systemic RV hypertrophy and impaired systolic function occur after atrial switch (AS) in d-transposition of the great arteries (d-TGA). Echocardiography has limitation in the assessment of the right ventricle (RV).
- Trial name
- NCT01430897
- Where
- Germany
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Spatial Neglect
Engaging Mobile Prism Adaptation Treatment at Home
Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space.
- Trial name
- EMPATH (NCT05595668)
- Testing
- Prism Adaptation - 15-degree prism goggles, Prism Adaptation - 5-degree prism goggles
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Circulatory Failure in Newborn Infants
NeoAdapt 1: A Study of Circulatory Adaptation of Newborn Infants After Birth
The current definitions of neonatal shock/circulatory failure are outdated and inaccurate. This makes the development of evidence based protocols for its treatment very difficult.
- Trial name
- NCT02047916
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Pregnancy
Echo-Cardiographic Assessment of Cardiovascular Characteristics During Pregnancy and Postpartum Periods
The purpose of this echocardiographic study is to restudy the longitudinal changes in cardiac size and function during and after pregnancy in healthy women using relatively new parameters of systolic and diastolic function as…
- Trial name
- NCT00522977
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Pregnancy Related, Physical Activity
The Effects of Aerobic Water Exercise on Pregnancy
Objective: To assess the relationship between maternal cardiovascular capacity and aerobic water exercise during the gestational periods of hemodynamic overload.
- Trial name
- NCT01364506
- Testing
- Water aerobic exercise
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Asthma, Cardiovascular Diseases
Trial to Enhance Adherence to Multiple Guidelines
To evaluate whether the innovative multimethod assessment process/participatory quality improvement (MAP/PQI) intervention increases adherence to multiple cardiorespiratory guidelines in primary care practice.
- Conditions
- Asthma, Cardiovascular Diseases, Atherosclerosis, Diabetes Mellitus
- Trial name
- ULTRA (NCT00201227)
- Testing
- practice guideline adherence
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Heart Failure
Urdu Translation and Validation of MLHFQ
To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan. To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire…
- Trial name
- NCT06076447
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- Riphah International University
Hypertension
APROVE : Irbesartan in Hypertension
Study objective : To compare efficacy and tolerability of posology adaptation of Irbesartan in ambulatory Hypertensive patients
- Trial name
- NCT00283036
- Testing
- Irbesartan
- Where
- Algeria
- Volunteers
- 200 people
- Sponsor
- Sanofi
Brain Damage
Cross-cultural Adaptation to the Spanish Population and Validation of the BESTest and Mini-BESTest
Due to brain damage acquired (BDA), is often difficulty in gait and balance alterations, as problems that patients designated as the most disabling. It is essential to an effective assessment of the balance.
- Trial name
- BESTest (NCT04052087)
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Centro de Referencia Estatal de Atención Al Daño Cerebral
Acute Coronary Syndromes
Myocardial Infarction
The effect of nursing approach based on Meleis's transition theory on cardiac quality of life and adaptation to disease in patients with acute myocardial infarction.
- Trial name
- Nursing Theory (NCT06948123)
- Testing
- Educational intervention, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Aydin Adnan Menderes University
Cardiovascular Fitness
SAQ Training Versus Small-Sided Games for Cardiovascular Adaptations in Youth Football Players
This randomized controlled trial aimed to compare the effects of Speed, Agility, and Quickness (SAQ) training and Small-Sided Games (SSGs) on cardiovascular adaptations in youth football players.
- Trial name
- SAQ-SSG (NCT07633210)
- Testing
- SAQ Training, Small-Sided Games Training
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Benha University
Marfan Syndrome
Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome
This research study aims to evaluate the effect of a 6-month adapted physical activity program (APA) on the endurance capacities (evaluated as the maximum oxygen consumption [VO2 peak] on a cardiopulmonary exercise test) of…
- Trial name
- M&M's (NCT05838235)
- Testing
- Adapted Physical Activity program
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Multiple Myeloma
Risk-adapted Therapeutic Strategy in +1q NDMM
This real-world, multicenter prospective clinical study is designed to apply our internationally developed prognostic scoring system to guide individualized therapy in +1q newly diagnosed multiple myeloma (NDMM), using minimal…
- Trial name
- NCT07045168
- Testing
- risk-scoring model
- Where
- China
- Volunteers
- 200 people
- Sponsor
- FengYan Jin
Gene Mutations, Pseudoxanthoma Elasticum
ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency
The purpose of this study (Study INZ701-304 [ADAPT]) is to assess the long-term safety of INZ-701 in patients with ENPP1 Deficiency or ABCC6 Deficiency who have received INZ-701 in an existing clinical study and choose to…
- Conditions
- Gene Mutations, Pseudoxanthoma Elasticum, Arterial Calcification, Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency
- Trial name
- NCT06462547
- Testing
- INZ-701
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 22 people
- Sponsor
- Inozyme Pharma
Lipoproteinemia, Apheresis Related Complication
Long-term Characterization of Lipoprotein Apheresis Technologies for Individual Device Adaption (LOLIDA)
Lipoprotein apheresis is often applied as the final treatment of patient with severe and medication resistant dyslipidemia and progressive atherosclerosis.
- Conditions
- Lipoproteinemia, Apheresis Related Complication, Cardiovascular Diseases
- Trial name
- LOLIDA (NCT05181969)
- Testing
- Dextran sulfate absorption (LIPOSORBER® D - Kaneka Pharma Europe NV), Lipid filtration (Octo Nova®, Diamed Medizintechnik), Direct absorption of lipoproteins (DALI®; ADS 4008, Fresenius)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Technische Universität Dresden
Congenital Heart Disease, Postoperative Care
Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach
The purpose of this clinical trial is to learn about the effects of a nursing support program designed for families of children aged 1 to 3 years who have undergone heart surgery.
- Conditions
- Congenital Heart Disease, Postoperative Care, Child Development, Roy Adaptation Model-based Nursing Empowerment Program
- Trial name
- NCT07575451
- Testing
- RAM-based Nursing Empowerment Program, Routine Care and Educational Booklet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine