Clinical trials: Cardioversion
Out of Hospital Cardiac Arrest
Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation
The hypothesis of this study is Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NAD-CPR) would improve survival of out-of-hospital cardiac arrest (OHCA).
- Trial name
- NCT02010151
- Testing
- NAD-CPR
- Where
- South Korea
- Volunteers
- 3,194 people
- Sponsor
- Seoul National University Hospital
Tachyarrhythmia
Lead Evaluation for Defibrillation and Reliability Post Approval Study
Medtronic is sponsoring the LEADR PAS to provide continuing evaluation and periodic reporting of safety and effectiveness of the OmniaSecure™ defibrillation lead following commercial release.
- Trial name
- LEADR PAS (NCT07005232)
- Testing
- defibrillation lead
- Where
- 73 sites in United States, Austria and 5 more
- Volunteers
- 2,000 people
- Sponsor
- Medtronic
Cardiorespiratory Arrest
Impact of Realistic Simulation Training on Nurses' Cardiopulmonary Resuscitation Performance
Introduction: Cardiopulmonary arrest is one of the most prevalent cardiovascular emergencies worldwide, associated with high morbidity and mortality.
- Trial name
- SIM-CPR Nurses (NCT07623447)
- Testing
- CPR training for nurses with the use of electrical therapy
- Where
- Brazil
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Primary Prevention of Sudden Cardiac Arrest, Secondary Prevention of Sudden Cardiac Arrest
Longitudinal Surveillance Study of the 4-SITE Lead/Header System
Post-approval studies of implanted leads provide an opportunity to observe and assess patient outcomes and technology performance in a real-world setting.
- Trial name
- LSS of 4-SITE (NCT01596595)
- Where
- 111 sites in United States, Australia and 1 more
- Volunteers
- 1,820 people
- Sponsor
- Boston Scientific Corporation
Emergency Department Procedural Sedation, Fracture Reduction
Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia
When patients come to the Emergency Department with injuries and infections they often need to have painful procedures performed that are essential to allowing them to recover.
- Conditions
- Emergency Department Procedural Sedation, Fracture Reduction, Abscess Incision and Drainage, Electrical Cardioversion
- Trial name
- NCT01211158
- Testing
- Ketofol, Propofol alone
- Where
- Canada
- Volunteers
- 284 people
- Sponsor
- Lions Gate Hospital
Tachyarrhythmia
Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)
The LEADR study is designed to assess the safety and efficacy of the Next Generation ICD lead. The LEADR LBBAP study is being conducted under the existing US FDA Investigational Device Exemption (IDE) for the Next Generation ICD…
- Trial name
- NCT04863664
- Testing
- Defibrillation (RV Implant), Defibrillation (LBBAP Implant)
- Where
- 55 sites in United States, Australia and 18 more
- Volunteers
- 998 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Ventricular Fibrillation, Cardiac Arrest
SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular…
- Trial name
- SmartCPR (NCT00535106)
- Testing
- Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 900 people
- Sponsor
- New York City Fire Department
Atrial Fibrillation
Study of Normal Conditions of Use, Dosing, and Safety of Intravenous (IV) Administration of Vernakalant (MK-6621-049)
This non-interventional prospective study is a post-authorization safety study (PASS) of vernakalant conducted to collect information about normal conditions of use and appropriate dosing, and to quantify possible medically…
- Trial name
- NCT01370629
- Testing
- Vernakalant
- Where
- 6 sites in Austria, Denmark and 4 more
- Volunteers
- 2,015 people
- Sponsor
- Correvio International Sarl
Cardiac Arrest
Improving Defibrillation Pad Position
Manufacturer's diagrams showing defibrillation pad positioning (as used on public access defibrillators) are anatomically incorrect and are likely to lead to poor position of defibrillation pads, with reduced defibrillation…
- Trial name
- NCT03476720
- Testing
- Pad positioning according to a manufacturer's diagram
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Erectile Dysfunction
Evaluation for Restoration of Erectile Dysfunction After Cardioversion Treatment Trial
Erectile and Cognitive function by using the questionnaire and assessment form before sinus conversion
- Trial name
- NCT02742896
- Testing
- Erectile dysfunction
- Where
- South Korea
- Sponsor
- Yong Seog Oh
Pediatrics, Defibrillators, Implantable
Precise Measurement of Pediatric Defibrillation Thresholds
Patients who receive an implantable cardioverter-defibrillator (ICD) usually undergo testing at the end of the ICD procedure to measure the amount of energy able to successfully defibrillate the heart (defibrillation threshold…
- Trial name
- NCT01043562
- Testing
- Defibrillator threshold testing, Observation of post-shock intrinsic cardiac rhythm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Boston Children's Hospital
Atrial Fibrillation Fluttering
Ankle - Brachial Index Measurement in Atrial Fibrillation
Consecutive patients with atrial fibrillation will be admitted to the hospital for electrical cardioversion. Ankle brachial index will be measured three times with oscillometric method and three times with doppler method.
