Clinical trials: Caries Active
Dental Caries, Oral Bacterial Infection
Ecological Effect of Arginine Dentifrice on Oral Microbiota
caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8%…
- Conditions
- Dental Caries, Oral Bacterial Infection, Microbiota
- Trial name
- NCT02988349
- Testing
- Colgate® Sensitive Pro-Relief® toothpaste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Dental Caries
Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Evidence that the data flow analysis tests, there are still no studies that show the clarity of the protocols of its application, including the interval and execution factors of applications, concentration of fluoridation and…
- Trial name
- CEPECO3 (NCT03827889)
- Testing
- WMP of fluoride varnish, TWLP of fluoride varnish, DHP (educational intervention)
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Universidade Ibirapuera
Dental Caries
Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults
Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs.
- Trial name
- NCT06003452
- Testing
- surface treatment with Bioactive Glass Air Abrasion
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Streptococcal Infections
Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children.
A randomized controlled trial that compares the antibacterial effectiveness of three mouthwashes-licorice, clove, and chlorhexidine-in Egyptian children aged 7-12 years.
- Conditions
- Dental Caries, Streptococcal Infections, Mouthwashes
- Trial name
- NCT07828171
- Testing
- Mouth wash
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- British University In Egypt
Primary Teeth, Microbial Colonization
The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth
To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).
- Conditions
- Primary Teeth, Microbial Colonization, Caries, Dental Caries in Children
- Trial name
- NCT05221749
- Testing
- Nanosilver Fluoride (NSF), Silver diamine fluoride
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nour Ammar, BDS
Dental Caries
Effect of Silver Diamine Fluoride and LED Activation on Residual Caries Activity in Class II Cavities
This observational clinical study investigates the effect of silver diamine fluoride (SDF) and its activation with light-emitting diode (LED) on residual caries activity after caries excavation in Class II primary molar cavities.
- Trial name
- NCT07250009
- Testing
- DIAGNOdent measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Caries
Evaluation of the Salivary-free Amino Acids Levels (Glycine , Proline , Lysine , and Alanine ) With Caries Activity
This study will be aimed to investigated the correlation between levels of salivary amino acids (glycine , proline , lysine , alanine ) in the saliva of healthy children with and without active carious lesions and to estimate the…
- Trial name
- NCT06953557
- Testing
- To compare the effect of salivary glycine , proline , lysine and alanine concentration between participants with high caries activity and participants with negative caries activity
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Dentine Caries
Diamine Silver Fluoride and Potassium Iodide
Dental caries is an infectious disease mediated by a consortium of microbes in the oral cavity. The disease is characterized by demineralization of the tooth, if untreated, it leads to cavitation, discomfort, pain and eventual…
- Trial name
- NCT02771704
- Testing
- Silver Diamine fluoride, Potassium iodide, Chlorhexidine
- Volunteers
- 5 people
- Sponsor
- Kuwait University
Dentin Hypersensitivity, Active Dental Caries
Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth
This observational cohort study aims to evaluate the short-term (3 months) efficacy of the standard fluoride therapy in the German National Health System for managing hypersensitive carious lesions in primary teeth (fluoride…
- Trial name
- NCT04804423
- Testing
- 38% Silver Fluoride and Potassium Iodide solution (generic name; Riva Star®), Sodium fluoride varnish (generic name; Duraphat®)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Medicine Greifswald
Anxiety, Nursing Caries
The Effect of Mindfulness-Based Mandala Activity on Anxiety and Spiritual Well-Being Levels of Senior Nursing Students
This research was conducted to determine the effect of mindfulness-based mandala activity on the spiritual well-being and anxiety levels of senior nursing students in a parallel-group pretest-posttest randomized controlled study…
- Conditions
- Anxiety, Nursing Caries, ART
- Trial name
- NCT05053178
- Testing
- Mindfulness-based mandala activity
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Gazi University
Healthy
Investigation of the Relationship Between Taste Perception and Caries Activity in School Children
Four basic taste perceptions and relationship with caries are poorly investigated in children as compared to adults. The aim of this study was to evaluate salty, sweet, bitter and sour taste perceptions of school children and…
- Trial name
- NCT03468946
- Testing
- salty taste perception, bitter taste perception, sour taste perception
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Caries, Plaque
Dental Plaque Microbiota in Caries-free and Caries-active Children
Dental caries is a polymicrobial infection originally thought to be caused by Streptococcus mutans and Lactobacilli. However, unprecedented developments in modern molecular techniques have demonstrated that several microbial…
- Trial name
- NCT03906981
- Testing
- Plaque from each subject will be collected but there will be no intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Caries Active
Bioceramic Putty Versus MTA in Pulpotomized Primary Teeth to be Covered With 3D Printed Resin Crowns Versus Stainless Steel Crown
children aged 5 to 7 years with deep carious second primary molars that require vital pulp therapy will be treated using either MTA or bioceramic putty, then will be fully covered using either stainless steel crowns or 3D printed…
- Trial name
- NCT07344038
- Testing
- Endo-sequence bioceramic putty pulpotomy, Bio MTA+ pulpotomy, Stainless Steel Crowns (SSCs)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Dental Caries
Caries Lesion Activity in Orthodontic Patients - Calcivis System
This is a prospective, single-centre clinical study to monitor caries lesion activity in orthodontic patients with the Calcivis System over a 12 week period.
