Clinical trials: Cesarean
Infant, Newborn, Diseases, Fetus or Neonate Affected by Cesarean Section
HeartLight: Heart Rate Monitoring for Newborn Resuscitation
This study will compare a newborn heart rate sensor (HeartLight) that is integrated into a hat with other common forms of heart rate monitoring such as electrocardiography (ECG), stethoscope and pulse oximetry (PO) in newborn…
- Conditions
- Infant, Newborn, Diseases, Fetus or Neonate Affected by Cesarean Section, Infant, Premature, Diseases
- Trial name
- HeartLight (NCT02701920)
- Testing
- HeartLight hat, The HeartLight hat with in-built sensor, HeartLight
- Where
- United Kingdom
- Volunteers
- 184 people
- Sponsor
- University of Nottingham
Pregnancy
Previous Cesarean Sections
This is a retrospective chart review. The purpose is to look at the outcomes for women and newborns who decided to attempt a trial of labor after 3 or more previous cesarean sections.
- Trial name
- NCT03024632
- Testing
- Trial of labor
- Sponsor
- St. Louis University
Surgical Wound Infection
Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section
Many solutions are used for cleaning the skin of a patient previous to a surgery. Although the efficacy of clorhexidine has been proved in other surgical procedures, there is only a retrospective study in cesarean section (they…
- Trial name
- NCT01741649
- Testing
- Clorhexidine, Povidone
- Where
- Panama
- Volunteers
- 800 people
- Sponsor
- Saint Thomas Hospital, Panama
Cesarean Section Complications
Ultrasound Evaluation of Inferior Vena Cava Compression During Elective Cesarean Delivery.
Aortocaval compression by the gravid uterus during the third trimester contributes to decreased venous return to the heart. Neuraxial anesthesia reinforces this hypotension by causing a vasodilatation and venous pooling of blood…
- Trial name
- NCT03410199
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Pregnancy
Closure of Uterine Incision by Single or Double Layer Technique
The study compares short-term and long-term effects on myometrial thickness in women sutured by single- or double-layer technique by closure of cesarean uterine incision. The study is a randomized clinically controlled study.
- Trial name
- NCT02144805
- Testing
- Suturing in a single layer, Suturing in two layer
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Zealand University Hospital
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Research Objective: Primary outcome -To compare efficacy Intrauterine vs Sublingual MISOPROSTOL in addition to Oxytocin in reducing blood loss of post-cesarean section in high risk women Secondary outcome -To study…
- Trial name
- NCT04560218
- Testing
- sublingual Misoprostol, Intrauterine Misoprostol
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Cesarean Section Complications
The Effect of Primary Cesarean Section Prevention on Maternal and Neonatal Outcomes
The study aimed to examine the effect of prolonging the second stage of labor on the rate of Cesarean section (CS), maternal and neonatal outcomes. The study compared 2 time periods.
- Trial name
- NCT03640702
- Testing
- Protocol change
- Where
- Israel
- Volunteers
- 20,000 people
- Sponsor
- Rambam Health Care Campus
Pregnancy, Premature Rupture of Membranes
Cervical Ripening in Premature Rupture of Membranes
Premature rupture of membranes (PROM) is diagnosed by demonstrating amniotic fluid in the vaginal canal before the onset of labor.
- Conditions
- Pregnancy, Premature Rupture of Membranes, Preterm Premature Rupture of Membranes, Unfavorable Cervix
- Trial name
- NCT02314728
- Testing
- Misoprostol, Oxytocin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Cesarean Scar Pregnancy
Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar Pregnancy
There are no universal treatment guidelines available. The ultimate purpose of the management of CSP is to simultaneously remove the pregnancy and successfully preserve the woman's fertility (Gonzalez \& Tulandi, 2017).
- Trial name
- NCT04379219
- Testing
- Methotrexate
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Mansoura University
Corticosteroids Adverse Reaction
Impact of Antenatal Steroids on Coagulation.
Aim of the research : 1- Detection of the presence or absence of any effect of antenatal corticosteroid administration on coagulopathy, fibrinolysis, and other haematological markers.
- Trial name
- NCT06312852
- Volunteers
- 45 people
- Sponsor
- Assiut University
Human Immunodeficiency Virus
Maternal-fetal CD4 Microchimerism in HiV Exposed Newborns After Spontaneous Delivery and Cesarean Section
The aim of this single centre study is to measure maternal CD4+ t-cells in HiV exposed Newborns after spontaneous birth in comparison to cesarean section. This may have an influence on the risk of vertical HiV transmission.
- Trial name
- NCT01450059
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain
Spinal Anesthesia for Cesarean Delivery: Bupivacaine With or Without Fentanyl
The safest form of anesthesia for Cesarean section is a spinal anesthetic. All spinal anesthetics contain a local anesthetic and/or a narcotic.
- Trial name
- NCT00808327
- Testing
- Bupivacaine, Bupivacaine, fentanyl
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postoperative Care
Early Mobilization and No Urinary Catheter After Cesarean for Improved Post Operative Recovery: A Randomized Trial
ERAS (Enhanced Recovery After Surgery) is a set of steps used around surgery to help patients recover faster and better. ERAS guidelines have been adopted in several surgical fields, and evidence-based recommendations have…
- Trial name
- NCT07851558
- Testing
- Enhanced Recovery protocol
- Where
- Israel
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Infection Prevention
PROPHYLACTIC ANTIBIOTICS PRIOR TO CESAREAN SECTION IN OBESE WOMEN
Surgical site infections are common and a cause of major morbidity. They are also more common in obese women. Cesarean sections are the most common surgery performed in the United States, therefore pregnant women are being faced…
- Trial name
- NCT01810354
- Testing
- Cefazolin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Nurse's Role, Breastfeeding
Effect of Skin to Skin Contact on Sucking Efficiency of Newborns and Breastfeeding Self Efficacy of Mothers in Cesarean Deliveries
Due to the separation of the mother and the baby after the cesarean section, initiation of breastfeeding by the mother of the newborn in the first hour of life is delayed.
- Trial name
- NCT05697653
- Testing
- Skin-to-Skin contact.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Anesthesia, Local
Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean Delivery
Postoperative pain is considered one of the major problems after abdominal operations, so proper pain control is one of the main issues in clinical practice.
- Trial name
- NCT04748224
- Testing
- Bupivacaine 0.25% Injectable Solution, bupivacaine plus dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anxiety in Pregnancy, Mood Disorder Due to Specified Medical Condition
Preventing Maternal Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery
Perinatal mental health disorders are the most prevalent perinatal comorbidity and are associated with the primary cause of maternal mortality in the United States (US) - suicide.
- Trial name
- NCT06949813
- Testing
- BE-OR: Brief Intervention to the Operating Room, Interaction: Facetime with Clinical Provider
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Surgical Site Infections
Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section
The efficacy and safety of a single dose of ampicillin/sulbactam compared to a single dose of cefuroxime at cord clamp for prevention of postcesarean infectious morbidity has not been assessed.
- Trial name
- NCT01138852
- Testing
- Ampicillin-sulbactam, Cefuroxime
- Volunteers
- 176 people
- Sponsor
- Attikon Hospital