- Trial name
- AFABI (NCT02986282)
- Testing
- ABI measurement using both doppler and oscillometric method
- Volunteers
- 115 people
- Sponsor
- Medical University of Warsaw
Cardiac Arrest, Sudden, Ventricular Tachycardia
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer…
- Conditions
- Cardiac Arrest, Sudden, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- DEFI-2022 (NCT04691089)
- Where
- France
- Volunteers
- 285 people
- Sponsor
- French Defence Health Service
Left Atrial Appendage Thrombi
Detection of Left Atrial Appendage (LAA) Thrombus: Comparison of Cardiac Magnetic Resonance Imaging and Transesophageal Echocardiogram
The purpose of this study is to compare Cardiac Magnetic Resonance (CMR) Imaging with transesophageal echocardiography (TEE) in detecting the presence of LAA thrombi in men and women with atrial fibrillation presenting for…
- Trial name
- NCT00797576
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation
Cardiac Arrest, Identify of Electrocadiac Rhythm
Identification of Ventricular Fibrillation and Optimization of Defibrillation During CPR
It's so important to recognize ventricular fibrillation in cardiac arrest and defibrillation early. At the same time Research findings have identified high-quality CPR with minimum interruption is critical to the success of…
- Trial name
- IVFOD (NCT02952105)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Affiliated Hospital of Henan University of Science and Technology
Atrial Fibrillation, Atrial Flutter
Trial of Electrical Versus Pharmacological Cardioversion for RAFF in the ED
Atrial fibrillation (AF) and atrial flutter (AFL) are cardiac rhythm problems where there is an irregular, rapid heart rate. Investigators plan to study Emergency Department (ED) patients with recent-onset episodes of AF or AFL…
- Trial name
- RAFF-2 (NCT01891058)
- Testing
- drug-shock vs shock only
- Where
- 10 sites in Canada
- Volunteers
- 396 people
- Sponsor
- Ottawa Hospital Research Institute
Atrial Fibrillation, Defibrillators
Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion
Atrial fibrillation (AF) is a common cardiac arrhythmia that leads to increased risk of heart failure, hospitalization, thromboembolic events, and death.
- Conditions
- Atrial Fibrillation, Defibrillators, Persistent Atrial Fibrillation
- Trial name
- NCT03827915
- Testing
- Double sequential external defibrillation
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- American University of Beirut Medical Center
Atrial Fibrillation
Heart Rhythm Changes in Patients With Atrial Fibrillation After Cardiopulmonary Bypass: a Retrospective Analysis
The goal of this observational study is to learn about the lthe effect of the tetralogy of medication regimen on intraoperative cardioversion in patients with persistent AF.
- Trial name
- NCT06553391
- Testing
- The tetralogy of medication regimen
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Out-Of-Hospital Cardiac Arrest
The HeartRunner Trial
The study will assess 30-day survival for cases where volunteer citizen responders ('heart runners') were activated through a smartphone app to retrieve an AED in case of suspected out-of-hospital cardiac arrest (OHCA) versus…
- Trial name
- NCT03835403
- Testing
- Activation of HeartRunners
- Where
- Denmark
- Volunteers
- 2,114 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Hypothermia, Accidental, Defibrillation
Defibrillation in Accidental Hypothermia
Hypothermia (core temperature ≤35°C) is a frequent and life-threatening complication after mountain accidents, near-drowning, and intoxications, and can provoke arrhythmia, reduced cardiac contractility, and cardiac arrest.
- Trial name
- NCT06131892
- Testing
- Defibrillation
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- University Hospital, Geneva