- Trial name
- NCT02771522
- Testing
- Calcivis System
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Calcivis Ltd
Dental Caries
Nanosilver Fluoride to Prevent Dental Biofilms Growth
This study aims to evaluate the effectiveness of nanosilver fluoride for controlling the growth of S. mutans present in dental plaque of children.
- Trial name
- NSFCT (NCT01950546)
- Testing
- nanosilver fluoride
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Caries Active, Prevention
Children in the Operating Room: Kids That go Thru Operating Room Will be Given a Connected Health Toothbrush, Kids Anticavity Toothpaste and Behavioral Health Intervention to Reduce Claim Costs
The objective of this study is to demonstrate that compliance and brushing adherence as a treatment to providers, insurance company and State Health Departments that can help improve oral health of children who have already been…
- Trial name
- NCT07539064
- Testing
- Connected Toothbrush with a behavioral health intervention
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Colgate Palmolive
Dental Caries in Children
Comparing the Effectiveness of Papain Based Chemico-mechanical Caries Removal Gel and 38% Silver Diamine Fluoride for Treating Active Caries Lesion of Primary Molars
This study aims to investigate the efficacy of silver diamine fluoride (SDF) and Papain-based chemico-mechanical caries removal gel and using ceramic bur as a control in treating dentine caries in primary molars aged 7-8 years…
- Trial name
- NCT06412731
- Testing
- Cera-bur, Brix3000, E-SDF
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Pulpotomy, Dental Caries
Pain and Anxiety Reducing During Dental Treatment in Children Using Video Game on Tablet Device With Joystick.
The aim of this study is to evaluate the effectiveness of two different distraction techniques (Audio Video Distraction /Video Game Distraction) in the management of anxious pediatric patients during dental treatment.
- Conditions
- Pulpotomy, Dental Caries, Primary Teeth
- Trial name
- NCT05191836
- Testing
- Evaluation of the effectiveness of Video Game Distraction in the management of anxious pediatric patients during dental treatment, Evaluation of the effectiveness of Audio Video Distraction in the management of anxious pediatric patients during dental treatment, Evaluation of the anxiety in pediatric patients during dental treatment without using any type of distraction aids
- Where
- Syria
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Damascus University
Childhood Obesity
The Impact of the "Nutrition Enrichment and Healthy Living Model" ( NEHLM) on Diet Quality, Physical Activity and Dental Health Among Children From Socioeconomically Disadvantaged Families in Beer Sheva
Childhood socioeconomic status (SES) is related to poor physical health, obesity, elevated cardiovascular risk factors and iron deficiency anemia.
- Trial name
- NEHLM (NCT01071551)
- Testing
- Life-style intervention, Physical activity only
- Where
- Israel
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Dental Caries
Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients
90 saliva samples will be isolated from patient who possess different ages and caries activity, attending outpatient clinic of October University of Modern Sciences and Arts.
- Trial name
- NCT03802669
- Testing
- oral mutans streptococcus
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts